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Dr Minh Huynh

Multi-Modal Microscopist

Ph: + 61 2 9351 7525
Fax: + 61 2 9351 7682

B.Med.Sc (Hons), 2002, USYD; PhD, 2007, USYD

Minh conducted her Honours project and PhD at the Department of Oral Pathology under the supervision of Professor Zoellner at Westmead Hospital, where she studied morphological changes of endothelium during apoptosis and mechanisms for tumour invasion. Following her PhD studies, she worked as a Postdoctoral Researcher for the Iron Metabolism and Chelation Program at the University of Sydney investigating intracellular trafficking of endosomes and mitochondria.

Minh provides technical support and training for research students and staff in a wide range of microscopy techniques, specialising in super-resolution microscopy (GSD and STED), serial block face scanning electron microscopy and correlative light and electron microscopy of biological samples. Minh manages the PC2 facilities for cell culture and the biomolecular laboratory. Minh is also involved in the design and running of seminar and workshops in tissue culture, fluorescence, confocal and super-resolution microscopy.

Research interests

  • Canalicular formation in apoptotic endothelial cells
  • Mechanisms for tumour cell invasion and metastasis
  • Intracellular trafficking of endosomes and mitochondria in iron overload disorders
  • Super-resolution microscopy (GSD and STED)
  • Serial block face scanning electron microscopy
  • Correlative light and electron microscopy

Selected publications

  • Giacci, MK, Bartlett, CA, Huynh, M, Kilburn, MR, Dunlop, SA, Fitzgerald, M, 2018, Three dimensional electron microscopy reveals changing axonal and myelin morphology along normal and partially injured optic nerves, Scientific Reports, Volume 8 Issue 1, 3979.
  • Santos M, Michael PL, Filipe EC, Chan AHP, Hung J, Tan RP, Lee BSL, Huynh M, Hawkins C, Waterhouse A, Bilek MMM, and Wise SG, 2018, Plasma Synthesis of Carbon-Based Nanocarriers for Linker-Free Immobilization of Bioactive Cargo, ACS Applied Nano Materials 1 (2), 580-594.
  • Cheng D, Shami G, Morsch M, Huynh M, Trimby P, Braet F, 2017, Relocation is the key to successful correlative fluorescence and scanning electron microscopy, Correlative Light and Electron Microscopy lll, Methods in Cell Biology, Vol 140, Academic Press, pp. 215-244.
  • Shami G, Cheng D, Huynh M, Vreuls C, Wisse E and Braet F 2016, 3-D EM exploration of the hepatic microarchitecture - lessons learned from large volume in situ serial sectioning, Scientific Reports, 6, 1-16.
  • Braet F, Cheng D, Huynh M, Henriquez J, Shami G and Lampe M 2014, Combining Wide-Field Super-Resolution Microscopy and Electron Tomography: Rendering Nanoscopic Correlative Arrays on Subcellular Architecture. In: Correlative Light and Electron Microscopy II, Vol 124, MCB, UK:Academic Press, pp. 129-150
  • Emmanuel, C, Huynh, M, Matthews, J, Kelly, E, Zoellner, H 2013, "TNF-alpha and TGF-beta synergistically stimulate elongation of human endothelial cells without transdifferentiation to smooth muscle cell phenotype", Cytokine, vol. 61, no.1, pp. 38-40
  • David, MS, Huynh, MD, Kelly, E, Rozos, H, Coleman, H, Rogers, G, Zoellner, H 2012, "Membrane and cytoplasmic marker exchange between malignant neoplastic cells and fibroblasts via intermittent contact: increased tumour cell diversity independent of genetic change", Journal of Pathology, vol 228, no.4, pp. 495-505
  • Kobayashi, K, Cheng, D, Huynh, M, Ratinac, KR, Thordarson, P, Braet, F 2012, "imaging Fluorescently Labeled Complexes by Means of Multidimensional Correlative Light and Transmission Electron Microscopy: Practical Considerations" Correlative Light and Electron Microscopy, Book Series: Methods in Cell Biology, vol. 111, pp. 1-20

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