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Dr Minh Huynh

Position
Microscopist, Biomolecular Imaging Specialist

Contact
Email:
Ph: + 61 2 9351 7525
Fax: + 61 2 9351 7682

Qualifications
B.Med.Sc (Hons), 2002, USYD; PhD, 2007, USYD

Background
Minh conducted her Honours project and PhD at the Department of Oral Pathology under the supervision of Professor Zoellner at Westmead Hospital, where she studied morphological changes of endothelium during apoptosis and mechanisms for tumour invasion. Following her PhD studies, she worked as a Postdoctoral Researcher for the Iron Metabolism and Chelation Program at the University of Sydney investigating intracellular trafficking of endosomes and mitochondria.

Role
Minh provides technical support and training for research students and staff in a wide range of microscopy techniques, specialising in super-resolution microscopy (GSD and STED), serial block face scanning electron microscopy and correlative light and electron microscopy of biological samples. Minh manages the PC2 facilities for cell culture and the biomolecular laboratory. Minh is also involved in the design and running of seminar and workshops in tissue culture, fluorescence, confocal and super-resolution microscopy.

Research interests

  • Canalicular formation in apoptotic endothelial cells
  • Mechanisms for tumour cell invasion and metastasis
  • Intracellular trafficking of endosomes and mitochondria in iron overload disorders
  • Super-resolution microscopy (GSD and STED)
  • Serial block face scanning electron microscopy
  • Correlative light and electron microscopy

Selected publications

  • Braet F, Cheng D, Huynh M, Henriquez J, Shami G and Lampe M 2014, Combining Wide-Field Super-Resolution Microscopy and Electron Tomography: Rendering Nanoscopic Correlative Arrays on Subcellular Architecture. In: Correlative Light and Electron Microscopy II, Vol 124, MCB, UK:Academic Press, pp. 129-150
  • Emmanuel, C, Huynh, M, Matthews, J, Kelly, E, Zoellner, H 2013, "TNF-alpha and TGF-beta synergistically stimulate elongation of human endothelial cells without transdifferentiation to smooth muscle cell phenotype", Cytokine, vol. 61, no.1, pp. 38-40
  • David, MS, Huynh, MD, Kelly, E, Rozos, H, Coleman, H, Rogers, G, Zoellner, H 2012, "Membrane and cytoplasmic marker exchange between malignant neoplastic cells and fibroblasts via intermittent contact: increased tumour cell diversity independent of genetic change", Journal of Pathology, vol 228, no.4, pp. 495-505
  • Kobayashi, K, Cheng, D, Huynh, M, Ratinac, KR, Thordarson, P, Braet, F 2012, "imaging Fluorescently Labeled Complexes by Means of Multidimensional Correlative Light and Transmission Electron Microscopy: Practical Considerations" Correlative Light and Electron Microscopy, Book Series: Methods in Cell Biology, vol. 111, pp. 1-20

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