2012

• Götz, J., Ittner, A., Ittner, L. (2012), Tau-targeted treatment strategies in Alzheimer's disease. British journal of pharmacology. 165(5), 1246-59. [Abstract]

2011

• Götz, J., Eckert, A., Matamales, M., Ittner, L., Liu, X. (2011), Modes of Aβ toxicity in Alzheimer's disease. Cellular and molecular life sciences : CMLS. 68(20), 3359-75. [Abstract]
• Ittner, A., Ke, Y., Eersel, J., Gladbach, A., Götz, J., Ittner, L. (2011), Brief update on different roles of tau in neurodegeneration. IUBMB Life. 63(7), 495-502. [Abstract]
• Hundelt, M., Fath, T., Selle, K., Oesterwind, K., Jordan, J., Schultz, C., Götz, J., von Engelhardt, J., Monyer, H., Lewejohann, L., Sachser, N., Bakota, L., Brandt, R. (2011), Altered phosphorylation but no neurodegeneration in a mouse model of tau hyperphosphorylation. Neurobiology of aging. 32(6), 991-1006. [Abstract]
• Attems, J., Ittner, A., Jellinger, K., Nitsch, R., Maj, M., Wagner, L., Götz, J., Heikenwalder, M. (2011), Reduced secretagogin expression in the hippocampus of P301L tau transgenic mice. Journal of Neural Transmission. 118(5), 737-745. [Abstract]
• Louis, J., Martens, E., Borghgraef, P., Lambrecht, C., Sents, W., Longin, S., Zwaenepoel, K., Pijnenborg, R., Landrieu, I., Lippens, G., Ledermann, B., Götz, J., Van Leuven, F., Goris, J., Janssens, V. (2011), Mice lacking phosphatase PP2A subunit PR61/B'delta (Ppp2r5d) develop spatially restricted tauopathy by deregulation of CDK5 and GSK3beta. Proceedings of the National Academy of Sciences of the United States of America. 108(17), 6957-6962. [Abstract]
• Ittner, L., Götz, J. (2011), Amyloid-β and tau - a toxic pas de deux in Alzheimer's disease. Nature reviews. Neuroscience. 12(2), 65-72. [Abstract]
• van Eersel, J., Ke, Y., Gladbach, A., Bi, M., Götz, J., Kril, J., Ittner, L. (2011), Cytoplasmic Accumulation and Aggregation of TDP-43 upon Proteasome Inhibition in Cultured Neurons. PloS one. 6(7), e22850. [Abstract]
• Bi, M., Ittner, A., Ke, Y., Götz, J., Ittner, L. (2011), Tau-Targeted Immunization Impedes Progression of Neurofibrillary Histopathology in Aged P301L Tau Transgenic Mice. PLoS One. 6(12), e26860. [Abstract]
• Liu, X., Dobbie, M., Tunningley, R., Whittle, B., Zhang, Y., Ittner, L., Götz, J. (2011), ENU Mutagenesis Screen to Establish Motor Phenotypes in Wild-Type Mice and Modifiers of a Pre-Existing Motor Phenotype in Tau Mutant Mice. Journal of Biomedicine & Biotechnology. 2011, 130947. [Abstract]
• Lim, Y., Grimm, A., Giese, M., Mensah-Nyagan, A., Villafranca, J., Ittner, L., Eckert, A., Götz, J. (2011), Inhibition of the mitochondrial enzyme ABAD restores the amyloid-β-mediated deregulation of estradiol. PLoS One. 6(12), e28887. [Abstract]
• Gotz, J., Ittner, L., Gotz, N., Lam, H., Nicholas, H. (2011), Invertebrate and Vertebrate Models of Tauopathies. In: Animal Models for Neurodegenerative Disease. (pp.69-85).Cambridge: RSC Publishing.

2010

• Pienaar, I., Götz, J., Feany, M. (2010), Parkinson's disease: Insights from non-traditional model organisms. Progress in neurobiology. 92, 558-71. [Abstract]
• Götz, J., Gladbach, A., Pennanen, L., van Eersel, J., Schild, A., David, D., Ittner, L. (2010), Animal models reveal role for tau phosphorylation in human disease. Biochimica et biophysica acta. 1802(10), 860-71. [Abstract]
• Köhler, C., Bista, P., Götz, J., Schröder, H. (2010), Analysis of the cholinergic pathology in the P301L tau transgenic pR5 model of tauopathy. Brain Research. 1347, 111-124. [Abstract]
• Ittner, L., Ke, Y., Delerue, F., Bi, M., Gladbach, A., van Eersel, J., Wölfing, H., Chieng, B., Christie, M., Napier, I., Eckert, A., Staufenbiel, M., Hardeman, E., Götz, J. (2010), Dendritic Function of Tau Mediates Amyloid-beta Toxicity in Alzheimer's Disease Mouse Models. Cell. 142(3), 387-97. [Abstract]
• van Eersel, J., Ke, Y., Liu, X., Delerue, F., Kril, J., Götz, J., Ittner, L. (2010), Sodium selenate mitigates tau pathology, neurodegeneration, and functional deficits in Alzheimer's disease models. Proceedings of the National Academy of Sciences of the United States of America. 107(31), 13888-93. [Abstract]
• Eckert, A., Schulz, K., Rhein, V., Götz, J. (2010), Convergence of amyloid-beta and tau pathologies on mitochondria in vivo. Molecular Neurobiology. 41(2-3), 107-114. [Abstract]
• Krupka, N., Strappe, P., Götz, J., Ittner, L. (2010), Gateway-compatible lentiviral transfer vectors for ubiquitin promoter driven expression of fluorescent fusion proteins. Plasmid. 63(3), 155-160. [Abstract]
• Lim, Y., Rhein, V., Baysang, G., Meier, F., Poljak, A., J Raftery, M., Guilhaus, M., Ittner, L., Eckert, A., Götz, J. (2010), Abeta and human amylin share a common toxicity pathway via mitochondrial dysfunction. Proteomics. 10(8), 1621-33. [Abstract]
• Götz, J., Lim, Y., Ke, Y., Eckert, A., Ittner, L. (2010), Dissecting toxicity of tau and beta-amyloid. Neurodegenerative Diseases. 7(1-3), 10-12. [Abstract]
• Schonrock, N., Ke, Y., Humphreys, D., Staufenbiel, M., Ittner, L., Preiss, T., Götz, J. (2010), Neuronal MicroRNA Deregulation in Response to Alzheimer's Disease Amyloid-beta. PLoS One. 5(6), e11070. [Abstract]

2009

• Rhein, V., Song, X., Wiesner, A., Ittner, L., Baysang, G., Meier, F., Ozmen, L., Bluethmann, H., Dröse, S., Brandt, U., Savaskan, E., Czech, C., Götz, J., Eckert, A. (2009), Amyloid-beta and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice. Proceedings of the National Academy of Sciences of the United States of America. 106(47), 20057-20062. [Abstract]
• van Eersel, J., Bi, M., Ke, Y., Hodges, J., Xuereb, J., Gregory, G., Halliday, G., Götz, J., Kril, J., Ittner, L. (2009), Phosphorylation of soluble tau differs in Pick's disease and Alzheimer's disease brains. Journal of neural transmission (Vienna, Austria : 1996). 116(10), 1243-51. [Abstract]
• Ittner, L., Ke, Y., Gotz, J. (2009), Phosphorylated tau interacts with c-JUN N-terminal kinase (JNK) interacting protein 1 (JIP1) in Alzheimer's disease. The Journal of biological chemistry. 284(31), 20909-16. [Abstract]
• G��tz, J., Ittner, L., Lim, Y. (2009), Response to the comment 'Iron, type 2 diabetes mellitus, and Alzheimer's disease' to our Visions and Reflections article 'Common features between diabetes mellitus and Alzheimer's disease'. Cellular and Molecular Life Sciences. 66(17), 2945. [Abstract]
• Götz, J., Ittner, L., Lim, Y. (2009), Common features between diabetes mellitus and Alzheimer's disease. Cellular and molecular life sciences. 66(8), 1321-1325. [Abstract]
• Deters, N., Ittner, L., Götz, J. (2009), Substrate-specific reduction of PP2A activity exaggerates tau pathology. Biochemical and biophysical research communications. 379(2), 400-405. [Abstract]
• Götz, J., Schonrock, N., Vissel, B., Ittner, L. (2009), Alzheimer's Disease Selective Vulnerability and Modelling in Transgenic Mice. Journal of Alzheimer's disease : JAD. 18(2), 243-51. [Abstract]
• Ke, Y., Delerue, F., Gladbach, A., Götz, J., Ittner, L. (2009), Experimental Diabetes Mellitus Exacerbates Tau Pathology in a Transgenic Mouse Model of Alzheimer's Disease. PLoS One. 4(11), e7917. [Abstract]
• Fath, T., Ke, Y., Gunning, P., Götz, J., Ittner, L. (2009), Primary support cultures of hippocampal and substantia nigra neurons. Nature protocols. 4(1), 78-85. [Abstract]

2008

• Götz, J., Ittner, L., Schonrock, N., Cappai, R. (2008), An update on the toxicity of Abeta in Alzheimer's disease. Neuropsychiatric disease and treatment. 4(6), 1033-1042. [Abstract]
• Eckert, A., Hauptmann, S., Scherping, I., Meinhardt, J., Rhein, V., Dröse, S., Brandt, U., Fändrich, M., Müller, W., Götz, J. (2008), Oligomeric and fibrillar species of beta-amyloid (A beta 42) both impair mitochondrial function in P301L tau transgenic mice. Journal of molecular medicine. 86(11), 1255-67. [Abstract]
• Ittner, L., Fath, T., Ke, Y., Bi, M., van Eersel, J., Li, K., Gunning, P., Götz, J. (2008), Parkinsonism and impaired axonal transport in a mouse model of frontotemporal dementia. Proceedings of the National Academy of Sciences of the United States of America. 105(41), 15997-6002. [Abstract]
• Pienaar, I., Daniels, W., Götz, J. (2008), Neuroproteomics as a promising tool in Parkinson's disease research. Journal of neural transmission. 115(10), 1413-30. [Abstract]
• Einfeld, S., Götz, J., Holsinger, R. (2008), Pathogenetic mechanisms in Down Syndrome. Journal of intellectual disability research. 52(10), 813. [Abstract]
• Götz, J., Ittner, L., Fändrich, M., Schonrock, N. (2008), Is tau aggregation toxic or protective: a sensible question in the absence of sensitive methods?. Journal of Alzheimer's disease. 14(4), 423-9. [Abstract]
• Deters, N., Ittner, L., Götz, J. (2008), Divergent phosphorylation pattern of tau in P301L tau transgenic mice. The European Journal of Neuroscience. 28(1), 137-147. [Abstract]
• Götz, J., Ittner, L. (2008), Animal models of Alzheimer's disease and frontotemporal dementia. Nature Reviews. Neuroscience. 9(7), 532-544. [Abstract]
• Lim, Y., Ittner, L., Lim, Y., Götz, J. (2008), Human but not rat amylin shares neurotoxic properties with Abeta42 in long-term hippocampal and cortical cultures. FEBS letters. 582(15), 2188-94. [Abstract]
• Baur, K., Rauer, M., Richter, K., Pagenstecher, A., Götz, J., Hausmann, J., Staeheli, P. (2008), Antiviral CD8 T cells recognize borna disease virus antigen transgenically expressed in either neurons or astrocytes. Journal of Virology. 82(6), 3099-3108. [Abstract]
• Eckert, A., Hauptmann, S., Scherping, I., Rhein, V., Müller-Spahn, F., Götz, J., Müller, W. (2008), Soluble beta-amyloid leads to mitochondrial defects in amyloid precursor protein and tau transgenic mice. Neuro-degenerative diseases. 5(3-4), 157-9. [Abstract]
• Götz, J., David, D., Hoerndli, F., Ke, Y., Schonrock, N., Wiesner, A., Fath, T., Bokhari, L., Lim, Y., Deters, N., Ittner, L. (2008), Functional genomics dissects pathomechanisms in tauopathies: mitosis failure and unfolded protein response. Neuro-Degenerative Diseases. 5(3-4), 179-181. [Abstract]
• Ittner, L., Schwerdtfeger, K., Kunz, T., Muff, R., Husmann, K., Grimm, C., Hafezi, F., Lang, K., Kurrer, M., Götz, J., Born, W., Fischer, J. (2008), Transgenic mice with ocular overexpression of an adrenomedullin receptor reflect human acute angle-closure glaucoma. Clinical science. 114(1), 49-58. [Abstract]

2007

• Habicht, G., Haupt, C., Friedrich, R., Hortschansky, P., Sachse, C., Meinhardt, J., Wieligmann, K., Gellermann, G., Brodhun, M., Götz, J., Halbhuber, K., Röcken, C., Horn, U., Fändrich, M. (2007), Directed selection of a conformational antibody domain that prevents mature amyloid fibril formation by stabilizing Abeta protofibrils. Proceedings of the National Academy of Sciences of the United States of America. 104(49), 19232-7. [Abstract]
• Hoerndli, F., Pelech, S., Papassotiropoulos, A., Götz, J. (2007), Abeta treatment and P301L tau expression in an Alzheimer's disease tissue culture model act synergistically to promote aberrant cell cycle re-entry. The European journal of neuroscience. 26(1), 60-72. [Abstract]
• Goetz, J., Chen, F. (2007), Glyoxalase I and Alzheimer's disease. In: Research Progress in Alzheimer's Disease and Dementia. Vol.1. (pp.0).United States: Nova Science Publishers.
• Götz, J., Deters, N., Doldissen, A., Bokhari, L., Ke, Y., Wiesner, A., Schonrock, N., Ittner, L. (2007), A decade of tau transgenic animal models and beyond. Brain pathology (Zurich, Switzerland). 17(1), 91-103. [Abstract]
• Burke, D., Hickie, I., Breakspear, M., Gotz, J. (2007), Possibilities for the prevention and treatment of cognitive impairment and dementia. British Journal of Psychiatry. 190, 371-372. [Abstract]
• Ittner, L., Götz, J. (2007), Pronuclear injection for the production of transgenic mice. Nature protocols. 2(5), 1206-1215. [Abstract]

2006

• David, D., Ittner, L., Gehrig, P., Nergenau, D., Shepherd, C., Halliday, G., Götz, J. (2006), beta-Amyloid treatment of two complementary P301L tau-expressing Alzheimer's disease models reveals similar deregulated cellular processes. Proteomics. 6(24), 6566-77. [Abstract]
• Schild, A., Schmidt, K., Lim, Y., Ke, Y., Ittner, L., Hemmings, B., Götz, J. (2006), Altered levels of PP2A regulatory B/PR55 isoforms indicate role in neuronal differentiation. International journal of developmental neuroscience. 24(7), 437-443. [Abstract]
• Götz, J., Ittner, L., Schonrock, N. (2006), Alzheimer's disease and frontotemporal dementia: prospects of a tailored therapy?. The Medical journal of Australia. 185(7), 381-384. [Abstract]
• Gotz, J. (2006), Transgenic animal models of Alzheimer's disease. European Neuropsychopharmacology. 16, S197-S197. [Abstract]
• Götz, J., Ittner, L., Kins, S. (2006), Do axonal defects in tau and amyloid precursor protein transgenic animals model axonopathy in Alzheimer's disease?. Journal of neurochemistry. 98(4), 993-1006. [Abstract]
• Pennanen, L., Wolfer, D., Nitsch, R., Götz, J. (2006), Impaired spatial reference memory and increased exploratory behavior in P301L tau transgenic mice. Genes, brain, and behavior. 5(5), 369-379. [Abstract]
• Schild, A., Ittner, L., Götz, J. (2006), Altered phosphorylation of cytoskeletal proteins in mutant protein phosphatase 2A transgenic mice. Biochemical and biophysical research communications. 343(4), 1171-1178. [Abstract]
• Schild, A., Isenmann, S., Tanimoto, N., Tonagel, F., Seeliger, M., Ittner, L., Kretz, A., Ogris, E., Götz, J. (2006), Impaired development of the Harderian gland in mutant protein phosphatase 2A transgenic mice. Mechanisms of development. 123(5), 362-371. [Abstract]
• Kulic, L., Kurosinski, P., Chen, F., Tracy, J., Mohajeri, M., Li, H., Nitsch, R., Götz, J. (2006), Active immunization trial in Abeta(42)-injected P301L tau transgenic mice. Neurobiology of disease. 22(1), 50-6. [Abstract]
• Tam, C., Husmann, K., Clark, N., Clark, J., Lazar, Z., Ittner, L., Götz, J., Douglas, G., Grant, A., Sugden, D., Poston, L., Poston, R., McFadzean, I., Marber, M., Fischer, J., Born, W., Brain, S. (2006), Enhanced vascular responses to adrenomedullin in mice overexpressing receptor-activity-modifying protein 2. Circulation research. 98(2), 262-70. [Abstract]
• Pei, J., An, W., Zhou, X., Nishimura, T., Norberg, J., Benedikz, E., Gotz, J., Winblad, B. (2006), P70S6 kinase mediates tau phosphorylation and synthesis. Febs Letters. 580(1), 107-114. [Abstract]
• Goetz, J., David, D., Ittner, L. (2006), Impact of beta-amyloid on the tau pathology in tau transgenic mouse and tissue culture models. In: Abeta Peptide and Alzheimer's Disease: Celebrating a Century of Research. (pp.198-215).United Kingdom: Springer.