Associate Professor Jim Lagopoulos

Associate Professor in Neuroimaging
Brain & Mind Research Institute, Sydney Medical School

T:+61 2 9351 0783
E:

Research interests

My research focus lies in the area of neuroimaging. Of particular interest is the interaction between prefrontal cortex and subcortical substrates in the regulation of emotion and how these networks are specialised for the detection of behaviourally relevant stimuli. In the area of neurophysiology, I have focussed on intraoperative techniques including electrocorticography in the planning of epilepsy surgery as well as techniques for mapping brain function during surgery for the resection of brain and spinal cord tumours.

Keywords

Behavioural neuroscience; Psychiatry; Brain injuries; Neuroimaging

Publications

2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007

2013

  
  • Dimou, S., Battisti, R., Hermens, D., Lagopoulos, J. (2013), A systematic review of functional magnetic resonance imaging and diffusion tensor imaging modalities used in presurgical planning of brain tumour resection. Neurosurgical Review. 36(2), 205-214. [Abstract]
  • Kassem, M., Lagopoulos, J., Stait-Gardner, T., Price, W., Chohan, T., Arnold, J., Hatton, S., Bennett, M. (2013), Stress-Induced Grey Matter Loss Determined by MRI Is Primarily Due to Loss of Dendrites and Their Synapses. Molecular Neurobiology. 47(2), 645-661. [Abstract]
  • Scott, E., Hermens, D., Naismith, S., Guastella, A., De Regt, T., White, D., Lagopoulos, J., Hickie, I. (2013), Distinguishing young people with emerging bipolar disorders from those with unipolar depression. Journal of Affective Disorders. 144(3), 208-215. [Abstract]
  • Hermens, D., Lagopoulos, J. (2013), Pathways to alcohol-induced brain impairment in young people: A review by Hermens et al., 2013: Reply. Cortex. , 1160-1161. [Abstract]
  • Lagopoulos, J., Hermens, D., Hatton, S., Battisti, R., Tobias-Webb, J., White, D., Naismith, S., Scott, E., Ryder, W., Bennett, M., Hickie, I. (2013), Microstructural white matter changes are correlated with the stage of psychiatric illness. Translational Psychiatry. 3, e248. [Abstract]
  • Hatton, S., Lagopoulos, J., Hermens, D., Scott, E., Hickie, I., Bennett, M. (2013), Cortical thinning in young psychosis and bipolar patients correlate with common neurocognitive deficits. International Journal of Bipolar Disorders. 1(3), 1-13.
  • Hermens, D., Naismith, S., Lagopoulos, J., Lee, R., Guastella, A., Scott, E., Hickie, I. (2013), Neuropsychological profile according to the clinical stage of young persons presenting for mental health care. BMC Psychology. 1, 3.
  • Hermens, D., Scott, E., White, D., Lynch, M., Lagopoulos, J., Whitwell, B., Naismith, S., Hickie, I. (2013), Frequent alcohol, nicotine or cannabis use is common in young persons presenting for mental healthcare: a cross-sectional study. BMJ open. 3(2), e002229. [Abstract]
  • Hermens, D., Lagopoulos, J., Tobias-Webb, J., De Regt, T., Dore, G., Juckes, L., Latt, N., Hickie, I. (2013), Pathways to alcohol-induced brain impairment in young people: A review. Cortex. 49(1), 3-17. [Abstract]
  • Lagopoulos, J., Hermens, D., Hatton, S., Tobias-Webb, J., Griffiths, K., Naismith, S., Scott, E., Hickie, I. (2013), Microstructural white matter changes in the corpus callosum of young people with bipolar disorder: a diffusion tensor imaging study. PloS One. 8(3), e59108. [Abstract]

2012

  
  • L, W., D F, H., I B, H., J, L. (2012), A systematic review of resting-state functional-MRI studies in major depression. Journal of Affective Disorders. 142(1-3), 6-12. [Abstract]
  • Kaur, M., Battisti, R., Lagopoulos, J., Ward, P., Hickie, I., Hermens, D. (2012), Neurophysiological biomarkers support bipolar-spectrum disorders within psychosis cluster. Journal of Psychiatry & Neuroscience. 37(5), 313-321. [Abstract]
  • Hatton, S., Lagopoulos, J., Hermens, D., Naismith, S., Bennett, M., Hickie, I. (2012), Correlating anterior insula gray matter volume changes in young people with clinical and neurocognitive outcomes: an MRI study. BMC Psychiatry. 12(1), 45. [Abstract]
  • Degabriele, R., Lagopoulos, J. (2012), Delayed early face processing in bipolar disorder. Neuroreport. 23(3), 152-6. [Abstract]
  • Das, P., Lagopoulos, J., Coulston, C., Henderson, A., Malhi, G. (2012), Mentalizing impairment in schizophrenia: A functional MRI study. Schizophrenia Research. 134(2-3), 158-164. [Abstract]
  • Lagopoulos, J., Hermens, D., Naismith, S., Scott, E., Hickie, I. (2012), Frontal lobe changes occur early in the course of affective disorders in young people. BMC psychiatry. 12(1), 4. [Abstract]
  • Hermens, D., Lagopoulos, J., Naismith, S., Tobias-Webb, J., Hickie, I. (2012), Distinct neurometabolic profiles are evident in the anterior cingulate of young people with major psychiatric disorders. Translational Psychiatry. 2, e110. [Abstract]
  • Kaur, M., Lagopoulos, J., Ward, P., Watson, T., Naismith, S., Hickie, I., Hermens, D. (2012), Mismatch negativity/p3a complex in young people with psychiatric disorders: a cluster analysis. PLoS One. 7(12), e51871. [Abstract]

2011

  
  • Chitty, K., Kaur, M., Lagopoulos, J., Hickie, I., Hermens, D. (2011), Alcohol use and mismatch negativity in young patients with psychotic disorder. Neuroreport. 22(17), 918-22. [Abstract]
  • Degabriele, R., Lagopoulos, J., Malhi, G. (2011), Neural correlates of emotional face processing in bipolar disorder: An event-related potential study. Journal of affective disorders. 133(1-2), 212-20. [Abstract]
  • Degabriele, R., Lagopoulos, J., Ward, P. (2011), Event-related potential correlates of inhibition in bipolar disorder. Neuroreport. 22(10), 484-8. [Abstract]
  • Lagopoulos, J., Malhi, G. (2011), Impairments in "top-down" processing in bipolar disorder: A simultaneous fMRI-GSR study. Psychiatry research. 192(2), 100-8. [Abstract]

2010

  
  • Naismith, S., Lagopoulos, J., Ward, P., Davey, C., Little, C., Hickie, I. (2010), Fronto-striatal correlates of impaired implicit sequence learning in major depression: An fMRI study. Journal of affective disorders. 125(1-3), 256-61. [Abstract]
  • Loo, C., Sachdev, P., Martin, D., Pigot, M., Alonzo, A., Malhi, G., Lagopoulos, J., Mitchell, P. (2010), A double-blind, sham-controlled trial of transcranial direct current stimulation for the treatment of depression. The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP). 13(1), 61-9. [Abstract]
  • Sharma, H., Lagopoulos, J. (2010), MRI physics: pulse sequences. Acta Neuropsychiatrica. 22(2), 90-92.
  • Malhi, G., Tannious, M., Cashman, E., Das, P., Lagopoulos, J. (2010), Picturing emotional distress?. Acta Neuropsychiatrica. 22(3), 150-151.
  • Norris, S., Degabriele, R., Lagopoulos, J. (2010), Recommendations for the use of tDCS in clinical research. Acta Neuropsychiatrica. 22(4), 197-198.
  • Lagopoulos, J. (2010), Evolution of brain imaging in neuropsychiatry: past, present and future. Acta Neuropsychiatrica. 22(3), 152-154.

2009

  
  • Lagopoulos, J., Xu, J., Rasmussen, I., Vik, A., Malhi, G., Eliassen, C., Arntsen, I., Saether, J., Hollup, S., Holen, A., Davanger, S., Ellingsen, O. (2009), Increased Theta and Alpha EEG Activity During Nondirective Meditation. Journal of Alternative & Complementary Medicine. 15(11), 1187-1192. [Abstract]
  • Lagopoulos, J. (2009), Quantification of brain metabolites. Acta Neuropsychiatrica. 21(3), 143-144. [Abstract]
  • Das, P., Lagopoulos, J. (2009), Connectivity. Acta Neuropsychiatrica. 21(2), 91-92.
  • Degabriele, R., Lagopoulos, J. (2009), A review of EEG and ERP studies in bipolar disorder. Acta Neuropsychiatrica. 21(2), 58-66. [Abstract]

2008

  
  • Hsu, B., Cree, A., Lagopoulos, J., Cummine, J. (2008), Transcranial motor-evoked potentials combined with response recording through compound muscle action potential as the sole modality of spinal cord monitoring in spinal deformity surgery. Spine. 33(10), 1100-6. [Abstract]
  • Fornito, A., Malhi, G., Lagopoulos, J., Ivanovski, B., Wood, S., Saling, M., Pantelis, C., Yücel, M. (2008), Anatomical abnormalities of the anterior cingulate and paracingulate cortex in patients with bipolar I disorder. Psychiatry Research. 162(2), 123-132. [Abstract]
  • Malhi, G., Lagopoulos, J. (2008), Making sense of neuroimaging in psychiatry. Acta psychiatrica Scandinavica. 117, 100-17. [Abstract]
  • Saether, O., Das, P., Lagopoulos, J. (2008), Spectroscopy: technical perspectives. Acta Neuropsychiatrica. 20(3), 159-161.
  • Das, P., Lagopoulos, J., Saether, O., Malhi, G. (2008), Is Computed Tomography still a useful neuroimaging tool in psychiatry?. Expert Opinion on Medical Diagnostics. 2, 1003-1011.
  • Malhi, G., Lagopoulos, J., Das, P., Moss, K., Berk, M., Coulston, C. (2008), A functional MRI study of Theory of Mind in euthymic bipolar disorder patients. Bipolar Disorders. 10(8), 943-956. [Abstract]
  • Lagopoulos, J., Degabriele, R. (2008), Feeling the heat: the electrode-skin interface during DCS. Acta Neuropsychiatrica. 20, 98-100.
  • Berntsen, E., Samuelsen, P., Lagopoulos, J., Rasmussen, I., Haberg, A., Haraldseth, O. (2008), Mapping the primary motor cortex in healthy subjects and patients with peri-rolandic brain lesions before neurosurgery. Neurological Research. 30(9), 968-973. [Abstract]

2007

  
  • Fornito, A., Malhi, G., Lagopoulos, J., Ivanovski, B., Wood, S., Velakoulis, D., Saling, M., McGorry, P., Pantelis, C., Yücel, M. (2007), In vivo evidence for early neurodevelopmental anomaly of the anterior cingulate cortex in bipolar disorder. Acta psychiatrica Scandinavica. 116(6), 467-472. [Abstract]
  • Lagopoulos, J., Malhi, G. (2007), A functional magnetic resonance imaging study of emotional Stroop in euthymic bipolar disorder. Neuroreport. 18(15), 1583-1587. [Abstract]
  • Malhi, G., Lagopoulos, J., Sachdev, P., Ivanovski, B., Shnier, R., Ketter, T. (2007), Is a lack of disgust something to fear? A functional magnetic resonance imaging facial emotion recognition study in euthymic bipolar disorder patients. Bipolar disorders. 9(4), 345-357. [Abstract]
  • Lagopoulos, J., Ivanovski, B., Malhi, G. (2007), An event-related functional MRI study of working memory in euthymic bipolar disorder. Journal of Psychiatry and Neuroscience. 32(3), 174-184. [Abstract]
  • Xu, J., Rasmussen, I., Lagopoulos, J., Håberg, A. (2007), Diffuse axonal injury in severe traumatic brain injury visualized using high-resolution diffusion tensor imaging. Journal of neurotrauma. 24(5), 753-765. [Abstract]
  • Xu, J., Rasmussen, I., Berntsen, E., Moss, K., Shnier, R., Lagopoulos, J., Malhi, G. (2007), A growth in bipolar disorder?. Acta psychiatrica Scandinavica. 115(3), 246-50; discussion 250. [Abstract]
  • Malhi, G., Lagopoulos, J., Owen, A., Ivanovski, B., Shnier, R., Sachdev, P. (2007), Reduced activation to implicit affect induction in euthymic bipolar patients: An fMRI study. Journal of affective disorders. 97(1-3), 109-22. [Abstract]
  • Lagopoulos, J. (2007), Voxel-based morphometry made simple. Acta Neuropsychiatrica. 19, 213–214.
  • Lagopoulos, J. (2007), Spectroscopy. Acta Neuropsychiatrica. 19, 382–383.
  • Lagopoulos, J. (2007), Functional MRI: an overview. Acta Neuropsychiatrica. 19, 64–65.
  • Malhi, G., Ivanovski, B., Wen, W., Lagopoulos, J., Moss, K., Sachdev, P. (2007), Measuring mania metabolites: a longitudinal proton spectroscopy study of hypomania. Acta psychiatrica Scandinavica. Supplementum. 16(434), 57-66. [Abstract]
  • Malhi, G., Lagopoulos, J. (2007), Cutting edge neuropsychiatry. Acta Neuropsychiatrica. 19, 380-381.
  • Lagopoulos, J., Malhi, G. (2007), Modern neuroimaging: the meaning behind the pictures. Medicine Today. 8(8), 68-69.
  • Lagopoulos, J. (2007), Event-related potentials. Acta Neuropsychiatrica. 19, 256-257.
  • Lagopoulos, J. (2007), Electrodermal activity. Acta Neuropsychiatrica. 19, 316-317.
  • Lagopoulos, J. (2007), Diffusion tensor imaging: an overview. Acta Neuropsychiatrica. 19, 127-128.