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Publications list for Professor Michael Kassiou

2011 | 2010 | 2009 | 2008 | 2007 | 2006

2011

  
  • Crossley, E., Issa, F., Scarf, A., Kassiou, M., Rendina, L. (2011), Synthesis and cellular uptake of boron-rich pyrazolopyrimidines: exploitation of the translocator protein for the efficient delivery of boron into human glioma cells. Chemical communications (Cambridge, England). 47(44), 12179-81. [Abstract]
  • Moussa, I., Banister, S., Giboureau, N., Meikle, S., Kassiou, M. (2011), Synthesis and in vivo evaluation of [18F]N-(2-benzofuranylmethyl)-N'-[4-(2-fluoroethoxy)benzyl]piperazine, a novel ?1 receptor PET imaging agent. Bioorganic & medicinal chemistry letters. 21(22), 6820-3. [Abstract]
  • Moussa, I., Banister, S., Akladios, F., Chua, S., Kassiou, M. (2011), Effects of linker elongation in a series of N-(2-benzofuranylmethyl)-N'-(methoxyphenylalkyl)piperazine ??(1) receptor ligands. Bioorganic & medicinal chemistry letters. 21(19), 5707-10. [Abstract]
  • Banister, S., Yoo, D., Chua, S., Cui, J., Mach, R., Kassiou, M. (2011), N-Arylalkyl-2-azaadamantanes as cage-expanded polycarbocyclic sigma (??) receptor ligands. Bioorganic & medicinal chemistry letters. 21(18), 5289-92. [Abstract]
  • Issa, F., Kassiou, M., Rendina, L. (2011), Boron in Drug Discovery: Carboranes as Unique Pharmacophores in Biologically Active Compounds. Chemical reviews. 111(9), 5701-22. [Abstract]
  • Boucher, A., Arnold, J., Hunt, G., Spiro, A., Spencer, J., Brown, C., McGregor, I., Bennett, M., Kassiou, M. (2011), Resilience and reduced c-Fos expression in P2X7 receptor knockout mice exposed to repeated forced swim test. Neuroscience. 189(2011), 170-7. [Abstract]
  • Damont, A., Boisgard, R., Kuhnast, B., Lemée, F., Raggiri, G., Scarf, A., Da Pozzo, E., Selleri, S., Martini, C., Tavitian, B., Kassiou, M., Dollé, F. (2011), Synthesis of 6-[¹⁸F]fluoro-PBR28, a novel radiotracer for imaging the TSPO 18 kDa with PET. Bioorganic & Medicinal Chemistry Letters. 21(16), 4819-4822. [Abstract]
  • Drake, C., Boutin, H., Jones, M., Denes, A., McColl, B., Selvarajah, J., Hulme, S., Georgiou, R., Hinz, R., Gerhard, A., Vail, A., Prenant, C., Julyan, P., Maroy, R., Brown, G., Smigova, A., Herholz, K., Kassiou, M., Crossman, D., Francis, S., Proctor, S., Russell, J., Hopkins, S., Tyrrell, P., Rothwell, N., Allan, S. (2011), Brain inflammation is induced by co-morbidities and risk factors for stroke. Brain, Behavior, and Immunity. 25(6), 1113-1122. [Abstract]
  • Banister, S., Moussa, I., Jorgensen, W., Chua, S., Kassiou, M. (2011), Molecular hybridization of 4-azahexacyclo[5.4.1.0(2,6).0(3,10).0(5,9).0(8,11)]dodecane-3-ol with sigma (??) receptor ligands modulates off-target activity and subtype selectivity. Bioorganic & medicinal chemistry letters. 21(12), 3622-6. [Abstract]
  • Scarf, A., Kassiou, M. (2011), The Translocator Protein. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 52(5), 677-80. [Abstract]
  • Martín, A., Boisgard, R., Kassiou, M., Dollé, F., Tavitian, B. (2011), Reduced PBR/TSPO expression after minocycline treatment in a rat model of focal cerebral ischemia: a PET study using [(18)F]DPA-714. Molecular Imaging and Biology. 13(1), 10-15. [Abstract]
  • Banister, S., Moussa, I., Beinat, C., Reynolds, A., Schiavini, P., Jorgensen, W., Kassiou, M. (2011), Trishomocubane as a scaffold for the development of selective dopamine transporter (DAT) ligands. Bioorganic & medicinal chemistry letters. 21(1), 38-41. [Abstract]

2010

  
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  • Morrison, D., Issa, F., Bhadbhade, M., Groebler, L., Witting, P., Kassiou, M., Rutledge, P., Rendina, L. (2010), Boronated phosphonium salts containing arylboronic acid, closo-carborane, or nido-carborane: synthesis, X-ray diffraction, in vitro cytotoxicity, and cellular uptake. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry. 15, 1305-18. [Abstract]
  • Reynolds, A., Hanani, R., Hibbs, D., Damont, A., Pozzo, E., Selleri, S., Dollé, F., Martini, C., Kassiou, M. (2010), Pyrazolo[1,5-a]pyrimidine acetamides: 4-Phenyl alkyl ether derivatives as potent ligands for the 18kDa translocator protein (TSPO). Bioorganic & medicinal chemistry letters. 20(19), 5799-802. [Abstract]
  • Moussa, I., Banister, S., Beinat, C., Giboureau, N., Reynolds, A., Kassiou, M. (2010), Design, synthesis, and structure-affinity relationships of regioisomeric N-benzyl alkyl ether piperazine derivatives as sigma-1 receptor ligands. Journal of Medicinal Chemistry. 53(16), 6228-6239. [Abstract]
  • Gunosewoyo, H., Kassiou, M. (2010), P2X purinergic receptor ligands: recently patented compounds. Expert opinion on therapeutic patents. 20(5), 625-46. [Abstract]
  • Naidoo-Variawa, S., Lehnert, W., Kassiou, M., Banati, R., Meikle, S. (2010), Attenuation correction for the large non-human primate brain imaging using microPET. Physics in Medicine and Biology. 55(8), 2351-2363. [Abstract]
  • Banister, S., Moussa, I., Jordan, M., Coster, M., Kassiou, M. (2010), Oxo-bridged isomers of aza-trishomocubane sigma (sigma) receptor ligands: Synthesis, in vitro binding, and molecular modeling. Bioorganic & medicinal chemistry letters. 20(1), 145-148. [Abstract]
  • Banister, S., Clegg, J., Hanani, R., Kassiou, M. (2010), 11-{[2-(3-Fluorophenyl)ethyl](methyl)-amino}pentacyclo[5.4.0.02,6.03,10.05,9]-undecan-8-one. Acta Crystallographica. Section E: Structure Reports Online. 66(10), o2693.
  • Luus, C., Hanani, R., Reynolds, A., Kassiou, M. (2010), The development of PET radioligands for imaging the translocator protein (18 kDa): What have we learned?. Journal of Labelled Compounds and Radiopharmaceuticals. 53(7), 501-510.
  • Giboureau, N., Aumann, K., Beinat, C., Kassiou, M. (2010), Development of Vesicular Acetylcholine Transporter Ligands: Molecular Probes for Alzheimer's Disease. Current Bioactive Compounds. 6(3), 129-155.
  • Martin, A., Boisgard, R., Theze, B., Van Camp, N., Kuhnast, B., Damont, A., Kassiou, M., Dolle, F., Tavitian, B. (2010), Evaluation of the PBR/TSPO radioligand F-18 DPA-714 in a rat model of focal cerebral ischemia. Journal of Cerebral Blood Flow and Metabolism. 30(1), 230-241. [Abstract]
  • Beinat, C., Banister, S., Moussa, I., Reynolds, A., McErlean, C., Kassiou, M. (2010), Insights into Structure-Activity Relationships and CNS Therapeutic Applications of NR2B Selective Antagonists. Current medicinal chemistry. 17(34), 4166-90. [Abstract]
  • Giboureau, N., Som, I., Boucher-Arnold, A., Guilloteau, D., Kassiou, M. (2010), PET Radioligands for the Vesicular Acetylcholine Transporter (VAChT). Current Topics in Medicinal Chemistry. 10(15), 1569-1583. [Abstract]

2009

  
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  • Edington, A., McKinzie, A., Reynolds, A., Kassiou, M., Ryan, R., Vandenberg, R. (2009), Extracellular loops 2 and 4 of GLYT2 are required for N-arachidonyl-glycine inhibition of glycine transport. The Journal of biological chemistry. 284(52), 36424-30. [Abstract]
  • Leaver, K., Allbutt, H., Creber, N., Kassiou, M., Henderson, J. (2009), Oral pre-treatment with epigallocatechin gallate in 6-OHDA lesioned rats produces subtle symptomatic relief but not neuroprotection. Brain Research Bulletin. 80(6), 397-402. [Abstract]
  • Valette, H., Xiao, Y., Peyronneau, M., Damont, A., Kozikowski, A., Wei, Z., Kassiou, M., Kellar, K., Dollé, F., Bottlaender, M. (2009), 18F-ZW-104: A New Radioligand for Imaging Neuronal Nicotinic Acetylcholine Receptors--In Vitro Binding Properties and PET Studies in Baboons. Journal of nuclear medicine. 50(8), 1349-1355. [Abstract]
  • Endres, C., Pomper, M., James, M., Uzuner, O., Hammoud, D., Watkins, C., Reynolds, A., Hilton, J., Dannals, R., Kassiou, M. (2009), Initial Evaluation of 11C-DPA-713, a Novel TSPO PET Ligand, in Humans. Journal of nuclear medicine. 50(8), 1276-1282. [Abstract]
  • Gunosewoyo, H., Coster, M., Bennett, M., Kassiou, M. (2009), Purinergic P2X(7) receptor antagonists: Chemistry and fundamentals of biological screening. Bioorganic & medicinal chemistry. 17(14), 4861-5. [Abstract]
  • Henderson, J., Lanciego, J., Smith, Y., Gundlach, A., Kassiou, M. (2009), Proceedings of the 2007 International Brain Research Organisation Satellite Meeting "Movement Disorders: Focus on the Thalamus and Basal Ganglia" held in Sydney, Australia, 10-11 July, 2007. Brain research bulletin. 78, 53-4. [Abstract]
  • Truong, L., Allbutt, H., Coster, M., Kassiou, M., Henderson, J. (2009), Behavioural effects of a selective NMDA NR1A/2B receptor antagonist in rats with unilateral 6-OHDA+parafascicular lesions. Brain research bulletin. 78(0), 91-6. [Abstract]
  • Kassiou, M., Banati, R., Holsinger, R., Meikle, S. (2009), Challenges in molecular imaging of Parkinson's disease: A brief overview. Brain research bulletin. 78(0), 105-8. [Abstract]
  • Warraich, S., Allbutt, H., Billing, R., Radford, J., Coster, M., Kassiou, M., Henderson, J. (2009), Evaluation of behavioural effects of a selective NMDA NR1A/2B receptor antagonist in the unilateral 6-OHDA lesion rat model. Brain research bulletin. 78(0), 85-90. [Abstract]
  • Scarf, A., Ittner, L., Kassiou, M. (2009), The translocator protein (18 kDa): central nervous system disease and drug design. Journal of Medicinal Chemistry. 52(3), 581-592. [Abstract]
  • Dollé, F., Luus, C., Reynolds, A., Kassiou, M. (2009), Radiolabelled Molecules for Imaging the Translocator Protein (18 kDa) Using Positron Emission Tomography. Current medicinal chemistry. 16(22), 2899-2923. [Abstract]
  • Ioppolo, J., Kassiou, M., Rendina, L. (2009), Water-soluble phosphonium salts containing 1,12-dicarba-closo-dodecaborane(12). Tetrahedron Letters. 50, 6457-6461. [Abstract]
  • Doorduin, J., Klein, H., Dierckx, R., James, M., Kassiou, M., de Vries, E. (2009), [C-11]-DPA-713 and [F-18]-DPA-714 as New PET Tracers for TSPO: A Comparison with [C-11]-(R)-PK11195 in a Rat Model of Herpes Encephalitis. Molecular Imaging and Biology. 11, 386-398. [Abstract]
  • Chauveau, F., Van Camp, N., Dolle, F., Kuhnast, B., Hinnen, F., Damont, A., Boutin, H., James, M., Kassiou, M., Tavitian, B. (2009), Comparative Evaluation of the Translocator Protein Radioligands C-11-DPA-713, F-18-DPA-714, and C-11-PK11195 in a Rat Model of Acute Neuroinflammation. Journal of Nuclear Medicine. 50(3), 468-476. [Abstract]

2008

  
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  • Leaver, K., Allbutt, H., Creber, N., Kassiou, M., Henderson, J. (2008), NEUROPROTECTIVE EFFECTS OF A SELECTIVE N-METHYL-d-ASPARTATE NR2B RECEPTOR ANTAGONIST IN THE 6-HYDROXYDOPAMINE RAT MODEL OF PARKINSON'S DISEASE. Clinical and experimental pharmacology & physiology. 35(11), 1388-94. [Abstract]
  • Gunosewoyo, H., Guo, J., Bennett, M., Coster, M., Kassiou, M. (2008), Cubyl amides: Novel P2X(7) receptor antagonists. Bioorganic & medicinal chemistry letters. 18(13), 3720-3. [Abstract]
  • Besret, L., Dollé, F., Hérard, A., Guillermier, M., Demphel, S., Hinnen, F., Coulon, C., Ottaviani, M., Bottlaender, M., Hantraye, P., Kassiou, M. (2008), Dopamine D1 receptor imaging in the rodent and primate brain using the isoquinoline +-[11C]A-69024 and positron emission tomography. Journal of pharmaceutical sciences. 97(7), 2811-2819. [Abstract]
  • van Dijk, A., Johnston, C., Allbutt, H., Kassiou, M., Henderson, J. (2008), Behavioural effects of trishomocubanes in rats with unilateral 6-hydroxydopamine lesions. Behavioural Brain Research. 190(1), 14-21. [Abstract]
  • James, M., Fulton, R., Vercoullie, J., Henderson, D., Garreau, L., Chalon, S., Dolle, F., Selleri, S., Guilloteau, D., Kassiou, M. (2008), DPA-714, a New Translocator Protein-Specific Ligand: Synthesis, Radiofluorination, and Pharmacologic Characterization. Journal of nuclear medicine. 49(5), 814-822. [Abstract]
  • Damont, A., Hinnen, F., Kuhnast, B., Schollhorn-Peyronneau, M., James, M., Luus, C., Tavitian, B., Kassiou, M., Dolle, F. (2008), Radiosynthesis of [F-18]DPA-714, a selective radioligand for imaging the translocator protein (18 kDa) with PET. Journal of Labelled Compounds & Radiopharmaceuticals. 51(7-8), 286-292. [Abstract]
  • Dollé, F., Langle, S., Roger, G., Fulton, R., Lagnel-de Bruin, B., Henderson, D., Hinnen, F., Paine, T., Coster, M., Valette, H., Bottlaender, M., Kassiou, M. (2008), Synthesis and In-Vivo Evaluation of [11C]p-PVP-MEMA as a PET Radioligand for Imaging Nicotinic Receptors. Australian Journal of Chemistry. 61(6), 438–445.
  • Guenther, K., Hambley, T., Kassiou, M. (2008), Radiolabelled probes for imaging multidrug resistance using single photon emission tomography (SPECT) and positron emission tomography (PET). In: Multidrug Resistance: Biological and Pharmaceutical Advances in Antitumour Treatment. (pp.291-320).India: Research Signpost.

2007

  
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  • Naidoo-Variawa, S., Hey-Cunningham, A., Lehnert, W., Kench, P., Kassiou, M., Banati, R., Meikle, S. (2007), High-resolution imaging of the large non-human primate brain using microPET: a feasibility study. Physics in medicine and biology. 52(22), 6627-38. [Abstract]
  • Quinlivan, M., Chalon, S., Vergote, J., Henderson, J., Katsifis, A., Kassiou, M., Guilloteau, D. (2007), Decreased vesicular acetylcholine transporter and alpha(4)beta(2) nicotinic receptor density in the rat brain following 192 IgG-saporin immunolesioning. Neuroscience letters. 415(2), 97-101. [Abstract]
  • Liu, X., Banister, S., Christie, M., Banati, R., Meikle, S., Coster, M., Kassiou, M. (2007), Trishomocubanes: Novel sigma ligands modulate cocaine-induced behavioural effects. European journal of pharmacology. 555, 37-42. [Abstract]
  • Kassiou, M., Meikle, S., Cagnin, A., Banati, R. (2007), Positron emission tomography imaging of neuroinflammation. Neurotherapeutics. 4(3), 443-452. [Abstract]
  • Gunosewoyo, H., Coster, M., Kassiou, M. (2007), Molecular probes for P2X7 receptor studies. Current medicinal chemistry. 14(14), 1505-1523. [Abstract]
  • Collier, T., Waterhouse, R., Kassiou, M. (2007), Imaging sigma receptors: applications in drug development. Current pharmaceutical design. 13(1), 51-72. [Abstract]
  • Banister, S., Clegg, J., Coster, M., Jolliffe, K., Kassiou, M. (2007), (1R,2S,3R,6S,7R,8S)-Tricyclo[6.2.1.0(2,7)]-undeca-4,9-diene-3,6-diol. ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE. 63(Pt 1), O92-O93. [Abstract]
  • Roselt, P., Kassiou, M., Guilloteau, D., Fulham, M., Bodard, S., Eberl, S., Garreau, L., Chalon, S., Henderson, D., Fulton, R., Emond, P., Giboureau, N., Mavel, S. (2007), Ex vivo and in vivo evaluation of (2R,3R)-5-[F-18]-fluoroethoxy- and fluoropropoxy-benzovesamicol, as PET radioligands for the vesicular acetylcholine transporter. SYNAPSE. 61(12), 962-970. [Abstract]
  • Tavitian, B., Kassiou, M., Dolle, F., Hantraye, P., Trebossen, R., Gregoire, M., Thominiaux, C., Chauveau, F., Boutin, H., James, M. (2007), C-11-DPA-713: A novel peripheral benzodiazepine receptor PET ligand for in vivo imaging of neuroinflammation. JOURNAL OF NUCLEAR MEDICINE. 48(4), 573-581. [Abstract]

2006

  
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  • Assaad, T., Mavel, S., Parsons, S., Kruse, S., Galineau, L., Allouchi, H., Kassiou, M., Chalon, S., Guilloteau, D., Emond, P. (2006), Synthesis and in vitro evaluation of N-substituted aza-trozamicol analogs as vesicular acetylcholine transporter ligands. Bioorganic & Medicinal Chemistry Letters. 16(10), 2654-2657. [Abstract]
  • Thominiaux, C., Dolle, F., James, M., Bramoulle, Y., Boutin, H., Besret, L., Gregoire, M., Valette, H., Bottlaender, M., Tavitian, B., Hantraye, P., Selleri, S., Kassiou, M. (2006), Improved synthesis of the peripheral benzodiazepine receptor ligand C-11 DPA-713 using C-11 methyl triflate. Applied Radiation and Isotopes. 64(5), 570-573. [Abstract]
  • Truong, L., Allbutt, H., Kassiou, M., Henderson, J. (2006), Developing a preclinical model of Parkinson's disease: a study of behaviour in rats with graded 6-OHDA lesions. Behavioural brain research. 169(1), 1-9. [Abstract]
  • Thominiaux, C., de Bruin, B., Bramoulle, Y., Hinnen, F., Demphel, S., Valette, H., Bottlaender, M., Besret, L., Kassiou, M., Dolle, F. (2006), Radiosynthesis of (E)-N-(2- C-11 methoxybenzyl)-3-phenyl-acrylamidine, a novel subnanomolar NR2B subtype-selective NMDA receptor antagonist. Applied Radiation and Isotopes. 64(3), 348-354. [Abstract]
  • Vercouillie, J., Mavel, S., Galineau, L., Ragusa, T., Innis, R., Kassiou, M., Chalon, S., Dolle, F., Besnard, J., Guilloteau, D., Emond, P. (2006), Synthesis and in vitro evaluation of novel derivatives of diphenylsulfide as serotonin transporter ligands. Bioorganic & Medicinal Chemistry Letters. 16(5), 1297-1300. [Abstract]
  • Cagnin, A., Kassiou, M., Meikle, S., Banati, R. (2006), In vivo evidence for microglial activation in neuro degenerative dementia. Acta Neurologica Scandinavica. 114, 107-114. [Abstract]
  • Issa, F., Kassiou, M., Chan, H., McLeod, M. (2006), Synthesis and radiolabelling of ipratropium and tiotropium for use as PET ligands in the study of inhaled drug deposition. Australian Journal of Chemistry. 59(1), 53-58. [Abstract]
  • James, M., Selleri, S., Kassiou, M. (2006), Development of ligands for the peripheral benzodiazepine receptor. Current medicinal chemistry. 13(17), 1991-2001. [Abstract]