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Publications list for Associate Professor Michael Kassiou

2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003

2010

  
  • Banister, S., Moussa, I., Jordan, M., Coster, M., Kassiou, M. Oxo-bridged isomers of aza-trishomocubane sigma (sigma) receptor ligands: Synthesis, in vitro binding, and molecular modeling. Bioorganic & medicinal chemistry letters. 2010; 20:145-148. [Abstract]

2009

  
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  • Edington, A., McKinzie, A., Reynolds, A., Kassiou, M., Ryan, R., Vandenberg, R. Extracellular loops 2 and 4 of GLYT2 are required for N-arachidonyl-glycine inhibition of glycine transport. The Journal of biological chemistry. 2009; 284:36424-30. [Abstract]
  • Leaver, K., Allbutt, H., Creber, N., Kassiou, M., Henderson, J. Oral pre-treatment with epigallocatechin gallate in 6-OHDA lesioned rats produces subtle symptomatic relief but not neuroprotection. Brain Research Bulletin. 2009; 80:397-402. [Abstract]
  • Valette, H., Xiao, Y., Peyronneau, M., Damont, A., Kozikowski, A., Wei, Z., Kassiou, M., Kellar, K., Doll��, F., Bottlaender, M. 18F-ZW-104: A New Radioligand for Imaging Neuronal Nicotinic Acetylcholine Receptors--In Vitro Binding Properties and PET Studies in Baboons. Journal of nuclear medicine. 2009; 50:1349-1355. [Abstract]
  • Endres, C., Pomper, M., James, M., Uzuner, O., Hammoud, D., Watkins, C., Reynolds, A., Hilton, J., Dannals, R., Kassiou, M. Initial Evaluation of 11C-DPA-713, a Novel TSPO PET Ligand, in Humans. Journal of nuclear medicine. 2009; 50:1276-1282. [Abstract]
  • Gunosewoyo, H., Coster, M., Bennett, M., Kassiou, M. Purinergic P2X(7) receptor antagonists: Chemistry and fundamentals of biological screening. Bioorganic & medicinal chemistry. 2009; 17:4861-5. [Abstract]
  • Truong, L., Allbutt, H., Coster, M., Kassiou, M., Henderson, J. Behavioural effects of a selective NMDA NR1A/2B receptor antagonist in rats with unilateral 6-OHDA+parafascicular lesions. Brain research bulletin. 2009; 78:91-6. [Abstract]
  • Kassiou, M., Banati, R., Holsinger, R., Meikle, S. Challenges in molecular imaging of Parkinson's disease: A brief overview. Brain research bulletin. 2009; 78:105-8. [Abstract]
  • Warraich, S., Allbutt, H., Billing, R., Radford, J., Coster, M., Kassiou, M., Henderson, J. Evaluation of behavioural effects of a selective NMDA NR1A/2B receptor antagonist in the unilateral 6-OHDA lesion rat model. Brain research bulletin. 2009; 78:85-90. [Abstract]
  • Henderson, J., Lanciego, J., Smith, Y., Gundlach, A., Kassiou, M., , O. Proceedings of the 2007 International Brain Research Organisation Satellite Meeting "Movement Disorders: Focus on the Thalamus and Basal Ganglia" held in Sydney, Australia, 10-11 July, 2007. Brain research bulletin. 2009; 78:53-4. [Abstract]
  • Scarf, A., Ittner, L., Kassiou, M. The translocator protein (18 kDa): central nervous system disease and drug design. Journal of Medicinal Chemistry. 2009; 52:581-592. [Abstract]
  • Chauveau, F., Van Camp, N., Dolle, F., Kuhnast, B., Hinnen, F., Damont, A., Boutin, H., James, M., Kassiou, M., Tavitian, B. Comparative Evaluation of the Translocator Protein Radioligands C-11-DPA-713, F-18-DPA-714, and C-11-PK11195 in a Rat Model of Acute Neuroinflammation. Journal of Nuclear Medicine. 2009; 50:468-476. [Abstract]
  • Dollé, F., Luus, C., Reynolds, A., Kassiou, M. Radiolabelled Molecules for Imaging the Translocator Protein (18 kDa) Using Positron Emission Tomography. Current medicinal chemistry. 2009; 16:2899-2923. [Abstract]

2008

  
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  • Leaver, K., Allbutt, H., Creber, N., Kassiou, M., Henderson, J. NEUROPROTECTIVE EFFECTS OF A SELECTIVE N-METHYL-d-ASPARTATE NR2B RECEPTOR ANTAGONIST IN THE 6-HYDROXYDOPAMINE RAT MODEL OF PARKINSON'S DISEASE. Clinical and experimental pharmacology & physiology. 2008; 35:1388-94. [Abstract]
  • Gunosewoyo, H., Guo, J., Bennett, M., Coster, M., Kassiou, M. Cubyl amides: Novel P2X(7) receptor antagonists. Bioorganic & medicinal chemistry letters. 2008; 18:3720-3. [Abstract]
  • Besret, L., Dollé, F., Hérard, A., Guillermier, M., Demphel, S., Hinnen, F., Coulon, C., Ottaviani, M., Bottlaender, M., Hantraye, P., Kassiou, M. Dopamine D1 receptor imaging in the rodent and primate brain using the isoquinoline +-[11C]A-69024 and positron emission tomography. Journal of pharmaceutical sciences. 2008; 97:2811-2819. [Abstract]
  • van Dijk, A., Johnston, C., Allbutt, H., Kassiou, M., Henderson, J. Behavioural effects of trishomocubanes in rats with unilateral 6-hydroxydopamine lesions. Behavioural Brain Research. 2008; 190:14-21. [Abstract]
  • James, M., Fulton, R., Vercoullie, J., Henderson, D., Garreau, L., Chalon, S., Dolle, F., Selleri, S., Guilloteau, D., Kassiou, M. DPA-714, a New Translocator Protein-Specific Ligand: Synthesis, Radiofluorination, and Pharmacologic Characterization. Journal of nuclear medicine. 2008; 49:814-822. [Abstract]
  • Guenther, K., Hambley, T., Kassiou, M. Radiolabelled probes for imaging multidrug resistance using single photon emission tomography (SPECT) and positron emission tomography (PET). In: Multidrug Resistance: Biological and Pharmaceutical Advances in Antitumour Treatment. India: Research Signpost 2008. p. 291-320.
  • Damont, A., Hinnen, F., Kuhnast, B., Schollhorn-Peyronneau, M., James, M., Luus, C., Tavitian, B., Kassiou, M., Dolle, F. Radiosynthesis of [F-18]DPA-714, a selective radioligand for imaging the translocator protein (18 kDa) with PET. Journal of Labelled Compounds & Radiopharmaceuticals. 2008; 51:286-292. [Abstract]
  • Dollé, F., Langle, S., Roger, G., Fulton, R., Lagnel-de Bruin, B., Henderson, D., Hinnen, F., Paine, T., Coster, M., Valette, H., Bottlaender, M., Kassiou, M. Synthesis and In-Vivo Evaluation of [11C]p-PVP-MEMA as a PET Radioligand for Imaging Nicotinic Receptors. Australian Journal of Chemistry. 2008; 61:438–445.

2007

  
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  • Naidoo-Variawa, S., Hey-Cunningham, A., Lehnert, W., Kench, P., Kassiou, M., Banati, R., Meikle, S. High-resolution imaging of the large non-human primate brain using microPET: a feasibility study. Physics in medicine and biology. 2007; 52:6627-38. [Abstract]
  • Quinlivan, M., Chalon, S., Vergote, J., Henderson, J., Katsifis, A., Kassiou, M., Guilloteau, D. Decreased vesicular acetylcholine transporter and alpha(4)beta(2) nicotinic receptor density in the rat brain following 192 IgG-saporin immunolesioning. Neuroscience letters. 2007; 415:97-101. [Abstract]
  • Liu, X., Banister, S., Christie, M., Banati, R., Meikle, S., Coster, M., Kassiou, M. Trishomocubanes: Novel sigma ligands modulate cocaine-induced behavioural effects. European journal of pharmacology. 2007; 555:37-42. [Abstract]
  • Tavitian, B., Kassiou, M., Dolle, F., Hantraye, P., Trebossen, R., Gregoire, M., Thominiaux, C., Chauveau, F., Boutin, H., James, M. C-11-DPA-713: A novel peripheral benzodiazepine receptor PET ligand for in vivo imaging of neuroinflammation. JOURNAL OF NUCLEAR MEDICINE. 2007; 48:573-581. [Abstract]
  • Banister, S., Clegg, J., Coster, M., Jolliffe, K., Kassiou, M. (1R,2S,3R,6S,7R,8S)-Tricyclo[6.2.1.0(2,7)]-undeca-4,9-diene-3,6-diol. ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE. 2007; 63:O92-O93. [Abstract]
  • Roselt, P., Kassiou, M., Guilloteau, D., Fulham, M., Bodard, S., Eberl, S., Garreau, L., Chalon, S., Henderson, D., Fulton, R., Emond, P., Giboureau, N., Mavel, S. Ex vivo and in vivo evaluation of (2R,3R)-5-[F-18]-fluoroethoxy- and fluoropropoxy-benzovesamicol, as PET radioligands for the vesicular acetylcholine transporter. SYNAPSE. 2007; 61:962-970. [Abstract]
  • Kassiou, M., Meikle, S., Cagnin, A., Banati, R. Positron emission tomography imaging of neuroinflammation. Neurotherapeutics. 2007; 4:443-452. [Abstract]
  • Gunosewoyo, H., Coster, M., Kassiou, M. Molecular probes for P2X7 receptor studies. Current medicinal chemistry. 2007; 14:1505-1523. [Abstract]
  • Collier, T., Waterhouse, R., Kassiou, M. Imaging sigma receptors: applications in drug development. Current pharmaceutical design. 2007; 13:51-72. [Abstract]

2006

  
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  • Assaad, T., Mavel, S., Parsons, S., Kruse, S., Galineau, L., Allouchi, H., Kassiou, M., Chalon, S., Guilloteau, D., Emond, P. Synthesis and in vitro evaluation of N-substituted aza-trozamicol analogs as vesicular acetylcholine transporter ligands. Bioorganic & Medicinal Chemistry Letters. 2006; 16:2654-2657. [Abstract]
  • Thominiaux, C., Dolle, F., James, M., Bramoulle, Y., Boutin, H., Besret, L., Gregoire, M., Valette, H., Bottlaender, M., Tavitian, B., Hantraye, P., Selleri, S., Kassiou, M. Improved synthesis of the peripheral benzodiazepine receptor ligand C-11 DPA-713 using C-11 methyl triflate. Applied Radiation and Isotopes. 2006; 64:570-573. [Abstract]
  • Truong, L., Allbutt, H., Kassiou, M., Henderson, J. Developing a preclinical model of Parkinson's disease: a study of behaviour in rats with graded 6-OHDA lesions. Behavioural brain research. 2006; 169:1-9. [Abstract]
  • Thominiaux, C., de Bruin, B., Bramoulle, Y., Hinnen, F., Demphel, S., Valette, H., Bottlaender, M., Besret, L., Kassiou, M., Dolle, F. Radiosynthesis of (E)-N-(2- C-11 methoxybenzyl)-3-phenyl-acrylamidine, a novel subnanomolar NR2B subtype-selective NMDA receptor antagonist. Applied Radiation and Isotopes. 2006; 64:348-354. [Abstract]
  • Vercouillie, J., Mavel, S., Galineau, L., Ragusa, T., Innis, R., Kassiou, M., Chalon, S., Dolle, F., Besnard, J., Guilloteau, D., Emond, P. Synthesis and in vitro evaluation of novel derivatives of diphenylsulfide as serotonin transporter ligands. Bioorganic & Medicinal Chemistry Letters. 2006; 16:1297-1300. [Abstract]
  • James, M., Selleri, S., Kassiou, M. Development of ligands for the peripheral benzodiazepine receptor. Current medicinal chemistry. 2006; 13:1991-2001. [Abstract]
  • Cagnin, A., Kassiou, M., Meikle, S., Banati, R. In vivo evidence for microglial activation in neuro degenerative dementia. Acta Neurologica Scandinavica. 2006; 114:107-114. [Abstract]
  • Issa, F., Kassiou, M., Chan, H., McLeod, M. Synthesis and radiolabelling of ipratropium and tiotropium for use as PET ligands in the study of inhaled drug deposition. Australian Journal of Chemistry. 2006; 59:53-58. [Abstract]

2005

  
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  • Meikle, S., Kench, P., Kassiou, M., Banati, R. Small animal SPECT and its place in the matrix of molecular imaging technologies. Physics in medicine and biology. 2005; 50:R45-61. [Abstract]
  • James, M., Fulton, R., Henderson, D., Eberl, S., Meikle, S., Thomson, S., Allan, R., Dolle, F., Fulham, M., Kassiou, M. Synthesis and in vivo evaluation of a novel peripheral benzodiazepine receptor PET radioligand. Bioorganic & medicinal chemistry. 2005; 13:6188-94. [Abstract]
  • Kassiou, M., Dannals, R., Liu, X., Wong, D., Ravert, H., Scheffel, U. Synthesis and in vivo evaluation of a new PET radioligand for studying sigma-2 receptors. Bioorganic & medicinal chemistry. 2005; 13:3623-6. [Abstract]
  • Kassiou, M., Meikle, S., Banati, R. Ligands for peripheral benzodiazepine binding sites in glial cells. Brain research. Brain research reviews. 2005; 48:207-10. [Abstract]
  • Zea-Ponce, Y., Mavel, S., Assaad, T., Kruse, S., Parsons, S., Emond, P., Chalon, S., Giboureau, N., Kassiou, M., Guilloteau, D. Synthesis and in vitro evaluation of new benzovesamicol analogues as potential imaging probes for the vesicular acetylcholine transporter. Bioorganic & medicinal chemistry. 2005; 13:745-53. [Abstract]
  • Mohamed, A., Eberl, S., Fulham, M., Kassiou, M., Zaman, A., Henderson, D., Beveridge, S., Constable, C., Lo, S. Sequential I-123-iododexetimide scans in temporal lobe epilepsy: comparison with neuroimaging scans (MR imaging and F-18-FDG PET imaging). European Journal of Nuclear Medicine and Molecular Imaging. 2005; 32:180-185. [Abstract]
  • Kassiou, M. Capabilities of PET and SPECT in pre-clinical and clinical research. Current Pharmaceutical Design. 2005; 11:3201-3201. [Abstract]
  • James, M., Fulton, R., Henderson, D., Eberl, S., Fulham, M., Thomson, S., Allan, R., Dolle, F., Kassiou, M. Synthesis and In Vivo Evaluation of a Novel Peripheral Benzodiazepine Receptor PET Radioligand. UK: Wiley, 2005.
  • Kassiou, M., Pham, T., Fulton, R., Mattner, F., Henderson, D., Katsifis, A., Liu, X., Eberl, S., Greguric, I., Fulham, M., Thomson, S. Synthesis and in vivo evaluation of arylalkyl 4-benzyl piperidines as radioligands for sigma receptors. UK: Wiley, 2005.
  • Thominiaux, C., Bruin, B., Bramoulle, Y., Hinnen, F., Demphel, S., Bottlaender, M., Besret, L., Kassiou, M., Dolle, F. Radiosynthesis of (E)-N-(2-[11C]methoxybenzyl)-3-phenyl-acrylamidine, a novel subnanomolar NR2B subtype-selective NMDA receptor ligand. UK: Wiley, 2005.

2004

  
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  • Katsifis, A., Kassiou, M. Development of radioligands for in vivo imaging of GABA(A)-benzodiazepine receptors. Mini reviews in medicinal chemistry. 2004; 4:909-21. [Abstract]
  • Roger, G., Dollé, F., De Bruin, B., Liu, X., Besret, L., Bramoullé, Y., Coulon, C., Ottaviani, M., Bottlaender, M., Valette, H., Kassiou, M. Radiosynthesis and pharmacological evaluation of [11C]EMD-95885: a high affinity ligand for NR2B-containing NMDA receptors. Bioorganic & medicinal chemistry. 2004; 12:3229-37. [Abstract]
  • Henderson, D., Eberl, S., Thomson, S., Smith, A., Allan, R., Fulham, M., Loiacono, R., Kassiou, M. 3-Pyridyl ethers as SPECT radioligands for imaging nicotinic acetylcholine receptors. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine. 2004; 60:669-76. [Abstract]
  • Kassiou, M., Dolle, F., Valette, H., Demphel, S., Coulon, C., Ottaviani, M., Bottlaender, M. Radiosynthesis and in vivo evaluation of [11C]Ro-547312: a novel NR1/2B subtype selective NMDA receptor radioligand. Journal of Labelled Compounds and Radiopharmaceuticals. 2004; 47:911-920.
  • Roselt, P., Meikle, S., Kassiou, M. The role of positron emission tomography in the discovery and development of new drugs; as studied in laboratory animals. European journal of drug metabolism and pharmacokinetics. 2004; 29:1-6. [Abstract]

2003

  
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  • Quinlivan, M., Mattner, F., Papazian, V., Zhou, J., Katsifis, A., Emond, P., Chalon, S., Kozikowski, A., Guilloteau, D., Kassiou, M. Synthesis and evaluation of iodine-123 labelled tricyclic tropanes as radioligands for the serotonin transporter. Nuclear medicine and biology. 2003; 30:741-746. [Abstract]
  • Katsifis, A., Mardon, K., Mattner, F., Loc'h, C., McPhee, M., Dikic, B., Kassiou, M., Ridley, D. Pharmacological evaluation of (S)-8-[123I]iodobretazenil: a radioligand for in vivo studies of central benzodiazepine receptors. Nuclear medicine and biology. 2003; 30:191-198. [Abstract]
  • Roger, G., Lagnel, B., Besret, L., Bramoulle, Y., Coulon, C., Ottaviani, M., Kassiou, M., Bottlaender, M., Valette, H., Dolle, F. Synthesis, radiosynthesis and In Vivo evaluation of 5-[3-(4-Benzylpiperidin-1-yl) prop-1-ynyl]-1, 3-dihydrobenzoimidazol-2-[11C] one, as a potent NR 1A/2B subtype selective NMDA PET radiotracer. Bioorganic & Medicinal Chemistry. 2003; 11 (2003):5401-5408.
  • Wong, K., Elberl, S., Feng, D., Kassiou, M., Fulham, M. Quantification of 5-[123I]iodo-A-85380 in nonhuman primates using spect: parameter identifiability and stabilitty. UK: Pergamon, 2003.