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Associate Professor Simon Lewis

Associate Professor
Medicine, Central Clinical School

M02 - Mallet Street Campus
The University of Sydney
NSW 2006 Australia

T:+61 2 9351 0702
F:+61 2 9351 0855
E:

Biographical details

Dr Simon Lewis is an NHMRC Practitioner Fellow who works as a Consultant Neurologist at the Royal Prince Alfred Hospital and is Associate Professor in Cognitive Neuroscience at the University of Sydney. He is the Director of the Parkinson's Disease Research Clinic at the Brain & Mind Research Institute and heads the NSW Movement Disorders Brain Donor program. He has published over 50 peer review papers, 2 books and 2 book chapters and has attracted funding from the NHMRC, ARC and Michael J Fox Foundation to support his research interests targeting quality of life in PD. In addition to this research, he sits on the Council of Parkinson's NSW. He recently led the nationwide 'DASH to the InfoLine' campaign aiming to raise awareness and reduce stigma in PD and is now heading the first trial to evaluate community based Parkinson's nurse specialists in Australia.

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Current national competitive grants*

2011

Practitioner Fellowship 1
Lewis S
NHMRC Career Award: Practitioner Fellowship ($428,865 over 5 years)

2010

The impact of circadian disturbances on sleep quality, cognition and psychiatric symptoms in neurodegenerative disease
Lewis S, Naismith S, Rogers N, Hodges J
NHMRC Project Grant ($479,000 over 3 years)

* Grants administered through the University of Sydney

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Keywords

Neurosciences; Cognitive disorders; Neuroimaging; Parkinson's disease; Dementia

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International links

United States. (Mt Sinai, New York) A/Prof Steven Moore.

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Publications

2012 | 2011 | 2010 | 2009 | 2007 | 2006

2012

  
  • Shine, J., Moore, S., Bolitho, S., Morris, T., Dilda, V., Naismith, S., Lewis, S. Assessing the utility of Freezing of Gait Questionnaires in Parkinson's Disease. Parkinsonism & related disorders. 2012; 18:25-9. [Abstract]

2011

  
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  • Shine, J., Halliday, G., Naismith, S., Lewis, S. Visual misperceptions and hallucinations in Parkinson's disease: Dysfunction of attentional control networks?. Movement disorders : official journal of the Movement Disorder Society. 2011; 26:2154-9. [Abstract]
  • Shine, J., Naismith, S., Lewis, S. The pathophysiological mechanisms underlying freezing of gait in Parkinson's Disease. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. 2011; 18:1154-7. [Abstract]
  • Zhong, G., Naismith, S., Rogers, N., Lewis, S. Sleep-wake disturbances in common neurodegenerative diseases: A closer look at selected aspects of the neural circuitry. Journal of the neurological sciences. 2011; 307:9-14. [Abstract]
  • Abbott, L., Naismith, S., Lewis, S. Parkinson's disease in general practice: Assessing knowledge, confidence and the potential role of education. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. 2011; 18:1044-7. [Abstract]
  • Naismith, S., Rogers, N., Lewis, S., Terpening, Z., Ip, T., Diamond, K., Norrie, L., Hickie, I. Sleep disturbance relates to neuropsychological functioning in late-life depression. Journal of affective disorders. 2011; 132:139-45. [Abstract]
  • Naismith, S., Terpening, Z., Shine, J., Lewis, S. Neuropsychological functioning in Parkinson's disease: Differential relationships with self-reported sleep-wake disturbances. Movement disorders : official journal of the Movement Disorder Society. 2011; 26:1537-41. [Abstract]
  • Shine, J., Ward, P., Naismith, S., Pearson, M., Lewis, S. Utilising functional MRI (fMRI) to explore the freezing phenomenon in Parkinson's disease. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. 2011; 18:807-10. [Abstract]
  • Lewis, S. Commentary: An evaluation of mechanisms underlying the influence of step cues on gait in Parkinson's disease. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. 2011; 18:803. [Abstract]
  • Hardy, T., Garsia, R., Halmagyi, G., Lewis, S., Harrisberg, B., Fulham, M., Barnett, M. Tumour necrosis factor (TNF) inhibitor therapy in Susac's syndrome. Journal of the neurological sciences. 2011; 302:126-8. [Abstract]
  • Naismith, S., Lewis, S. "DASH" symptoms in patients with Parkinson's disease: red flags for early cognitive decline. Journal of Clinical Neuroscience. 2011; 18:352-355. [Abstract]
  • Naismith, S., Diamond, K., Carter, P., Norrie, L., Redoblado-Hodge, M., Lewis, S., Hickie, I. Enhancing Memory in Late-Life Depression: The Effects of a Combined Psychoeducation and Cognitive Training Program. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. 2011; 19:240-8. [Abstract]
  • Naismith, S., Lewis, S., Rogers, N. Sleep-wake changes and cognition in neurodegenerative disease. Progress in Brain Research. 2011; 190:21-52. [Abstract]
  • Hurelbrink, C., Lewis, S. Pathological considerations in the treatment of Parkinson's disease: More than just a wiring diagram. Clinical neurology and neurosurgery. 2011; 113:1-6. [Abstract]
  • Naismith, S., Pereira, M., Shine, J., Lewis, S. How well do caregivers detect mild cognitive change in Parkinson's disease?. Movement disorders : official journal of the Movement Disorder Society. 2011; 26:161-4. [Abstract]
  • Komadina, N., Terpening, Z., Huang, Y., Halliday, G., Naismith, S., Lewis, S. Utility and Limitations of Addenbrooke's Cognitive Examination-Revised for Detecting Mild Cognitive Impairment in Parkinson's Disease. Dementia and geriatric cognitive disorders. 2011; 31:349-57. [Abstract]

2010

  
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  • Naismith, S., Lewis, S. A novel paradigm for modelling freezing of gait in Parkinson's disease. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. 2010; 17:984-7. [Abstract]
  • Naismith, S., Shine, J., Lewis, S. The specific contributions of set-shifting to freezing of gait in Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society. 2010; 25:1000-4. [Abstract]
  • Gunn, D., Naismith, S., Lewis, S. Sleep disturbances in Parkinson disease and their potential role in heterogeneity. Journal of Geriatric Psychiatry and Neurology. 2010; 23:131-7. [Abstract]
  • Naismith, S., Rogers, N., Hickie, I., Mackenzie, J., Norrie, L., Lewis, S. Sleep Well, Think Well: Sleep-Wake Disturbance in Mild Cognitive Impairment. Journal of geriatric psychiatry and neurology. 2010; 23:123-30. [Abstract]
  • Naismith, S., Rogers, N., Mackenzie, J., Hickie, I., Lewis, S. The relationship between actigraphically defined sleep disturbance and REM sleep behaviour disorder in Parkinson's Disease. Clinical neurology and neurosurgery. 2010; 112:420-3. [Abstract]
  • Naismith, S., Redoblado-Hodge, M., Lewis, S., Scott, E., Hickie, I. Cognitive training in affective disorders improves memory: A preliminary study using the NEAR approach. Journal of affective disorders. 2010; 121:258-62. [Abstract]
  • Ahmed, R., Green, T., Halmagyi, G., Lewis, S. A new model for neurology care in the emergency department. The Medical Journal of Australia. 2010; 192:30-32. [Abstract]
  • Naismith, S., Hickie, I., Lewis, S. The role of mild depression in sleep disturbance and quality of life in Parkinson's disease. The Journal of Neuropsychiatry and Clinical Neurosciences. 2010; 22:384-389. [Abstract]
  • Lewis, S., Naismith, S. DASH to the InfoLine: Promoting a healthy brain and mind in Parkinson’s Disease. Australia: LifeBlood, 2010.

2009

  
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  • Parratt, K., Allan, M., Lewis, S., Dalmau, J., Halmagyi, G., Spies, J. Acute psychiatric illness in a young woman: an unusual form of encephalitis. The Medical Journal of Australia. 2009; 191:284-286. [Abstract]
  • Naismith, S., Norrie, L., Lewis, S., Rogers, N., Scott, E., Hickie, I. Does sleep disturbance mediate neuropsychological functioning in older people with depression?. Journal of Affective Disorders. 2009; 116:139-143. [Abstract]
  • Lewis, S., Barker, R. A pathophysiological model of freezing of gait in Parkinson's disease. Parkinsonism & related disorders. 2009; 15:333-8. [Abstract]
  • Lewis, S., Barker, R. Understanding the dopaminergic deficits in Parkinson's disease: insights into disease heterogeneity. Journal of clinical neuroscience. 2009; 16:620-625. [Abstract]
  • Clatworthy, P., Lewis, S., Brichard, L., Hong, Y., Izquierdo, D., Clark, L., Cools, R., Aigbirhio, F., Baron, J., Fryer, T., Robbins, T. Dopamine release in dissociable striatal subregions predicts the different effects of oral methylphenidate on reversal learning and spatial working memory. The Journal of Neuroscience. 2009; 29:4690-4696. [Abstract]
  • Lewis, S. Parkinson’s Disease: New approaches to treatment, non-drug management, and how to monitor response or side effects of medications. Geriatric Medicine in General Practice. 2009; 1:18-20.
  • Alkhalil, M., Lewis, S., Hawker, M., Dick, D. Persistent unilateral mydriasis and headache. BMJ case reports. 2009; 2009:bcr11.2008.1260. [Abstract]
  • Lewis, S. Parkinson's Disease: New approaches to treatment, non-drug management, and how to monitor response or side effects of medications. Geriatric Medicine in General Practice. 2009; 1:18-20.

2007

  
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  • Stacpoole, S., McGuigan, C., Lewis, S., Phadke, R., Stevens, J., Choi, D., Kapoor, R. Spinal claudication due to myxopapillary ependymoma. Practical Neurology. 2007; 7:394-396. [Abstract]
  • Goris, A., Williams-Gray, C., Clark, G., Foltynie, T., Lewis, S., Brown, J., Ban, M., Spillantini, M., Compston, A., Burn, D., Chinnery, P., Barker, R., Sawcer, S. Tau and alpha-synuclein in susceptibility to, and dementia in, Parkinson's disease. Annals of neurology. 2007; 62:145-153. [Abstract]
  • Cools, R., Lewis, S., Clark, L., Barker, R., Robbins, T. L-DOPA disrupts activity in the nucleus accumbens during reversal learning in Parkinson's disease. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2007; 32:180-189. [Abstract]

2006

  
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  • Michell, A., Xu, Z., Fritz, D., Lewis, S., Foltynie, T., Williams-Gray, C., Robbins, T., Carpenter, R., Barker, R. Saccadic latency distributions in Parkinson's disease and the effects of L-dopa. Experimental Brain Research. 2006; 174:7-18. [Abstract]
  • Slabosz, A., Lewis, S., Smigasiewicz, K., Szymura, B., Barker, R., Owen, A. The role of learned irrelevance in attentional set-shifting impairments in Parkinson's disease. Neuropsychology. 2006; 20:578-588. [Abstract]
  • Brown, J., Lewis, S. The use of rasagiline in conjunction with levodopa in Parkinson’s disease. British Journal of Neuroscience Nursing. 2006; 2:404-409.
  • Williams-Gray, C., Foltynie, T., Lewis, S., Barker, R. Cognitive deficits and psychosis in Parkinson's disease: a review of pathophysiology and therapeutic options. CNS drugs. 2006; 20:477-505. [Abstract]