Professor Thomas Becker

Chair of Developmental Neurobiology
Brain & Mind Research Institute, Sydney Medical School

M02 - Mallet Street Campus
The University of Sydney
NSW 2006 Australia

T:+61 2 9351 0997
E:

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Themes | Grants | Keywords | Publications

 

Current national competitive grants*

2012

In vivo analysis of miRNAs associated with neurological diseases
Becker T, Rinkwitz S, Cairns M
NHMRC Project Grants ($573,660 over 3 years)

2011

Identification of genes for X-linked mental retardation
Gecz J, Ropers H, Becker T, Haan E
National Health and Medical Research Council/ Project Grants ($114,000 over 3 years)

Cis regulatory and functional analysis of genomic loci with implication in hypothalamic obesity using the zebrafish as a model system
Rinkwitz S, Becker T
National Health and Medical Research Council Project Grant ($465,022 over 3 years)

2010

Zebrafish regulomics for human health - ZF-HEALTH
Geisler R, Becker T
European Commission (Belgium) Seventh Framework Network of Excellence Programme ($301,705 over 4 years)

Zebrafish Regulomics for Human Health
Becker T, Geisler R
National Health and Medical Research Council Strategic Award: Australian-European Union Health Research Grant ($621,250 over 5 years)

* Grants administered through the University of Sydney

Keywords

Cognitive disorders; Genetic diseases

Publications

2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007

2013

  
  • Svahn, A., Graeber, M., Ellett, F., Lieschke, G., Rinkwitz, S., Bennett, M., Becker, T. (2013), Development of ramified microglia from early macrophages in the zebrafish optic tectum. Developmental Neurobiology. 73(1), 60-71. [Abstract]

2012

  
  • Coolen, M., Thieffry, D., Drivenes, O., Becker, T., Bally-Cuif, L. (2012), miR-9 Controls the Timing of Neurogenesis through the Direct Inhibition of Antagonistic Factors. Developmental Cell. 22(5), 1052-1064. [Abstract]
  • Becker, T., Rinkwitz, S. (2012), Zebrafish as a genomics model for human neurological and polygenic disorders. Developmental Neurobiology. 72(3), 415-428. [Abstract]
  • Sundström, E., Komisarczuk, A., Jiang, L., Golovko, A., Navratilova, P., Rinkwitz, S., Becker, T., Andersson, L. (2012), Identification of a melanocyte-specific, MITF-dependent regulatory element in the intronic duplication causing hair greying and melanoma in horses. Pigment Cell & Melanoma Research. 25(1), 28-36. [Abstract]
  • Folgueira, M., Bayley, P., Navratilova, P., Becker, T., Wilson, S., Clarke, J. (2012), Morphogenesis underlying the development of the everted teleost telencephalon. Neural Development. 7, 32. [Abstract]

2011

  
  • Rinkwitz, S., Mourrain, P., Becker, T. (2011), Zebrafish: an integrative System for Neurogenomics and Neurosciences. Progress in neurobiology. 93(2), 231-43. [Abstract]
  • Labalette, C., Bouchoucha, Y., Wassef, M., Gongal, P., Le Men, J., Becker, T., Gilardi-Hebenstreit, P., Charnay, P. (2011), Hindbrain patterning requires fine-tuning of early krox20 transcription by Sprouty 4. Development. 138(2), 317-326. [Abstract]

2010

  
  • Punnamoottil, B., Herrmann, C., Pascual-Anaya, J., D'Aniello, S., Garcia-Fernàndez, J., Akalin, A., Becker, T., Rinkwitz, S. (2010), Cis-regulatory characterization of sequence conservation surrounding the Hox4 genes. Developmental biology. 340(2), 269-282. [Abstract]
  • Dong, X., Navratilova, P., Fredman, D., Drivenes, O., Becker, T., Lenhard, B. (2010), Exonic remnants of whole-genome duplication reveal cis-regulatory function of coding exons. Nucleic acids research. 38(4), 1071-85. [Abstract]
  • Navratilova, P., Fredman, D., Lenhard, B., Becker, T. (2010), Regulatory divergence of the duplicated chromosomal loci sox11a/b by subpartitioning and sequence evolution of enhancers in zebrafish. Molecular Genetics and Genomics. 283(2), 171-84. [Abstract]
  • Ragvin, A., Moro, E., Fredman, D., Navratilova, P., Drivenes, Ã., Engström, P., Alonso, M., de la Calle Mustienes, E., Gómez Skarmeta, J., Tavares, M., Casares, F., Manzanares, M., van Heyningen, V., Molven, A., Njølstad, P., Argenton, F., Lenhard, B., Becker, T. (2010), Long-range gene regulation links genomic type 2 diabetes and obesity risk regions to HHEX, SOX4, and IRX3. National Academy of Sciences Proceedings. 107(2), 775-780. [Abstract]

2009

  
  • Komisarczuk, A., Kawakami, K., Becker, T. (2009), Cis-regulation and chromosomal rearrangement of the fgf8 locus after the teleost/tetrapod split. Developmental Biology. 336(2), 301-312. [Abstract]
  • Navratilova, P., Becker, T. (2009), Genomic regulatory blocks in vertebrates and implications in human disease. Briefings in functional genomics & proteomics. 8(0), 333-42. [Abstract]
  • Amsterdam, A., Lai, K., Komisarczuk, A., Becker, T., Bronson, R., Hopkins, N., Lees, J. (2009), Zebrafish Hagoromo mutants up-regulate fgf8 postembryonically and develop neuroblastoma. Molecular Cancer Research. 7(6), 841-850. [Abstract]
  • Navratilova, P., Fredman, D., Hawkins, T., Turner, K., Lenhard, B., Becker, T. (2009), Systematic human/zebrafish comparative identification of cis-regulatory activity around vertebrate developmental transcription factor genes. Developmental biology. 327(2), 526-540. [Abstract]

2008

  
  • Topp, S., Stigloher, C., Komisarczuk, A., Adolf, B., Becker, T., Bally-Cuif, L. (2008), Fgf signaling in the zebrafish adult brain: association of Fgf activity with ventricular zones but not cell proliferation. The Journal of Comparative Neurology. 510(4), 422-439. [Abstract]
  • Komisarczuk, A., Topp, S., Stigloher, C., Kapsimali, M., Bally-Cuif, L., Becker, T. (2008), Enhancer detection and developmental expression of zebrafish sprouty1, a member of the fgf8 synexpression group. Developmental Dynamics. 237(9), 2594-2603. [Abstract]
  • Punnamoottil, B., Kikuta, H., Pezeron, G., Erceg, J., Becker, T., Rinkwitz, S. (2008), Enhancer detection in zebrafish permits the identification of neuronal subtypes that express Hox4 paralogs. Developmental Dynamics. 237(8), 2195-2208. [Abstract]
  • Hoppmann, V., Wu, J., Søviknes, A., Helvik, J., Becker, T. (2008), Expression of the eight AMPA receptor subunit genes in the developing central nervous system and sensory organs of zebrafish. Developmental Dynamics. 237(3), 788-799. [Abstract]
  • Bessa, J., Tavares, M., Santos, J., Kikuta, H., Laplante, M., Becker, T., Gómez-Skarmeta, J., Casares, F. (2008), meis1 regulates cyclin D1 and c-myc expression, and controls the proliferation of the multipotent cells in the early developing zebrafish eye. Development. 135(5), 799-803. [Abstract]
  • Pézeron, G., Mourrain, P., Courty, S., Ghislain, J., Becker, T., Rosa, F., David, N. (2008), Live analysis of endodermal layer formation identifies random walk as a novel gastrulation movement. Current Biology. 18(4), 276-281. [Abstract]
  • Meijer, A., van der Sar, A., Cunha, C., Lamers, G., Laplante, M., Kikuta, H., Bitter, W., Becker, T., Spaink, H. (2008), Identification and real-time imaging of a myc-expressing neutrophil population involved in inflammation and mycobacterial granuloma formation in zebrafish. Developmental and Comparative Immunology. 32(1), 36-49. [Abstract]

2007

  
  • Weiner, A., Allende, M., Becker, T., Calcaterra, N. (2007), CNBP mediates neural crest cell expansion by controlling cell proliferation and cell survival during rostral head development. Journal of cellular biochemistry. 102(6), 1553-1570. [Abstract]
  • Engström, P., Ho Sui, S., Drivenes, O., Becker, T., Lenhard, B. (2007), Genomic regulatory blocks underlie extensive microsynteny conservation in insects. Genome Research. 17(12), 1898-908. [Abstract]
  • Becker, T., Lenhard, B. (2007), The random versus fragile breakage models of chromosome evolution: a matter of resolution. Molecular Genetics and Genomics. 278(5), 487-491. [Abstract]
  • Herpin, A., Lelong, C., Becker, T., Favrel, P., Cunningham, C. (2007), A tolloid homologue from the Pacific oyster Crassostrea gigas. Gene expression patterns. 7(6), 700-708. [Abstract]
  • Kikuta, H., Laplante, M., Navratilova, P., Komisarczuk, A., Engström, P., Fredman, D., Akalin, A., Caccamo, M., Sealy, I., Howe, K., Ghislain, J., Pezeron, G., Mourrain, P., Ellingsen, S., Oates, A., Thisse, C., Thisse, B., Foucher, I., Adolf, B., Geling, A., Lenhard, B., Becker, T. (2007), Genomic regulatory blocks encompass multiple neighboring genes and maintain conserved synteny in vertebrates. Genome research. 17(5), 545-555. [Abstract]
  • Shankaran, S., Sieger, D., Schröter, C., Czepe, C., Pauly, M., Laplante, M., Becker, T., Oates, A., Gajewski, M. (2007), Completing the set of h/E(spl) cyclic genes in zebrafish: her12 and her15 reveal novel modes of expression and contribute to the segmentation clock. Developmental biology. 304(2), 615-632. [Abstract]
  • Kikuta, H., Fredman, D., Rinkwitz, S., Lenhard, B., Becker, T. (2007), Retroviral enhancer detection insertions in zebrafish combined with comparative genomics reveal genomic regulatory blocks - a fundamental feature of vertebrate genomes. Genome biology. 8 Suppl 1, S4. [Abstract]