Ongoing projects led by Professor Ian Hickie and the Youth Mental Health Program are shedding new light on personalised and effective early intervention for mental health conditions such as bipolar disorder.

Associate Professor Jim Lagopoulos and his Advanced Multimodal Imaging team supports many of the MRI studies into bipolar disorder.

We are also studying the impact of sleep and the biological (circadian) clock on bipolar and other mood disorders and cognitive performance in the Chronobiology and Sleep Program.

In the laboratory, researchers in our Imaging Physics Program are developing technologies enabling scientists to test new drugs and interventions for a wide variety of brain disorders, including bipolar disorder.

Researchers in the Drug Discovery Research Program, led by Professor Michael Kassiou, are working to better understand the action of both novel and existing therapeutic molecules. A key focus of their research is the translocator protein TSPO, which is present in the brain in higher quantities when there is illness or trauma. The researchers are investigating molecules that bind to TSPO (called TSPO ligands) that may have a therapeutic effect on diseases of the central nervous system, which include psychoses, mood disorders, neurological diseases like multiple sclerosis, and cancers of the brain.

Clinical studies

Research on Juvenile Bipolar Disorder

If you are between the ages of 12 and 18, and either have been diagnosed with bipolar disorder or alternatively would like to be a control and do not have any significant medical history we’d love to hear from you. Find out more...

Useful links

Especially for young people