Professor Anna deFazio

Sydney West Chair in Translational Cancer Research
Obstetrics, Gynaecology and Neonatology, Westmead Clinical School
Westmead Millennium Institute for Medical Research

C24 - Westmead Hospital
The University of Sydney
NSW 2006 Australia

T: +61 2 9845 7376
E:

W: Related website

Publications

2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008

2014

   
  • Dixon, S., Ibiebele, T., Protani, M., Beesley, J., Defazio, A., Crandon, A., Gard, G., Rome, R., Webb, P., Nagle, C. (2014), Dietary folate and related micronutrients, folate-metabolising genes, and ovarian cancer survival. Gynecologic Oncology. 132(3), 566-572. [Abstract]
  • Au-Yeung, G., Webb, P., DeFazio, A., Fereday, S., Bressel, M., Mileshkin, L. (2014), Impact of obesity on chemotherapy dosing for women with advanced stage serous ovarian cancer in the Australian Ovarian Cancer Study (AOCS). Gynecologic Oncology. 133(1), 16-22. [Abstract]
  • Butow, P., Price, M., Bell, M., Webb, P., deFazio, A., Friedlander, M. (2014), Caring for women with ovarian cancer in the last year of life: a longitudinal study of caregiver quality of life, distress and unmet needs. Gynecologic Oncology. 132(3), 690-697. [Abstract]
  • Beesley, V., Green, A., Wyld, D., O'Rourke, P., Wockner, L., deFazio, A., Butow, P., Price, M., Horwood, K., Clavarino, A., Australian Ovarian Cancer Study Group, Z., Australian Ovarian Cancer Study-Quality Of Life Study Investigators, Z., Webb, P. (2014), Quality of life and treatment response among women with platinum-resistant versus platinum-sensitive ovarian cancer treated for progression: a prospective analysis. Gynecologic Oncology. 132(1), 130-136. [Abstract]
  • Gao, B., Russell, A., Beesley, J., Chen, X., Healey, S., Henderson, M., Wong, M., Emmanuel, C., Galletta, L., Johnatty, S., Bowtell, D., Haber, M., Norris, M., Harnett, P., Chenevix-Trench, G., Balleine, R., Defazio, A. (2014), Paclitaxel sensitivity in relation to ABCB1 expression, efflux and single nucleotide polymorphisms in ovarian cancer. Scientific Reports. 4, 4669. [Abstract]

2013

   
  • Johnatty, S., Beesley, J., Gao, B., Chen, X., Lu, Y., Law, M., Henderson, M., Russell, A., Hedditch, E., Emmanuel, C., Fereday, S., Webb, P., Goode, E., Vierkant, R., Fridley, B., Cunningham, J., Fasching, P., Beckmann, M., Ekici, A., Hogdall, E., Kjaer, S., Jensen, A., Hogdall, C., Brown, R., Paul, J., Lambrechts, S., Despierre, E., Vergote, I., Lester, J., Karlan, B., Heitz, F., du Bois, A., Harter, P., Schwaab, I., Bean, Y., Pejovic, T., Levine, D., Goodman, M., Camey, M., Thompson, P., Lurie, G., Shildkraut, J., Berchuck, A., Terry, K., Cramer, D., Norris, M., Haber, M., MacGregor, S., deFazio, A., Chenevix-Trench, G. (2013), ABCB1 (MDR1) polymorphisms and ovarian cancer progression and survival: a comprehensive analysis from the Ovarian Cancer Association Consortium and The Cancer Genome Atlas. Gynecologic Oncology. 131(1), 8-14. [Abstract]
  • Sieh, W., Kobel, M., Longacre, T., Bowtell, D., deFazio, A., Goodman, M., Hogdall, E., Deen, S., Wentzensen, N., Moysich, K., Brenton, J., Clarke, B., Menon, U., Gilks, C., Kim, A., Madore, J., Fereday, S., George, J., Galletta, L., Lurie, G., Wilkens, L., Carney, M., Thompson, P., Matsuno, R., Kjaer, S., Jensen, A., Hogdall, C., Kalli, K., Fridley, B., Keeney, G., Vierkant, R., Cunningham, J., Brinton, L., Yang, H., Sherman, M., Garcia-Closas, M., Lissowska, J., Odunsi, K., Morrison, C., Lele, S., Bshara, W., Sucheston, L., Jimenez-Linan, M., Driver, K., Alsop, J., Mack, M., McGuire, V., Rothstein, J., Rosen, B., Bernardini, M., Mackay, H., Oza, A., Wozniak, E., Benjamin, E., Gentry-Maharaj, A., Gayther, S., Tinker, A., Prentice, L., Chow, C., Anglesio, M., Johnatty, S., Chenevix-Trench, G., Whittemore, A., Pharoah, P., Goode, E., Huntsman, D., Ramus, S. (2013), Hormone-receptor expression and ovarian cancer survival: an Ovarian Tumor Tissue Analysis consortium study. Lancet Oncology. 14(9), 853-862. [Abstract]
  • George, J., Alsop, K., Etemadmoghadam, D., Hondow, H., Mikeska, T., Dobrovic, A., Defazio, A., Smyth, G., Levine, D., Mitchell, G., Bowtell, D. (2013), Nonequivalent Gene Expression and Copy Number Alterations in High-Grade Serous Ovarian Cancers with BRCA1 and BRCA2 Mutations. Clinical Cancer Research. 19(13), 3474-3484. [Abstract]
  • White, K., Vierkant, R., Fogarty, Z., Charbonneau, B., Block, M., Pharoah, P., Chenevix-Trench, G., Rossing, M., Cramer, D., Pearce, C., Schildkraut, J., Menon, U., Kjaer, S., Levine, D., Gronwald, J., Culver, H., Whittemore, A., Karlan, B., Lambrechts, D., Wentzensen, N., Kupryjanczyk, J., Chang-Claude, J., Bandera, E., Hogdall, E., Heitz, F., Kaye, S., Fasching, P., Campbell, I., Goodman, M., Pejovic, T., Bean, Y., Lurie, G., Eccles, D., Hein, A., Beckmann, M., Ekici, A., Paul, J., Brown, R., Flanagan, J., Harter, P., du Bois, A., Schwaab, I., Hogdall, C., Lundvall, L., Olson, S., Orlow, I., Paddock, L., Rudolph, A., Eilber, U., Dansonka-Mieszkowska, A., Rzepecka, I., Ziolkowska-Seta, I., Brinton, L., Yang, H., Garcia-Closas, M., Despierre, E., Lambrechts, S., Vergote, I., Walsh, C., Lester, J., Sieh, W., McGuire, V., Rothstein, J., Ziogas, A., Lubinski, J., Cybulski, C., Menkiszak, J., Jensen, A., Gayther, S., Ramus, S., Gentry-Maharaj, A., Berchuck, A., Wu, A., Pike, M., Van Denberg, D., Terry, K., Vitonis, A., Doherty, J., Johnatty, S., Defazio, A., Song, H., Tyrer, J., Sellers, T., Phelan, C., Kalli, K., Cunningham, J., Fridley, B., Goode, E. (2013), Analysis of over 10,000 Cases finds no association between previously reported candidate polymorphisms and ovarian cancer outcome. Cancer Epidemiology, Biomarkers & Prevention. 22(5), 987-992. [Abstract]
  • Jordan, S., Steer, C., DeFazio, A., Quinn, M., Obermair, A., Friedlander, M., Francis, J., O'Brien, S., Goss, G., Wyld, D., Australian Ovarian Cancer Study Group, Z., Webb, P. (2013), Patterns of chemotherapy treatment for women with invasive epithelial ovarian cancer--a population-based study. Gynecologic Oncology. 129(2), 310-317. [Abstract]
  • Price, M., Bell, M., Sommeijer, D., Friedlander, M., Stockler, M., Defazio, A., Webb, P., Butow, P. (2013), Physical symptoms, coping styles and quality of life in recurrent ovarian cancer: A prospective population-based study over the last year of life. Gynecologic Oncology. 130(1), 162-168. [Abstract]
  • Verhaak, R., Tamayo, P., Yang, J., Hubbard, D., Zhang, H., Creighton, C., Fereday, S., Lawrence, M., Carter, S., Mermel, C., Kostic, A., Etemadmoghadam, D., Saksena, G., Cibulskis, K., Duraisamy, S., Levanon, K., Sougnez, C., Tsherniak, A., Gomez, S., Onofrio, R., Gabriel, S., Chin, L., Zhang, N., Spellman, P., Zhang, Y., Akbani, R., Hoadley, K., Kahn, A., Kobel, M., Huntsman, D., Soslow, R., Defazio, A., Birrer, M., Gray, J., Weinstein, J., Bowtell, D., Drapkin, R., Mesirov, J., Getz, G., Levine, D., Meyerson, M. (2013), Prognostically relevant gene signatures of high-grade serous ovarian carcinoma. The Journal of clinical investigation. 123(1), 517-525. [Abstract]
  • Baumbusch, L., Helland, √., Wang, Y., Liestol, K., Schaner, M., Holm, R., Etemadmoghadam, D., Alsop, K., Brown, P., Mitchell, G., Fereday, S., DeFazio, A., Bowtell, D., Kristensen, G., Lingjaerde, O., Borresen-Dale, A. (2013), High levels of genomic aberrations in serous ovarian cancers are associated with better survival. PloS One. 8(1), e54356. [Abstract]

2012

   
  • Lu, Y., Chen, X., Beesley, J., Johnatty, S., Defazio, A., Lambrechts, S., Lambrechts, D., Despierre, E., Vergotes, I., Chang-Claude, J., Hein, R., Nickels, S., Wang-Gohrke, S., D√ɬ∂rk, T., D√ɬľrst, M., Antonenkova, N., Bogdanova, N., Goodman, M., Lurie, G., Wilkens, L., Carney, M., Butzow, R., Nevanlinna, H., Heikkinen, T., Leminen, A., Kiemeney, L., Massuger, L., van Altena, A., Aben, K., Kjaer, S., H√ɬłgdall, E., Jensen, A., Brooks-Wilson, A., Le, N., Cook, L., Earp, M., Kelemen, L., Easton, D., Pharoah, P., Song, H., Tyrer, J., Ramus, S., Menon, U., Gentry-Maharaj, A., Gayther, S., Bandera, E., Olson, S., Orlow, I., Rodriguez-Rodriguez, L., Macgregor, S., Chenevix-Trench, G. (2012), Genome-wide association study for ovarian cancer susceptibility using pooled DNA. Twin Research and Human Genetics. 15(5), 615-623. [Abstract]
  • Wang, Z., Birkbak, N., Culhane, A., Drapkin, R., Fatima, A., Tian, R., Schwede, M., Alsop, K., Daniels, K., Piao, H., Liu, J., Etemadmoghadam, D., Miron, A., Salvesen, H., Mitchell, G., Defazio, A., Quackenbush, J., Berkowitz, R., Iglehart, J., Bowtell, D., Matulonis, U. (2012), Profiles of Genomic Instability in High-Grade Serous Ovarian Cancer Predict Treatment Outcome. Clinical Cancer Research. 18(20), 5806-5815. [Abstract]
  • Cowin, P., George, J., Fereday, S., Loehrer, E., Van Loo, P., Cullinane, C., Etemadmoghadam, D., Ftouni, S., Galletta, L., Anglesio, M., Hendley, J., Bowes, L., Sheppard, K., Christie, E., Pearson, R., Harnett, P., Heinzelmann-Schwarz, V., Friedlander, M., McNally, O., Quinn, M., Campbell, P., Defazio, A., Bowtell, D. (2012), LRP1B Deletion in High-Grade Serous Ovarian Cancers Is Associated with Acquired Chemotherapy Resistance to Liposomal Doxorubicin. Cancer Research. 72(16), 4060-4073. [Abstract]
  • Alsop, K., Fereday, S., Meldrum, C., Defazio, A., Emmanuel, C., George, J., Dobrovic, A., Birrer, M., Webb, P., Stewart, C., Friedlander, M., Fox, S., Bowtell, D., Mitchell, G. (2012), BRCA Mutation Frequency and Patterns of Treatment Response in BRCA Mutation-Positive Women With Ovarian Cancer: A Report From the Australian Ovarian Cancer Study Group. Journal of Clinical Oncology. 30(21), 2654-2663. [Abstract]

2011

   
  • Hunter, S., Anglesio, M., Sharma, R., Gilks, C., Melnyk, N., Chiew, Y., Defazio, A., Longacre, T., Huntsman, D., Gorringe, K., Campbell, I. (2011), Copy Number Aberrations in Benign Serous Ovarian Tumors: A Case for Reclassification?. Clinical Cancer Research. 17(23), 7273-7282. [Abstract]
  • Huang, R., Johnatty, S., Gamazon, E., Im, H., Ziliak, D., Duan, S., Zhang, W., Kistner, E., Chen, P., Beesley, J., Mi, S., O'Donnell, P., Fraiman, Y., Das, S., Cox, N., Lu, Y., Macgregor, S., Goode, E., Vierkant, R., Fridley, B., Hogdall, E., Kjaer, S., Jensen, A., Moysich, K., Grasela, M., Odunsi, K., Brown, R., Paul, J., Lambrechts, D., Despierre, E., Vergote, I., Gross, J., Karlan, B., Defazio, A., Chenevix-Trench, G., Dolan, M. (2011), Platinum Sensitivity-Related Germline Polymorphism Discovered via a Cell-Based Approach and Analysis of Its Association with Outcome in Ovarian Cancer Patients. Clinical cancer research : an official journal of the American Association for Cancer Research. 17(16), 5490-500. [Abstract]
  • Nagle, C., Francis, J., Nelson, A., Zorbas, H., Luxford, K., de Fazio, A., Fereday, S., Bowtell, D., Green, A., Webb, P. (2011), Reducing Time to Diagnosis Does Not Improve Outcomes for Women With Symptomatic Ovarian Cancer: A Report From the Australian Ovarian Cancer Study Group. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 29(16), 2253-8. [Abstract]
  • Pharoah, P., Palmieri, R., Ramus, S., Gayther, S., Andrulis, I., Anton-Culver, H., Antonenkova, N., Antoniou, A., Goldgar, D., Beattie, M., Beckmann, M., Birrer, M., Bogdanova, N., Bolton, K., Brewster, W., Brooks-Wilson, A., Brown, R., Butzow, R., Caldes, T., Caligo, M., Campbell, I., Chang-Claude, J., Chen, Y., Cook, L., Couch, F., Cramer, D., Cunningham, J., Despierre, E., Doherty, J., D√∂rk, T., D√ľrst, M., Eccles, D., Ekici, A., Easton, D., Fasching, P., de Fazio, A., Fenstermacher, D., Flanagan, J., Fridley, B., Friedman, E., Gao, B., Sinilnikova, O., Gentry-Maharaj, A., Godwin, A., Goode, E., Goodman, M., Gross, J., Hansen, T., Harnett, P., Rookus, M., Heikkinen, T., Hein, R., H√łgdall, C., H√łgdall, E., Iversen, E., Jakubowska, A., Johnatty, S., Karlan, B., Kauff, N., Kaye, S., Chenevix-Trench, G., Kelemen, L., Kiemeney, L., Kjaer, S., Lambrechts, D., Lapolla, J., L√°zaro, C., Le, N., Leminen, A., Leunen, K., Levine, D., Lu, Y., Lundvall, L., Macgregor, S., Marees, T., Massuger, L., McLaughlin, J., Menon, U., Montagna, M., Moysich, K., Narod, S., Nathanson, K., Nedergaard, L., Ness, R., Nevanlinna, H., Nickels, S., Osorio, A., Paul, J., Pearce, C., Phelan, C., Pike, M., Radice, P., Rossing, M., Schildkraut, J., Sellers, T., Singer, C., Song, H., Stram, D., Sutphen, R., Lindblom, A., Terry, K., Tsai, Y., van Altena, A., Vergote, I., Vierkant, R., Vitonis, A., Walsh, C., Wang-Gohrke, S., Wappenschmidt, B., Wu, A., Ziogas, A., Berchuck, A., Risch, H. (2011), The Role of KRAS rs61764370 in Invasive Epithelial Ovarian Cancer: Implications for Clinical Testing. Clinical Cancer Research. 17(11), 3742-3750. [Abstract]
  • Anglesio, M., George, J., Kulbe, H., Friedlander, M., Rischin, D., Lemech, C., Power, J., Coward, J., Cowin, P., House, C., Chakravarty, P., Gorringe, K., Campbell, I., Okamoto, A., Birrer, M., Huntsman, D., de Fazio, A., Kalloger, S., Balkwill, F., Gilks, C., Bowtell, D. (2011), IL6-STAT3-HIF Signaling and Therapeutic Response to the Angiogenesis Inhibitor Sunitinib in Ovarian Clear Cell Cancer. Clinical Cancer Research. 17(8), 2538-2548. [Abstract]
  • Emmanuel, C., Gava, N., Kennedy, C., Balleine, R., Sharma, R., Wain, G., Brand, A., Hogg, R., Etemadmoghadam, D., George, J., Birrer, M., Clarke, C., Chenevix-Trench, G., Bowtell, D., Harnett, P., Defazio, A. (2011), Comparison of expression profiles in ovarian epithelium in vivo and ovarian cancer identifies novel candidate genes involved in disease pathogenesis. PLoS One. 6(3), e17617. [Abstract]
  • Helland, √., Anglesio, M., George, J., Cowin, P., Johnstone, C., House, C., Sheppard, K., Etemadmoghadam, D., Melnyk, N., Rustgi, A., Phillips, W., Johnsen, H., Holm, R., Kristensen, G., Birrer, M., Pearson, R., B√łrresen-Dale, A., Huntsman, D., deFazio, A., Creighton, C., Smyth, G., Bowtell, D. (2011), Deregulation of MYCN, LIN28B and LET7 in a molecular subtype of aggressive high-grade serous ovarian cancers. PLoS One. 6(4), e18064. [Abstract]

2010

   
  • Price, M., Butow, P., Costa, D., King, M., Aldridge, L., Fardell, J., Defazio, A., Webb, P. (2010), Prevalence and predictors of anxiety and depression in women with invasive ovarian cancer and their caregivers. The Medical Journal of Australia. 193(5), S52-S57. [Abstract]
  • Johnatty, S., Beesley, J., Chen, X., Macgregor, S., Duffy, D., Spurdle, A., deFazio, A., Gava, N., Webb, P., Rossing, M., Doherty, J., Goodman, M., Lurie, G., Thompson, P., Wilkens, L., Ness, R., Moysich, K., Chang-Claude, J., Wang-Gohrke, S., Cramer, D., Terry, K., Hankinson, S., Tworoger, S., Garcia-Closas, M., Yang, H., Lissowska, J., Chanock, S., Pharoah, P., Song, H., Whitemore, A., Pearce, C., Stram, D., Wu, A., Pike, M., Gayther, S., Ramus, S., Menon, U., Gentry-Maharaj, A., Anton-Culver, H., Ziogas, A., Hogdall, E., Kjaer, S., Hogdall, C., Berchuck, A., Schildkraut, J., Iversen, E., Moorman, P., Phelan, C., Sellers, T., Cunningham, J., Vierkant, R., Rider, D., Goode, E., Haviv, I., Chenevix-Trench, G. (2010), Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility "hot-spot". PLoS genetics. 6(7), e1001016. [Abstract]
  • Gordon, L., Scuffham, P., Beesley, V., Green, A., DeFazio, A., Wyld, D., Clavarino, A., Webb, P. (2010), Medical costs and outcomes for Australian women with ovarian cancer: a patient-level analysis over 2.5 years. International Journal of Gynecological Cancer. 20(5), 757-765. [Abstract]
  • Johal, H., Faedo, M., Faltas, J., Lau, A., Mousina, R., Cozzi, P., Defazio, A., Rawlinson, W. (2010), DNA of mouse mammary tumor virus-like virus is present in human tumors influenced by hormones. Journal of Medical Virology. 82(6), 1044-1050. [Abstract]
  • Ahmed, A., Etemadmoghadam, D., Temple, J., Lynch, A., Riad, M., Sharma, R., Stewart, C., Fereday, S., Caldas, C., Defazio, A., Bowtell, D., Brenton, J. (2010), Driver mutations in TP53 are ubiquitous in high grade serous carcinoma of the ovary. The Journal of Pathology. 221(1), 49-56. [Abstract]
  • Hudson, T., Anderson, W., Aretz, A., Barker, A., Bell, C., Bernabe, R., Bhan, M., Calvo, F., Eerola, I., Gerhard, D., Guttmacher, A., Guyer, M., Hemsley, F., Jennings, J., Kerr, D., Klatt, P., Kolar, P., Kusuda, J., Lane, D., Laplace, F., Lu, Y., Nettekoven, G., Ozenberger, B., Peterson, J., Rao, T., Remacle, J., Schafer, A., Shibata, T., Stratton, M., Vockley, J., Watanabe, K., Yang, H., Yuen, M., Knoppers, M., Bobrow, M., Cambon-Thomsen, A., Dressler, L., Dyke, S., Joly, Y., Kato, K., Kennedy, K., Nicolas, P., Parker, M., Rial-Sebbag, E., Romeo-Casabona, C., Shaw, K., Wallace, S., Wiesner, G., Zeps, N., Lichter, P., Biankin, A., Chabannon, C., Chin, L., Clement, B., de Alava, E., Degos, F., Ferguson, M., Geary, P., Hayes, D., Johns, A., Nakagawa, H., Penny, R., Piris, M., Sarin, R., Scarpa, A., van de Vijver, M., Futreal, P., Aburatani, H., Bayes, M., Bowtell, D., Campbell, P., Estivill, X., Grimmond, S., Gut, I., Hirst, M., Lopez-Otin, C., Majumder, P., Marra, M., Ning, Z., Puente, X., Ruan, Y., Stunnenberg, H., Swerdlow, H., Velculescu, V., Wilson, R., Xue, H., Yang, L., Spellman, P., Bader, G., Boutros, P., Flicek, P., Getz, G., Guigo, R., Guo, G., Haussler, D., Heath, S., Hubbard, T., Jiang, T., Jones, S., Li, Q., Lopez-Bigas, N., Luo, R., Pearson, J., Quesada, V., Raphael, B., Sander, C., Speed, T., Stuart, J., Teague, J., Totoki, Y., Tsunoda, T., Valencia, A., Wheeler, D., Wu, H., Zhao, S., Zhou, G., Stein, L., Lathrop, M., Ouellette, B., Thomas, G., Yoshida, T., Axton, M., Gunter, C., McPherson, J., Miller, L., Kasprzyk, A., Zhang, J., Haider, S., Wang, J., Yung, C., Cross, A., Liang, Y., Gnaneshan, S., Guberman, J., Hsu, J., Chalmers, D., Hasel, K., Kaan, T., Knoppers, B., Lowrance, W., Masui, T., Rodriguez, L., Vergely, C., Cloonan, N., Defazio, A., Eshleman, J., Etemadmoghadam, D., Gardiner, B., Kench, J., Sutherland, R., Tempero, M., Waddell, N., Wilson, P., Gallinger, S., Tsao, M., Shaw, P., Petersen, G., Mukhopadhyay, D., DePinho, R., Thayer, S., Muthuswamy, L., Shazand, K., Beck, T., Sam, M., Timms, L., Ballin, V., Ji, J., Zhang, X., Chen, F., Hu, X., Yang, Q., Tian, G., Zhang, L., Xing, X., Li, X., Zhu, Z., Yu, Y., Yu, J., Tost, J., Brennan, P., Holcatova, I., Zaridze, D., Brazma, A., Egevad, L., Prokhortchouk, E., Banks, R., Uhlen, M., Viksna, J., Ponten, F., Skryabin, K., Birney, E., Borg, A., Borresen-Dale, A., Caldas, C., Foekens, J., Martin, S., Reis-Filho, J., Richardson, A., Sotiriou, C., van't Veer, L., Birnbaum, D., Blanche, H., Boucher, P., Boyault, S., Masson-Jacquemier, J., Pauporte, I., Pivot, X., Vincent-Salomon, A., Tabone, E., Theillet, C., Treilleux, I., Bioulac-Sage, P., Decaens, T., Franco, D., Gut, M., Samuel, D., Zucman-Rossi, J., Eils, R., Brors, B., Korbel, J., Korshunov, A., Landgraf, P., Lehrach, H., Pfister, S., Radlwimmer, B., Reifenberger, G., Taylor, M., von Kalle, C., Majumder, P., Pederzoli, P., Lawlor, R., Delledonne, M., Bardelli, A., Gress, T., Klimstra, D., Zamboni, G., Nakamura, Y., Miyano, S., Fujimoto, A., Campo, E., de Sanjose, S., Montserrat, E., Gonzalez-Diaz, M., Jares, P., Himmelbaue, H., Bea, S., Aparicio, S., Easton, D., Collins, F., Compton, C., Lander, E., Burke, W., Green, A., Hamilton, S., Kallioniemi, O., Ley, T., Liu, E., Wainwright, B., Int Canc Genome, C. (2010), International network of cancer genome projects. Nature. 464, 993-998. [Abstract]
  • Byrne, J., Maleki, S., Hardy, J., Gloss, B., Murali, R., Scurry, J., Fanayan, S., Emmanuel, C., Hacker, N., Sutherland, R., Defazio, A., O'Brien, P. (2010), MAL2 and tumor protein D52 (TPD52) are frequently overexpressed in ovarian carcinoma, but differentially associated with histological subtype and patient outcome. BMC Cancer. 10, 497. [Abstract]

2009

   
  • Price, M., Zachariae, R., Butow, P., Defazio, A., Chauhan, D., Espie, C., Friedlander, M., Webb, P. (2009), Prevalence and predictors of insomnia in women with invasive ovarian cancer: Anxiety a major factor. European journal of cancer (Oxford, England : 1990). 45(18), 3262-70. [Abstract]
  • Shah, S., K√∂bel, M., Senz, J., Morin, R., Clarke, B., Wiegand, K., Leung, G., Zayed, A., Mehl, E., Kalloger, S., Sun, M., Giuliany, R., Yorida, E., Jones, S., Varhol, R., Swenerton, K., Miller, D., Clement, P., Crane, C., Madore, J., Provencher, D., Leung, P., DeFazio, A., Khattra, J., Turashvili, G., Zhao, Y., Zeng, T., Glover, J., Vanderhyden, B., Zhao, C., Parkinson, C., Jimenez-Linan, M., Bowtell, D., Mes-Masson, A., Brenton, J., Aparicio, S., Boyd, N., Hirst, M., Gilks, C., Marra, M., Huntsman, D. (2009), Mutation of FOXL2 in granulosa-cell tumors of the ovary. New England Journal of Medicine. 360(26), 2719-2729. [Abstract]
  • Johnatty, S., Beesley, J., Chen, X., Spurdle, A., Defazio, A., Webb, P., Goode, E., Rider, D., Vierkant, R., Anderson, S., Wu, A., Pike, M., Van Den Berg, D., Moysich, K., Ness, R., Doherty, J., Rossing, M., Pearce, C., Chenevix-Trench, G. (2009), Polymorphisms in the FGF2 gene and risk of serous ovarian cancer: results from the ovarian cancer association consortium. Twin research and human genetics. 12(3), 269-275. [Abstract]
  • Etemadmoghadam, D., deFazio, A., Beroukhim, R., Mermel, C., George, J., Getz, G., Tothill, R., Okamoto, A., Raeder, M., Harnett, P., Lade, S., Akslen, L., Tinker, A., Locandro, B., Alsop, K., Chiew, Y., Traficante, N., Fereday, S., Johnson, D., Fox, S., Sellers, W., Urashima, M., Salvesen, H., Meyerson, M., Bowtell, D. (2009), Integrated genome-wide DNA copy number and expression analysis identifies distinct mechanisms of primary chemoresistance in ovarian carcinomas. Clinical Cancer Research. 15(4), 1417-1427. [Abstract]

2008

   
  • Anglesio, M., Arnold, J., George, J., Tinker, A., Tothill, R., Waddell, N., Simms, L., Locandro, B., Fereday, S., Traficante, N., Russell, P., Sharma, R., Birrer, M., deFazio, A., Chenevix-Trench, G., Bowtell, D. (2008), Mutation of ERBB2 provides a novel alternative mechanism for the ubiquitous activation of RAS-MAPK in ovarian serous low malignant potential tumors. Molecular cancer research. 6(11), 1678-1690. [Abstract]
  • Scurr, L., Guminski, A., Chiew, Y., Balleine, R., Sharma, R., Lei, Y., Pryor, K., Wain, G., Brand, A., Byth, K., Kennedy, C., Rizos, H., Harnett, P., Defazio, A. (2008), Ankyrin Repeat Domain 1, ANKRD1, a Novel Determinant of Cisplatin Sensitivity Expressed in Ovarian Cancer. Clinical Cancer Research. 14(21), 6924-6932. [Abstract]
  • Tothill, R., Tinker, A., George, J., Brown, R., Fox, S., Lade, S., Johnson, D., Trivett, M., Etemadmoghadam, D., Locandro, B., Traficante, N., Fereday, S., Hung, J., Chiew, Y., Haviv, I., Gertig, D., DeFazio, A., Bowtell, D. (2008), Novel molecular subtypes of serous and endometrioid ovarian cancer linked to clinical outcome. Clinical cancer research. 14(16), 5198-5208. [Abstract]
  • O'Brien, P., Davies, M., Scurry, J., Smith, A., Barton, C., Henderson, M., Saunders, D., Gloss, B., Patterson, K., Clancy, J., Heinzelmann-Schwarz, V., Murali, R., Scolyer, R., Zeng, Y., Williams, E., Scurr, L., Defazio, A., Quinn, D., Watts, C., Hacker, N., Henshall, S., Sutherland, R. (2008), The E3 ubiquitin ligase EDD is an adverse prognostic factor for serous epithelial ovarian cancer and modulates cisplatin resistance in vitro. British Journal of Cancer. 98(11), 1880. [Abstract]
  • Gava, N., L Clarke, C., Bye, C., Byth, K., deFazio, A. (2008), Global gene expression profiles of ovarian surface epithelial cells in vivo. Journal of Molecular Endocrinology. 40(6), 281-296. [Abstract]
  • Johnatty, S., Beesley, J., Paul, J., Fereday, S., Spurdle, A., Webb, P., Byth, K., Marsh, S., McLeod, H., Harnett, P., Brown, R., de Fazio, A., Chenevix-Trench, G. (2008), ABCB1 (MDR 1) polymorphisms and progression-free survival among women with ovarian cancer following paclitaxel/carboplatin chemotherapy. Clinical Cancer Research. 14(17), 5594-5601. [Abstract]