Dr Anne Cust

Senior Research Fellow
Public Health, School of Public Health

D02 - QEII Research Institute for Mothers and Infants
The University of Sydney
NSW 2006 Australia

T: +61 2 9114 1944
F: +61 2 9114 1946
W: Related website

Biographical details

Dr Anne Cust is an epidemiologist with the Cancer Epidemiology and Services Research group, Sydney School of Public Health, The University of Sydney. She is currently the recipient of an Early Career Development Fellowship from the Cancer Institute NSW and a public health postdoctoral fellowship from the National Health and Medical Research Council (NHMRC). Her qualifications include a PhD from The University of Sydney and the Université Claude Bernard Lyon 1, Lyon, France, MPH(Hons) from The University of Sydney, BSc from The University of Queensland and BA from The University of Queensland. She worked in perinatal research and neonatal clinical trials at The University of Sydney for 5 years before completing a PhD in cancer epidemiology in 2007. Her PhD thesis examined the ‘Lifestyle and metabolic determinants of endometrial cancer’. She was enrolled under a cotutelle agreement between the School of Public Health, University of Sydney, and the Université Claude Bernard Lyon 1, Lyon, France. In Lyon, she was based at the WHO International Agency for Research on Cancer, where she had the opportunity to work with investigators on the large ‘European Prospective Investigation into Cancer and Nutrition (EPIC)’ cohort study. Subsequently, she worked as a postdoctoral fellow at the Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, School of Population Health, University of Melbourne, gaining additional training in genetic epidemiology. She returned to Sydney in January 2011. In 2007, she received the prestigious Cancer Institute NSW Premier's Award for Outstanding Research Scholar. She is a Chief Investigator on a NHMRC-funded project investigating the genetic and environmental causes of melanoma, especially in young people diagnosed under 40 years of age, and has also been a chief investigator on grants from the Victorian Cancer Agency and the Fondation de France. Dr Cust has published more than forty peer-reviewed papers. Dr Cust is a reviewer for more than twenty international journals. She is the primary supervisor of 3 PhD students and 1 MPhil student. She is a member of the Australasian Epidemiological Association (AEA), American Association for Cancer Research (AACR), Melanoma Genetics International Research Consortium (GenoMEL), GEM (Genes, Environment and Melanoma) Study, and Society for Melanoma Research. CESR website: http://sydney.edu.au/medicine/research/cancer-epidemiology-services/index.php

Research interests

My main research aims are to identify causes of cancer, improve cancer control, early diagnosis, and improve the health outcomes of people with cancer. I study both genetic causes of cancer as well as nongenetic causes such as lifestyle, behaviours and the environment, for example, sun exposure, use of solariums, physical activity, overweight, and diet. Most of my research is collaborative, working with other researchers, clinicians, laboratory researchers and policy makers. I am interested in all cancer types although my main current research is on melanoma and gynaecological cancers.

Teaching areas

For over nine years, I have been involved in teaching and tutoring postgraduate epidemiology. I was the course coordinator of Epidemiology and Biostatistics II at The University of Melbourne in 2009, and am currently the course coordinator for Genetics and Public Health PUBH5116 at The University of Sydney.

PhD and Masters' project opportunities

Australian Melanoma Family Study   +

+ indicates the opportunity is full and unavailable.


Gynaecological cancer; Melanoma and skin cancer; Public health; Epidemiology; Genetics

International links

United States. (several international) I am a member of the GEM (Genes, Environment and Melanoma) international consortium, a population-based study of risk factors for melanoma development and progression.
Canada. (Alberta Health Services-Cancer Care) I have collaborated on several research projects with Professor Christine Friedenreich, Alberta, Canada, in relation to physical activity, anthropometry and cancer risk.
France. (International Agency for Research on Cancer, Lyon, France) I spent two years as part of my PhD working at the Nutrition and Hormones Unit at the International Agency for Research on Cancer, Lyon, France.
United Kingdom. (University of Leeds, plus other institutions in the US and Europe) I am a member of the International Melanoma Genetics Consortium (GenoMEL).


2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009


  • Watts, C., Cust, A., Menzies, S., Coates, E., Mann, G., Morton, R. (2015), Specialized Surveillance for Individuals at High Risk for Melanoma: A Cost Analysis of a High-Risk Clinic. JAMA Dermatology. 151(2), 178-186. [Abstract]
  • Watts, C., Dieng, M., Morton, R., Mann, G., Menzies, S., Cust, A. (2015), Clinical practice guidelines for identification, screening and follow-up of individuals at high risk of primary cutaneous melanoma: a systematic review. The British Journal of Dermatology. 172(1), 33-47. [Abstract]


  • Vuong, K., McGeechan, K., Armstrong, B., Cust, A. (2014), Occupational sun exposure and risk of melanoma according to anatomical site. International Journal of Cancer. 134(11), 2735-2741. [Abstract]
  • Iles, M., Bishop, D., Taylor, J., Hayward, N., Brossard, M., Cust, A., Dunning, A., Lee, J., Moses, E., Akslen, L., Andresen, P., Avril, M., Azizi, E., Scarrà, G., Brown, K., DÄ¿bniak, T., Elder, D., Friedman, E., Ghiorzo, P., Gillanders, E., Goldstein, A., Gruis, N., Hansson, J., Harland, M., Helsing, P., Hočevar, M., Höiom, V., Ingvar, C., Kanetsky, P., Landi, M., Lang, J., Lathrop, G., LubiÅ¿ski, J., Mackie, R., Martin, N., Molven, A., Montgomery, G., NovakoviÄ¿, S., Olsson, H., Puig, S., Puig-Butille, J., Radford-Smith, G., Randerson-Moor, J., van der Stoep, N., van Doorn, R., Whiteman, D., MacGregor, S., Pooley, K., Ward, S., Mann, G., Amos, C., Pharoah, P., Demenais, F., Law, M., Newton Bishop, J., Barrett, J. (2014), The effect on melanoma risk of genes previously associated with telomere length. Journal of the National Cancer Institute. 106(10), pii: dju267. [Abstract]
  • Berwick, M., Reiner, A., Paine, S., Armstrong, B., Kricker, A., Goumas, C., Cust, A., Thomas, N., Groben, P., From, L., Busam, K., Orlow, I., Marrett, L., Gallagher, R., Gruber, S., Anton-Culver, H., Rosso, S., Zanetti, R., Kanetsky, P., Dwyer, T., Venn, A., Lee-Taylor, J., Begg, C. (2014), Sun Exposure and Melanoma Survival: A GEM Study. Cancer Epidemiology, Biomarkers & Prevention. 23(10), 2145-2152. [Abstract]
  • Song, F., Amos, C., Lee, J., Lian, C., Fang, S., Liu, H., MacGregor, S., Iles, M., Lindeman, N., Montgomery, G., Duffy, D., Cust, A., Jenkins, M., Whiteman, D., Kefford, R., Giles, G., Armstrong, B., Aitken, J., Hopper, J., Brown, K., Martin, N., Mann, G., Bishop, D., Newton Bishop, J., Kraft, P., Qureshi, A., Kanetsky, P., Hayward, N., Hunter, D., Wei, Q., Han, J. (2014), Identification of a melanoma susceptibility locus and somatic mutation in TET2. Carcinogenesis. 35(9), 2097-2101. [Abstract]
  • Berwick, M., MacArthur, J., Orlow, I., Kanetsky, P., Begg, C., Luo, L., Reiner, A., Sharma, A., Armstrong, B., Kricker, A., Cust, A., Marrett, L., Gruber, S., Anton-Culver, H., Zanetti, R., Rosso, S., Gallagher, R., Dwyer, T., Venn, A., Busam, K., From, L., White, K., Thomas, N. (2014), MITF E318K's effect on melanoma risk independent of, but modified by, other risk factors. Pigment Cell & Melanoma Research. 27(3), 485-488. [Abstract]
  • Vuong, K., McGeechan, K., Armstrong, B., Cust, A. (2014), Risk prediction models for incident primary cutaneous melanoma: a systematic review. JAMA Dermatology. 150(4), 434-444. [Abstract]
  • Dieng, M., Watts, C., Kasparian, N., Morton, R., Mann, G., Cust, A. (2014), Improving subjective perception of personal cancer risk: systematic review and meta-analysis of educational interventions for people with cancer or at high risk of cancer. Psycho-Oncology. 23(6), 613-625. [Abstract]


  • Cust, A., Goumas, C., Vuong, K., Davies, J., Barrett, J., Holland, E., Schmid, H., Agha-Hamilton, C., Armstrong, B., Kefford, R., Aitken, J., Giles, G., Bishop, D., Newton-Bishop, J., Hopper, J., Mann, G., Jenkins, M. (2013), MC1R genotype as a predictor of early-onset melanoma, compared with self-reported and physician-measured traditional risk factors: an Australian case-control-family study. BMC Cancer. 13(1), 406. [Abstract]
  • Qian, J., Liu, H., Wei, S., Liu, Z., Li, Y., Wang, L., Chen, W., Amos, C., Lee, J., Iles, M., Law, M., Cust, A., Barrett, J., Montgomery, G., Taylor, J., Bishop, J., Macgregor, S., Bishop, D., Mann, G., Hayward, N., Wei, Q. (2013), Association between putative functional variants in the PSMB9 gene and risk of melanoma--re-analysis of published melanoma genome-wide association studies. Pigment Cell & Melanoma Research. 26(3), 392-401. [Abstract]
  • Liu, H., Wang, L., Liu, Z., Chen, W., Amos, C., Lee, J., Iles, M., Law, M., Barrett, J., Montgomery, G., Taylor, J., MacGregor, S., Cust, A., Newton Bishop, J., Hayward, N., Bishop, D., Mann, G., Affleck, P., Wei, Q. (2013), Association between functional polymorphisms in genes involved in the MAPK signaling pathways and cutaneous melanoma risk. Carcinogenesis. 34(4), 885-892. [Abstract]
  • Iles, M., Law, M., Stacey, S., Han, J., Fang, S., Pfeiffer, R., Harland, M., Macgregor, S., Taylor, J., Aben, K., Akslen, L., Avril, M., Azizi, E., Bakker, B., Benediktsdottir, K., Bergman, W., Scarrà, G., Brown, K., Calista, D., Chaudru, V., Fargnoli, M., Cust, A., Demenais, F., de Waal, A., DÄ¿bniak, T., Elder, D., Friedman, E., Galan, P., Ghiorzo, P., Gillanders, E., Goldstein, A., Gruis, N., Hansson, J., Helsing, P., Hočevar, M., Höiom, V., Hopper, J., Ingvar, C., Janssen, M., Jenkins, M., Kanetsky, P., Kiemeney, L., Lang, J., Lathrop, G., Leachman, S., Lee, J., LubiÅ¿ski, J., Mackie, R., Mann, G., Martin, N., Mayordomo, J., Molven, A., Mulder, S., Nagore, E., NovakoviÄ¿, S., Okamoto, I., Olafsson, J., Olsson, H., Pehamberger, H., Peris, K., Grasa, M., Planelles, D., Puig, S., Puig-Butille, J., Randerson-Moor, J., Requena, C., Rivoltini, L., Rodolfo, M., Santinami, M., Sigurgeirsson, B., Snowden, H., Song, F., Sulem, P., Thorisdottir, K., Tuominen, R., Van Belle, P., van der Stoep, N., van Rossum, M., Wei, Q., Wendt, J., Zelenika, D., Zhang, M., Landi, M., Thorleifsson, G., Bishop, D., Amos, C., Hayward, N., Stefansson, K., Bishop, J., Barrett, J. (2013), A variant in FTO shows association with melanoma risk not due to BMI. Nature Genetics. 45(4), 428-432, 432e1. [Abstract]


  • Cust, A., Goumas, C., Holland, E., Agha-Hamilton, C., Aitken, J., Armstrong, B., Giles, G., Kefford, R., Schmid, H., Hopper, J., Mann, G., Jenkins, M. (2012), MC1R genotypes and risk of melanoma before age 40 years: A population-based case-control-family study. International Journal of Cancer. 131(3), E269-281. [Abstract]


  • Amos, C., Wang, L., Lee, J., Gershenwald, J., Chen, W., Fang, S., Kosoy, R., Zhang, M., Qureshi, A., Vattathil, S., Schacherer, C., Gardner, J., Wang, Y., Tim Bishop, D., Barrett, J., Macgregor, S., Hayward, N., Martin, N., Duffy, D., Mann, G., Cust, A., Hopper, J., Brown, K., Grimm, E., Xu, Y., Han, Y., Jing, K., McHugh, C., Laurie, C., Doheny, K., Pugh, E., Seldin, M., Han, J., Wei, Q. (2011), Genome-wide association study identifies novel loci predisposing to cutaneous melanoma. Human Molecular Genetics. 20(24), 5012-5023. [Abstract]
  • Yokoyama, S., Woods, S., Boyle, G., Aoude, L., MacGregor, S., Zismann, V., Gartside, M., Cust, A., Haq, R., Harland, M., Taylor, J., Duffy, D., Holohan, K., Dutton-Regester, K., Palmer, J., Bonazzi, V., Stark, M., Symmons, J., Law, M., Schmidt, C., Lanagan, C., O'Connor, L., Holland, E., Schmid, H., Maskiell, J., Jetann, J., Ferguson, M., Jenkins, M., Kefford, R., Giles, G., Armstrong, B., Aitken, J., Hopper, J., Whiteman, D., Pharoah, P., Easton, D., Dunning, A., Newton-Bishop, J., Montgomery, G., Martin, N., Mann, G., Bishop, D., Tsao, H., Trent, J., Fisher, D., Hayward, N., Brown, K. (2011), A novel recurrent mutation in MITF predisposes to familial and sporadic melanoma. Nature. 480(7375), 99-103. [Abstract]
  • Barrett, J., Iles, M., Harland, M., Taylor, J., Aitken, J., Andresen, P., Akslen, L., Armstrong, B., Avril, M., Azizi, E., Bakker, B., Bergman, W., Bianchi-Scarrà, G., Bressac-de Paillerets, B., Calista, D., Cannon-Albright, L., Corda, E., Cust, A., Dębniak, T., Duffy, D., Dunning, A., Easton, D., Friedman, E., Galan, P., Ghiorzo, P., Giles, G., Hansson, J., Hocevar, M., Höiom, V., Hopper, J., Ingvar, C., Janssen, B., Jenkins, M., Jönsson, G., Kefford, R., Landi, G., Landi, M., Lang, J., Lubiński, J., Mackie, R., Malvehy, J., Martin, N., Molven, A., Montgomery, G., van Nieuwpoort, F., Novakovic, S., Olsson, H., Pastorino, L., Puig, S., Puig-Butille, J., Randerson-Moor, J., Snowden, H., Tuominen, R., Van Belle, P., van der Stoep, N., Whiteman, D., Zelenika, D., Han, J., Fang, S., Lee, J., Wei, Q., Lathrop, G., Gillanders, E., Brown, K., Goldstein, A., Kanetsky, P., Mann, G., Macgregor, S., Elder, D., Amos, C., Hayward, N., Gruis, N., Demenais, F., Bishop, J., Bishop, D. (2011), Genome-wide association study identifies three new melanoma susceptibility loci. Nature genetics. 43(11), 1108-13. [Abstract]
  • Macgregor, S., Montgomery, G., Liu, J., Zhao, Z., Henders, A., Stark, M., Schmid, H., Holland, E., Duffy, D., Zhang, M., Painter, J., Nyholt, D., Maskiell, J., Jetann, J., Ferguson, M., Cust, A., Jenkins, M., Whiteman, D., Olsson, H., Puig, S., Bianchi-Scarrà, G., Hansson, J., Demenais, F., Landi, M., Dębniak, T., Mackie, R., Azizi, E., Bressac-de Paillerets, B., Goldstein, A., Kanetsky, P., Gruis, N., Elder, D., Newton-Bishop, J., Bishop, D., Iles, M., Helsing, P., Amos, C., Wei, Q., Wang, L., Lee, J., Qureshi, A., Kefford, R., Giles, G., Armstrong, B., Aitken, J., Han, J., Hopper, J., Trent, J., Brown, K., Martin, N., Mann, G., Hayward, N. (2011), Genome-wide association study identifies a new melanoma susceptibility locus at 1q21.3. Nature Genetics. 43(11), 1114-1118. [Abstract]
  • Cust, A., Jenkins, M., Goumas, C., Armstrong, B., Schmid, H., Aitken, J., Giles, G., Kefford, R., Hopper, J., Mann, G. (2011), Early-life sun exposure and risk of melanoma before age 40 years. Cancer causes & control : CCC. 22(6), 885-97. [Abstract]
  • Cust, A., Armstrong, B., Goumas, C., Jenkins, M., Schmid, H., Hopper, J., Kefford, R., Giles, G., Aitken, J., Mann, G. (2011), Sunbed use during adolescence and early adulthood is associated with increased risk of early-onset melanoma. International journal of cancer. Journal international du cancer. 128(10), 2425-35. [Abstract]
  • Cust, A., Harland, M., Makalic, E., Schmidt, D., Dowty, J., Aitken, J., Agha-Hamilton, C., Armstrong, B., Barrett, J., Chan, M., Chang, Y., Gascoyne, J., Giles, G., Holland, E., Kefford, R., Kukalizch, K., Lowery, J., Randerson-Moor, J., Schmid, H., Taylor, C., Whitaker, L., Hopper, J., Newton-Bishop, J., Mann, G., Bishop, D., Jenkins, M. (2011), Melanoma risk for CDKN2A mutation carriers who are relatives of population-based case carriers in Australia and the UK. Journal of medical genetics. 48(4), 266-72. [Abstract]
  • Cust, A. (2011), Physical Activity and Gynecologic Cancer Prevention. In: Physical Activity and Cancer. (pp.159-188).Germany: Springer.


  • Lahmann, P., Cust, A., Friedenreich, C., Schulz, M., Lukanova, A., Kaaks, R., Lundin, E., Tjønneland, A., Halkjaer, J., Severinsen, M., Overvad, K., Fournier, A., Chabbert-Buffet, N., Clavel-Chapelon, F., Dossus, L., Pischon, T., Boeing, H., Trichopoulou, A., Lagiou, P., Naska, A., Palli, D., Grioni, S., Mattiello, A., Tumino, R., Sacerdote, C., Redondo, M., Jakszyn, P., Sánchez, M., Tormo, M., Ardanaz, E., Arriola, L., Manjer, J., Jirström, K., Bueno-de-Mesquita, H., May, A., Peeters, P., Onland-Moret, N., Bingham, S., Khaw, K., Allen, N., Spencer, E., Rinaldi, S., Slimani, N., Chajes, V., Michaud, D., Norat, T., Riboli, E. (2010), Anthropometric measures and epithelial ovarian cancer risk in the European Prospective Investigation into Cancer and Nutrition. International Journal of Cancer. 126(10), 2404-2415. [Abstract]


  • Cust, A., Schmid, H., Maskiell, J., Jetann, J., Ferguson, M., Holland, E., Agha-Hamilton, C., Jenkins, M., Kelly, J., Kefford, R., Giles, G., Armstrong, B., Aitken, J., Hopper, J., Mann, G. (2009), Population-based, case-control-family design to investigate genetic and environmental influences on melanoma risk: Australian Melanoma Family Study. American Journal of Epidemiology. 170(12), 1541-1554. [Abstract]
  • van Bakel, M., Kaaks, R., Feskens, E., Rohrmann, S., Welch, A., Pala, V., Avloniti, K., van der Schouw, Y., van der A, D., Du, H., Halkjaer, J., Tormo, M., Cust, A., Brighenti, F., Beulens, J., Ferrari, P., Biessy, C., Lentjes, M., Spencer, E., Panico, S., Masala, G., Bueno-de-Mesquita, H., Peeters, P., Trichopoulou, A., Psaltopoulou, T., Clavel-Chapelon, F., Touvier, M., Skeie, G., Rinaldi, S., Sonestedt, E., Johansson, I., Schulze, M., Ardanaz, E., Buckland, G., Tjønneland, A., Overvad, K., Bingham, S., Riboli, E., Slimani, N. (2009), Dietary glycaemic index and glycaemic load in the European Prospective Investigation into Cancer and Nutrition. European Journal of Clinical Nutrition. 63 Suppl 4, S188-205. [Abstract]
  • Cust, A., Skilton, M., van Bakel, M., Halkjaer, J., Olsen, A., Agnoli, C., Psaltopoulou, T., Buurma, E., Sonestedt, E., Chirlaque, M., Rinaldi, S., Tjønneland, A., Jensen, M., Clavel-Chapelon, F., Boutron-Ruault, M., Kaaks, R., Nöthlings, U., Chloptsios, Y., Zylis, D., Mattiello, A., Caini, S., Ocké, M., van der Schouw, Y., Skeie, G., Parr, C., Molina-Montes, E., Manjer, J., Johansson, I., McTaggart, A., Key, T., Bingham, S., Riboli, E., Slimani, N. (2009), Total dietary carbohydrate, sugar, starch and fibre intakes in the European Prospective Investigation into Cancer and Nutrition. European Journal of Clinical Nutrition. 63 Suppl 4, S37-60. [Abstract]
  • Cust, A., Armstrong, B., Smith, B., Chau, J., van der Ploeg, H., Bauman, A. (2009), Self-Reported Confidence in Recall as a Predictor of Validity and Repeatability of Physical Activity Questionnaire Data. Epidemiology (Cambridge, Mass.). 20(0), 433-41. [Abstract]
  • Cust, A., Stocks, T., Lukanova, A., Lundin, E., Hallmans, G., Kaaks, R., Jonsson, H., Stattin, P. (2009), The influence of overweight and insulin resistance on breast cancer risk and tumour stage at diagnosis: a prospective study. Breast Cancer Research and Treatment. 113(3), 567-576. [Abstract]
  • Lahmann, P., Friedenreich, C., Schulz, M., Cust, A., Lukanova, A., Kaaks, R., Tjønneland, A., Johnsen, N., Overvad, K., Fournier, A., Boutron-Ruault, M., Clavel Chapelon, F., Boeing, H., Linseisen, J., Rohrmann, S., Trichopoulou, A., Lagiou, P., Trichopoulos, D., Palli, D., Mattiello, A., Sacerdote, C., Agnoli, C., Tumino, R., Quirós, J., Larrañaga, N., Agudo, A., Sánchez, M., Berglund, G., Manjer, J., Monninkhof, E., Peeters, P., Bueno-de-Mesquita, H., May, A., Allen, N., Khaw, K., Bingham, S., Rinaldi, S., Ferrari, P., Riboli, E. (2009), Physical activity and ovarian cancer risk: the European Prospective Investigation into Cancer and Nutrition. Cancer Epidemiology, Biomarkers & Prevention. 18(1), 351-354. [Abstract]