Dr Jonathon Arnold

Senior Lecturer
Pharmacology, School of Medical Sciences
Bosch Institute

D06 - Blackburn Building
The University of Sydney
NSW 2006 Australia

T: +61 2 9036 5361
F: +61 2 9351 7328
E:

Research interests

Dr Jonathon is an internationally-recognised researcher in the pharmacology of cannabis and the cannabinoids (cannabis-like drugs).

Keywords

Neuropharmacology; Schizophrenia; Pharmacology; Substance abuse and addiction; Behavioural neuroscience

International links

Iran. (Babol Medical Science University) Collaboration with Dr Ibrahim Zabihi.
France. (University of Bordeaux) Collaboration with Prof Jacques Micheau on the effects on cannabinoids on cognition..

Publications

2011 | 2010 | 2009 | 2008 | 2007 | 2006

2011

   
  • Klein, C., Karanges, E., Spiro, A., Wong, A., Spencer, J., Huynh, T., Gunasekaran, N., Karl, T., Long, L., Huang, X., Liu, K., Arnold, J., McGregor, I. (2011), Cannabidiol potentiates Δ9-tetrahydrocannabinol (THC) behavioural effects and alters THC pharmacokinetics during acute and chronic treatment in adolescent rats. Psychopharmacology. 218(2), 443-57. [Abstract]
  • Boucher, A., Arnold, J., Hunt, G., Spiro, A., Spencer, J., Brown, C., McGregor, I., Bennett, M., Kassiou, M. (2011), Resilience and reduced c-Fos expression in P2X7 receptor knockout mice exposed to repeated forced swim test. Neuroscience. 189(2011), 170-7. [Abstract]
  • Sokolic, L., Long, L., Hunt, G., Arnold, J., McGregor, I. (2011), Disruptive effects of the prototypical cannabinoid Δ9-tetrahydrocannabinol and the fatty acid amide inhibitor URB-597 on go/no-go auditory discrimination performance and olfactory reversal learning in rats. Behavioural Pharmacology. 22(3), 191-202. [Abstract]
  • Boucher, A., Hunt, G., Micheau, J., Huang, X., McGregor, I., Karl, T., Arnold, J. (2011), The schizophrenia susceptibility gene neuregulin 1 modulates tolerance to the effects of cannabinoids. The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP). 14, 631-43. [Abstract]
  • Bowen, M., Carson, D., Spiro, A., Arnold, J., McGregor, I. (2011), Adolescent oxytocin exposure causes persistent reductions in anxiety and alcohol consumption and enhances sociability in rats. PloS One. 6(11), e27237. [Abstract]

2010

   
  • van Nieuwenhuijzen, P., Long, L., Hunt, G., Arnold, J., McGregor, I. (2010), Residual social, memory and oxytocin-related changes in rats following repeated exposure to gamma-hydroxybutyrate (GHB), 3,4-methylenedioxymethamphetamine (MDMA) or their combination. Psychopharmacology. 212, 663-74. [Abstract]
  • Arnold, J., Dielenberg, R., McGregor, I. (2010), Cannabinoids increase conditioned ultrasonic vocalisations and cat odour avoidance in rats: Strain differences in drug-induced anxiety. Life sciences. 87(17-18), 572-8. [Abstract]
  • Carson, D., Hunt, G., Guastella, A., Barber, L., Cornish, J., Arnold, J., Boucher, A., McGregor, I. (2010), Systemically administered oxytocin decreases methamphetamine activation of the subthalamic nucleus and accumbens core and stimulates oxytocinergic neurons in the hypothalamus. Addiction biology. 15(4), 448-63. [Abstract]
  • Long, L., Chesworth, R., Arnold, J., Karl, T. (2010), A follow-up study: acute behavioural effects of Delta(9)-THC in female heterozygous neuregulin 1 transmembrane domain mutant mice. Psychopharmacology. 211(3), 277-289. [Abstract]

2009

   
  • Gunasekaran, N., Long, L., Dawson, B., Hansen, G., Richardson, D., Li, K., Arnold, J., McGregor, I. (2009), Reintoxication: the release of fat-stored Delta(9)-tetrahydrocannabinol (THC) into blood is enhanced by food deprivation or ACTH exposure. British Journal of Pharmacology. 158(5), 1330-1337. [Abstract]
  • Boucher, A., Vivier, L., Metna-Laurent, M., Brayda-Bruno, L., Mons, N., Arnold, J., Micheau, J. (2009), Chronic treatment with Delta(9)-tetrahydrocannabinol impairs spatial memory and reduces zif268 expression in the mouse forebrain. Behavioural Pharmacology. 20(1), 45-55. [Abstract]

2008

   
  • Jiwane, A., Holland, A., Soundappan, S., Arnold, J. (2008), An unusual case of bilious vomiting in a neonate. Journal of Paediatrics and Child Health. 44(12), 747-749. [Abstract]
  • Holland, M., Allen, J., Arnold, J. (2008), Interaction of plant cannabinoids with the multidrug transporter ABCC1 (MRP1). European journal of pharmacology. 591, 128-31. [Abstract]
  • Quinn, H., Matsumoto, I., Callaghan, P., Long, L., Arnold, J., Gunasekaran, N., Thompson, M., Dawson, B., Mallet, P., Kashem, M., Matsuda-Matsumoto, H., Iwazaki, T., McGregor, I. (2008), Adolescent Rats Find Repeated Delta(9)-THC Less Aversive Than Adult Rats but Display Greater Residual Cognitive Deficits and Changes in Hippocampal Protein Expression Following Exposure. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 33(0), 1113-26. [Abstract]

2007

   
  • Boucher, A., Hunt, G., Karl, T., Micheau, J., McGregor, I., Arnold, J. (2007), Heterozygous neuregulin 1 mice display greater baseline and Delta(9)-tetrahydrocannabinol-induced c-Fos expression. Neuroscience. 149(4), 861-70. [Abstract]
  • McGregor, I., Arnold, J. (2007), Cannabis reward: biased towards the fairer sex?. British journal of pharmacology. 152(5), 562-4. [Abstract]
  • Holland, M., Lau, D., Allen, J., Arnold, J. (2007), The multidrug transporter ABCG2 (BCRP) is inhibited by plant-derived cannabinoids. British journal of pharmacology. 152(5), 815-24. [Abstract]
  • Boucher, A., Arnold, J., Duffy, L., Schofield, P., Micheau, J., Karl, T. (2007), Heterozygous neuregulin 1 mice are more sensitive to the behavioural effects of Delta9-tetrahydrocannabinol. Psychopharmacology. 192(3), 325-336. [Abstract]

2006

   
  • Karl, T., Duffy, L., Boucher, A., Arnold, J., Schofield, P. (2006), Genetic animal models for neuregulin 1 - valuable tools for schizophrenia research?. Australian and New Zealand Journal of Psychiatry. 40, A115-A115. [Abstract]
  • Holland, M., Panetta, J., Hoskins, J., Bebawy, M., Roufogalis, B., Allen, J., Arnold, J. (2006), The effects of cannabinoids on P-glycoprotein transport and expression in multidrug resistant cells. Biochemical pharmacology. 71(8), 1146-54. [Abstract]