Dr Therese Becker

Research Only Level B Academic
Medicine, Westmead Clinical School
Westmead Millennium Institute for Medical Research

Melanoma and skin cancer; Genetics; Molecular biology; Biological sciences; Cell biology

Publications

Boyd, S., Mijatov, B., Pupo, G., Tran, S., Gowrishankar, K., Shaw, H., Goding, C., Scolyer, R., Mann, G., Kefford, R., Rizos, H., Becker, T. (2013), Oncogenic B-RAF(V600E) Signaling Induces the T-Box3 Transcriptional Repressor to Repress E-Cadherin and Enhance Melanoma Cell Invasion. The Journal of Investigative Dermatology. 133(5), 1269-1277. [Abstract]

Gowrishankar, K., Snoyman, S., Pupo, G., Becker, T., Kefford, R., Rizos, H. (2012), Acquired Resistance to BRAF Inhibition Can Confer Cross-Resistance to Combined BRAF/MEK Inhibition. The Journal of Investigative Dermatology. 132(7), 1850-1859. [Abstract]
Tran, S., Haferkamp, S., Scurr, L., Gowrishankar, K., Becker, T., Desilva, C., Thompson, J., Scolyer, R., Kefford, R., Rizos, H. (2012), Absence of Distinguishing Senescence Traits in Human Melanocytic Nevi. Journal of Investigative Dermatology. 132(9), 2226-2234. [Abstract]

Scurr, L., McKenzie, H., Becker, T., Irvine, M., Lai, K., Mann, G., Scolyer, R., Kefford, R., Rizos, H. (2011), Selective Loss of Wild-Type p16(INK4a) Expression in Human Nevi. The Journal of Investigative Dermatology. 131(11), 2329-2332. [Abstract]

Becker, T., Philipsz, S., Scurr, L., Fung, C., Haferkamp, S., Kefford, R., Rizos, H. (2010), Oncogenic B-RAF(V600E) Promotes Anchorage-Independent Survival of Human Melanocytes. The Journal of investigative dermatology. 130(8), 2144-7. [Abstract]
McKenzie, H., Fung, C., Becker, T., Irvine, M., Mann, G., Kefford, R., Rizos, H. (2010), Predicting functional significance of cancer-associated p16(INK4a) mutations in CDKN2A. Human mutation. 31(6), 692-701. [Abstract]
Scurr, L., Pupo, G., Becker, T., Lai, K., Schrama, D., Haferkamp, S., Irvine, M., Scolyer, R., Mann, G., Becker, J., Kefford, R., Rizos, H. (2010), IGFBP7 is not required for B-RAF-induced melanocyte senescence. Cell. 141(4), 717-727. [Abstract]
Irvine, M., Philipsz, S., Frausto, M., Mijatov, B., Gallagher, S., Fung, C., Becker, T., Kefford, R., Rizos, H. (2010), Amino terminal hydrophobic import signals target the p14(ARF) tumor suppressor to the mitochondria. Cell cycle (Georgetown, Tex.). 9(4), 829-39. [Abstract]
Jiang, C., Lai, F., Tay, K., Croft, A., Rizos, H., Becker, T., Yang, F., Liu, H., Thorne, R., Hersey, P., Zhang, X. (2010), Apoptosis of human melanoma cells induced by inhibition of B-RAF(V600E) involves preferential splicing of bim(S). Cell death & disease. 1(9), e69. [Abstract]

Haferkamp, S., Scurr, L., Becker, T., Frausto, M., Kefford, R., Rizos, H. (2009), Oncogene-Induced Senescence Does Not Require the p16(INK4a) or p14ARF Melanoma Tumor Suppressors. The Journal of investigative dermatology. 129(6), 1983-91. [Abstract]
Haferkamp, S., Tran, S., Becker, T., Scurr, L., Kefford, R., Rizos, H. (2009), The relative contributions of the p53 and pRb pathways in oncogene-induced melanocyte senescence. Aging. 1(6), 542-56. [Abstract]
McKenzie, H., Becker, T., Scurr, L., Kefford, R., Rizos, H. (2009), Wild type and melanoma-associated mutant p16(IN4a) proteins do not oligomerize in vivo. Pigment Cell & Melanoma Research. , 131-133. [Abstract]
Becker, T., Haferkamp, S., Dijkstra, M., Scurr, L., Frausto, M., Diefenbach, E., Scolyer, R., Reisman, D., Mann, G., Kefford, R., Rizos, H. (2009), The chromatin remodelling factor BRG1 is a novel binding partner of the tumor suppressor p16INK4a. Molecular Cancer. 8, 4. [Abstract]

Haferkamp, S., Becker, T., Scurr, L., Kefford, R., Rizos, H. (2008), p16(INK4a)-induced senescence is disabled by melanoma-associated mutations. Aging cell. 7(5), 733-745. [Abstract]