Associate Professor Beric Henderson

Principal Research Fellow
Medicine, Westmead Clinical School
Westmead Millennium Institute for Medical Research

C24 - Westmead Hospital
The University of Sydney
NSW 2006 Australia

T: +61 2 9845 9057
F: +61 2 9845 9012
W: Related website

PhD and Masters' project opportunities

Regulation of beta-catenin subcellular localisation and trafficking in cancer   +

+ indicates the opportunity is full and unavailable.


Molecular biology; Cell biology; Colorectal cancers; Bowel cancer; Breast cancer


2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009


  • Lei, Y., Henderson, B., Emmanuel, C., Harnett, P., Defazio, A. (2015), Inhibition of ANKRD1 sensitizes human ovarian cancer cells to endoplasmic reticulum stress-induced apoptosis. Oncogene. 34(4), 485-495. [Abstract]


  • Mok, M., Cheng, A., Henderson, B. (2014), The ubiquitin ligases RNF8 and RNF168 display rapid but distinct dynamics at DNA repair foci in living cells. The International Journal of Biochemistry & Cell Biology. 57, 27¿34. [Abstract]
  • Martino-Echarri, E., Henderson, B., Brocardo, M. (2014), Targeting the DNA replication checkpoint by pharmacologic inhibition of Chk1 kinase: a strategy to sensitize APC mutant colon cancer cells to 5-fluorouracil chemotherapy. Oncotarget. 5(20), 9889-9900. [Abstract]
  • Jamieson, C., Sharma, M., Henderson, B. (2014), Targeting the β-catenin nuclear transport pathway in cancer. Seminars in Cancer Biology. 27(C), 20-29. [Abstract]
  • Sharma, M., Johnson, M., Brocardo, M., Jamieson, C., Henderson, B. (2014), Wnt Signaling Proteins Associate with the Nuclear Pore Complex: Implications for Cancer. In: Advances in Experimental Medicine and Biology: Cancer Biology and the Nuclear Envelope. (pp.353-372).: Springer.


  • Johnson, M., Sharma, M., Mok, M., Henderson, B. (2013), Stimulation of in vivo nuclear transport dynamics of actin and its co-factors IQGAP1 and Rac1 in response to DNA replication stress. Biochimica et Biophysica Acta. 1833(10), 2334-2347. [Abstract]


  • Mok, M., Henderson, B. (2012), The in vivo dynamic interplay of MDC1 and 53BP1 at DNA damage-induced nuclear foci. The International Journal of Biochemistry & Cell Biology. 44(9), 1398-1409. [Abstract]
  • Johnson, M., Henderson, B. (2012), The scaffolding protein IQGAP1 co-localizes with actin at the cytoplasmic face of the nuclear envelope: implications for cytoskeletal regulation. Bioarchitecture. 2(4), 138-142. [Abstract]
  • Mok, M., Henderson, B. (2012), Three-dimensional imaging reveals the spatial separation of γH2AX-MDC1-53BP1 and RNF8-RNF168-BRCA1-A complexes at ionizing radiation-induced foci. Radiotherapy and Oncology. 103(3), 415-420. [Abstract]
  • Jamieson, C., Sharma, M., Henderson, B. (2012), Wnt signaling from membrane to nucleus: β-catenin caught in a loop. The International Journal of Biochemistry & Cell Biology. 44(6), 847-850. [Abstract]
  • Mok, M., Henderson, B. (2012), The In Vivo Dynamic Organization of BRCA1-A Complex Proteins at DNA Damage-Induced Nuclear Foci. Traffic. 13(6), 800-814. [Abstract]
  • Brodie, K., Henderson, B. (2012), Characterization of BRCA1 protein targeting, dynamics, and function at the centrosome: a role for the nuclear export signal, CRM1, and Aurora A kinase. The Journal of Biological Chemistry. 287(10), 7701-7716. [Abstract]
  • Lui, C., Mills, K., Brocardo, M., Sharma, M., Henderson, B. (2012), APC as a mobile scaffold: Regulation and function at the nucleus, centrosomes, and mitochondria. IUBMB Life. 64(3), 209-214. [Abstract]
  • Brodie, K., Mok, M., Henderson, B. (2012), Characterization of BARD1 targeting and dynamics at the centrosome: the role of CRM1, BRCA1 and the Q564H mutation. Cellular Signalling. 24(2), 451-459. [Abstract]
  • Mok, M., Henderson, B. (2012), A two-step fluorescence-activated cell sorting approach to isolate genetically modified mammalian cells with isopropyl-beta-D-thiogalactoside (IPTG)-inducible gene expression. Cytometry. Part A. 81(2), 101-104. [Abstract]
  • Sharma, M., Jamieson, C., Johnson, M., Molloy, M., Henderson, B. (2012), Specific armadillo repeat sequences facilitate beta-catenin nuclear transport in live cells via direct binding to nucleoporins Nup62, Nup153 and RANBP2/Nup358. The Journal of biological chemistry. 287(2), 819-31. [Abstract]


  • Brocardo, M., Borowiec, J., Henderson, B. (2011), Adenomatous polyposis coli protein regulates the cellular response to DNA replication stress. The international journal of biochemistry & cell biology. 43(9), 1354-64. [Abstract]
  • Jamieson, C., Sharma, M., Henderson, B. (2011), Regulation of β-catenin nuclear dynamics by GSK-3β involves a LEF-1 positive feedback loop. Traffic (Copenhagen, Denmark). 12(8), 983-99. [Abstract]
  • Johnson, M., Sharma, M., Brocardo, M., Henderson, B. (2011), IQGAP1 translocates to the nucleus in early S-phase and contributes to cell cycle progression after DNA replication arrest. The international journal of biochemistry & cell biology. 43(1), 65-73. [Abstract]


  • Flegg, C., Sharma, M., Medina-Palazon, C., Jamieson, C., Galea, M., Brocardo, M., Mills, K., Henderson, B. (2010), Nuclear export and centrosome targeting of the protein phosphatase 2A subunit B56alpha: Role of B56alpha in nuclear export of the catalytic subunit. The Journal of biological chemistry. 285(24), 18144-54. [Abstract]
  • Henderson, B. (2010), Cryptic mitochondrial targeting signals in human ARF: Clues to controlling cancer?. Cell Cycle. 9(5), 866-867. [Abstract]
  • Brodie, K., Henderson, B. (2010), Differential modulation of BRCA1 and BARD1 nuclear localisation and foci assembly by DNA damage. Cellular signalling. 22(2), 291-302. [Abstract]
  • Sharma, M., Henderson, B. (2010), Methods to measure nuclear export of beta-catenin using fixed and live cell assays. In: Methods in Molecular Biology: Transcription Factors Methods and Protocols. (pp.187-197).United States: Humana Press.
  • Mok, M., Henderson, B. (2010), A comparison of BRCA1 nuclear localization with 14 DNA damage response proteins and domains: identification of specific differences between BRCA1 and 53BP1 at DNA damage-induced foci. Cellular Signalling. 22(1), 47-56. [Abstract]


  • Johnson, M., Sharma, M., Henderson, B. (2009), IQGAP1 regulation and roles in cancer. Cellular Signalling. 21(10), 1471-1478. [Abstract]
  • Zheng, G., Lyons, J., Tan, T., Wang, Y., Hsu, T., Min, D., Succar, L., Rangan, G., Hu, M., Henderson, B., Alexander, S., Harris, D. (2009), Disruption of E-Cadherin by Matrix Metalloproteinase Directly Mediates Epithelial-Mesenchymal Transition Downstream of Transforming Growth Factor-{beta}1 in Renal Tubular Epithelial Cells. The American journal of pathology. 175(2), 580-91. [Abstract]
  • Maniccia, A., Lewis, C., Begum, N., Xu, J., Cui, J., Chipitsyna, G., Aysola, K., Reddy, V., Bhat, G., Fujimura, Y., Henderson, B., Reddy, E., Rao, V. (2009), Mitochondrial localization, ELK-1 transcriptional regulation and growth inhibitory functions of BRCA1, BRCA1a, and BRCA1b proteins. Journal of Cellular Physiology. 219(3), 634-641. [Abstract]
  • Johnson, M., Sharma, M., Jamieson, C., Henderson, J., Mok, M., Bendall, L., Henderson, B. (2009), Regulation of beta-catenin trafficking to the membrane in living cells. Cellular signalling. 21(0), 339-48. [Abstract]