Associate Professor Bing Yu

Associate Professor
Genetic Medicine, Central Clinical School

C39 - Royal Prince Alfred Hospital
The University of Sydney
NSW 2006 Australia

T: +61 2 9515 5016
F: +61 2 9550 4017

Research interests

A/Prof Bing Yu is a Molecular Geneticist and his research focuses on the identification of functional DNA variants involving gene-environment interaction and contributing to complex disease.


Motor neuron disease; Cardiovascular diseases; Genetic diseases; Molecular biology


2014 | 2013 | 2012 | 2011 | 2010 | 2009


  • Carlino, M., Haydu, L., Kakavand, H., Menzies, A., Hamilton, A., Yu, B., Ng, C., Cooper, W., Thompson, J., Kefford, R., O'Toole, S., Scolyer, R., Long, G. (2014), Correlation of BRAF and NRAS mutation status with outcome, site of distant metastasis and response to chemotherapy in metastatic melanoma. British Journal of Cancer. 111(2), 292-299. [Abstract]
  • Yu, B. (2014), Setting Up Next-Generation Sequencing in the Medical Laboratory. In: Methods in Molecular Biology: Vol 1168, Clinical Bioinformatics. (pp.195-206).United States: Humana Press, Inc..
  • O'Toole, S., Yu, B., Cooper, W. (2014), Molecular Diagnosis in Cytology and Its Place in the New Classification: A Practical Guide. The Journal of OncoPathology. 2(1), 63-73.
  • Fox, G., Sy, D., Nhung, N., Yu, B., Ellis, M., Van Hung, N., Cuong, N., Thi Lien, L., Marks, G., Saunders, B., Britton, W. (2014), Polymorphisms of SP110 Are Associated with both Pulmonary and Extra-Pulmonary Tuberculosis among the Vietnamese. PloS One. 9(7), e99496. [Abstract]


  • Ng, E., Lu, Y., Hambly, B., Jelinek, H., Yu, B., Matthews, S., McLachlan, C. (2013), Angiotensin-converting enzyme gene DD genotype is associated with increased systolic blood pressure in an Australian Rural Type 2 Diabetic Cohort. Hypertension Research. 36(4), 381-382. [Abstract]
  • Pamphlett, R., Cheong, P., Trent, R., Yu, B. (2013), Can ALS-Associated C9orf72 Repeat Expansions be Diagnosed on a Blood DNA Test Alone?. PloS One. 8(7), e70007. [Abstract]
  • Cooper, W., Yu, B., Yip, P., Ng, C., Lum, T., Farzin, M., Trent, R., Mercorella, B., Clarkson, A., Kohonen-Corish, M., Horvath, L., Kench, J., McCaughan, B., Gill, A., O'Toole, S. (2013), EGFR mutant-specific immunohistochemistry has high specificity and sensitivity for detecting targeted activating EGFR mutations in lung adenocarcinoma. Journal of Clinical Pathology. 66(9), 744-748. [Abstract]
  • Chan, K., O'Connell, R., Sullivan, D., Hoffmann, L., Rajamani, K., Whiting, M., Donoghoe, M., Vanhala, M., Hamer, A., Yu, B., Stocker, R., Ng, M., Keech, A. (2013), Plasma total bilirubin levels predict amputation events in type 2 diabetes mellitus: the fenofibrate intervention and event lowering in diabetes (field) study. Diabetologia. 56(4), 724-736. [Abstract]
  • Yip, P., Yu, B., Cooper, W., Selinger, C., Ng, C., Kennedy, C., Kohonen-Corish, M., McCaughan, B., Trent, R., Boyer, M., Kench, J., Horvath, L., O'Toole, S. (2013), Patterns of DNA Mutations and ALK Rearrangement in Resected Node Negative Lung Adenocarcinoma. Journal of Thoracic Oncology. 8(4), 408-414. [Abstract]
  • Yu, B. (2013), In silico interpretation of the splicing code and estimating the abundance of expressed mRNA isoforms. Human Mutation. 34(4), v. [Abstract]
  • Karim, R., O'Toole, S., Scolyer, R., Cooper, C., Chan, B., Selinger, C., Yu, B., Carmalt, H., Mak, C., Tse, G., Tan, P., Putti, T., Lee, C. (2013), Recent insights into the molecular pathogenesis of mammary phyllodes tumours. Journal of Clinical Pathology. 66, 496-505. [Abstract]


  • Pamphlett, R., Cheong, P., Trent, R., Yu, B. (2012), Transmission of C9orf72 hexanucleotide repeat expansions in sporadic amyotrophic lateral sclerosis: an Australian trio study. Neuroreport. 23(9), 556-559. [Abstract]
  • Pamphlett, R., Morahan, J., Luquin, N., Yu, B. (2012), An approach to finding brain-situated mutations in sporadic Parkinson's disease. Parkinsonism & related disorders. 18(1), 82-5. [Abstract]


  • Pamphlett, R., Morahan, J., Luquin, N., Yu, B. (2011), Looking for differences in copy number between blood and brain in sporadic amyotrophic lateral sclerosis. Muscle & nerve. 44(4), 492-8. [Abstract]
  • Yu, B., Fey, P., Kestin-Pilcher, K., Fedorov, A., Prakash, A., Chisholm, R., Wu, J. (2011), Spliceosomal genes in the D. discoideum genome: a comparison with those in H. sapiens, D. melanogaster, A. thaliana and S. cerevisiae. Protein & Cell. 2(5), 395-409. [Abstract]
  • Pamphlett, R., Morahan, J., Yu, B. (2011), Using case-parent trios to look for rare de novo genetic variants in adult-onset neurodegenerative diseases. Journal of Neuroscience Methods. 197(2), 297-301. [Abstract]
  • Sandhu, S., McKenzie, P., Yu, B., Chua, E. (2011), Phaeochromocytoma, Neurofibromatosis and Gastrointestinal stromal tumour: Just a random event?. Internal Medicine Journal. 41(2), 212-213.
  • Yu, B., Hinchcliffe, M. (2011), Methods in Molecular Biology: In Silico Tools for Gene Discovery. United States: Springer.
  • Yu, B., Zhang, C. (2011), In silico PCR analysis. In: Methods in Molecular Biology:In Silico Tools for Gene Discovery. (pp.91-107).United States: Springer.
  • Dong, C., Yu, B. (2011), Mutation Surveyor: An In Silico Tool for Sequencing Analysis. In: Methods in Molecular Biology:In Silico Tools for Gene Discovery. (pp.223-237).United States: Springer.


  • Luquin, N., Yu, B., Trent, R., Pamphlett, R. (2010), DHPLC can be used to detect low-level mutations in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis. 11(1-2), 76-82. [Abstract]
  • Yu, B., Trent, R. (2010), Genetics of Athletic Performance. In: Encyclopedia of Life Sciences. (pp.1-8).United Kingdom: John Wiley & Sons Ltd..
  • Xu, M., Bi, Y., Xu, Y., Yu, B., Huang, Y., Gu, L., Wu, Y., Zhu, X., Li, M., Wang, T., Song, A., Hou, J., Li, X., Ning, G. (2010), Combined effects of 19 common variations on type 2 diabetes in Chinese: results from two community-based studies. PloS One. 5(11), e14022. [Abstract]


  • Luquin, N., Yu, B., Saunderson, R., Trent, R., Pamphlett, R. (2009), Genetic variants in the promoter of TARDBP in sporadic amyotrophic lateral sclerosis. Neuromuscular Disorders. 19(10), 696-700. [Abstract]
  • Yu, B. (2009), Role of In Silico Tools in Gene Discovery. Molecular biotechnology. 41(0), 296-306. [Abstract]
  • Morahan, J., Yu, B., Trent, R., Pamphlett, R. (2009), A genome-wide analysis of brain DNA methylation identifies new candidate genes for sporadic amyotrophic lateral sclerosis. Amyotrophic lateral sclerosis. 10(5-6), 418-429. [Abstract]
  • Trent, R., Yu, B. (2009), The future of genetic research in exercise science and sports medicine. Medicine and Sport Science. 54, 187-195. [Abstract]