Associate Professor Deborah Marsh

Associate Professor & Research Only Academic Level D
Medicine, Northern Clinical School
Kolling Institute of Medical Research

E25 - Royal North Shore Hospital
The University of Sydney
NSW 2006 Australia

T: +61 2 9926 4760
F: +61 2 9926 8484
E:
W: Related website

Research interests

The molecular nature of endocrine tumorigenesis

PhD and Masters' project opportunities

Studies of a novel cancer gene with links to transcription
Ovarian cancer – understanding molecular events in advanced disease   +

+ indicates the opportunity is full and unavailable.

Current national competitive grants*

2011

Understanding endocrine tumorigenesis - opportunities for new diagnostics and therapies
Marsh D
Australian Research Council Future Fellowship ($813,192 over 4 years)

* Grants administered through the University of Sydney

Keywords

Gynaecological cancer; Cell biology; Women's health; Cancer; Genetics

International links

United States. (Boston University, MA) collaborating with Dr Muhammad Zaman, focussing on cell migration.
United States. (Van Andel Research Institute, Grand Rapids, MI) collaborating with Dr Bin Teh, focussing on the molecular nature of parathyroid tumorigenesis.
Sweden. (University Hospital Linkoping, Linkoping) collaborating with Professor Oliver Gimm, focussing on familial endocrine cancers and parathyroid tumorigenesis.

Publications

2013 | 2012 | 2011 | 2010 | 2009 | 2008

2013

   
  • Chung, L., Shibli, S., Moore, K., Elder, E., Boyle, F., Marsh, D., Baxter, R. (2013), Tissue biomarkers of breast cancer and their association with conventional pathologic features. British Journal of Cancer. 108(2), 351-360. [Abstract]

2012

   
  • Mertens-Walker, I., Baxter, R., Marsh, D. (2012), Gonadotropin signalling in epithelial ovarian cancer. Cancer Letters. 324(2), 152-159. [Abstract]
  • Paul, R., Elston, M., Gill, A., Marsh, D., Beer, I., Wolmarans, L., Conaglen, J., Meyer-Rochow, G. (2012), Hypercalcaemia due to parathyroid carcinoma presenting in the third trimester of pregnancy. Australian and New Zealand Journal of Obstetrics and Gynaecology. 52(2), 204-207. [Abstract]
  • Gribben, L., Baxter, R., Marsh, D. (2012), Insulin-like growth factor binding protein-3 inhibits migration of endometrial cancer cells. Cancer letters. 317(1), 41-8. [Abstract]
  • Hahn, M., Dickson, K., Jackson, S., Clarkson, A., Gill, A., Marsh, D. (2012), The tumor suppressor CDC73 interacts with the ring finger proteins RNF20 and RNF40 and is required for the maintenance of histone 2B monoubiquitination. Human molecular genetics. 21(3), 559-68. [Abstract]
  • Kan, C., Hahn, M., Gard, G., Maidens, J., Huh, J., Marsh, D., Howell, V. (2012), Elevated levels of circulating microRNA-200 family members correlate with serous epithelial ovarian cancer. BMC Cancer. 12, 627. [Abstract]

2011

   
  • Marsh, D., Trahair, T., Kirk, E. (2011), Mutant AKT1 in Proteus syndrome. The New England Journal of Medicine. , 2141-2142. [Abstract]
  • Lim, S., Elston, M., Gill, A., Marsh, D., Conaglen, J. (2011), Metastatic parathyroid carcinoma initially misdiagnosed as parathyroid adenoma: the role of parafibromin in increasing diagnostic accuracy. Internal Medicine Journal. 41(9), 695-699. [Abstract]
  • Lin, W., Martin, J., Marsh, D., Jack, M., Baxter, R. (2011), Involvement of insulin-like growth factor binding protein-3 in the effects of the histone deacetylase inhibitor MS-275 in hepatoma cells. The Journal of biological chemistry. 286(34), 29540-7. [Abstract]
  • Marsh, D., Gimm, O. (2011), Multiple endocrine neoplasia: types 1 and 2. Advances in Oto-Rhino-Laryngology. 70, 84-90. [Abstract]

2010

   
  • Bolitho, C., Hahn, M., Baxter, R., Marsh, D. (2010), The chemokine CXCL1 induces proliferation in epithelial ovarian cancer cells by transactivation of the epidermal growth factor receptor. Endocrine-related cancer. 17(4), 929-40. [Abstract]
  • Mertens-Walker, I., Bolitho, C., Baxter, R., Marsh, D. (2010), Gonadotropin-induced ovarian cancer cell migration and proliferation require extracellular signal-regulated kinase 1/2 activation regulated by calcium and protein kinase C{delta}. Endocrine-related cancer. 17(2), 335-49. [Abstract]
  • Hahn, M., Howell, V., Gill, A., Clarkson, A., Weaire-Buchanan, G., Robinson, B., Delbridge, L., Gimm, O., Schmitt, W., Teh, B., Marsh, D. (2010), CDC73/HRPT2 CpG island hypermethylation and mutation of 5'-untranslated sequence are uncommon mechanisms of silencing parafibromin in parathyroid tumors. Endocrine-related cancer. 17(1), 273-82. [Abstract]
  • Marsh, D., Howell, V. (2010), The Use of Denaturing High Performance Liquid Chromatography (DHPLC) for Mutation Scanning of Hereditary Cancer Genes. In: Methods in Molecular Biology: Cancer Susceptibility, Methods and Protocols. (pp.133-145).United States: Humana Press.

2009

   
  • Meyer-Rochow, G., Smith, J., Richardson, A., Marsh, D., Sidhu, S., Robinson, B., Benn, D. (2009), Denaturing High Performance Liquid Chromatography Detection of SDHB, SDHD, and VHL Germline Mutations in Pheochromocytoma. Journal of Surgical Research. 157(1), 55-62. [Abstract]
  • Hahn, M., McDonnell, J., Marsh, D. (2009), The effect of disease-associated HRPT2 mutations on splicing. Journal of Endocrinology. 201(3), 387-396. [Abstract]
  • Howell, V., Gill, A., Clarkson, A., Nelson, A., Dunne, R., Delbridge, L., Robinson, B., Teh, B., Gimm, O., Marsh, D. (2009), Accuracy of combined protein gene product 9.5 and parafibromin markers for immunohistochemical diagnosis of parathyroid carcinoma. The Journal of clinical endocrinology and metabolism. 94(2), 434-41. [Abstract]

2008

   
  • Marsh, D., Trahair, T., Martin, J., Chee, W., Walker, J., Kirk, E., Baxter, R., Marshall, G. (2008), Rapamycin treatment for a child with germline PTEN mutation. Nature clinical practice. Oncology. 5(6), 357-61. [Abstract]
  • Marsh, D., Zori, R. (2008), Cowden Syndrome. In: Encyclopedia of Cancer, Vol. 1. (pp.0).Germany: Springer.