Professor Jacob George

Professor of Gastroenterology & Hepatic Medicine
Medicine, Westmead Clinical School
Westmead Millennium Institute for Medical Research

C24 - Westmead Hospital
The University of Sydney
NSW 2006 Australia

T: +61 2 9845 7705
F: +61 2 9635 7582
E:

W: Related website

Research interests

Professor George undertakes basic research on non-alcoholic steatohepatitis (NASH) and hepatic fibrosis. He is also researching the molecular and cellular basis for disease progression in chronic hepatitis C. He has published seminal papers on the central role of transforming growth factor beta (TGF beta) in fibrogenesis.

Keywords

Cancer; Cell biology; Hepatology; Hepatitis

Publications

2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008

2014

   
  • Grebely, J., Page, K., Sacks-Davis, R., Schim van der Loeff, M., Rice, T., Bruneau, J., Morris, M., Hajarizadeh, B., Amin, J., Cox, A., Kim, A., McGovern, B., Schinkel, J., George, J., Shoukry, N., Lauer, G., Maher, L., Lloyd, A., Hellard, M., Dore, G., Prins, M. (2014), The effects of female sex, viral genotype, and IL28B genotype on spontaneous clearance of acute hepatitis C Virus infection. Hepatology. 59(1), 109-120. [Abstract]
  • Barrera, F., George, J. (2014), Prothrombotic factors and NAFLD: An additional link to cardiovascular risk?. Hepatology. 59, 16-18. [Abstract]

2013

   
  • Poustchi, H., Eslami, M., Ostovaneh, M., Modabbernia, A., Saeedian, F., Taslimi, S., George, J., Malekzadeh, R., Zamani, F. (2013), Transient elastography in hepatitis C virus-infected patients with beta-thalassemia for assessment of fibrosis. Hepatology Research. 43(12), 1276-1283. [Abstract]
  • Vongsuvanh, R., George, J., Qiao, L., Poorten, D. (2013), Visceral Adiposity In Gastrointestinal And Hepatic Carcinogenesis. Cancer Letters. 330(1), 1-10. [Abstract]
  • Kitson, M., Dore, G., George, J., Button, P., McCaughan, G., Crawford, D., Sievert, W., Weltman, M., Cheng, W., Roberts, S. (2013), Vitamin D status does not predict sustained virologic response or fibrosis stage in chronic hepatitis C genotype 1 infection. Journal of Hepatology. 58(3), 467-472. [Abstract]
  • Eslam, M., Booth, D., George, J., Ahlenstiel, G. (2013), Interaction of IFNL3 with insulin resistance, steatosis and lipid metabolism in chronic hepatitis C virus infection. World Journal of Gastroenterology. 19(41), 7055-7061. [Abstract]
  • Angulo, P., Bugianesi, E., Bjornsson, E., Charatcharoenwitthaya, P., Mills, P., Barrera, F., Haflidadottir, S., Day, C., George, J. (2013), Simple noninvasive systems predict long-term outcomes of patients with nonalcoholic fatty liver disease. Gastroenterology. 145(4), 782-789.e4. [Abstract]
  • van der Poorten, D., Samer, C., Ramezani-Moghadam, M., Coulter, S., Kacevska, M., Schrijnders, D., Wu, L., McLeod, D., Bugianesi, E., Komuta, M., Roskams, T., Liddle, C., Hebbard, L., George, J. (2013), Hepatic fat loss in advanced nash: Are alterations in serum adiponectin the cause?. Hepatology. 57(6), 2180-2188. [Abstract]
  • Kim, M., Lee, K., Iseli, T., Hoy, A., George, J., Grewal, T., Roufogalis, B. (2013), Compound K modulates fatty acid-induced lipid droplet formation and expression of proteins involved in lipid metabolism in hepatocytes. Liver International. 33, 1583-1593. [Abstract]
  • Wilson, G., Tian, A., Hebbard, L., Duan, W., George, J., Li, X., Qiao, L. (2013), Tumoricidal effects of the JAK inhibitor Ruxolitinib (INC424) on hepatocellular carcinoma in vitro. Cancer Letters. 341(2), 224-230. [Abstract]
  • Dong, Z., Su, L., Brymora, J., Bird, C., Xie, Q., George, J., Wang, J. (2013), Resistin mediates the hepatic stellate cell phenotype. World Journal of Gastroenterology. 19(28), 4475-4485. [Abstract]
  • Gélinas, J., Fabre, T., Willems, P., Leung, R., George, J., Willems, B., Bruneau, J., Shoukry, N. (2013), IL28B SNP screening and distribution in the French Canadian population using a rapid PCR-based test. Immunogenetics. 65(6), 397-403. [Abstract]
  • Wilson, G., Hu, Z., Duan, W., Tian, A., Wang, X., McCleod, D., Lam, V., George, J., Qiao, L. (2013), Efficacy of using cancer stem cell markers in isolating and characterising liver cancer stem cells. Stem Cells and Development. 22(19), 2655-2664. [Abstract]
  • Suppiah, V., Armstrong, N., O'Connor, K., Berg, T., Weltman, M., Abate, M., Spengler, U., Bassendine, M., Dore, G., Irving, W., Powell, E., Nattermann, J., Mueller, T., Riordan, S., Stewart, G., George, J., Booth, D., Ahlenstiel, G., Michalk, M., Malik, B., McClure, P., Smith, S., Sheridan, D., Snape, E., Fragomeli, V., Norris, R., How-Chow, D., Jonsson, J., Barrie, H., Stelzer-Braid, S., Fletcher, S., Applegate, T., Grebely, J., Matthews, G., Bharadwaj, M., Smedile, A. (2013), CCR5-Δ32 genotype does not improve predictive value of IL28B polymorphisms for treatment response in chronic HCV infection. Genes and Immunity. 14(5), 286-290. [Abstract]
  • Foster, G., Zeuzem, S., Pianko, S., Sarin, S., Piratvisuth, T., Shah, S., Andreone, P., Sood, A., Chuang, W., Lee, C., George, J., Gould, M., Flisiak, R., Jacobson, I., Komolmit, P., Thongsawat, S., Tanwandee, T., Rasenack, J., Sola, R., Messina, I., Yin, Y., Cammarata, S., Feutren, G., Brown, K. (2013), Decline in pulmonary function during chronic hepatitis C virus therapy with modified interferon alfa and ribavirin. Journal of Viral Hepatitis. 20(4), e115-123. [Abstract]
  • Hu, L., George, J., Wang, J. (2013), Current concepts on the role of nitric oxide in portal hypertension. World Journal of Gastroenterology. 19(11), 1707-1717. [Abstract]
  • Petta, S., Rosso, C., Leung, R., Abate, M., Booth, D., Salomone, F., Gambino, R., Rizzetto, M., Caviglia, P., Smedile, A., Grimaudo, S., Cammà, C., Craxì, A., George, J., Bugianesi, E. (2013), Effects of IL28B rs12979860 CC genotype on metabolic profile and sustained virologic response in patients with genotype 1 chronic hepatitis C. Clinical Gastroenterology and Hepatology. 11(3), 311-317.e1. [Abstract]
  • Sublette, V., Douglas, M., McCaffery, K., George, J., Perry, K. (2013), Psychological, lifestyle and social predictors of hepatitis c treatment response: a systematic review. Liver International. 33(6), 894-903. [Abstract]
  • Fahrtash-Bahin, F., Kariyawasam, V., Gray, T., Byth, K., George, J., Douglas, M. (2013), Australian tertiary care outcomes of entecavir monotherapy in treatment naive patients with chronic hepatitis B. World Journal of Gastroenterology. 19(5), 721-726. [Abstract]
  • Carulli, L., Maurantonio, M., Hebbard, L., Baldelli, E., Loria, P., Jacob, G. (2013), Classical and Innovative Insulin Sensitizing Drugs for the Prevention and Treatment of NAFLD. Current Pharmaceutical Design. 19(29), 5280-5296. [Abstract]
  • Booth, D., George, J. (2013), Loss of function of the new interferon IFN-λ4 may confer protection from hepatitis C. Nature Genetics. 45(2), 119-120. [Abstract]
  • Grebely, J., Feld, J., Applegate, T., Matthews, G., Hellard, M., Sherker, A., Petoumenos, K., Zang, G., Shaw, I., Yeung, B., George, J., Teutsch, S., Kaldor, J., Cherepanov, V., Bruneau, J., Shoukry, N., Lloyd, A., Dore, G. (2013), Plasma interferon-gamma-inducible protein-10 (ip-10) levels during acute hepatitis c virus infection. Hepatology. 57(6), 2124-2134. [Abstract]
  • Hashemi, S., van der Poorten, D., Barrera, F., Bandara, P., Lux, O., Kench, J., George, J. (2013), Oxidative stress is closely associated with insulin resistance in genotypes 1 and 3 chronic hepatitis C. Hepatology International. 7(2), 516-523.
  • Robotin, M., Patton, Y., George, J. (2013), Getting it right: the impact of a continuing medical education program on hepatitis B knowledge of Australian primary care providers. International Journal of General Medicine. 6, 115-122. [Abstract]
  • Fischer, J., Böhm, S., George, J., Sarrazin, C., Berg, T. (2013), Impact of cohort size and host factors on combined analysis of interleukin 28B rs12979860 and rs8099917 in hepatitis c virus infection. Hepatology. , 416-417. [Abstract]
  • Barrera, F., George, J. (2013), Non-alcoholic fatty liver disease: More than just ectopic fat accumulation. Drug Discovery Today: Disease Mechanisms. 10:1-2, e47-e54.
  • Mahady, S., George, J. (2013), The Future Liver of the Asia Pacific: Fatter and Firmer from More Fructose and Fortune?. Journal of Clinical and Experimental Hepatology. 3:2, 106-113.

2012

   
  • Booth, D., Ahlenstiel, G., George, J. (2012), Pharmacogenomics of hepatitis C infections: personalizing therapy. Genome Medicine. 4(12), 99. [Abstract]
  • Robotin, M., Patton, Y., Kansil, M., Penman, A., George, J. (2012), Cost of treating chronic hepatitis B: Comparison of current treatment guidelines. World Journal of Gastroenterology. 18(42), 6106-6113. [Abstract]
  • Patin, E., Kutalik, Z., Guergnon, J., Bibert, S., Nalpas, B., Jouanguy, E., Munteanu, M., Bousquet, L., Argiro, L., Halfon, P., Boland, A., Müllhaupt, B., Semela, D., Dufour, J., Heim, M., Moradpour, D., Cerny, A., Malinverni, R., Hirsch, H., Martinetti, G., Suppiah, V., Stewart, G., Booth, D., George, J., Casanova, J., Bréchot, C., Rice, C., Talal, A., Jacobson, I., Bourlière, M., Theodorou, I., Poynard, T., Negro, F., Pol, S., Bochud, P., Abel, L. (2012), Genome-wide association study identifies variants associated with progression of liver fibrosis from HCV infection. Gastroenterology. 143(5), 1244-52.e1-12. [Abstract]
  • Qiao, L., George, J., Li, Y., Yan, X. (2012), Molecular Aspects of Hepatocellular Carcinoma. United States: Bentham Science Publishers Ltd..
  • Walker, S., George, J., Hebbard, L. (2012), Animal Models of Hepatocellular Carcinoma. In: Molecular Aspects of Hepatocellular Carcinoma. (pp.116-128).United States: Bentham Science Publishers Ltd..
  • Pianko, S., Zeuzem, S., Chuang, W., Foster, G., Sarin, S., Flisiak, R., Lee, C., Andreone, P., Piratvisuth, T., Shah, S., Sood, A., George, J., Gould, M., Komolmit, P., Thongsawat, S., Tanwandee, T., Rasenack, J., Li, Y., Pang, M., Yin, Y., Feutren, G., Jacobson, I. (2012), Randomized trial of albinterferon alfa-2b every 4 weeks for chronic hepatitis C virus genotype 2/3. Journal of Viral Hepatitis. 19(9), 623-634. [Abstract]
  • Rahman, W., Huang, P., Belov, L., Chrisp, J., Christopherson, R., Stapelberg, P., Warner, F., George, J., Bowen, D., Strasser, S., Koorey, D., Sharland, A., McCaughan, G., Shackel, N. (2012), Analysis of human liver disease using a cluster of differentiation (CD) antibody microarray. Liver International. 32(10), 1527-1534. [Abstract]
  • Vongsuvanh, R., George, J., McLeod, D., van der Poorten, D. (2012), Visceral adiposity index is not a predictor of liver histology in patients with non-alcoholic fatty liver disease. Journal of Hepatology. 57(2), 392-398. [Abstract]
  • Mahady, S., George, J. (2012), Management of nonalcoholic steatohepatitis: an evidence-based approach. Clinics in Liver Disease. 16(3), 631-645. [Abstract]
  • Parker, H., Johnson, N., George, J. (2012), Reply to: "The optimal dose of omega-3 supplementation for non-alcoholic fatty liver disease". Journal of Hepatology. , 469-470. [Abstract]
  • Nguyen, V., George, J., van der Poorten, D. (2012), A maxillary mass in a HBV-cirrhotic patient. Liver International. 32(6), 988. [Abstract]
  • Keating, S., Hackett, D., George, J., Johnson, N. (2012), Exercise and non-alcoholic fatty liver disease: A systematic review and meta-analysis. Journal of Hepatology. 57(1), 157-166. [Abstract]
  • Mahady, S., Wong, G., Craig, J., George, J. (2012), Pioglitazone and vitamin E for non alcoholic steatohepatitis: A cost utility analysis. Hepatology. 56(6), 2172-2179. [Abstract]
  • Gidding, H., Law, M., Amin, J., Ostapowicz, G., Weltman, M., Macdonald, G., Sasadeusz, J., Haber, P., George, J., Dore, G. (2012), Hepatitis C treatment outcomes in Australian clinics. Medical Journal of Australia. 196(10), 633-637. [Abstract]
  • Fischer, J., Böhm, S., Scholz, M., Müller, T., Witt, H., George, J., Sarrazin, C., Susser, S., Schott, E., Suppiah, V., Booth, D., Stewart, G., van Bömmel, F., Brodzinski, A., Fülöp, B., Migaud, P., Berg, T. (2012), Combined effects of different interleukin-28B gene variants on the outcome of dual combination therapy in chronic hepatitis C virus type 1 infection. Hepatology. 55(6), 1700-1710. [Abstract]
  • Poutschi, H., George, J. (2012), Reply. Hepatology. , 2039-2040. [Abstract]
  • Grebely, J., Hellard, M., Applegate, T., Petoumenos, K., Yeung, B., Feld, J., Rawlinson, W., Lloyd, A., George, J., Kaldor, J., Dore, G., Matthews, G. (2012), Virological responses during treatment for recent hepatitis C virus: Potential benefit for ribavirin use in HCV/HIV co-infection. AIDS. 26(13), 1653-1661. [Abstract]
  • Johnson, N., van Overbeek, D., Chapman, P., Thompson, M., Sachinwalla, T., George, J. (2012), Effect of prolonged exercise and pre-exercise dietary manipulation on hepatic triglycerides in trained men. European Journal of Applied Physiology. 112(5), 1817-1825. [Abstract]
  • Thein, H., Walter, S., Gidding, H., Amin, J., Law, M., George, J., Dore, G. (2012), Survival after diagnosis of hepatocellular carcinoma and potential impact of treatment in a hepatitis B or C infected cohort. Hepatology Research. 42(12), 1175-1186. [Abstract]
  • Parker, H., Johnson, N., Burdon, C., Cohn, J., O'Connor, H., George, J. (2012), Omega-3 Supplementation and Non-Alcoholic Fatty Liver Disease: A Systematic Review and Meta-analysis. Journal of Hepatology. 56(4), 944-951. [Abstract]
  • Johnson, N., Keating, S., George, J. (2012), Exercise and the liver: implications for therapy in fatty liver disorders. Seminars in Liver Disease. 32(1), 65-79. [Abstract]
  • Pattullo, V., George, J. (2012), The Problem of Insulin Resistance and its Effect on Therapy. In: Advanced Therapy for Hepatitis C. (pp.169-176).United Kingdom: Blackwell Publishing Ltd.
  • Ahlenstiel, G., Booth, D., George, J. (2012), Will IL28B polymorphisms remain relevant to direct-acting antiviral treatment paradigms?. Antiviral Therapy. 17(6 Pt B), 1163-1170. [Abstract]

2011

   
  • Mahady, S., Webster, A., Walker, S., Sanyal, A., George, J. (2011), The role of thiazolidinediones in non-alcoholic steatohepatitis- a systematic review and meta analysis. Journal of Hepatology. 55(6), 1383-1390. [Abstract]
  • Poustchi, H., Farrell, G., Strasser, S., Lee, A., McCaughan, G., George, J. (2011), Feasibility of conducting a randomised control trial for liver cancer screening: Is a randomized controlled trial for liver cancer screening feasible or still needed?. Hepatology. 54(6), 1998-2004. [Abstract]
  • Walter, S., Thein, H., Gidding, H., Amin, J., Law, M., George, J., Dore, G. (2011), Risk factors for hepatocellular carcinoma in a cohort infected with hepatitis B or hepatitis C. Journal of Gastroenterology and Hepatology. 26(12), 1757-1764. [Abstract]
  • Bhala, N., Angulo, P., van der Poorten, D., Lee, E., Hui, J., Saracco, G., Adams, L., Charatcharoenwitthaya, P., Topping, J., Bugianesi, E., Day, C., George, J. (2011), The natural history of nonalcoholic fatty liver disease with advanced fibrosis or cirrhosis: An international collaborative study. Hepatology. 54(4), 1208-1216. [Abstract]
  • Adams, L., George, J., Bugianesi, E., Rossi, E., De Boer, W., van der Poorten, D., Ching, H., Bulsara, M., Jeffrey, G. (2011), Complex non-invasive fibrosis models are more accurate than simple models in non-alcoholic fatty liver disease. Journal of Gastroenterology and Hepatology. 26(10), 1536-1543. [Abstract]
  • Park, G., Wiseman, E., George, J., Katelaris, P., Seow, F., Fung, C., Ngu, M. (2011), Non-invasive Estimation of Liver Fibrosis in Non-alcoholic Fatty Liver Disease Using the (13) C-Caffeine Breath Test. Journal of Gastroenterology and Hepatology. 26(9), 1411-1416. [Abstract]
  • Suppiah, V., Gaudieri, S., Armstrong, N., O'Connor, K., Berg, T., Weltman, M., Abate, M., Spengler, U., Bassendine, M., Dore, G., Irving, W., Powell, E., Hellard, M., Riordan, S., Matthews, G., Sheridan, D., Nattermann, J., Smedile, A., Müller, T., Hammond, E., Dunn, D., Negro, F., Bochud, P., Mallal, S., Ahlenstiel, G., Stewart, G., George, J., Booth, D. (2011), IL28B, HLA-C, and KIR Variants Additively Predict Response to Therapy in Chronic Hepatitis C Virus Infection in a European Cohort: A Cross-Sectional Study. PLoS Medicine. 8(9), e1001092. [Abstract]
  • Raftopoulos, S., George, J., Bourliere, M., Rossi, E., de Boer, W., Jeffrey, G., Bulsara, M., Speers, D., Macquillan, G., Ching, H., Kontorinis, N., Cheng, W., Flexman, J., Fermoyle, S., Rigby, P., Walsh, L., McLeod, D., Adams, L. (2011), Comparison of noninvasive models of fibrosis in chronic hepatitis B. Hepatology International. 6(2), 457-467. [Abstract]
  • Thein, H., Walter, S., Gidding, H., Amin, J., Law, M., George, J., Dore, G. (2011), Trends in incidence of hepatocellular carcinoma after diagnosis of hepatitis B or C infection: a population-based cohort study, 1992-2007. Journal of Viral Hepatitis. 18(7), e232-e241. [Abstract]
  • Jacobson, I., McHutchison, J., Dusheiko, G., Di Bisceglie, A., Reddy, K., Bzowej, N., Marcellin, P., Muir, A., Ferenci, P., Flisiak, R., George, J., Rizzetto, M., Shouval, D., Sola, R., Terg, R., Yoshida, E., Adda, N., Bengtsson, L., Sankoh, A., Kieffer, T., George, S., Kauffman, R., Zeuzem, S. (2011), Telaprevir for previously untreated chronic hepatitis C virus infection. New England Journal of Medicine. 364(25), 2405-2416. [Abstract]
  • Walter, S., Thein, H., Amin, J., Gidding, H., Ward, K., Law, M., George, J., Dore, G. (2011), Trends in mortality after diagnosis of hepatitis B or C infection: 1992-2006. Journal of Hepatology. 54(5), 879-886. [Abstract]
  • Liu, Y., Brymora, J., Zhang, H., Smith, B., Ramezani-Moghadam, M., George, J., Wang, J. (2011), Leptin and Acetaldehyde Synergistically Promotes αSMA Expression in Hepatic Stellate Cells by an Interleukin 6-Dependent Mechanism. Alcoholism, Clinical and Experimental Research. 35(5), 921-928. [Abstract]
  • Gidding, H., Law, M., Amin, J., Macdonald, G., Sasadeusz, J., Jones, T., Strasser, S., George, J., Dore, G. (2011), Predictors of deferral of treatment for hepatitis C infection in Australian clinics. Medical Journal of Australia. 194(8), 398-402. [Abstract]
  • Pattullo, V., Douglas, M., George, J. (2011), Organelle dysfunction in hepatitis C virus-associated steatosis: anything to learn from nonalcoholic steatohepatitis?. Expert Review of Gastroenterology & Hepatology. 5(2), 265-277. [Abstract]
  • Patterson, S., George, J., Strasser, S., Lee, A., Sievert, W., Nicoll, A., Desmond, P., Roberts, S., Locarnini, S., Bowden, S., Angus, P. (2011), Tenofovir disoproxil fumarate rescue therapy following failure of both lamivudine and adefovir dipivoxil in chronic hepatitis B. Gut. 60(2), 247-254. [Abstract]
  • Poustchi, H., George, J., Esmaili, S., Esna-Ashari, F., Ardalan, G., Sepanlou, S., Alavian, S. (2011), Gender differences in healthy ranges for serum alanine aminotransferase levels in adolescence. PLoS One. 6(6), e21178. [Abstract]
  • Hebbard, L., George, J. (2011), Animal models of nonalcoholic fatty liver disease. Nature Reviews. Gastroenterology & Hepatology. 8(1), 35-44. [Abstract]
  • Ahlenstiel, G., Booth, D., George, J. (2011), Clinical significance of IL28B gene variation in hepatitis C virus infection. Hot Topics in Viral Hepatitis. .(20), 17-24.
  • Smith, K., Suppiah, V., O'Connor, K., Berg, T., Weltman, M., Abate, M., Spengler, U., Bassendine, M., Matthews, G., Irving, W., Powell, E., Riordan, S., Ahlenstiel, G., Stewart, G., Bahlo, M., George, J., Booth, D. (2011), Identification of improved IL28B SNPs and haplotypes for prediction of drug response in treatment of hepatitis C using massively parallel sequencing in a cross-sectional European cohort. Genome Medicine. 3(8), 57. [Abstract]

2010

   
  • Grebely, J., Petoumenos, K., Hellard, M., Matthews, G., Suppiah, V., Applegate, T., Yeung, B., Marks, P., Rawlinson, W., Lloyd, A., Booth, D., Kaldor, J., George, J., Dore, G. (2010), Potential role for Interleukin-28B genotype in treatment decision-making in recent hepatitis C virus infection. Hepatology. 52(4), 1216-1224. [Abstract]
  • Ahlenstiel, G., Booth, D., George, J. (2010), IL28B in hepatitis C virus infection: translating pharmacogenomics into clinical practice. Journal of gastroenterology. 45(9), 903-10. [Abstract]
  • Johnson, N., George, J. (2010), Fitness versus fatness: Moving beyond weight loss in nonalcoholic fatty liver disease. Hepatology (Baltimore, Md.). 52(1), 370-81. [Abstract]
  • Hebbard, L., George, J. (2010), The chicken or the egg: adipocytes and hepatic insulin resistance. Hepatology. 51(3), 1076-1079. [Abstract]
  • Milner, K., van der Poorten, D., Trenell, M., Jenkins, A., Xu, A., Smythe, G., Dore, G., Zekry, A., Weltman, M., Fragomeli, V., George, J., Chisholm, D. (2010), Chronic Hepatitis C is Associated with Peripheral rather than Hepatic Insulin Resistance. Gastroenterology. 138(3), 932-41.e1-3. [Abstract]
  • Bhala, N., Usherwood, T., George, J. (2010), Nichtalkoholische Fettlebererkrankung [Non-alcoholic fatty liver]. Praxis. 99(3), 187-189. [Abstract]
  • Johnson, N., George, J. (2010), An Active Part in Treating Liver Disease. Exercise In Medical Conditions: Exercise And Non-Alcoholic Fatty Liver Disease. SportEx Health. 25, 18-20.
  • Mahady, S., George, J. (2010), How to Treat: Hepatitis C infection. Australian Doctor. Feb 2010, 1-6.
  • van der Poorten, D., Shahidi, M., Tay, E., Sesha, J., Tran, K., McLeod, D., Milliken, J., Ho, V., Hebbard, L., Douglas, M., George, J. (2010), Hepatitis C virus induces the cannabinoid receptor 1. PloS One. 5(9), pii: e1284. [Abstract]
  • Robotin, M., Kansil, M., George, J., Howard, K., Tipper, S., Levy, M., Phung, N., Penman, A. (2010), Using a population-based approach to prevent hepatocellular cancer in New South Wales, Australia: effects on health services utilisation. BMC Health Services Research. 10, 215. [Abstract]
  • Pattullo, V., George, J. (2010), Managing the Patient with Chronic Viral Hepatitis Receiving Chemotherapy. In: When Cancer Crosses Disciplines: A Physician's Handbook. (pp.813-832).London, UK: Imperial College Press.

2009

   
  • Johnson, N., Sachinwalla, T., Walton, D., Smith, K., Armstrong, A., Thompson, M., George, J. (2009), Aerobic exercise training reduces hepatic and visceral lipids in obese individuals without weight loss. Hepatology (Baltimore, Md.). 50(0), 1105-12. [Abstract]
  • Suppiah, V., Moldovan, M., Ahlenstiel, G., Berg, T., Weltman, M., Abate, M., Bassendine, M., Spengler, U., Dore, G., Powell, E., Riordan, S., Sheridan, D., Smedile, A., Fragomeli, V., Müller, T., Bahlo, M., Stewart, G., Booth, D., George, J. (2009), IL28B is associated with response to chronic hepatitis C interferon-alpha and ribavirin therapy. Nature Genetics. 41(10), 1100-1104. [Abstract]
  • Douglas, M., George, J. (2009), Molecular mechanisms of insulin resistance in chronic hepatitis C. World Journal of Gastroenterology. 15(35), 4356-4364. [Abstract]
  • van Hazel, G., Pavlakis, N., Goldstein, D., Olver, I., Tapner, M., Price, D., Bower, G., Briggs, G., Rossleigh, M., Taylor, D., George, J. (2009), Treatment of Fluorouracil-Refractory Patients With Liver Metastases From Colorectal Cancer by Using Yttrium-90 Resin Microspheres Plus Concomitant Systemic Irinotecan Chemotherapy. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 27(25), 4089-95. [Abstract]
  • Milner, K., Chisholm, D., George, J. (2009), The many faces of hepatitis C: liver disease and type 2 diabetes. Hepatology. 50, 668-670. [Abstract]
  • Wang, J., Leclercq, I., Brymora, J., Xu, N., Ramezani-Moghadam, M., London, R., Brigstock, D., George, J. (2009), Kupffer Cells Mediate Leptin-Induced Liver Fibrosis. Gastroenterology. 137(2), 713-23. [Abstract]
  • Phung, N., Pera, N., Farrell, G., Leclercq, I., Hou, J., George, J. (2009), Pro-oxidant-mediated hepatic fibrosis and effects of antioxidant intervention in murine dietary steatohepatitis. International journal of molecular medicine. 24(2), 171-180. [Abstract]
  • St George, A., Bauman, A., Johnston, A., Farrell, G., Chey, T., George, J. (2009), Independent effects of physical activity in patients with nonalcoholic fatty liver disease. Hepatology. 50(1), 68-76. [Abstract]
  • Milner, K., van der Poorten, D., Xu, A., Bugianesi, E., Kench, J., Lam, K., Chisholm, D., George, J. (2009), Adipocyte fatty acid binding protein levels relate to inflammation and fibrosis in nonalcoholic fatty liver disease. Hepatology. 49(6), 1926-1934. [Abstract]
  • Robotin, M., Kansil, M., Howard, K., George, J., Tipper, S., Dore, G., Levy, M., Penman, A. (2009), Antiviral therapy for hepatitis B-related liver cancer prevention is more cost-effective than cancer screening. Journal of Hepatology. 50(5), 990-998. [Abstract]
  • Smith, B., George, J. (2009), Adipocyte-hepatocyte crosstalk and the pathogenesis of nonalcoholic fatty liver disease. Hepatology. 49(5), 1765-1767. [Abstract]
  • St George, A., Bauman, A., Johnston, A., Farrell, G., Chey, T., George, J. (2009), Effect of a lifestyle intervention in patients with abnormal liver enzymes and metabolic risk factors. Journal of gastroenterology and hepatology. 24(0), 399-407. [Abstract]
  • Booth, M., Dobbins, T., Aitken, R., Denney-Wilson, E., Hardy, L., Okely, A., George, J., Sullivan, D., Cowell, C. (2009), Costs of managing conditions associated with obesity among Australian teenagers. Journal of paediatrics and child health. 45(0), 448-56. [Abstract]
  • van der Poorten, D., Milner, K., George, J. (2009), Effect of adipokines on liver disease in females. In: Female Hepatology: Impact of female sex against progression of liver disease. (pp.191-212).United States: Research Signpost.
  • George, J., Robotin, M. (2009), Overview: Hepatocellular Carcinoma. Cancer Forum. 33, 80-87.
  • Bhala, N., Usherwood, T., George, J. (2009), Non-alcoholic fatty liver disease. BMJ (Clinical research ed.). 339, b2474. [Abstract]

2008

   
  • Booth, M., George, J., Denney-Wilson, E., Okely, A., Hardy, L., Aitken, R., Dobbins, T. (2008), The population prevalence of adverse concentrations and associations with adiposity of liver tests among Australian adolescents. Journal of paediatrics and child health. 44(12), 686-91. [Abstract]
  • van der Poorten, D., George, J. (2008), Disease-specific mechanisms of fibrosis: hepatitis C virus and nonalcoholic steatohepatitis. Clinics in Liver Disease. 12(4), 805-824. [Abstract]
  • Poorten, D., George, J. (2008), Nonalcoholic steatohepatitis is frequently acompanied by metabolic diseases: Reply to the Editor. Hepatology. 48(5), 1729. [Abstract]
  • George, J., Denney-Wilson, E., Okely, A., Hardy, L., Aitken, R. (2008), The population distributions, upper normal limits and correlations between liver tests among Australian adolescents. Journal of Paediatrics and Child Health. 44(10), 579-585. [Abstract]
  • Cua, I., Hui, J., Kench, J., George, J. (2008), Genotype-specific interactions of insulin resistance, steatosis, and fibrosis in chronic hepatitis C. Hepatology (Baltimore, Md.). 48(3), 723-31. [Abstract]
  • van der Poorten, D., Milner, K., Hui, J., Hodge, A., Trenell, M., Kench, J., London, R., Peduto, T., Chisholm, D., George, J. (2008), Visceral fat: A key mediator of steatohepatitis in metabolic liver disease. Hepatology (Baltimore, Md.). 48(2), 449-57. [Abstract]
  • Johnson, N., Sachinwalla, T., George, J. (2008), In Vitro Proton Magnetic Resonance Spectroscopy of Liver Tissue Informs In Vivo Hepatic Proton Magnetic Resonance Spectroscopy Studies. Reply to the Editor. Hepatology. 48(3), 1016-1017. [Abstract]
  • Yan, K., Guirgis, M., Dinh, T., George, J., Dev, A., Lee, A., Zekry, A. (2008), Treatment responses in Asians and Caucasians with chronic hepatitis C infection. World Journal of Gastroenterology. 14(21), 3416-3420. [Abstract]
  • van der Poorten, D., Kenny, D., George, J. (2008), Prevalence of and risk factors for hepatitis C in Aboriginal and non-Aboriginal adolescent offenders. The Medical Journal of Australia. 188(10), 610-614. [Abstract]
  • Johnson, N., Walton, D., Sachinwalla, T., Thompson, C., Smith, K., Ruell, P., Stannard, S., George, J. (2008), Noninvasive assessment of hepatic lipid composition: Advancing understanding and management of fatty liver disorders. Hepatology. 47(5), 1513-1523. [Abstract]
  • Robotin, M., George, J., Supramaniam, R., Sitas, F., Penman, A. (2008), Preventing primary liver cancer: how well are we faring towards a national hepatitis B strategy?. The Medical Journal of Australia. 188(6), 363-365. [Abstract]
  • George, J. (2008), Evaluating abnormal liver tests. In: Gastroenterology and Hepatology: A Clinical Handbook. (pp.316-326).Australia: Elsevier Australia.
  • Wang, J., Brymora, J., George, J. (2008), Roles of adipokines in liver injury and fibrosis. Expert Review of Gastroenterology and Hepatology. 2(1), 47-57.
  • Poustchi, H., Mohamadkhani, A., Bowden, S., Montazeri, G., Ayres, A., Revill, P., Farrell, G., Locarnini, S., George, J., Malekzadeh, R. (2008), Clinical significance of precore and core promoter mutations in genotype D hepatitis B-related chronic liver disease. Journal of Viral Hepatitis. 15(10), 753-760. [Abstract]
  • George, J., Liddle, C. (2008), Nonalcoholic fatty liver disease: pathogenesis and potential for nuclear receptors as therapeutic targets. Molecular Pharmaceutics. 5(1), 49-59. [Abstract]
  • Poustchi, H., Negro, F., Hui, J., Cua, I., Brandt, L., Kench, J., George, J. (2008), Insulin resistance and response to therapy in patients infected with chronic hepatitis C virus genotypes 2 and 3. Journal of hepatology. 48(1), 28-34. [Abstract]
  • Cua, I., George, J. (2008), Insulin resistance, adipocytokines and HCV infection: A missing link?. Hepatology. , 760-761.