Dr Jeff Holst

Research Fellow
Medicine, Central Clinical School
Centenary Institute of Cancer Medicine & Cell Biology

C39 - Royal Prince Alfred Hospital
The University of Sydney
NSW 2006 Australia

T: +61 2 9565 6172
F: +61 2 9565 6101
E:

W: Related website

PhD and Masters' project opportunities

Defining the molecular role of nutrition in melanoma, breast and prostate cancer   +

+ indicates the opportunity is full and unavailable.

Publications

2014 | 2013 | 2012 | 2011 | 2010 | 2008

2014

   
  • Wang, Q., Beaumont, K., Otte, N., Font, J., Bailey, C., van Geldermalsen, M., Sharp, D., Tiffen, J., Ryan, R., Jormakka, M., Haass, N., Rasko, J., Holst, J. (2014), Targeting glutamine transport to suppress melanoma cell growth. International Journal of Cancer. 135(5), 1060-1671. [Abstract]
  • Wong, J., Ritchie, W., Gao, D., Lau, K., Gonzalez, M., Choudhary, A., Taft, R., Rasko, J., Holst, J. (2014), Identification of nuclear-enriched miRNAs during mouse granulopoiesis. Journal of Hematology & Oncology. 7(1), 42. [Abstract]

2013

   
  • Khoo, T., Xiros, N., Guan, F., Orellana, D., Holst, J., Joshua, D., Rasko, J. (2013), Performance evaluation of the Abbott CELL-DYN Emerald for use as a bench-top analyzer in a research setting. International Journal of Laboratory Hematology. 35(4), 447-456. [Abstract]
  • Wang, Q., Tiffen, J., Bailey, C., Lehman, M., Ritchie, W., Fazli, L., Metierre, C., Feng, Y., Li, E., Gleave, M., Buchanan, G., Nelson, C., Rasko, J., Holst, J. (2013), Targeting Amino Acid Transport in Metastatic Castration-Resistant Prostate Cancer: Effects on Cell Cycle, Cell Growth, and Tumor Development. Journal of the National Cancer Institute. 105(19), 1463-1473. [Abstract]
  • Wong, J., Ritchie, W., Ebner, O., Selbach, M., Wong, J., Huang, Y., Gao, D., Pinello, N., Gonzalez, M., Baidya, K., Thoeng, A., Khoo, T., Bailey, C., Holst, J., Rasko, J. (2013), Orchestrated intron retention regulates normal granulocyte differentiation. Cell. 154(3), 583-595. [Abstract]
  • Holst, J. (2013), Letter to the Editor. International Journal of Pharmaceutics. , 393. [Abstract]
  • Tiffen, J., Bailey, C., Marshall, A., Metierre, C., Feng, Y., Wang, Q., Watson, S., Holst, J., Rasko, J. (2013), The cancer-testis antigen BORIS phenocopies the tumor suppressor CTCF in normal and neoplastic cells. International Journal of Cancer. 133(7), 1603-1613. [Abstract]

2012

   
  • de Bock, C., Ardjmand, A., Molloy, T., Bone, S., Johnstone, D., Campbell, D., Shipman, K., Yeadon, T., Holst, J., Spanevello, M., Nelmes, G., Catchpoole, D., Lincz, L., Boyd, A., Burns, G., Thorne, R. (2012), The Fat1 cadherin is overexpressed and an independent prognostic factor for survival in paired diagnosis-relapse samples of precursor B-cell acute lymphoblastic leukemia. Leukemia. 26(5), 918-926. [Abstract]

2011

   
  • Wang, Q., Bailey, C., Ng, C., Tiffen, J., Thoeng, A., Minhas, V., Lehman, M., Hendy, S., Buchanan, G., Nelson, C., Rasko, J., Holst, J. (2011), Androgen receptor and nutrient signaling pathways coordinate the demand for increased amino acid transport during prostate cancer progression. Cancer research. 71(24), 7525-36. [Abstract]
  • Bröer, A., Juelich, T., Vanslambrouck, J., Tietze, N., Solomon, P., Holst, J., Bailey, C., Rasko, J., Bröer, S. (2011), Impaired Nutrient Signaling and Body Weight Control in a Na+ Neutral Amino Acid Cotransporter (Slc6a19)-deficient Mouse. The Journal of Biological Chemistry. 286(30), 26638-26651. [Abstract]

2010

   
  • Kranias, G., Watt, L., Carpenter, H., Holst, J., Ludowyke, R., Strack, S., Sim, A., Verrills, N. (2010), Protein phosphatase 2A carboxymethylation and regulatory B subunits differentially regulate mast cell degranulation. Cellular Signalling. 22(12), 1882-1890. [Abstract]
  • Holst, J., Watson, S., Lord, M., Eamegdool, S., Bax, D., Nivison-Smith, L., Kondyurin, A., Ma, L., Oberhauser, A., Weiss, A., Rasko, J. (2010), Substrate elasticity provides mechanical signals for the expansion of hemopoietic stem and progenitor cells. Nature biotechnology. 28(10), 1123-8. [Abstract]
  • Taft, R., Simons, C., Nahkuri, S., Oey, H., Korbie, D., Mercer, T., Holst, J., Ritchie, W., Wong, J., Rasko, J., Rokhsar, D., Degnan, B., Mattick, J. (2010), Nuclear-localized tiny RNAs are associated with transcription initiation and splice sites in metazoans. Nature structural & molecular biology. 17(8), 1030-4. [Abstract]
  • Flamant, S., Ritchie, W., Guilhot, J., Holst, J., Bonnet, M., Chomel, J., Guilhot, F., Turhan, A., Rasko, J. (2010), Micro-RNA response to imatinib mesylate in patients with chronic myeloid leukemia. Haematologica. 95(8), 1325-33. [Abstract]
  • Vanslambrouck, J., Bröer, A., Thavyogarajah, T., Holst, J., Bailey, C., Bröer, S., Rasko, J. (2010), Renal imino acid and glycine transport system ontogeny and involvement in developmental iminoglycinuria. The Biochemical journal. 428(3), 397-407. [Abstract]
  • Wang, H., Holst, J., Woo, S., Guy, C., Bettini, M., Wang, Y., Shafer, A., Naramura, M., Mingueneau, M., Dragone, L., Hayes, S., Malissen, B., Band, H., Vignali, D. (2010), Tonic ubiquitylation controls T-cell receptor:CD3 complex expression during T-cell development. The EMBO Journal. 29(7), 1285-1298. [Abstract]
  • Tiffen, J., Bailey, C., Ng, C., Rasko, J., Holst, J. (2010), Luciferase expression and bioluminescence does not affect tumor cell growth in vitro or in vivo. Molecular Cancer. 9, 299. [Abstract]

2008

   
  • Holst, J., Wang, H., Eder, K., Workman, C., Boyd, K., Baquet, Z., Singh, H., Forbes, K., Chruscinski, A., Smeyne, R., van Oers, N., Utz, P., Vignali, D. (2008), Scalable signaling mediated by T cell antigen receptor-CD3 ITAMs ensures effective negative selection and prevents autoimmunity. Nature immunology. 9(6), 658-666. [Abstract]