Dr Linda Bendall

Principal Research Fellow
Medicine, Westmead Clinical School
Westmead Millennium Institute for Medical Research

C24 - Westmead Hospital
The University of Sydney
NSW 2006 Australia

T: +61 2 9845 9069
F: +61 2 9845 9102
E:

Research interests

The Leukemia Cell Biology Group is focused on the impact of non-hematopoietic cells in the bone marrow on the behaviour of normal blood forming and leukaemia cells. For more detail go to http://www.wmi.usyd.edu.au/ourpeople/profiles/bendall_linda.htm

Keywords

Haematology; Haematological malignancy; Stem cells; Cell biology; Cancer

Publications

2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008

2014

   
  • Wallington-Beddoe, C., Powell, J., Tong, D., Pitson, S., Bradstock, K., Bendall, L. (2014), Sphingosine Kinase 2 Promotes Acute Lymphoblastic Leukemia by Enhancing MYC Expression. Cancer Research. 74(10), 2803-2815. [Abstract]
  • Bendall, L., Green, D. (2014), Autopsy of a cell. Leukemia. , 1341-1343. [Abstract]

2013

   
  • Welschinger, R., Liedtke, F., Basnett, J., Dela Pena, A., Juarez, J., Bradstock, K., Bendall, L. (2013), Plerixafor (AMD3100) induces prolonged mobilization of acute lymphoblastic leukemia cells and increases the proportion of cycling cells in the blood in mice. Experimental Hematology. 41(3), 293-302.e1. [Abstract]
  • Saunders, P., Weiss, J., Welschinger, R., Baraz, R., Bradstock, K., Bendall, L. (2013), RAD001 (everolimus) induces dose-dependent changes to cell cycle regulation and modifies the cell cycle response to vincristine. Oncogene. 32(40), 4789-4797. [Abstract]
  • Wallington-Beddoe, C., Bradstock, K., Bendall, L. (2013), Oncogenic properties of sphingosine kinases in haematological malignancies. British Journal of Haematology. 161(5), 623-638. [Abstract]
  • Bendall, L., Basnett, J. (2013), Role of sphingosine 1-phosphate in trafficking and mobilization of hematopoietic stem cells. Current Opinion in Hematology. 20(4), 281-288. [Abstract]
  • Winkler, I., Bendall, L., Forristal, C., Helwani, F., Nowlan, B., Barbier, V., Shen, Y., Cisterne, A., Sedger, L., Levesque, J. (2013), B-lymphopoiesis is stopped by mobilizing doses of G-CSF and is rescued by overexpression of the anti-apoptotic protein Bcl2. Haematologica. 98(3), 325-333. [Abstract]

2012

   
  • Winkler, I., Pettit, A., Raggatt, L., Jacobsen, R., Forristal, C., Barbier, V., Nowlan, B., Cisterne, A., Bendall, L., Sims, N., Lévesque, J. (2012), Hematopoietic stem cell mobilizing agents G-CSF, cyclophosphamide or AMD3100 have distinct mechanisms of action on bone marrow HSC niches and bone formation. Leukemia. 26(7), 1594-1601. [Abstract]
  • Khan, N., Cisterne, A., Baraz, R., Bradstock, K., Bendall, L. (2012), Para-NO-Aspirin inhibits NF-κB and induces apoptosis in B-cell progenitor acute lymphoblastic leukemia. Experimental hematology. 40(3), 207-215.e1. [Abstract]
  • Juarez, J., Harun, N., Thien, M., Welschinger, R., Baraz, R., Dela Pena, A., Pitson, S., Rettig, M., Dipersio, J., Bradstock, K., Bendall, L. (2012), Sphingosine-1-phosphate facilitates trafficking of hematopoietic stem cells and their mobilization by CXCR4 antagonists in mice. Blood. 119(3), 707-716. [Abstract]
  • Harun, N., Bradstock, K., Bendall, L. (2012), Combination Strategies for Stem Cell Mobilization Targeting CXCR4 and S1P Receptors. In: Novel Developments in Stem Cell Mobilization. (pp.37-54).United States: Springer Science +Business Media.
  • Wallington-Beddoe, C., Don, A., Hewson, J., Qiao, Q., Papa, R., Lock, R., Bradstock, K., Bendall, L. (2012), Disparate In Vivo Efficacy of FTY720 in Xenograft Models of Philadelphia Positive and Negative B-lineage Acute Lymphoblastic Leukemia. PloS One. 7(5), e36429. [Abstract]

2011

   
  • Bendall, L. (2011), It's all in the timing. Blood. 118(23), 5983-5984. [Abstract]
  • To, L., Levesque, J., Herbert, K., Winkler, I., Bendall, L., Hiwase, D., Antonenas, V., Rice, A., Gottlieb, D., Mills, A., Rasko, J., Larsen, S., Beligaswatte, A., Nilsson, S., Cooney, J., Cambareri, A., Lewis, I. (2011), Mobilisation strategies for normal and malignant cells. Pathology. 43(6), 547-565. [Abstract]
  • Wallington-Beddoe, C., Hewson, J., Bradstock, K., Bendall, L. (2011), FTY720 produces caspase-independent cell death of acute lymphoblastic leukemia cells. Autophagy. 7(7), 707-715. [Abstract]
  • Wei, J., Yee, C., Ramanathan, P., Bendall, L., Williamson, P. (2011), Variation in immunophenotype of lactating mice. Journal of reproductive immunology. 89(2), 178-84. [Abstract]
  • Saunders, P., Cisterne, A., Weiss, J., Bradstock, K., Bendall, L. (2011), The mammalian target of rapamycin inhibitor RAD001 (everolimus) synergizes with chemotherapeutic agents, ionizing radiation and proteasome inhibitors in pre-B acute lymphocytic leukemia. Haematologica. 96(1), 69-77. [Abstract]

2010

   
  • Bendall, L. (2010), New and Emerging Drug Targets for the Treatment of Hematological Malignancies. Current drug targets. 11, 767-8. [Abstract]
  • Gaundar, S., Bendall, L. (2010), The Potential and Limitations of p38MAPK as a Drug Target for the Treatment of Hematological Malignancies. Current drug targets. 11(7), 823-33. [Abstract]
  • Sedger, L., Katewa, A., Pettersen, A., Osvath, S., Farrell, G., Stewart, G., Bendall, L., Alexander, S. (2010), Extreme lymphoproliferative disease and fatal autoimmune thrombocytopenia in FasL- and TRAIL-double deficient mice. Blood. 115(16), 3258-68. [Abstract]

2009

   
  • Gaundar, S., Bradstock, K., Bendall, L. (2009), p38MAPK inhibitors attenuate cytokine production by bone marrow stromal cells and reduce stroma-mediated proliferation of acute lymphoblastic leukemia cells. Cell Cycle. 8(18), 2975-2983. [Abstract]
  • Crazzolara, R., Bradstock, K., Bendall, L. (2009), RAD001 (Everolimus) induces autophagy in acute lymphoblastic leukemia. Autophagy. 5(5), 727-728. [Abstract]
  • Juarez, J., Thien, M., Dela Pena, A., Baraz, R., Bradstock, K., Bendall, L. (2009), CXCR4 mediates the homing of B cell progenitor acute lymphoblastic leukaemia cells to the bone marrow via activation of p38MAPK. British Journal of Haematology. 145(4), 491-499. [Abstract]
  • Crazzolara, R., Cisterne, A., Thien, M., Hewson, J., Baraz, R., Bradstock, K., Bendall, L. (2009), Potentiating effects of RAD001 (Everolimus) on vincristine therapy in childhood acute lymphoblastic leukemia. Blood. 113(14), 3297-3306. [Abstract]
  • Crazzolara, R., Bendall, L. (2009), Emerging treatments in acute lymphoblastic leukemia. Current Cancer Drug Targets. 9(1), 19-31. [Abstract]
  • Johnson, M., Sharma, M., Jamieson, C., Henderson, J., Mok, M., Bendall, L., Henderson, B. (2009), Regulation of beta-catenin trafficking to the membrane in living cells. Cellular signalling. 21(0), 339-48. [Abstract]

2008

   
  • Khan, N., Cisterne, A., Devidas, M., Shuster, J., Hunger, S., Shaw, P., Bradstock, K., Bendall, L. (2008), Expression of CD44, but not CD44v6, predicts relapse in children with B cell progenitor acute lymphoblastic leukemia lacking adverse or favorable genetics. Leukemia & Lymphoma. 49(4), 710-718. [Abstract]