Dr Loretta Lau

Senior Lecturer
Paediatrics & Child Health, Children's Hospital, Westmead

C29 - Children's Hospital Westmead
The University of Sydney
NSW 2006 Australia

T: +61 2 9845-3115
F: +61 2 9845-1317

W: Related website
Curriculum vitae

Biographical details

Loretta Lau is the leader of the Neuroblastoma Research Group at the Children's Cancer Research Unit, Kids Research Institute, The Children's Hospital at Westmead. She is also a Senior Lecturer of the Discipline of Paediatrics and Child Health, Sydney Medical School, University of Sydney. She was the Clinical Research Fellow of the Cancer Institute of NSW (2008 - 2010) and is currently a NHMRC Early Career Research Fellow (2011 - 2014. She has received project grants from Cure Cancer Australia Foundation, Pablove Foundation (USA), and clive and Ramaciotti Foundation. [More...]

Research interests

Dr Loretta Lau is a clinician-scientist and paediatric oncologist. Her major research interest is neuroblastoma, a common childhhod cancer. Her laboratory research group located at The Children's Hospital at Westmead focuses on telomere biology and telomnere length maintenance in neuroblastoma.

Current national competitive grants*


Telomere Maintenance in Neuroblastoma
Lau L
NHMRC Training Fellowship ($350,032 over 4 years)

* Grants administered through the University of Sydney


2014 | 2013 | 2012 | 2008


  • Lee, M., Hills, M., Conomos, D., Stutz, M., Dagg, R., Lau, L., Reddel, R., Pickett, H. (2014), Telomere extension by telomerase and ALT generates variant repeats by mechanistically distinct processes. Nucleic Acids Research. 42(3), 1733-1746. [Abstract]
  • Farooqi, A., Dagg, R., Choi, L., Shay, J., Reynolds, C., Lau, L. (2014), Alternative lengthening of telomeres in neuroblastoma cell lines is associated with a lack of MYCN genomic amplification and with p53 pathway aberrations. Journal of Neuro-Oncology. 119(1), 17-26. [Abstract]


  • Lau, L., Dagg, R., Henson, J., Au, A., Royds, J., Reddel, R. (2013), Detection of alternative lengthening of telomeres by telomere quantitative PCR. Nucleic Acids Research. 41(2), e34. [Abstract]


  • Bower, K., Napier, C., Cole, S., Dagg, R., Lau, L., Duncan, E., Moy, E., Reddel, R. (2012), Loss of Wild-Type ATRX Expression in Somatic Cell Hybrids Segregates with Activation of Alternative Lengthening of Telomeres. PloS One. 7(11), e50062. [Abstract]


  • Lau, L., Stuurman, K., Weitzman, S. (2008), Skeletal Langerhans cell histiocytosis in children: permanent consequences and health-related quality of life in long-term survivors. Pediatric blood & cancer. 50(3), 607-12. [Abstract]
  • Lau, L., Nugent, J., Zhao, X., Irwin, M. (2008), HDM2 antagonist Nutlin-3 disrupts p73-HDM2 binding and enhances p73 function. Oncogene. 27(7), 997-1003. [Abstract]