Associate Professor Tracy Bryan

Unit Head, Cell Biology Research Unit
Medicine, Children's Medical Research Institute

T: +61 2 9687 2800
F: +61 2 9687 2120
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W: Related website

Research interests

Dr Bryan discovered a new mechanism for cell immortalization called ALT and has since established her own laboratory to continue studies into the role of telomeres in human tumours.

PhD and Masters' project opportunities

Biochemistry and cell biology of the cancer-associated enzyme telomerase   +

+ indicates the opportunity is full and unavailable.

Keywords

Telomerase; Ageing; Biochemistry

Publications

2012 | 2011 | 2010 | 2009 | 2008

2012

   
  • Conomos, D., Stutz, M., Hills, M., Neumann, A., Bryan, T., Reddel, R., Pickett, H. (2012), Variant repeats are interspersed throughout the telomeres and recruit nuclear receptors in ALT cells. The Journal of Cell Biology. 199(6), 893-906. [Abstract]
  • Yatsunyk, L., Bryan, T., Johnson, F. (2012), G-ruption: the third international meeting on G-quadruplex and G-assembly. Biochimie. 94(12), 2475-2483. [Abstract]
  • Stern, J., Zyner, K., Pickett, H., Cohen, S., Bryan, T. (2012), Telomerase Recruitment Requires both TCAB1 and Cajal Bodies Independently. Molecular and Cellular Biology. 32(13), 2384-2395. [Abstract]

2011

   
  • Bryan, T., Baumann, P. (2011), G-Quadruplexes: From Guanine Gels to Chemotherapeutics. Molecular biotechnology. 49(2), 198-208. [Abstract]
  • Jurczyluk, J., Nouwens, A., Holien, J., Adams, T., Lovrecz, G., Parker, M., Cohen, S., Bryan, T. (2011), Direct involvement of the TEN domain at the active site of human telomerase. Nucleic acids research. 39, 1774-88. [Abstract]

2010

   
  • Bryan, T., Baumann, P. (2010), G-quadruplexes: from guanine gels to chemotherapeutics. Methods in Molecular Biology. 608, 1-16. [Abstract]

2009

   
  • Bryan, T. (2009), Telomeres and the End Replication Problem. In: Molecular Themes in DNA Replication. (pp.217-268).Colchester, UK: RSC Publishing.

2008

   
  • Cao, Y., Bryan, T., Reddel, R. (2008), Increased copy number of the TERT and TERC telomerase subunit genes in cancer cells. Cancer Science. 99(6), 1092-1099. [Abstract]
  • Cao, Y., Huschtscha, L., Nouwens, A., Pickett, H., Neumann, A., Chang, A., Toouli, C., Bryan, T., Reddel, R. (2008), Amplification of telomerase reverse transcriptase gene in human mammary epithelial cells with limiting telomerase RNA expression levels. Cancer research. 68(9), 3115-3123. [Abstract]
  • Finger, S., Bryan, T. (2008), Multiple DNA-binding sites in Tetrahymena telomerase. Nucleic Acids Research. 36(4), 1260-1272. [Abstract]
  • Stern, J., Bryan, T. (2008), Telomerase recruitment to telomeres. Cytogenetic and Genome Research. 122(3-4), 243-254. [Abstract]