Recent Cancer Institute NSW grant outcomes

2014

Research Equipment Grants (REG)

A/Professor Anthony Gill
The University of Sydney, Sydney VITAL
Nanostring nCounter system for gene expression analysis in fresh and formalin fixed paraffin embedded tissue
$500,000

Professor Christine Clarke
Westmead Millennium Institute for Medical Research, Sydney West Translational Cancer Research Centre
Semi-automatic Tissue Microarrayer with digital image integration for enhancement of cancer research within the Sydney West Hub
$124,640

Early Career Fellowships

Dr Alexander Menzies
Identifying predictive biomarkers of current systemic therapies and the discovery of new targets and future treatments to improve survival in metastatic melanoma
$360,000

Dr Michael Marinovich
Evidence translation in breast cancer surgical planning
$324,000

Dr Wing Hin Lee
Inhalable paclitaxel loaded-iron oxide nanoparticle for lung cancer therapy
$592,183

2013

Translational Cancer Research Centres (TCRC)

Associate Professor Alexander Engel
Sydney Vital (formerly Northern Translational Cancer Research Centre (NTCRC)
$6,344,518

Early Career Fellowships

Dr Megan Passey
Reducing tobacco harm among groups with high smoking prevalence
$597,824

Dr Justin Wong
Linking mutations and epigenetic silencing of splicing factors to aberrant splicing in acute myeloid leukaemia
$600,000

Dr John Kipritidis
On-line ventilation imaging to reduce toxicity in lung cancer radiotherapy
$552,883

Dr Sarah Hayes
Identification of predictive biomarkers of treatment response in Non-Small Cell Lung Cancer patients
$599,347

Dr Kimberley Kaufman
Mechanisms of tumour recurrence and chemotherapy escape in glioblastoma multiforme
$535,000

Dr Maté Biro
Mechanobiology of cellular protrusions and the actomyosin cortex in invasive tumour cell migration
$600,000

Dr Kimberley Beaumont
Rab27a as a novel therapeutic target: Investigating the role of Rab27a in melanoma growth and invasion
$568,974

Research Equipment Grants (REG)

Prof Des Richardson
The University of Sydney, Sydney Catalyst
BioMark HD High-throughput Real Time & Digital PCR System for the Open Access, Multi-Disciplinary Sydney Cancer Research Core Facility
$326,895

A/Prof Andrew Katsifis
Sydney Local Health District, Sydney Catalyst
Preparation of PET Radiopharmaceuticals for Imaging Cancer
$325,000

Prof Patrick Brennan
The University of Sydney, Sydney Catalyst
A mobile imaging platform to further transform breast cancer imaging research in NSW initiated by BREAST
$417,524

Prof Phillip Robinson
Children's Medical Research Institute, Kids Cancer Alliance
Multi-centre screening and development platform for pre-clinical drugs for glioblastoma
$426,467

Prof Barbara Fazekas de St Groth
The University of Sydney, Sydney Catalyst
CyTOF mass cytometry platform
$500,000

A/Prof Jennifer Byrne
The University of Sydney, Kids Cancer Alliance
Automated in situ analysis capacity for translational cancer research
$160,000

2012

Research Infrastructure Grants (RIG)

Prof Robert Baxter
University of Sydney, Northern Translational Cancer Research Unit
MALDI MS Imaging for Cancer Biomarker Discovery in the Northern Translational Cancer Research Unit
$299,334

Prof Graham Mann
University of Sydney, Sydney West Translational Cancer Research Centre
Continuing Infrastructure Support for a flow cytometry specialist to manage and operate the expanded Westmead Research Hub Flow Cytometry Centre
$300,000

Prof Des Richardson
University of Sydney, Sydney Catalyst
Advanced Technical Support for the Open Access, Multi-Disciplinary Sydney Cancer Research Core Facility.
Sydney Catalyst$236,153

Prof Christine Clarke[
University of Sydney, Sydney West Translational Cancer Research Centre
Data collection and management for the Australian Breast Cancer Tissue Bank
$300,000

A/Prof Anna de Fazio
University of Sydney, Sydney West Translational Cancer Research Centre
Enhancement of the Gynaecological Oncology Biobank at Westmead and creation of a Sydney West Translational Cancer Research Centre (SW-TCRC) Bio-specimens Hub
$281,161

A/Prof Anthony Gill
University of Sydney, Northern Translational Cancer Research Unit
The creation of a readily accessible and clinically annotated tissue bank of paraffin c blocks containing tumour to mirror and expand frozen tissue collected by the Kolling Tumour Banks
$276,971

Prof Roger Reddel
Children's Medical Research Institute, Kids cancer Alliance
CellBank Australia: Rapid, easy access to novel and essential cancer cell lines and cell line authentication services to enable internationally competitive cancer research.
$300,000

Early Career Fellowships

Dr Zaklina Kovacevic
University of Sydney
Targeting the metastasis suppressor NDRG1 for the treatment of pancreatic cancer
$455,394

Dr Katie Dixon
University of Sydney
Novel vitamin D-like compounds to reduce DNA and other molecular damage after UV radiation
$600,000

Dr Emily Colvin
University of Sydney
Characterising the tumour microenvironment of epithelial ovarian cancer
$599,215

Career Development Fellowships

Dr Hilda Pickett
Children's Medical Research Institute
Molecular mechanisms of telomere length control
$599,110

Dr William Ritchie
University of Sydney
Small non-coding RNAs control alternative splicing in Chronic Myeloid Leukaemia
$600,000

A/Prof Sallie-Anne Pearson
University of Sydney
Post-market surveillance of cancer medicines: Generating evidence for clinical and policy practice using linked health administrative data
$150,000

Dr Linda Bendall
University of Sydney
Microenvironmental Impact in the Treatment of Acute Lymphoblastic Leukaemia
$150,000

Cooperative Clinical Trial Grants

Dr Alison Brand
University of Sydney
Development and operational support for ANZGOG through the NHMRC Clinical Trials Centre: A NSW lead initiative.
300,000.00

Prof Phyllis Butow
University of Sydney
PoCoG infrastructure to support operational activity and facility management to further psychosocial and supportive care clinical trials
299,787.00

Dr Peter Grimison
University of Sydney
Cancer Institute NSW Cooperative Clinical Trial Grant for ANZUP (2013- 2015)
300,000.00

A/Prof Nick Pavlakis
University of Sydney
Development and operational support for the Australasian Lung cancer Trials Group (ALTG) through the NHMRC Clinical Trial Centre: A NSW-led initiative.
300,000.00

Dr Elizabeth Hovey
University of Sydney
COGNO infrastructure funding for support, development and conduct of clinical trials and translational research.
300,000.00

Prof David Goldstein
University of Sydney
Improving patient outcomes for patients with Gastrointestinal (GI) cancer through clinical trials research: An application on behalf of the Australasian Gastro-Intestinal Trials Group (AGITG).
299,976.00

Innovation Grants

Defining a role for GPs and patients in multidisciplinary team decisions on cancer care
University of Sydney and Sydney LHD
$50,000

2011

Translational Cancer Research Centres (TCRCs)

Prof John Simes
University of Sydney
Sydney Catalyst: The Translational Cancer Research Centre of Central Sydney and Regional NSW
$6,350,000

A/Prof Paul Harnett
University of Sydney
Sydney-West Translational Cancer Research Centre
$6,500,000

Translational Cancer Research Units (TCRUs)

Prof Stephen Clarke
University of Sydney
Northern Translational Cancer Research Unit
$1,792,844

Research Infrastructure Grants

Prof Christine Clarke
University of Sydney
High Speed Cell Sorter for Flow Cytometry Core Facility
$550,000

Prof Des Richardson
University of Sydney
Seahorse Extracellular Flux (XF) Analyzer for the Multi-Disciplinary Sydney Cancer Research Core Facility
$315,000

Prof Gary Halliday
University of Sydney
A small animal bioimaging facility for monitoring cancer cells and molecules in vivo
$290,136

Career Development Fellowships

Prof Wolfgang Weninger
University of Sydney
Real time visualisation of tumor associated-antigen specific T cell behaviour in vivo
$600,000

Future Research Leader Fellowships

Dr Anthony Cesare
Children's Medical Research Institute
Targeting TRF2 function to prevent cancer cell growth.
$1,218,795

Translational Program Grants

Prof Derek Hart
University of Sydney
Enabling Diagnostic and Therapeutic Antibodies for Haematological and other Malignancies
$3,466,923

Prof Nico van Zandwijk
Asbestos Diseases Research Institute
Translating Malignant Mesothelioma research into better outcomes for patients and their families
$3,500.00

Cancer Clinical Trials Staff Grants

Prof Michael Boyer
Sydney Local Health District Cancer Trials Network
Allocated Full-time Equivalent (FTE): 6

A/Prof Paul Harnett
The Clinical Trials Network of the Sydney-West Translational Cancer Research Centre: a joint initiation of the Western Sydney and Nepean Blue Mountains Local Health Districts
Allocated Full-time Equivalent (FTE): 5

Dr Nick Pavakis
Northern Sydney Local Health District
Allocated Full-time Equivalent (FTE): 2

Prof John Thompson
Melanoma Institute Australia (MIA) Clinical Trials Program
Allocated Full-time Equivalent (FTE): 1

2010

Epidemiology Linkage Grants

Young J
University of Sydney
Development and evaluation of composite clinical indicators of hospital performance for comparative assessment of the quality of surgical care for colorectal cancer
$322,952

Research Innovation Grants

Catchpoole D
University of Sydney
Implementing personalized medicine using global genomic similarity
$50,000

Butow P
University of Sydney
Assessing unmet needs in women with gynaecological cancers; The first step
$48,679

Richardson D
University of Sydney
The Effect of Anthracyclines on the Iron Metabolism of Leukaemia Cells

Zhang D
University of Sydney
Examination of the tumour suppressor function of endoplasmic reticulum protein 29 (ERp29) in lung cancer and its therapeutic application
$50,000

van Zandwijk N
Asbestos Diseases Research Institute
Identifying new plasma markers in mesothelioma
$50,000

Shaw J
University of Sydney
Development of communication skills training for nurses delivering telephone-based supportive care interventions for people with cancer or their families
$48,431

Early Career Development Fellowships

Cust A
University of Sydney
Epidemiological studies of melanoma etiology and prevention
$570,954

Jansson P
University of Sydney
A Novel Targeting Strategy for the Design of New Chemotherapeutics that Overcome Drug Resistance in Lung Cancer: "High-Jacking" the Drug Efflux Pump, P-gp
$599,892

Lane D
University of Sydney
Novel chemotherapeutic approaches for leukaemia: investigating the anti-cancer activity of ascorbate in relation to leukaemic iron metabolism
$600,000

Career Development Fellowships

Rizos H
University of Sydney
Manipulating oncogenic-signalling pathways in the genesis and treatment of melanoma
$300,000

Hart D
University of Sydney
The Translation of Dendritic Cell Biology into New Cancer Therapies
$596,685

Marsh D
University of Sydney
Understanding endocrine tumorigenesis - opportunities for new diagnostics and therapies
$300,000

Long G
University of Sydney
Determining mechanisms of resistance and heterogeneity of response to novel targeted drugs in metastatic melanoma to improve survival and prevent metastatic disease
$599,895

Charles K
University of Sydney
Inflammatory biomarkers of chemotherapy response in colorectal cancer
$574,509

Clinical Training Fellowships

King T
University of Sydney
A clinical practice initiative to improve the management of adverse effects of steroid therapy associated with the treatment of multiple myeloma
$117,678

Clinical Education Scholarship

Philp S
University of Sydney
Application to apply for funding to undertake a Master of Nursing (Nurse Practitioner) at The University of Sydney
$14,880

Clinical Research Fellowships

Scolyer RA
Sydney South West Area Health Service
Identification and validation of biomarkers of prognosis and treatment response in melanoma to effect change in clinical care and patient outcome
$749,202

Research Scholar Awards

Gao B
University of Sydney
Genetic Basis of Chemotherapy Response in Epithelial Ovarian Cancer
$33,334

Guy T
Centenary Institute of Cancer Medicine and Cell Biology
Strategies to enhance CD4 T cell-mediated anti-tumour immunity
$60,416

Hancock D
Centenary Institute of Cancer Medicine and Cell Biology
Targeting dendritic cells for cancer immunotherapy
$31,250

Kao S
University of Sydney
The Role of Excision Repair Cross Complementation Group 1 and Thymidylate Synthase Expression in Malignant Pleural Mesothelioma
$28,013

Tom N
University of Sydney
Oxytocin Signalling and Inhibition of Hormone Refractory Prostate Cancer
$50,000

Wallington-Beddoe C
University of Sydney
New Therapeutic Strategies for Acute Lymphoblastic Leukaemia: Combining PP2A activation with mTOR inhibition
$58,334

Zhong J
The Children`s Hospital at Westmead
The Role of NEDD9 in Glioblastoma Infiltration.
$33,334

Zhou J
University of Sydney
Discovery of novel protein biomarkers in colorectal cancer (CRC) with potential application for prognosis or therapeutic targeting
$45,833

Zyner K
Children’s Medical Research Institute
Characterisation and targeting of four-stranded structures at cancer cell telomeres
$47,832

Research Equipment Grants

Christopherson R
University of Sydney
A mass spectrometer for multiple reaction monitoring to validate cancer biomarkers
$492,177

Clarke C
University of Sydney
Facilities for cryogenic storage and transport of tissue bank materials
$105,501

Kuncic Z
University of Sydney
The NSW Advanced Computing Facility for Cancer Research
$165,000

Marsh D
University of Sydney
In-Vivo Multispectral Imaging FX System: small animal imaging for multi-modal molecular signal localisation in live animals
$250,000

Richardson D
University of Sydney (USYD)
GenomeLab GeXP Genetic Analysis System for the Multi-Disciplinary Sydney Cancer Gene Expression Facility
$97,438

Sitas F
Cancer Council NSW
Freezers and laboratory information system for Cancer Council NSW Biobank
$247,000

van Zandwijk N
Bernie Banton Asbestos Research Centre, Concord
Malignant Mesothelioma Biobank
$89,899

Vial P
Sydney South West Area Health Service (SSWAHS)
Making radiotherapy safer and more accurate: Developing detector technology for the next generation in treatment verification systems
$198,000

Weninger W
University of Sydney
High speed 3D live cell imaging of cancer genesis, growth, metastasis and death
$328,425

O'Neill G
Childrens Hospital at Westmead
Westmead Correlative Light and Electron Microscopy (CLEM) Suite
$290,000

NSW Registrar Advanced Trainee Grants

Lee SC
Sydney South West Area Health Service (SSWAHS)
Investigation of biomarkers for the diagnosis and prognosis of common cancers in the community such as breast, colorectal, prostate and head and neck cancers
$227,921

Clinical Conference Grants

Stalgis-Bilinski K
Sydney West Area Health Service (SWAHS)
Attendance at the Cancer and Obesity Conference, Valencia, Spain, 12-13 September 2010
$4,475