Recent National Health & Medical Research Council (NHMRC) Project Grant outcomes

2011

Canfell K, Clements M, Nickson C, Brotherton J, Castle P, Schiffman M, Lord S, Shi JF
Evaluation of Primary HPV Testing for Cervical Screening in Australia
$677,522.20

Haass N, Weninger W
Real-time Imaging of cell cycle progression in melanoma
$466,299

Matthews J, Mackay J, Guss J
LMO2-containing complexes in leukemia and blood cell development
$775,914

Marsh D, Baxter R
Pyk2: a central mediator of gonadotropin action in ovarian cancer
$322,524

George J, Hebbard L
Role of adiponectin in hepatic carcinogenesis
$361,082.50

Simanainen U, Handelsman D
Intraprostatic androgen signalling as a target in prostate cancer
$359,208

Bebawy M, Grau G, Combes V
Microparticles and SelectiveTrait Dominance in Multidrug Resistant Cancers
$396,273

Rizos H
Dissecting PTEN-regulated pathways in the genesis of melanoma
$292,524

Rizos Helen, Kefford R, Long G, Zhang XD
Manipulating the B-RAF/MEK pathway in the genesis and treatment of melanoma
$543,390

Halliday G, Lyons JG
Susceptibility of the basal layer of human epidermis to UVA oxidative damage due to pheomelanin and suboptimal DNA repair
$540,048

Nicholas H, Crossley M
Identifying regulators of the DNA damage response and tumourigenesis using C. Elegans
$496,706

Reddel R, Pickett H
Telomere structural abnormalities in cells using alternative lengthening of telomeres
$504,615

Stevenson A, Solomon M, Hewett P, Lumley J, Fleshman J, Clouston A, Hague W
A La CaRT: Australasian phase III randomised trial comparing laparoscopic-assisted versus open resection for rectal cancer
$ 932,568.20

Weninger W
Dynamics and mechanisms of neutrophil migration during tissue inflammation
$511,299

Clarke C, Graham J
Progesterone regulation of epithelial expansion in the normal human breast
$538,549.60

Mackay J, Blobel G
Structural and functional analysis of a cancer-linked coregulator complex
$536,706

Jolly C
Regulation of the quality of DNA repair by timing in the cell Cycle
$452,957

Fazekas De St Groth B, Shklovskaya Elena
Strategies to enhance CD4 T cell-mediated anti-tumour immunity
$511,299

2010

O'Neill G
The cell biology of glioblastoma infiltration
$508,225

Baxter R; Moore L; Marsh D; Boyle F; McCarthy N
Protein discovery for breast cancer diagnosis
$397,125

George J; Hebbard L
The role of the adiponectin receptors in liver fibrosis
$379,125

Young J; Butow P; Soloman M; Davidson P; Martin D; Harrison J
Improving psychosocial outcomes for cancer carers: a randomised control trial
$515,600

Alexander I; McCormack M; Alexander S; Thrasher A; Ginn S
Gene therapy, stress haematopoiesis and the risk of malignancy
$595,500

King M; Viney R; Pallant J; Janda M; Grimison P
Development and valuation of cancer specific multi-attribute health states for use in economic evaluation
$679,750

Richardson D; Sury Rahmanto Y; Kuchel P
Alpha-2-Macroglobulin and the Transport and Uptake of the Hormone, Hepcidin
$514,500

Weninger W; Triccas J
Visualisation of gamma-delta T cell responses in cutaneous inflammation
$550,500

Halliday G; Lyons G; Di Girolamo N; Moloney F; Lee S
Brm and Brg-1 protect from ultraviolet radiation-induced skin and ocular damage
$535,500

Richardson D; Assinder S; Dong Q
Pharmacological Targeting via AKT, PTEN, and TGF-beta Pathway Integration using
Novel Therapeutics

$611,875

Clarke S; Robertson G; Piquette-Miller M; McLachlan, A; Baker M; Katsifis A
Improving the use of chemotherapy by targeting the inflammatory response
$550,500

Crossley M; Bell-Anderson K
Transcriptional control of adipogenesis
$535,125

Liddle C; Downes M
Steroidogenic factor-1, a novel regulator of hepatic stellate cell function
$568,500

Lord S; Houssami N
Incidence and prognosis of metastatic breast cancer: A population-based data linkage study
$95,338

Reddel R; Chang A
Role of STC1 and STC2 in breast carcinogenesis
$402,125

Reddel R
Induction of senescence in cells that use the Alternative Lengthening of Telomeres (ALT) mechanism
$457,125

2009

Grimshaw J
Medicine, Central Clinical School
Determining the role of a novel gene involved in cancer blood supply
$561,500

Vardy J; Dhillon HM; van der Ploeg H; Zalcberg JR; KS Courneya; Meyer RM; Jackson CJ
Medicine, Central Clinical School
Phase III Study of the impact of a physical activity program on disease-free survival for early colon cancer
$2,418,375

Friedlander M; King MT; Gainford MC; Oza A; Fitzgerald PE
Medicine, School of Public Health
Does Palliative Chemotherapy Improve Symptoms in Women with Recurrent Ovarian Cancer?
$502,250

Quinn M; Mileshkin LR; Khaw PYL; Creutzberg CL; Friedlander ML; Gainford MC
Medicine, School of Public Health
Chemoradiation and adjuvant chemotherapy versus radiation alone in high risk and advanced endometrial cancer
$443,125

Chapman S
Medicine, School of Public Health
The use of Web 2.0 internet sites to undermine tobacco advertising bans and to mobilise tobacco control advocates
$351,000

Clarke C; Graham D
Medicine, Western Clinical School
Progesterone signalling in normal and malignant breast relies on chromosomal positioning of progesterone receptor
$546,750

Bryan TM; Cohen SB
Medicine, Children's Medical Research Institute
Structure of human telomerase
$618,500

Richardson D; Rahmanto YS
Medicine, School of Medical Sciences
The Role of Melanoma Tumour Antigen p97 (Melanotransferrin) in Melanoma Tumourenesis
$541,250

Richardson D; Kalinowski DS; Lovejoy DB; Bernhard PV
Medicine, School of Medical Sciences
Pharmacology of Potential Anti-Tumour Agents: Iron Chelators of the BpT Class
$563,500

Henderson B
Medicine, Western Clinical School
Regulation of beta-catenin location and function
$491,500

Butow P; Tattersall MHN; Clayton JM; Young JM; Davidson PM; Epstein RN
Science, Psychology
Improving QOL at the end of life: A randomised controlled trial of a doctor/nurse/patient intervention
$660,800

2008

Bendall, L; Bradstock K
Enhancement of the effects of cytotoxic agents by mTOR inhibitors in acute lymphoblastic leukemia
$642,750

Rizos H; Kefford R
Escape from BRAF-induced human melanocyte senescence in the genesis of melanoma
$577,750

Gill G; Wetzig N; Ung O; Bilous M; Campbell I; Collins J; Hague W; Kirby A
SNAC1:A randomised trial of sentinel node based management versus axillary clearance for women with small breast cancers
$1,272,850

Wetzig N; Campbell I; Gill G; Ung O; Collins J; Bilous M; Hague W; Kirby A
SNAC2: A randomised trial of extending sentinel node based management to women with larger or multifocal breast cancers
$1,185,213

Barratt A; Tattersall M; Askie L; Crossing S; Butow P; Currow D; McGeechan K
Cancer Trials Australia-OnLine: A tool for cancer patients to find open clinical trials and consider trial participation
$505,675

Clarke S; McLachlan A
Inter-ethnic differences in tolerance of anti-cancer drugs
$332,125

Jolly C; Manis J; Alt F
Antibody mutation promotes translocation: a natural cause of cancer
$293,250

Weninger W; Mrass P
Mechanisms of T cell migration and interactions in tumours
$578,250

Liddle C; Downes M
Function of the Vitamin D Receptor in Hepatic Non-Parenchymal Cells
$488,750

O’Neil C
Mechanisms of p53 induced embryopathy after in vitro fertilisation
$464,250

Henderson B
Targeting of the APC tumour suppressor to mitochondria: Implications for APC regulation and cellular function
$443,750

Scott C; Firth S
The role of the M6P/IGF-II receptor in regulating cellular function
$265,500

Clarke C
Progesterone regulation of epithelial cell lineages in the breast
$512,438

O’Neil F; Gunning P
Understanding focal adhesion dynamics in cell migration
$258,250

Mason R; Reeve V; Halliday G
Mechanisms of photoprotection by vitamin D and analogs
$420,563

Matthews J; Guss J; Trewhella J
Transcriptional complexes in haematopoiesis and T-cell Leukemia
$535,500

Suchowerska N; Jackson M; McKenzie D
Rectal invivo radiotherapy dosimetry using a Fibre Optic Array
$416,675

Bendall L; Bradstock K
Antagonists of p38 MAPK as therapeutics for acute lymphoblastic leukemia
$501,000

2007

Armstrong B
Medicine, School of Public Health
Sun exposure, vitamin D and the outcome of prostate cancer
$468,013

Armstrong B
Medicine, School of Public Health
A polypill to prevent genome damage
$395,663

McCaffery K
Medicine, School of Public Health
A randomised controlled trial of a bowel cancer screening decision aid for adults with low education and literacy
$229,500

Baxter R
Medicine, Northern Clinical School
Proteomic screening for apoptotic markers in breast cancer
$511,000

Carter S
Medicine, Central Clinical School
How do lay people understand the risk of developing cancer? A qualitative study using grounded theory procedures.
$271,125

Gill G
Medicine, Central Clinical School
SNAC1: A randomised trial of sentinel node based management versus axillary clearance for women with small breast cancers
$235,613

Halliday G
Medicine, Central Clinical School
Effect of ultraviolet radiation on development of effector and memory T cells to melanoma
$478,500

Vardy J
Medicine, Medical Psychology Unit
Cognitive Function and Fatigue in Cancer Patients After Chemotherapy
$237,525

Butow P
Science, Psychology
Psychosocial predictors of developing breast cancer in women from high risk breast cancer families
$1,020,600

Butow P
Science, Psychology
Psychological morbidity, unmet needs and patterns of care in culturally and linguistically diverse cancer patients in Australia
$401,755

2006

Harnett P
Medicine, Western Clinical School (Westmead Millennium Institute)
Certain death in uncertain time: a qualitative study of the experience of advanced ovarian cancer
$217,500

Clarke C
Medicine, Western Clinical School (Westmead Millennium Institute)
Impact of progesterone receptor submuclear localisation on progesterone action in endocrine target cells
$450,750

Soon L
Science, Electron Microscope Unit
Mechanisms of motility and metastasis in breast cancer
$205,250

Henderson B
Medicine, Western Clinical School (Westmead Millennium Institute)
Regulation of beta-catenin localisation and its role in tumour cell migration
$266,250

Halliday G
Medicine, Central Clinical School
Role of brm in skin tumour progression from benign to malignant
$447,750

Seibel M
Medicine, Central Clinical School (ANZAC Research Institute)
Glucocorticoid effects on bone: the role of the osteoblast
$455,250