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Unit of study_

Molecular Biology and Biochemistry-Genes (BCHM3071)

This unit of study is designed to provide a comprehensive coverage of the activity of genes in living organisms, with a focus on eukaryotic and particularly human systems. The lecture component covers the arrangement and structure of genes, how genes are expressed, promoter activity and enhancer action. This leads into discussions on the biochemical basis of differentiation of eukaryotic cells, the molecular basis of imprinting, epigenetics, and the role of RNA in gene expression. Additionally, the course discusses the effects of damage to the genome and mechanisms of DNA repair. The modern techniques for manipulating and analysing macromolecules such as DNA and proteins and their relevance to medical and biotechnological applications are discussed. Techniques such as the generation of gene knockout and transgenic mice are discussed as well as genomic methods of analysing gene expression patterns. Particular emphasis is placed on how modern molecular biology and biochemical methods have led to our current understanding of the structure and functions of genes within the human genome. The practical course is designed to complement the lecture course and will provide students with experience in a wide range of techniques used in molecular biology laboratories.

Classes
Two 1-hour lectures per week; two 3-hours practicals per fortnight

Assessment
One 2.5-hour exam (theory and theory of prac 70%), in-semester practical work and assignments (30%)

Textbooks
Lewin, B. Genes XI. 11th edition. Jones and Bartlett. 2014.

Additional information
BMedSc degree students: You must have successfully completed BMED2401 and an additional 12cp from BMED240X before enrolling in this unit.

Pre-requisites

[12cp from (BCHM2X71 or BCHM2X72 or BCMB2X01 or BCMB2X02 or MBLG2X71)] OR [BMED2401 and BMED2405 and 6cp from (BCHM2X71 or BCMB2X02 or MBLG2X71)]

Prohibitions

BCHM3971

Details

Semester 1

05 Mar 2018

Department/School: Life and Environmental Sciences Academic Operations
Study Mode: Normal (lecture/lab/tutorial) day
Census Date: 31 Mar 2018
Unit of study level: Senior
Credit points: 6.0
EFTSL: 0.125
Available for study abroad and exchange: Yes
Faculty/department permission required? No
Location
Census dates shows the latest date to cancel out of a unit*
Unit of Study coordinator: Jill Johnston, Dr Hannah Nicholas
HECS Band: 2
Courses that offer this unit

Non-award/non-degree study If you wish to undertake one or more units of study (subjects) for your own interest but not towards a degree, you may enrol in single units as a non-award student. Cross-institutional study If you are from another Australian tertiary institution you may be permitted to undertake cross-institutional study in one or more units of study at the University of Sydney.

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