Proteomics and Functional Genomics (BCHM3092)


This unit of study will focus on the high throughput methods for the analysis of gene structure and function (genomics) and the analysis of proteins (proteomics), which are at the forefront of discovery in the biomedical sciences. The course will concentrate on the hierarchy of gene-protein-structure-function through an examination of modern technologies built on the concepts of genomics versus molecular biology, and proteomics versus biochemistry. Technologies to be examined include DNA sequencing, nucleic acid and protein microarrays, two-dimensional gel electrophoresis of proteins, uses of mass spectrometry for high throughput protein identification, isotope tagging for quantitative proteomics, high-performance liquid chromatography, high-throughput functional assays, affinity chromatography and modern methods for database analysis. Particular emphasis will be placed on how these technologies can provide insight into the molecular basis of changes in cellular function under both physiological and pathological conditions as well as how they can be applied to biotechnology for the discovery of biomarkers, diagnostics, and therapeutics. The practical component is designed to complement the lecture course and will provide students with experience in a wide range of techniques used in proteomics and genomics.

Our courses that offer this unit of study

Further unit of study information


Two 1-hour lectures per week and one 3-hour practical per week.


One 2.5-hour exam (theory and theory of prac 70%), in-semester (practical work and assignments 30%)

Faculty/department permission required?


Unit of study rules


[12 credit points of (MBLG2071, MBLG2971, BCHM2071, BCHM2971, BCHM2072, BCHM2972)] OR [(BMED2401, BMED2405 and 6 additional credit points of BMED240X) and (MBLG2071 or MBLG2971 or BCHM2071 or BCHM2971)]


BCHM3992 or BCHM3098 

Study this unit outside a degree

Non-award/non-degree study

If you wish to undertake one or more units of study (subjects) for your own interest but not towards a degree, you may enrol in single units as a non-award student.

Cross-institutional study

If you are from another Australian tertiary institution you may be permitted to underake cross-institutional study in one or more units of study at the University of Sydney.