Human Molecular Cell Biology (Advanced) (BCHM3972)

UNIT OF STUDY

This unit of study will explore the responses of cells to changes in their environment in both health and disease. The lecture course consists of four integrated modules. The first will provide an overview of the role of signalling mechanisms in the control of human cell biology and then focus on cell surface receptors and the downstream signal transduction events that they initiate. The second will examine how cells detect and respond to pathogenic molecular patterns displayed by infectious agents and injured cells by discussing the roles of relevant cell surface receptors, cytokines and signal transduction pathways. The third and fourth will focus on the life, death and differentiation of human cells in response to intra-cellular and extra-cellular signals by discussing the eukaryotic cell cycle under normal and pathological circumstances and programmed cell death in response to abnormal extra-cellular and intra-cellular signals. In all modules emphasis will be placed on the molecular processes involved in human cell biology, how modern molecular and cell biology methods have led to our current understanding of them and the implications of them for pathologies such as cancer. The practical component is designed to complement the lecture course, providing students with experience in a wide range of techniques used in modern molecular cell biology.
The lecture component of this unit of study is the same as BCHM3072. Qualified students will attend seminars/practical classes in which more sophisticated topics in modern molecular cell biology will be covered.

Our courses that offer this unit of study

Further unit of study information

Classes

Two 1-hour lectures per week and one 6-hour practical per fortnight.

Assessment

One 2.5-hour exam, practical work (100%)

Textbooks

Alberts, B. et al. Molecular Biology of the Cell. 5th edition. Garland Science. 2008.

Faculty/department permission required?

No

Unit of study rules

Prerequisites and assumed knowledge

(MBLG1001/1901) and Distinction in 12 CP of Intermediate BCHM/MBLG units (taken from MBLG2071/2971 or BCHM2071/2971 or BCHM2072/2972). For BMedSc: (18 credit points of BMED including BMED2401 and Distinction in BMED2405 and one of MBLG2071/2971 or BCHM2071/2971) or (Distinction average in BMED2801 and BMED2802 and BMED2804).

Prohibitions

BCHM3072, BCHM3004, BCHM3902, BCHM3904, BCHM3002

Study this unit outside a degree

Non-award/non-degree study

If you wish to undertake one or more units of study (subjects) for your own interest but not towards a degree, you may enrol in single units as a non-award student.

Cross-institutional study

If you are from another Australian tertiary institution you may be permitted to underake cross-institutional study in one or more units of study at the University of Sydney.