Genetics of Brain and Mind Disorders (BMRI5017)
UNIT OF STUDY
This unit of study provides a comprehensive introduction to the research methods involved in identification and characterisation of genetic variants underlying neuropsychiatric disorders. The first part of the unit will focus on the statistical methods to quantify the contribution of genetic factors to disorders in the population. Heredity and epidemiology of neuropsychiatric and neurodevelopmental disorders will be discussed. The course will then discuss concepts of genetic architecture and linkage and students will learn to use bioinformatics tools. Methods used to examine and control gene expression in animal models will also be explored. This is capstone unit of study that will require students to develop over the semester an original piece of scholarship on one of the issues raised by the lectures. Through the course students use bioinformatics tools to study gene regions inherited with a disorder of interest and validate candidate gene. The research report will be carried out in two parts over semester and will require significant research and critique of the relevant literature.
Further unit of study information
2hr seminar week 1, one day workshop week 4, 8 and 12
research report part 1 (30%), research report part 2 (40%), extended response questions (30%)
Strachan, T., Read, A. (2011) Human Molecular Genetics 4th Ed. Garland Science
Faculty/department permission required?
Study this unit outside a degree
If you wish to undertake one or more units of study (subjects) for your own interest but not towards a degree, you may enrol in single units as a non-award student.
If you are from another Australian tertiary institution you may be permitted to underake cross-institutional study in one or more units of study at the University of Sydney.