Biomarker Studies (CLTR5005)


The special skills of translational research will be highlighted in this unit. Candidates will understand the potential uses for biomarkers in clinical practice; how to use study designs relevant for biomarker evaluation and how to incorporate biomarker studies and biospecimen (tissue and blood) collection into clinical research projects. Candidates will learn the difference between prognostic, predictive and surrogate biomarkers and biostatistical considerations in their analysis. The complexities of international regulations regarding patient consent, biospecimen collection and shipment will be highlighted.

Our courses that offer this unit of study

Further unit of study information


discussion groups and problem based learning


2x quizzes (2x10%), 2x assessments (2x40%)


Recommended reading: Altman DG, McShane LM, Sauerbrei W, Taube SE (2012)Reporting Recommendations for Tumor Marker Prognostic Studies (REMARK): Explanation and Elaboration.PLoS Med (5): e1001216. doi:10.1371/journal.pmed.1001216

Faculty/department permission required?


Unit of study rules



Study this unit outside a degree

Non-award/non-degree study

If you wish to undertake one or more units of study (subjects) for your own interest but not towards a degree, you may enrol in single units as a non-award student.

Cross-institutional study

If you are from another Australian tertiary institution you may be permitted to underake cross-institutional study in one or more units of study at the University of Sydney.