Molecular Biology and Genetics (Adv) (MBLG1901)

UNIT OF STUDY

The lectures in this unit of study introduce the "Central Dogma" of molecular biology and genetics, i.e., the molecular basis of life. The course begins with the information macro-molecules in living cells: DNA,RNA and protein, and explores how their structures allow them to fulfill their various biological roles. This is followed by a review of how DNA is organised into genes leading to discussion of replication and gene expression (transcription and translation). The unit concludes with an introduction to the techniques of molecular biology and, in particular, how these techniques have led to an explosion of interest and research in Molecular Biology. The practical component complements the lectures by exposing students to experiments which explore the measurement of enzyme activity, the isolation of DNA and the 'cutting' of DNA using restriction enzymes. However,a key aim of the practicals is to give students higher level generic skills in computing, communication, criticism, data analysis/evaluation and experimental design. The advanced component is designed for students interested in continuing in molecular biology. It consists of 7 advanced lectures (replacing 7 regular lectures) and 3 advanced laboratory sessions (replacing 3 regular practical classes). The advanced lectures will focus on the experiments which led to key discoveries in molecular biology. The advanced practical sessions will give students the opportunity to explore alternative molecular biology experimental techniques. Attendance at MBLG1999 seminars is strongly encouraged.

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Further unit of study information

Classes

Two 1-hour lectures per week; one 1-hour tutorial and one 4-hour practical per fortnight; four 1-hour seminars per semester.

Assessment

One 2.5-hour exam, in-semester skills test and assignments (100%)

Textbooks

Introduction to Molecular Biology MBLG1001 & MBLG1901, 3rd edition compiled by D. Hancock, G. Denyer and B. Lyon, Pearson ISBN 978 1 4860 0039 5

Faculty/department permission required?

No

Unit of study rules

Prerequisites and assumed knowledge

Minimum Band 5 in HSC Chemistry and HSC Biology, or 6 credit points from both Chemistry and Biology., UAI (or ATAR equivalent) of 95 or by invitation

Assumed knowledge: HSC Chemistry and Biology OR 6 credit points of Junior Biology and 6 credit points of Junior Chemistry

Prohibitions

MBLG2871, MBLG2101, BCHM2001, BCHM2901, MBLG2771, AGCH2001, MBLG1001, BCHM2101, MBLG2111, MBLG2901, MBLG2001

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Cross-institutional study

If you are from another Australian tertiary institution you may be permitted to underake cross-institutional study in one or more units of study at the University of Sydney.

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