Molecular Biology and Genomics (MBLG2071)

UNIT OF STUDY

The flow of genetic information determines the characteristics and fate of every cell. In this course, we will explore how genetic information is regulated in eukaryotes, covering key processes such as replication, transcription and translation. We will investigate how these fundamental processes can be studied and manipulated in the laboratory. This course will introduce classical tools of molecular biology such as polymerase chain reaction, as well as more recent advances such as gene expression microarrays and novel sequencing technologies. We will discuss how model organisms, ranging from worms to transgenic mice, have changed our understanding of gene expression. In the practical component of the course, we will explore gene regulation and expression using model system as well as perform plasmid isolation and DNA fingerprinting. This unit of study extends the basic concepts introduced in MBLG1001/1901 and provides a firm foundation for students wishing to continue in molecular biology or apply molecular techniques to other fields.

Our courses that offer this unit of study

Further unit of study information

Classes

Two 1-hour lectures per week and one 4-hour practical per fortnight.

Assessment

One 2.5-hour exam, practical work, laboratory reports (100%)

Textbooks

Watson, J et al. Molecular Biology of the Gene. Pearson 7th edition, 2013.

Faculty/department permission required?

No

Unit of study rules

Prerequisites and assumed knowledge

(MBLG1001 or MBLG1901) and 12 CP of Junior Chemistry

Prohibitions

BCHM2001, MBLG2111, MBLG2871, BCHM2901, AGCH2001, MBLG2901, BCHM2101, MBLG2101, MBLG2971, MBLG2771, MBLG2001

Study this unit outside a degree

Non-award/non-degree study

If you wish to undertake one or more units of study (subjects) for your own interest but not towards a degree, you may enrol in single units as a non-award student.

Cross-institutional study

If you are from another Australian tertiary institution you may be permitted to underake cross-institutional study in one or more units of study at the University of Sydney.