Molecular Biology and Genomics (Adv) (MBLG2971)


The content is based on the standard unit MBLG2071 but certain aspects will be investigated in greater depth and at a more advanced level. The flow of genetic information determines the characteristics and fate of every cell. In this course, we will explore how genetic information is regulated in eukaryotes, covering key processes such as replication, transcription and translation. We will investigate how these fundamental processes can be studied and manipulated in the laboratory. This course will introduce classical tools of molecular biology such as polymerase chain reaction, as well as more recent advances such as gene expression microarrays and novel sequencing technologies. We will discuss how model organisms, ranging from worms to transgenic mice, have changed our understanding of gene expression. In the practical component of the course, we will explore gene regulation and expression using model systems, clone a DNA fragment into a vector and determine its identity by perfomring a plasmid isolation and restriciton enzyme digest, use PCR to determine the geneotypes of transgenic mice as well as perform DNA fingerprinting. This unit of study extends the basic concepts introduced in MBLG1001/1901 and provides a firm foundation for students wishing to continue in molecular biology or apply molecular techniques to other fields.

Our courses that offer this unit of study

Further unit of study information


Two 1-hour lectures per week; one 4-hour practical per fortnight, one 2 hour poster session.


One 2.5-hour exam (theory and theory of practical 70%), in-semester (practical work and assignments 30%)

Faculty/department permission required?


Unit of study rules


12cp from CHEM1XXX and a mark of 75 or above in 6cp from (BIOL1XX7, MBLG1XXX)


MBLG2901 or MBLG2001 or BCHM2001 or AGCH2001 or MBLG2101 or MBLG2871 or MBLG2111 or MBLG2771 or BCHM2101 or MBLG2071 or BCHM2901 

Study this unit outside a degree

Non-award/non-degree study

If you wish to undertake one or more units of study (subjects) for your own interest but not towards a degree, you may enrol in single units as a non-award student.

Cross-institutional study

If you are from another Australian tertiary institution you may be permitted to underake cross-institutional study in one or more units of study at the University of Sydney.