Molecular Biology and Genomics (Adv) (MBLG2971)
UNIT OF STUDY
The content will be based on the standard unit MBLG2071 but certain aspects will be investigated in greater depth and at a more advanced level. The flow of genetic information determines the characteristics and fate of every cell. In this course, we will explore how genetic information is regulated in eukaryotes, covering key processes such as replication, transcription and translation. We will investigate how these fundamental processes can be studied and manipulated in the laboratory. This course will introduce classical tools of molecular biology such as polymerase chain reaction, as well as more recent advances such as gene expression microarrays and novel sequencing technologies. We will discuss how model organisms, ranging from worms to transgenic mice, have changed our understanding of gene expression. In the practical component of the course, we will explore gene regulation and expression using model system as well as perform plasmid isolation and DNA fingerprinting. This unit of study extends the basic concepts introduced in MBLG1001/1901 and provides a firm foundation for students wishing to continue in molecular biology or apply molecular techniques to other fields.
Further unit of study information
Two 1-hour lectures per week; one 4-hour practical per fortnight.
One 2.5-hour exam, practical work, laboratory reports.
Watson, J et al. Molecular Biology of the Gene. Pearson 7th edition, 2013.
Faculty/department permission required?
Unit of study rules
Prerequisites and assumed knowledge
Distinction in either (MBLG1001 or MBLG1901) and 12 credit points of Junior Chemistry
MBLG2071 or MBLG2771 or MBLG2871 or MBLG2001 or MBLG2101 or MBLG2901 or MBLG2111 or AGCH2001 or BCHM2001 or BCHM2101 or BCHM2901
Study this unit outside a degree
If you wish to undertake one or more units of study (subjects) for your own interest but not towards a degree, you may enrol in single units as a non-award student.
If you are from another Australian tertiary institution you may be permitted to underake cross-institutional study in one or more units of study at the University of Sydney.