Drug Design and Development (PCOL3012)

UNIT OF STUDY

This unit of study is designed to introduce students with a basic understanding of pharmacology to the field of medicinal chemistry associated with drug design and development. The course covers the fundamental aspects of drug discovery and development with reference to the essentials of chemistry and illustrates drug development with examples that include neuraminidase inhibitors and ACE inhibitors. The role of computers in drug design is emphasised by classwork and assignments on molecular modelling and structure-activity relationships. The course also extends to a section on the design of diverse pharmacological agents which include compounds for imaging by positron emission tomography (PET), and kinase inhibitors.

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Further unit of study information

Classes

Two 1 hour lectures and one 3 hour tutorial/practical per week.

Assessment

One 2 hour exam, in class quizzes, assignments (100%)

Textbooks

Patrick, Graham L. An Introduction to Medicinal Chemistry. 6th edition. Oxford University Press. 2013.

Faculty/department permission required?

No

Unit of study rules

Prerequisites and assumed knowledge

PCOL2011 and PCOL2012. For BMedSc: 18 credit points of BMED including BMED2401 or (BMED2801 and BMED2802).

Prohibitions

PCOL3901, PCOL3001, PCOL3912

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Non-award/non-degree study

If you wish to undertake one or more units of study (subjects) for your own interest but not towards a degree, you may enrol in single units as a non-award student.

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Cross-institutional study

If you are from another Australian tertiary institution you may be permitted to underake cross-institutional study in one or more units of study at the University of Sydney.

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