Drug Discovery and Design A (PHAR2811)
UNIT OF STUDY
This unit of study aims to provide the background to the study of drugs and the important interactions of drugs and their targets. Learning about the molecular bases of such interactions requires discussions of the fundamental macromolecules of life: DNA, RNA and proteins and processes as replication, transcription and translation. The course therefore also covers the fundamental mechanisms of the regulation of targets, as well as fundamental molecular interactions important for both detection and diagnostic applications for drugs and metabolites. Fuel metabolism and storage is considered, including metabolic adaptation and disorders of metabolism. Students get experience with a variety of practical techniques to assist learning in the course.
Further unit of study information
3 x lectures/wk and tutorials scheduled as required
2.5 hr exam (65%), laboratories and workshops (25%), major quiz (10%)
Patrick, GL. An Introduction to Medicinal Chemistry (5th ed) Oxford University Press, 2013; Nelson, DL. and Cox, MM. Lehninger: Principles of Biochemistry (6th ed), W.H. Freeman, 2013
Faculty/department permission required?
Unit of study rules
Prerequisites and assumed knowledge
(CHEM1611 or CHEM1102 or CHEM1902) and (CHEM1612 or CHEM1101 or CHEM1901) and PHAR1811 and PHAR1812 and (MBLG1991 or BIOL1992 or MBLG1001 or MBLG1901)
Study this unit outside a degree
If you wish to undertake one or more units of study (subjects) for your own interest but not towards a degree, you may enrol in single units as a non-award student.
If you are from another Australian tertiary institution you may be permitted to underake cross-institutional study in one or more units of study at the University of Sydney.