Drug Discovery and Design A (PHAR2811)


This unit of study aims to provide the background to the study of drugs and the important interactions of drugs and their targets. Learning about the molecular bases of such interactions requires consideration of the fundamental processes as replication, transcription and translation involving the macromolecules of life: proteins, DNA and RNA. The course also covers fundamental protein actions and mechanisms of the regulation of such targets, as well as fundamental molecular interactions important for understanding the action of, the detection of, and also diagnostic approaches applied to drugs and metabolites. Fuel metabolism and storage is considered, including metabolic adaptation and disorders of metabolism. Students get experience with a variety of practical techniques to assist learning in the course.

Our courses that offer this unit of study

Further unit of study information


3 x lectures/wk and tutorials scheduled as required


2.5 hr exam (65%), laboratories and workshops (25%), major quiz (10%)


Patrick, GL. An Introduction to Medicinal Chemistry (5th ed) Oxford University Press, 2013; Nelson, DL. and Cox, MM. Lehninger: Principles of Biochemistry (6th ed), W.H. Freeman, 2013

Faculty/department permission required?


Unit of study rules


(CHEM1611 or CHEM1102) and (CHEM1612 or CHEM1101) and PHAR1812 and (MBLG1001 or MBLG1901 or BIOL1007 or BIOL1907 or BIOL1997).

Study this unit outside a degree

Non-award/non-degree study

If you wish to undertake one or more units of study (subjects) for your own interest but not towards a degree, you may enrol in single units as a non-award student.

Cross-institutional study

If you are from another Australian tertiary institution you may be permitted to underake cross-institutional study in one or more units of study at the University of Sydney.