Drug Discovery and Design A (PHAR2811)

UNIT OF STUDY

This unit of study aims to provide the background to the study of drugs and the important interactions of drugs and their targets. Learning about the molecular bases of such interactions requires discussions of the fundamental macromolecules of life: DNA, RNA and proteins and processes as replication, transcription and translation. The course therefore also covers the fundamental mechanisms of the regulation of targets, as well as fundamental molecular interactions important for both detection and diagnostic applications for drugs and metabolites. Fuel metabolism and storage is considered, including metabolic adaptation and disorders of metabolism. Students get experience with a variety of practical techniques to assist learning in the course.

Our courses that offer this unit of study

Further unit of study information

Classes

3 x lectures/wk and tutorials scheduled as required

Assessment

2.5 hr exam (65%), laboratories and workshops (25%), major quiz (10%)

Textbooks

Patrick, GL. An Introduction to Medicinal Chemistry (5th ed) Oxford University Press, 2013; Nelson, DL. and Cox, MM. Lehninger: Principles of Biochemistry (6th ed), W.H. Freeman, 2013

Faculty/department permission required?

Yes

Unit of study rules

Prerequisites and assumed knowledge

(CHEM1611 or CHEM1102), (CHEM1612 or CHEM1101), PHAR1811, PHAR1812, MBLG1001

Study this unit outside a degree

Non-award/non-degree study

If you wish to undertake one or more units of study (subjects) for your own interest but not towards a degree, you may enrol in single units as a non-award student.

Cross-institutional study

If you are from another Australian tertiary institution you may be permitted to underake cross-institutional study in one or more units of study at the University of Sydney.