Pharmaceutical Chemistry 1A (PHAR5513)


This unit will explore the physicochemical properties of drugs and how this determines the interactions of small molecules (drugs) with biological macromolecules (enzymes and receptors). All stages in the process of drug design and development will be investigated, including computational drug design, structure activity studies, synthesis and activity assays. Students will also gain experience in a variety of experimental techniques related to drug design. In addition, students will develop skills including critical thinking, the use of information technology and report writing.

Further unit of study information


2 x lectures/wk, 5 x 2hr tutorials, 4 x 4hr workshops and self-directed learning


Exam (60%), laboratories (20%), and molecular modeling (20%)


Patrick GL. An Introduction to Medicinal Chemistry (5th ed). Oxford University Press, 2013

Faculty/department permission required?


Unit of study rules

Assumed knowledge

3 credit points of Calculus, 3 credit points of Statistics, 6 credit points of Biochemistry, 12 credit points of Chemistry. Students who have not completed up to 12 credit points of pre-requisite subjects are strongly advised to take the corresponding Bridging Course offered in February, July and as a distance course at other times of the year.

Study this unit outside a degree

Non-award/non-degree study

If you wish to undertake one or more units of study (subjects) for your own interest but not towards a degree, you may enrol in single units as a non-award student.

Cross-institutional study

If you are from another Australian tertiary institution you may be permitted to underake cross-institutional study in one or more units of study at the University of Sydney.