Pharmaceutical Chemistry 1B (PHAR5516)

UNIT OF STUDY

This unit of study utilises the knowledge gained in PHAR5513 Pharmaceutical Chemistry 1A to develop students' ability to apply basic scientific and medicinal chemistry concepts in the rationalization of observed biological activities for a series of drug molecules. The unit of study will be presented as a series of discrete topic areas based on therapeutic classes (hormonal, cardiovascular, herbal medicines, central nervous system, chemotherapy, antihistamines, photochemotherapy and sunscreens) and macromolecular targets (enzyme, G-protein coupled receptor, nuclear receptor). Lectures will be supported by self-directed learning and tutorials. Students will also undertake quantitative structure-activity relationship (QSAR) computer-based workshops and herbal medicine practicals as well as prepare a herbal medicine assay and oral presentation. These learning activities will further develop students' skills in critical thinking, the use of information technology and report writing.

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Further unit of study information

Classes

3 x lectures/tutorials per week, 10 hours of self-directed learning

Assessment

2 x 1.5 hr exams (65%); laboratories & workshops (35%)

Textbooks

Foye's Principles of Medicinal Chemistry (6th edn), edited by TL Lemke&DA Williams, Williams & Wilkins, 2008 Medicinal Chemistry (4th edn), Patrick (2009)

Practical work

4hr laboratory practical and 2 x 3hrs herbal workshops

Faculty/department permission required?

No

Unit of study rules

Corequisites

PHAR5513 and PHAR5515

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Cross-institutional study

If you are from another Australian tertiary institution you may be permitted to underake cross-institutional study in one or more units of study at the University of Sydney.

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