Pharmaceutical Chemistry 1B (PHAR5516)


This unit of study utilises the knowledge gained in PHAR5513 Pharmaceutical Chemistry 1A to develop students' ability to apply basic scientific and medicinal chemistry concepts in the rationalization of observed biological activities for a series of drug molecules. The unit of study will be presented as a series of discrete topic areas based on therapeutic classes (hormonal, cardiovascular, herbal medicines, central nervous system, chemotherapy, antihistamines, photochemotherapy and sunscreens) and macromolecular targets (enzyme, G-protein coupled receptor, nuclear receptor). Lectures will be supported by self-directed learning and tutorials. Students will also undertake quantitative structure-activity relationship (QSAR) computer-based workshops and herbal medicine practicals as well as prepare a herbal medicine assay and oral presentation. These learning activities will further develop students' skills in critical thinking, the use of information technology and report writing.

Further unit of study information


3 x lectures/tutorials per week, 10 hours of self-directed learning


2 x 1.5 hr exams (65%); laboratories & workshops (35%)


Foye's Principles of Medicinal Chemistry (6th edn), edited by TL Lemke&DA Williams, Williams & Wilkins, 2008
Medicinal Chemistry (4th edn), Patrick (2009)

Faculty/department permission required?


Unit of study rules

Assumed knowledge

3 credit points of Calculus, 6 credit points of Biochemistry, 12 credit points of Chemistry. Students who have not completed up to 12 credit points of prerequisite subjects are strongly advised to take the corresponding Bridging Course (offered in February, July and as a distance course at other times of the year)


PCOL5001 and PHAR5513 and PHAR5515 and PHAR5517 and PHAR5518

Study this unit outside a degree

Non-award/non-degree study

If you wish to undertake one or more units of study (subjects) for your own interest but not towards a degree, you may enrol in single units as a non-award student.

Cross-institutional study

If you are from another Australian tertiary institution you may be permitted to underake cross-institutional study in one or more units of study at the University of Sydney.