Heart and Circulation: Normal Function (PHSI3007)

UNIT OF STUDY

The aim of this unit of study is to examine in depth the structure and function of the cardiovascular system at the organ system, cellular and molecular levels. There is a particular focus on exercise physiology and the way in which the heart, circulation and skeletal muscles contribute to the limits of sporting achievement. The excitability, contractility and energetics of the heart and blood vessels are studied and the regulation of these organs by local (physical and chemical) factors, hormones and the nervous system are discussed, with emphasis on cellular and molecular mechanisms. At the systemic level, short term (neural) mechanisms controlling the blood pressure and how the system behaves during exercise (including muscle physiology) and other stresses is dealt with. Long term (hormonal) mechanisms regulating blood pressure via the renal control of extracellular fluid volume is also discussed. There is an emphasis in this unit of study on recent advances in cellular and molecular aspects of heart and the blood vessels and the regulation of these organs by local (physical and chemical) factors, hormones and the autonomic nervous system. Lectures will be complemented by practical classes and tutorials that reinforce the theory and emphasise experimental design, data interpretation and presentation.

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Further unit of study information

Classes

Two 1-hour lectures and one 3-hour practical or one 2-hour tutorial per week.

Assessment

One 2-hour exam, 3 practical assignments (100%)

Faculty/department permission required?

No

Unit of study rules

Prerequisites and assumed knowledge

Except for BMedSc students: (PHSI2005 or PHSI2905) and (PHSI2006 or PHSI2906) plus at least 12 credit points of intermediate Science Units of Study. For BMedSc students: 18 credit points of BMED intermediate units including (BMED2401 and BMED2403) or (BME

Assumed knowledge: 6 credit points of MBLG

Prohibitions

PHSI3907, PHSI3903, PHSI3003

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Cross-institutional study

If you are from another Australian tertiary institution you may be permitted to underake cross-institutional study in one or more units of study at the University of Sydney.

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