Dr Derek Harty

C12 - United Dental Hospital
The University of Sydney

Telephone 61 2 9845 8772
Fax 61 2 9845 7599

Website Univeristy of Sydney
Westmead Millenium Institute

Keywords

oral streptococci ; surface proteinase

Selected grants

2000

  • The role of streptococcal cell surface enzymes in carbon metabolism and pathogenisis; Harty D, Jacques N; National Health and Medical Research Council (NHMRC)/Project Grants.

Selected publications

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Journals

  • Ye, P., Harty, D., Commandeur, Z., Hunter, N. (2013). Binding of Streptococcus gordonii to oral epithelial monolayers increases paracellular barrier function. Microbial Pathogenesis, 56, 53-59. [More Information]
  • Charadram, N., Mostofi Zadeh Farahani, R., Harty, D., Rathsam, C., Swain, M., Hunter, N. (2012). Regulation of reactionary dentin formation by odontoblasts in response to polymicrobial invasion of dentin matrix. Bone, 50(1), 265-275. [More Information]
  • Harty, D., Mostofi Zadeh Farahani, R., Simonian, M., Hunter, L., Hunter, N. (2012). Streptococcus gordonii FSS2 Challisin affects fibrin clot formation by digestion of the aC region and cleavage of the N-terminal region of the BB chains of fibrinogen. Thrombosis and Haemostasis, 108(2), 236-246. [More Information]
  • Harty, D., Hunter, N. (2011). Carboxypeptidase activity common to viridans group steptococci cleaves angiotensin I to angiotensin II: an activity homologous to angiotensin-converting enzyme (ACE). Microbiology, 157(7), 2143-2151. [More Information]
  • Nadkarni, M., Simonian, M., Harty, D., Zoellner, H., Jacques, N., Hunter, N. (2010). Lactobacilli Are Prominent in the Initial Stages of Polymicrobial Infection of Dental Pulp. Journal of Clinical Microbiology, 48(5), 1732-1740. [More Information]
  • Langley, D., Harty, D., Jacques, N., Hunter, N., Guss, J., Collyer, C. (2008). Structure of N-acetyl-B-D-glucosaminidase (GcnA) from the Endocarditis Pathogen Streptococcus gordonii and its Complex with the Mechanism-based Inhibitor NAG-thiazoline. Journal of Molecular Biology, 377, 104-116. [More Information]
  • Rathsam, C., Eaton, R., Simpson, C., Browne, G., Valova, V., Harty, D., Jacques, N. (2005). Two-dimensional fluorescence difference gel electrophoretic analysis of streptococcus mutans biofilms. Journal of Proteome Research, 4(6), 2161-2173.
  • Rathsam, C., Eaton, R., Simpson, C., Browne, G., Berg, T., Harty, D., Jacques, N. (2005). Up-regulation of competence- but not stress-responsive proteins accompanies an altered metabolic phenotype in Streptococcus mutans biofilms. Microbiology, 151, 1823-1837.
  • Langley, D., Harty, D., Graham, S., Guss, J., Hunter, N., Collyer, C. (2004). Crystallization Of Gcna, An N-Acetyl-β-D-Glucosaminidase, From Streptococcus Gordonii. Acta Crystallographica. Section D: Biological Crystallography, D60, 1910-1911.
  • Len, A., Cordwell, S., Harty, D., Jacques, N. (2003). Cellular and extracellular proteome analysis of Streptococcus mutans grown in a chemostat. Proteomics, 3(5), 627-646. [More Information]
  • Ye, P., Harty, D., Chapple, C., Nadkarni, M., DeCarlo, A., Hunter, N. (2003). Streptococci and Actinomyces induce antibodies which cross react with epithelial antigens in periodontitis. Clinical and Experimental Immunology, 131(3), 468-476.

2013

  • Ye, P., Harty, D., Commandeur, Z., Hunter, N. (2013). Binding of Streptococcus gordonii to oral epithelial monolayers increases paracellular barrier function. Microbial Pathogenesis, 56, 53-59. [More Information]

2012

  • Charadram, N., Mostofi Zadeh Farahani, R., Harty, D., Rathsam, C., Swain, M., Hunter, N. (2012). Regulation of reactionary dentin formation by odontoblasts in response to polymicrobial invasion of dentin matrix. Bone, 50(1), 265-275. [More Information]
  • Harty, D., Mostofi Zadeh Farahani, R., Simonian, M., Hunter, L., Hunter, N. (2012). Streptococcus gordonii FSS2 Challisin affects fibrin clot formation by digestion of the aC region and cleavage of the N-terminal region of the BB chains of fibrinogen. Thrombosis and Haemostasis, 108(2), 236-246. [More Information]

2011

  • Harty, D., Hunter, N. (2011). Carboxypeptidase activity common to viridans group steptococci cleaves angiotensin I to angiotensin II: an activity homologous to angiotensin-converting enzyme (ACE). Microbiology, 157(7), 2143-2151. [More Information]

2010

  • Nadkarni, M., Simonian, M., Harty, D., Zoellner, H., Jacques, N., Hunter, N. (2010). Lactobacilli Are Prominent in the Initial Stages of Polymicrobial Infection of Dental Pulp. Journal of Clinical Microbiology, 48(5), 1732-1740. [More Information]

2008

  • Langley, D., Harty, D., Jacques, N., Hunter, N., Guss, J., Collyer, C. (2008). Structure of N-acetyl-B-D-glucosaminidase (GcnA) from the Endocarditis Pathogen Streptococcus gordonii and its Complex with the Mechanism-based Inhibitor NAG-thiazoline. Journal of Molecular Biology, 377, 104-116. [More Information]

2005

  • Rathsam, C., Eaton, R., Simpson, C., Browne, G., Valova, V., Harty, D., Jacques, N. (2005). Two-dimensional fluorescence difference gel electrophoretic analysis of streptococcus mutans biofilms. Journal of Proteome Research, 4(6), 2161-2173.
  • Rathsam, C., Eaton, R., Simpson, C., Browne, G., Berg, T., Harty, D., Jacques, N. (2005). Up-regulation of competence- but not stress-responsive proteins accompanies an altered metabolic phenotype in Streptococcus mutans biofilms. Microbiology, 151, 1823-1837.

2004

  • Langley, D., Harty, D., Graham, S., Guss, J., Hunter, N., Collyer, C. (2004). Crystallization Of Gcna, An N-Acetyl-β-D-Glucosaminidase, From Streptococcus Gordonii. Acta Crystallographica. Section D: Biological Crystallography, D60, 1910-1911.

2003

  • Len, A., Cordwell, S., Harty, D., Jacques, N. (2003). Cellular and extracellular proteome analysis of Streptococcus mutans grown in a chemostat. Proteomics, 3(5), 627-646. [More Information]
  • Ye, P., Harty, D., Chapple, C., Nadkarni, M., DeCarlo, A., Hunter, N. (2003). Streptococci and Actinomyces induce antibodies which cross react with epithelial antigens in periodontitis. Clinical and Experimental Immunology, 131(3), 468-476.

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