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Professor Andrew Ruys

BE PhD UNSW
Director of Biomedical Engineering (Education)
Website Centre for Advanced Materials Technology

Biomechanical, biomaterials and tissue engineering

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Biographical details

"Biomedical engineering is one of the fastest growing branches of engineering in the world today," says Professor Andrew Ruys, the coordinator and head of Biomedical Engineering at the University of Sydney.

Professor Ruys has been involved in advanced ceramics and biomaterials research for over 20 years, with a special focus on bioactive materials - those capable of forming a chemical bond with tissues in the body.
He has some 160 career publications covering a wide range of topics, including biomaterials synthesis and testing, biomaterial-cell interactions, nanocomposites, functionally graded materials, hydroxyapatite, bioglass, bioactive coatings, ceramic phase equilibria, and ceramic forming techniques. He is a world authority on hydroxyapatite bioceramics, having achieved a number of world firsts with this promising bioactive bioceramic.

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Teaching and supervision

AMME4992 - Regulatory Affairs in the Medical Industry
AMME5921 - Biomedical Engineering Technology 2
AMME5951 - Fundamentals of Neuromodulation
AMME5961 - Biomaterials Engineering
ENGG1960 - Introduction to Biomedical Engineering
MECH3921 - Biomedical Design and Technology
MECH4902 - Orthopaedic and Surgical Engineering
MECH4961 - Biomechanics and Biomaterials

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Awards and honours

  • Sydney University Dean's Award for Teaching Service, 2005
  • ARC Queen Elizabeth II Fellowship, 2001
  • U2000 Fellowship, University of Sydney, 1997
  • ARC Postdoctoral Research Fellowship, 1994
  • Finalist, Channel Ten Young Achiever Awards, Science and Technology, 1990
  • Alcan Bicentennial Research Award, 1988
  • Commonwealth Postgraduate Research Award, 1987
  • The BHP Company Prize for Best Honours Thesis Project, 1986

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Selected grants

2012

  • Pre-clinical validation of a novel implant for bone tissue engineering; Little D, Cooper-White J, Ruys A, Schindeler A; National Health and Medical Research Council/Project Grants.

2010

  • Porous refractory carbides; Ruys A; Australian Institute of Nuclear Science and Engineering/Awards.
  • Facilities of Thermophysical Characterizations at Nanometre Scale for Development of Advanced Materials, Energy Technologies and Biomedical Components; Li S, Zheng R, Ruys A; Australian Research Council/Linkage Infrastructure, Equipment and Facilities (LIEF).

2008

  • High-Resolution Field Emission Scanning Electron Microscopy (FESEM) Platform for Characterisation at the Nanometre-Level; Cairney J, Ringer S, Braet F, Ferry M, Sorrell C, Ye L, Ruys A, Barton G, Harris A, Ranzi G, Eggleton B, Grillet C, Mckenzie D, Lay P, Masters A, Parker A, Overall R, Weiss A, Murphy C, Ramzan I, Copeland L, Potts D; Australian Research Council (ARC)/Linkage Infrastructure, Equipment and Facilities (LIEF).
  • Computer simulation techniques to reduce the incidence of femoral fracture after hip replacement surgery; Appleyard R, Jim C, Ruys A, Li Q, Swain M; Australian Research Council (ARC)/Linkage Projects (LP).
  • High Resolution Field Emission Scanning Electron Microscopy (FESEM) Platform for Characterisation at; Ringer S, Barton G, Ramzan I, Copeland L, Potts D, Braet F, Grillet C, Lay P, Murphy C, Cairney J, Ferry M, Eggleton B, McKenzie D, Masters A, Parker A, Overall R, Weiss A, Ruys A, Sorrell C, Ye L, Harris A, Ranzi G; Australian Research Council (ARC)/Linkage Infrastructure, Equipment and Facilities (LIEF).

2007

  • Cochlear implants: Identifying current paths through computational modelling of MRI data; Warfield S, Carter D, Patrick J, Carter P, Ruys A, Li Q, Li W, Carter P, Warfield S; Australian Research Council (ARC)/Linkage.

2006

  • Oxide Bioceramics for Drug Delivery; Ruys A, Mason R; Australian Research Council (ARC)/Linkage (APAI only).
  • Development of biocompatible fibre-reinforced polymer biomaterial; Ruys A; University of Sydney/Early Career Researcher.

2004

  • Functionally graded fibre-polymer composites: a novel material for spinal disk prostheses; Ruys A, Mason R, Rohanizadeh R; Australian Research Council (ARC)/Linkage.
  • Surface engineering of biomaterials for optimal bone bonding characteristics; Yin Y, Martin P, Ruys A, Mason R, Rohanizadeh R; Australian Research Council (ARC)/Linkage (APAI only).
  • Fibre-Polymer Composites With Graded Microstructure; Ruys A; Australian Research Council (ARC)/Linkage (APAI only).
  • Integrated Precision Machining of Complex Profiles; Mathew P, Zhang L, Mai Y, Ye L, Ruys A, Zarudi I, Tieu K, Zhang N, Arsecularatne J, Jiang Z; Australian Research Council (ARC)/LIEF.

2002

  • Ceramic matrix nanocomposites; Ruys A; Australian Research Council (ARC)/Discovery Projects (DP).
  • Metal-Infiltrated Graded Ceramics; Ruys A; University of Sydney (Sesqui)/Research & Development.

2001

  • Functionally Graded Materials by Thermoplastic Freeze-Casting; Ruys A, Swain M; Australian Research Council (ARC)/Large Research Grant.
  • Functionally graded ceramic composites; Ruys A; Australian Research Council (ARC)/Australian Research Fellowship/Queen Elizabeth II Fellowship.

2000

  • Nanocomposite ceramics with a graded nanostructure; Ruys A; University of Sydney/University Research Grant.
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Selected publications

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Book Chapters

  • Chan, M., Ruys, A. (2006). Carbon-Fibre-Reinforced Low Thermal Expansion Ceramic Matrix Composites. In Andrew Wereszczak (Editor), Edgar Lara-Curzio (Editor), Dongming Zhu (Editor), U (Eds.), Advanced Ceramic Coatings and Interfaces, Ceramic Engineering and Science Proceedings, (pp. 305-309). USA: Wiley.
  • Chavara, D., Ruys, A. (2006). Development of the Impeller-Dry-Blending Process for the Fabrication of Metal-Ceramic functionally graded materials. In Andrew Wereszczak (Editor), Edgar Lara-Curzio (Editor), Dongming Zhu (Editor), U (Eds.), Advanced Ceramic Coatings and Interfaces, Ceramic Engineering and Science Proceedings, (pp. 311-319). USA: Wiley.

Journals

  • Carr, D., Yu, N., Fitzpatrick, J., Peacock, L., Mikulec, K., Ruys, A., Cooper-White, J., Little, D., Schindeler, A. (2013). Synergy between rhBMP-2 and IKK-Inhibitor PS-1145 Delivered via a Porous Biodegradable Polymer Implant. Journal of Tissue Science and Engineering, (S:1), 1-7.
  • Poon, C., Zhang, M., Ruys, A., Hong, A., Catuogno, C., Boughton, P. (2012). A Novel Dynamic 3-Dimensional Construct for Respiratory Tissue Engineering. Journal of Biomimetics, Biomaterials, and Tissue Engineering, 14, 31-42.
  • Chan, A., Young, N., Tran, G., Miles, B., Ruys, A., Boughton, P. (2012). A Novel Patient-Specific Regenerative Meniscal Replacement System. Journal of Biomimetics, Biomaterials, and Tissue Engineering, 16, 83-95.
  • Chow, B., Baume, A., Lok, P., Cao, Y., Coleman, N., Ruys, A., Boughton, P. (2012). Development of 3D Antibiotic-Eluting Bioresorbable Scaffold with Attenuating Envelopes. Journal of Biomimetics, Biomaterials, and Tissue Engineering, 15, 2012, 55-62.
  • Mehzabeen, K., Sureshkumar, A., Thangavel, A., Chong, B., Guazzato, M., Ruys, A., Boughton, P. (2012). Development of a Novel Biomimetic Dental Wear System. Journal of Biomimetics, Biomaterials, and Tissue Engineering, 15, 23-35.
  • Yu, N., Schindeler, A., Tagil, M., Ruys, A., Little, D. (2012). Use of BMPs and bisphosphonates to improve bone fracture healing. Frontiers in Bioscience (Elite Edition), 4E, 2647-2653.
  • Zhang, S., Awaja, F., James, N., McKenzie, D., Ruys, A. (2011). A comparison of the strength of autohesion of plasma treated amorphous and semi-crystalline PEEK films. Polymers for Advanced Technologies, 22(12), 2496-2502.
  • Zhang, S., Awaja, F., James, N., McKenzie, D., Ruys, A. (2011). Autohesion of plasma treated semi-crystalline PEEK: Comparative study of argon, nitrogen and oxygen treatments. Colloids and Surfaces A-Physicochemical and Engineering Aspects, 374(1-3), 88-95.
  • Boughton, P., Chen, Y., Thompson, C., Roger, G., Hyvarinen, J., Ruys, A. (2011). Development of a Bioabsorbable Glass-Reinforced-Glass Intra-Osseous Scaffold for Fracture Healing. Journal of Biomimetics, Biomaterials, and Tissue Engineering, 9, 81-91.
  • Schindeler, A., Birke, O., Yu, N., Morse, A., Ruys, A., Baldock, P., Little, D. (2011). Distal tibial fracture repair in a neurofibromatosis type 1-deficient mouse treated with recombinant bone morphogenetic protein and a bisphosphonate. Journal of Bone and Joint Surgery: British Volume, 93 B (8), 1134-1139.
  • Zhong, X., Ji, C., Chan, A., Kazarian, S., Ruys, A., Dehghani, F. (2011). Fabrication of chitosan/poly(epsilon-caprolactone) composite hydrogels for tissue engineering applications. Journal of Materials Science: Materials in Medicine, 22(2), 279-288.
  • Maddock (nee Amanat), N., Nicoll, A., Ruys, A., McKenzie, D., James, N. (2011). Gas permeability reduction in PEEK film: Comparison of tetrahedral amorphous carbon and titanium nanofilm coatings. Journal of Membrane Science, 378(1-2), 265-271.
  • Ilkin, S., Chaves, A., Ruys, A., Fraser, D. (2011). In vitro solubilisation and mechanical kinetics of cooked versus uncooked bones. Australian Veterinary Practitioner, 41(2), 66-69.
  • Lau, H., Ruys, A., Carter, P., Wang, X., Li, Q. (2011). Subject Specific Modelling of Electrical Conduction in the Body: a Case Study. Journal of Biomimetics, Biomaterials, and Tissue Engineering, 10, 43-53.
  • Zhang, S., Awaja, F., James, N., McKenzie, D., Ruys, A. (2010). A comparison of the strength of autohesion of plasma treated amorphous and semi-crystalline PEEK films. Polymers for Advanced Technologies, Published online 2010, 1-7.
  • Boughton, P., Merhebi, J., Kim, C., Roger, G., Diwan, A., Clarke, E., Maddock (nee Amanat), N., Ho, R., Ruys, A. (2010). An Interlocking Ligamentous Spinal Disk Arthroplasty with Neural Network Infrastructure. Journal of Biomimetics, Biomaterials, and Tissue Engineering, 7, 55-79.
  • Yu, N., Schindeler, A., Little, D., Ruys, A. (2010). Biodegradable poly(alpha-hydroxy acid) polymer scaffolds for bone tissue engineering. Journal of Biomedical Materials Research. Part B: Applied Biomaterials, 93B(1), 285-295.
  • Zhong, X., Ji, C., Chan, A., Kazarian, S., Ruys, A., Dehghani, F. (2010). Fabrication of chitosan/poly(ε-caprolactone) composite hydrogels for tissue engineering applications. Journal of Materials Science: Materials in Medicine, , 1-10.
  • Ma, Y., Bryce, N., Whan, R., Xiao, L., Li, K., Ruys, A., Hambley, T., Boughton, P. (2010). Growth of DLD-1 Colon Cancer Cells on Variotis™ Scaffolds of Controlled Porosity: A Preliminary Study. Journal of Biomimetics, Biomaterials, and Tissue Engineering, 8, 79-89.
  • Yu, N., Schindeler, A., Peacock, L., Mikulec, K., Baldock, P., Ruys, A., Little, D. (2010). In vivo local co-delivery of recombinant human bone morphogenetic protein-7 and pamidronate via poly-D, L-lactic acid. European Cells and Materials, 20, 431-442.
  • Schindeler, A., Morse, A., Peacock, L., Mikulec, K., Yu, N., Liu, R., Kijumnuayporn, S., McDonald, M., Baldock, P., Ruys, A., Little, D. (2010). Rapid cell culture and pre-clinical screening of a transforming growth factor-beta (TGF-beta) inhibitor for orthopaedics. BMC Musculoskeletal Disorders, 11(105), 105-1-105-9.
  • Chan, M., Ruys, A. (2010). Sintering Studies of Carbon Fibre-Reinforced Fused Silica for High-Temperature Applications. Interceram, 59(1), 18-20.
  • Chan, M., Ruys, A. (2009). Biomimetic Design of Haute-Temperature Lightweight Ceramics- A Review. Journal of Biomimetics, Biomaterials, and Tissue Engineering, 2, 124-92.
  • Chavara, D., Wang, C., Ruys, A. (2009). Biomimetic Functionally Graded Materials: Synthesis by Impeller-Dry-Blending. Journal of Biomimetics, Biomaterials, and Tissue Engineering, 3, 37-49.
  • Soh, E., Ruys, A. (2009). Characterisation of Foamed Porous Alumina Tissue Scaffolds. Journal of Biomimetics, Biomaterials, and Tissue Engineering, 4, 21-26.
  • Liyanage, S., Boughton, P., Roger, G., Hyvarinen, J., Ruys, A. (2009). Design Review & Preliminary Testing For A Biomimetic Absorbable Ligament Anchor. Journal of Biomimetics, Biomaterials, and Tissue Engineering, 4, 71-95.
  • Annabi, N., Mithieux, S., Boughton, E., Ruys, A., Weiss, A., Dehghani, F. (2009). Synthesis of highly porous crosslinked elastin hydrogels and their interaction with fibroblasts in vitro. Biomaterials, 30(27), 4550-4557.
  • Yu, N., Ruys, A., Zenios, M., Godfrey, C., McDonald, M., Kiely, P., Mikulec, K., Little, D., Schindeler, A. (2008). Bisphosphonate-Laden Acrylic Bone Cement: Mechanical Properties, Elution Performance, and In Vivo Activity. Journal of Biomedical Materials Research. Part B: Applied Biomaterials, 87B(2), 482-491.
  • Wong, C., Ruys, A., Cairney, J. (2008). Freeze-Dried Nanoparticulate Sols. Materials Forum, 32, 78-81.
  • Ma, W., Ruys, A., Mason, R., Martin, P., Bendavid, A., Liu, Z., Ionescu, M., Zreiqat, H. (2007). DLC coatings: Effects of physical and chemical properties on biological response. Biomaterials, 28(9), 1620-1628.
  • Hamzaid, N., Fornusek, C., Ruys, A., Davis, G. (2007). Mechanical design and driving mechanism of an isokinetic functional electrical stimulation-based leg stepping trainer. Australasian Physical and Engineering Sciences in Medicine, 30(4), 323-326.
  • Kolos, E., Ruys, A., Rohanizadeh, R., Muir, M., Roger, G. (2006). Calcium phosphate fibres synthesized from a simulated body fluid. Journal of Materials Science: Materials in Medicine, 17(11), 1179-1189.
  • Ma, W., Ruys, A., Mason, R., Martin, P., Bendavid, A., Liu, Z., Ionescu, M., Zreiqat, H. (2006). DLC coatings: Effects of physical and chemical properties on biological response. Biomaterials, 28(9), 1620-1628.
  • Boughton, P., Ruys, A., Roger, G., Rohanizadeh, R., Fisher, S., Kolos, E. (2006). Functionally graded material for a spinal disk prosthesis. Australasian Physical and Engineering Sciences in Medicine, 29(1), 107.
  • Magdon Ismail, F., Rohanizadeh, R., Atwa, S., Mason, R., Ruys, A., Martin, P., Bendavid, A. (2006). The influence of surface chemistry and topography on the contact guidance of MG63 Osteoblast cells. Journal of Materials Science: Materials in Medicine, 18(5), 705-714.
  • Kolos, E., Ruys, A., Rohanizadeh, R., Muir, M., Roger, G. (2005). Biomimetic Hydroxyapatite Micro-Tube Tissue Scaffold. Key Engineering Materials, 284-286, 643-646.
  • Wei, M., Ruys, A., Swain, M., Milthorpe, B., Sorrell, C. (2005). Hydroxyapatite-coated metals: Interfacial reactions during sintering. Journal of Materials Science: Materials in Medicine, 16(2), 101-106.
  • Wei, M., Ruys, A., Milthorpe, B., Sorrell, C. (2005). Precipitation of hydroxyapatite nanoparticles: Effects of precipitation method on electrophoretic deposition. Journal of Materials Science: Materials in Medicine, 16(4), 319-324.
  • Kolos, E., Ruys, A., Rohanizadeh, R., Muir, M., Roger, G. (2004). Hydroxyapatite Fibres Synthesized From A Simulated Body Fluid: Surface Morphology And Cell Attachment Characteristics. Australasian Ceramic Society. Journal, 40(2), 28-32.
  • Kolos, E., Ruys, A., Rohanizadeh, R., Muir, M., Roger, G. (2004). Novel Calcium Phosphate Fibres From A Biomimetic Process: Manufacture And Cell Attachment. Key Engineering Materials, 254, 343-346.
  • Kolos, E., Ruys, A., Roger, G. (2003). A Novel Biomimetic Approach for the Manufacture of Hydroxyapatite Fibres. Key Engineering Materials, 240-242, 47-50.
  • Wei, T., Ruys, A., Milthorpe, B. (2003). Hydroxyapatite-Zirconia Functionally Graded Bioceramics Prepared by Hot Isostatic Pressing. Key Engineering Materials, 240-242, 591-594.
  • Ruys, A., Lee, T., Russell, J. (2002). Processing of homogeneous nanocomposites. Materials Integration, , 51-57.
  • Ruys, A., Wei, M., Milthorpe, B., Sorrell, C., Evans,, J. (2001). Electrophoretic deposition of hydroxyapatite coatings on metal substrates: A nanoparticulate dual-coating approach. Journal of Sol-Gel Science and Technology, 21, 39-48.
  • Ruys, A., Popov, E., Sun, D., Russell, J., Murray, C. (2001). Functionally graded electrical/thermal ceramic systems. Journal of the European Ceramic Society, 21, 2025-2029.
  • Ruys, A., Miao,, X., Milthorpe, B. (2001). Hydroxyapatite-316L fibre composites prepared by vibration assisted slip casting. Journal of Materials Science, 36, 3323-3332.

Conferences

  • Zhong, X., Ji, C., Kazarian, S., Ruys, A., Dehghani, F. (2010). Chitosan/Poly (e-Caprolactone) Composite Hydrogel for Tissue Engineering Applications. The 26th Southern Biomedical Engineering Conference, United States: Springer.
  • Hamzaid, N., Fornusek, C., Ruys, A., Davis, G. (2009). Development of an Isokinetic FES Leg Stepping Trainer (iFES-LST) for Individuals with Neurological Disability. 2009 IEEE 11th International Conference on Rehabilitation Robotics (ICORR2009), Japan/online: (IEEE) Institute of Electrical and Electronics Engineers.
  • Chen, K., Li, Q., Li, W., Lau, H., Ruys, A., Carter, P. (2009). Three-Dimensional finite element modeling of cochlear implant induced electrical current flows. IEEE International Conference on Computational Intelligence for Measurement Systems and Applications CIMSA 2009, United States: (IEEE) Institute of Electrical and Electronics Engineers.
  • Kim, I., Hamzaid, N., Ruys, A., Davis, G. (2007). Design considerations of lower limb support for elliptical stepping exercise by spinal cord injured individuals. Fifth Australasian Congress on Applied Mechanics (ACAM 2007), Brisbane, Australia: Engineers Australia.
  • Liew, C., Veidt, M., Chavara, D., Ruys, A., young, C., McCreery, M. (2007). Metal-Polymer functionally graded materials for removing guided wave reflections at beam end boundaries. Fifth Australasian Congress on Applied Mechanics (ACAM 2007), Brisbane, Australia: Engineers Australia.
  • Chan, M., Ruys, A. (2006). Carbon-Fibre-Reinforced Ceramic Matrix Composites for High-Temperature Applications. 44th AIAA Aerospace Sciences Meeting and Exhibit, Reston, VA, USA: American Institute of Aeronautics and Astronautics (AIAA).
  • Hamzaid, N., Fornusek, C., Ruys, A., Davis, G. (2006). Conceptual Design of an Isokinetic Functional Electrical Stimulation (FES) Leg Stepping Trainer for Individuals with Neurological Disability. Kuala Lumpur International Conference on Biomedical Engineering (Biomed) 2006, Malaysia: Department of Biomedical Engineering, University of Malaya, Malaysia.
  • Chavara, D., Ruys, A. (2006). Fabrication of Metal-Ceramic Functionally Graded Materials for Use as Heat Sheild Tiles. 44th AIAA Aerospace Sciences Meeting and Exhibit, Reston, VA, USA: American Institute of Aeronautics and Astronautics (AIAA).
  • Ma, W., Ruys, A., Zreiqat, H., Mason, R., Ringer, S., Liu, Z., Keast, V., Martin, P., Bendavid, A. (2006). The Biocompatibility of Diamond-Like Carbon Nano Films. International Conference on Nanoscience and Nanotechnology 2006, Brisbane, Australia: (IEEE) Institute of Electrical and Electronics Engineers.
  • Chan, M., Ruys, A. (2005). Carbon-fibre-reinforced ceramic matrix composites for high-temperature applications. AIAA-2006-1491, : American Institute of Aeronautics and Astronautics (AIAA).
  • Ma, W., Ruys, A., Mason, R., Zreiqat, H., Cheung, W., Wong, S., Martin, P., Bendavid, A., Keast, V. (2005). Effect of composition of diamond-like carbon films on surface properties and biocompatibility. The 12th International Conference on Biomedical Engineering - ICBMEC 2005, CD-ROM: IFMBE.
  • Chavara, D., Ruys, A. (2005). Fabrication of metal-ceramic functionally graded materials for use as heat shield tiles. AIAA-2006-1490, : American Institute of Aeronautics and Astronautics (AIAA).
  • Soh, E., Ruys, A., Parakala, P. (2005). Foamed alumina bioceramics for use as tissue scaffolds. The 12th International Conference on Biomedical Engineering - ICBMEC 2005, CD-ROM: IFMBE.
  • Magdon Ismail, F., Ruys, A., Rohanizadeh, R., Martin, P., Bendavid, A. (2005). The effect of surface chemistry and topography on MG63 osteoblast cells to biomaterials. 2A3-10, : IFMBE.
  • West, M., Ruys, A., Bosi, S. (2005). The effect of the ultraviolet radiation environment of LEO upon polycarbonate materials. 43rd AIAA Aerospace Sciences Meeting & Exhibit, USA: American Institute of Aeronautics and Astronautics (AIAA).
  • West, M., Ruys, A., Bosi, S. (2005). The interaction of the ultraviolet radiation environment of space upon polycarbonate materials. AIAC - 11th Australian International Aerospace Congress, Melbourne, Australia: Institution of Engineers Australia.
  • Kolos, E., Ruys, A., Rohanizadeh, R., Muir, M., Roger, G. (2004). Cell Attachment On Novel Biomimetic Calcium Phosphate Materials. 7th World Biomaterials Congress, CD: Association Historique Internationale de l'Ocan Indien.
  • Kolos, E., Ruys, A., Rohanizadeh, R., Muir, M., Roger, G. (2004). Ha Fibre Compact Bone Filler Manufactured From Novel Ha Fibres Synthesized From A Simulated Body Fluid. 17th Annual Meeting of the International Society for Ceramics in Medicine (ISCM), Online: Science Press.
  • Garcia, C., Davis, G., Ruys, A. (2002). Development of an asynchronous-elliptical FES cycling system for paraplegics. Third College of Health Sciences Research Conference 2002 : from cell to society 3, Sydney: University of Sydney.
  • Boughton, P., Ferris, D., Ruys, A. (2001). A ceramic-polymer functionally graded material: a material with potential as a spinal disk prosthesis. ACUN-3 International Composites Conference: Technology Convergence in Composites Applications, Sydney: UNSW Australian Defence Force Academy.
  • Boughton, P., Ferris, D., Ruys, A. (2001). A ceramic-polymer functionally graded material: A novel disk prosthesis. 25th International Conference on Advanced Ceramics and Composites, Cocoa Beach, Florida: American Ceramic Society Inc.

2013

  • Carr, D., Yu, N., Fitzpatrick, J., Peacock, L., Mikulec, K., Ruys, A., Cooper-White, J., Little, D., Schindeler, A. (2013). Synergy between rhBMP-2 and IKK-Inhibitor PS-1145 Delivered via a Porous Biodegradable Polymer Implant. Journal of Tissue Science and Engineering, (S:1), 1-7.

2012

  • Poon, C., Zhang, M., Ruys, A., Hong, A., Catuogno, C., Boughton, P. (2012). A Novel Dynamic 3-Dimensional Construct for Respiratory Tissue Engineering. Journal of Biomimetics, Biomaterials, and Tissue Engineering, 14, 31-42.
  • Chan, A., Young, N., Tran, G., Miles, B., Ruys, A., Boughton, P. (2012). A Novel Patient-Specific Regenerative Meniscal Replacement System. Journal of Biomimetics, Biomaterials, and Tissue Engineering, 16, 83-95.
  • Chow, B., Baume, A., Lok, P., Cao, Y., Coleman, N., Ruys, A., Boughton, P. (2012). Development of 3D Antibiotic-Eluting Bioresorbable Scaffold with Attenuating Envelopes. Journal of Biomimetics, Biomaterials, and Tissue Engineering, 15, 2012, 55-62.
  • Mehzabeen, K., Sureshkumar, A., Thangavel, A., Chong, B., Guazzato, M., Ruys, A., Boughton, P. (2012). Development of a Novel Biomimetic Dental Wear System. Journal of Biomimetics, Biomaterials, and Tissue Engineering, 15, 23-35.
  • Yu, N., Schindeler, A., Tagil, M., Ruys, A., Little, D. (2012). Use of BMPs and bisphosphonates to improve bone fracture healing. Frontiers in Bioscience (Elite Edition), 4E, 2647-2653.

2011

  • Zhang, S., Awaja, F., James, N., McKenzie, D., Ruys, A. (2011). A comparison of the strength of autohesion of plasma treated amorphous and semi-crystalline PEEK films. Polymers for Advanced Technologies, 22(12), 2496-2502.
  • Zhang, S., Awaja, F., James, N., McKenzie, D., Ruys, A. (2011). Autohesion of plasma treated semi-crystalline PEEK: Comparative study of argon, nitrogen and oxygen treatments. Colloids and Surfaces A-Physicochemical and Engineering Aspects, 374(1-3), 88-95.
  • Boughton, P., Chen, Y., Thompson, C., Roger, G., Hyvarinen, J., Ruys, A. (2011). Development of a Bioabsorbable Glass-Reinforced-Glass Intra-Osseous Scaffold for Fracture Healing. Journal of Biomimetics, Biomaterials, and Tissue Engineering, 9, 81-91.
  • Schindeler, A., Birke, O., Yu, N., Morse, A., Ruys, A., Baldock, P., Little, D. (2011). Distal tibial fracture repair in a neurofibromatosis type 1-deficient mouse treated with recombinant bone morphogenetic protein and a bisphosphonate. Journal of Bone and Joint Surgery: British Volume, 93 B (8), 1134-1139.
  • Zhong, X., Ji, C., Chan, A., Kazarian, S., Ruys, A., Dehghani, F. (2011). Fabrication of chitosan/poly(epsilon-caprolactone) composite hydrogels for tissue engineering applications. Journal of Materials Science: Materials in Medicine, 22(2), 279-288.
  • Maddock (nee Amanat), N., Nicoll, A., Ruys, A., McKenzie, D., James, N. (2011). Gas permeability reduction in PEEK film: Comparison of tetrahedral amorphous carbon and titanium nanofilm coatings. Journal of Membrane Science, 378(1-2), 265-271.
  • Ilkin, S., Chaves, A., Ruys, A., Fraser, D. (2011). In vitro solubilisation and mechanical kinetics of cooked versus uncooked bones. Australian Veterinary Practitioner, 41(2), 66-69.
  • Lau, H., Ruys, A., Carter, P., Wang, X., Li, Q. (2011). Subject Specific Modelling of Electrical Conduction in the Body: a Case Study. Journal of Biomimetics, Biomaterials, and Tissue Engineering, 10, 43-53.

2010

  • Zhang, S., Awaja, F., James, N., McKenzie, D., Ruys, A. (2010). A comparison of the strength of autohesion of plasma treated amorphous and semi-crystalline PEEK films. Polymers for Advanced Technologies, Published online 2010, 1-7.
  • Boughton, P., Merhebi, J., Kim, C., Roger, G., Diwan, A., Clarke, E., Maddock (nee Amanat), N., Ho, R., Ruys, A. (2010). An Interlocking Ligamentous Spinal Disk Arthroplasty with Neural Network Infrastructure. Journal of Biomimetics, Biomaterials, and Tissue Engineering, 7, 55-79.
  • Yu, N., Schindeler, A., Little, D., Ruys, A. (2010). Biodegradable poly(alpha-hydroxy acid) polymer scaffolds for bone tissue engineering. Journal of Biomedical Materials Research. Part B: Applied Biomaterials, 93B(1), 285-295.
  • Zhong, X., Ji, C., Kazarian, S., Ruys, A., Dehghani, F. (2010). Chitosan/Poly (e-Caprolactone) Composite Hydrogel for Tissue Engineering Applications. The 26th Southern Biomedical Engineering Conference, United States: Springer.
  • Zhong, X., Ji, C., Chan, A., Kazarian, S., Ruys, A., Dehghani, F. (2010). Fabrication of chitosan/poly(ε-caprolactone) composite hydrogels for tissue engineering applications. Journal of Materials Science: Materials in Medicine, , 1-10.
  • Ma, Y., Bryce, N., Whan, R., Xiao, L., Li, K., Ruys, A., Hambley, T., Boughton, P. (2010). Growth of DLD-1 Colon Cancer Cells on Variotis™ Scaffolds of Controlled Porosity: A Preliminary Study. Journal of Biomimetics, Biomaterials, and Tissue Engineering, 8, 79-89.
  • Yu, N., Schindeler, A., Peacock, L., Mikulec, K., Baldock, P., Ruys, A., Little, D. (2010). In vivo local co-delivery of recombinant human bone morphogenetic protein-7 and pamidronate via poly-D, L-lactic acid. European Cells and Materials, 20, 431-442.
  • Schindeler, A., Morse, A., Peacock, L., Mikulec, K., Yu, N., Liu, R., Kijumnuayporn, S., McDonald, M., Baldock, P., Ruys, A., Little, D. (2010). Rapid cell culture and pre-clinical screening of a transforming growth factor-beta (TGF-beta) inhibitor for orthopaedics. BMC Musculoskeletal Disorders, 11(105), 105-1-105-9.
  • Chan, M., Ruys, A. (2010). Sintering Studies of Carbon Fibre-Reinforced Fused Silica for High-Temperature Applications. Interceram, 59(1), 18-20.

2009

  • Chan, M., Ruys, A. (2009). Biomimetic Design of Haute-Temperature Lightweight Ceramics- A Review. Journal of Biomimetics, Biomaterials, and Tissue Engineering, 2, 124-92.
  • Chavara, D., Wang, C., Ruys, A. (2009). Biomimetic Functionally Graded Materials: Synthesis by Impeller-Dry-Blending. Journal of Biomimetics, Biomaterials, and Tissue Engineering, 3, 37-49.
  • Soh, E., Ruys, A. (2009). Characterisation of Foamed Porous Alumina Tissue Scaffolds. Journal of Biomimetics, Biomaterials, and Tissue Engineering, 4, 21-26.
  • Liyanage, S., Boughton, P., Roger, G., Hyvarinen, J., Ruys, A. (2009). Design Review & Preliminary Testing For A Biomimetic Absorbable Ligament Anchor. Journal of Biomimetics, Biomaterials, and Tissue Engineering, 4, 71-95.
  • Hamzaid, N., Fornusek, C., Ruys, A., Davis, G. (2009). Development of an Isokinetic FES Leg Stepping Trainer (iFES-LST) for Individuals with Neurological Disability. 2009 IEEE 11th International Conference on Rehabilitation Robotics (ICORR2009), Japan/online: (IEEE) Institute of Electrical and Electronics Engineers.
  • Annabi, N., Mithieux, S., Boughton, E., Ruys, A., Weiss, A., Dehghani, F. (2009). Synthesis of highly porous crosslinked elastin hydrogels and their interaction with fibroblasts in vitro. Biomaterials, 30(27), 4550-4557.
  • Chen, K., Li, Q., Li, W., Lau, H., Ruys, A., Carter, P. (2009). Three-Dimensional finite element modeling of cochlear implant induced electrical current flows. IEEE International Conference on Computational Intelligence for Measurement Systems and Applications CIMSA 2009, United States: (IEEE) Institute of Electrical and Electronics Engineers.

2008

  • Yu, N., Ruys, A., Zenios, M., Godfrey, C., McDonald, M., Kiely, P., Mikulec, K., Little, D., Schindeler, A. (2008). Bisphosphonate-Laden Acrylic Bone Cement: Mechanical Properties, Elution Performance, and In Vivo Activity. Journal of Biomedical Materials Research. Part B: Applied Biomaterials, 87B(2), 482-491.
  • Wong, C., Ruys, A., Cairney, J. (2008). Freeze-Dried Nanoparticulate Sols. Materials Forum, 32, 78-81.

2007

  • Kim, I., Hamzaid, N., Ruys, A., Davis, G. (2007). Design considerations of lower limb support for elliptical stepping exercise by spinal cord injured individuals. Fifth Australasian Congress on Applied Mechanics (ACAM 2007), Brisbane, Australia: Engineers Australia.
  • Ma, W., Ruys, A., Mason, R., Martin, P., Bendavid, A., Liu, Z., Ionescu, M., Zreiqat, H. (2007). DLC coatings: Effects of physical and chemical properties on biological response. Biomaterials, 28(9), 1620-1628.
  • Hamzaid, N., Fornusek, C., Ruys, A., Davis, G. (2007). Mechanical design and driving mechanism of an isokinetic functional electrical stimulation-based leg stepping trainer. Australasian Physical and Engineering Sciences in Medicine, 30(4), 323-326.
  • Liew, C., Veidt, M., Chavara, D., Ruys, A., young, C., McCreery, M. (2007). Metal-Polymer functionally graded materials for removing guided wave reflections at beam end boundaries. Fifth Australasian Congress on Applied Mechanics (ACAM 2007), Brisbane, Australia: Engineers Australia.

2006

  • Kolos, E., Ruys, A., Rohanizadeh, R., Muir, M., Roger, G. (2006). Calcium phosphate fibres synthesized from a simulated body fluid. Journal of Materials Science: Materials in Medicine, 17(11), 1179-1189.
  • Chan, M., Ruys, A. (2006). Carbon-Fibre-Reinforced Ceramic Matrix Composites for High-Temperature Applications. 44th AIAA Aerospace Sciences Meeting and Exhibit, Reston, VA, USA: American Institute of Aeronautics and Astronautics (AIAA).
  • Chan, M., Ruys, A. (2006). Carbon-Fibre-Reinforced Low Thermal Expansion Ceramic Matrix Composites. In Andrew Wereszczak (Editor), Edgar Lara-Curzio (Editor), Dongming Zhu (Editor), U (Eds.), Advanced Ceramic Coatings and Interfaces, Ceramic Engineering and Science Proceedings, (pp. 305-309). USA: Wiley.
  • Hamzaid, N., Fornusek, C., Ruys, A., Davis, G. (2006). Conceptual Design of an Isokinetic Functional Electrical Stimulation (FES) Leg Stepping Trainer for Individuals with Neurological Disability. Kuala Lumpur International Conference on Biomedical Engineering (Biomed) 2006, Malaysia: Department of Biomedical Engineering, University of Malaya, Malaysia.
  • Chavara, D., Ruys, A. (2006). Development of the Impeller-Dry-Blending Process for the Fabrication of Metal-Ceramic functionally graded materials. In Andrew Wereszczak (Editor), Edgar Lara-Curzio (Editor), Dongming Zhu (Editor), U (Eds.), Advanced Ceramic Coatings and Interfaces, Ceramic Engineering and Science Proceedings, (pp. 311-319). USA: Wiley.
  • Ma, W., Ruys, A., Mason, R., Martin, P., Bendavid, A., Liu, Z., Ionescu, M., Zreiqat, H. (2006). DLC coatings: Effects of physical and chemical properties on biological response. Biomaterials, 28(9), 1620-1628.
  • Chavara, D., Ruys, A. (2006). Fabrication of Metal-Ceramic Functionally Graded Materials for Use as Heat Sheild Tiles. 44th AIAA Aerospace Sciences Meeting and Exhibit, Reston, VA, USA: American Institute of Aeronautics and Astronautics (AIAA).
  • Boughton, P., Ruys, A., Roger, G., Rohanizadeh, R., Fisher, S., Kolos, E. (2006). Functionally graded material for a spinal disk prosthesis. Australasian Physical and Engineering Sciences in Medicine, 29(1), 107.
  • Ma, W., Ruys, A., Zreiqat, H., Mason, R., Ringer, S., Liu, Z., Keast, V., Martin, P., Bendavid, A. (2006). The Biocompatibility of Diamond-Like Carbon Nano Films. International Conference on Nanoscience and Nanotechnology 2006, Brisbane, Australia: (IEEE) Institute of Electrical and Electronics Engineers.
  • Magdon Ismail, F., Rohanizadeh, R., Atwa, S., Mason, R., Ruys, A., Martin, P., Bendavid, A. (2006). The influence of surface chemistry and topography on the contact guidance of MG63 Osteoblast cells. Journal of Materials Science: Materials in Medicine, 18(5), 705-714.

2005

  • Kolos, E., Ruys, A., Rohanizadeh, R., Muir, M., Roger, G. (2005). Biomimetic Hydroxyapatite Micro-Tube Tissue Scaffold. Key Engineering Materials, 284-286, 643-646.
  • Chan, M., Ruys, A. (2005). Carbon-fibre-reinforced ceramic matrix composites for high-temperature applications. AIAA-2006-1491, : American Institute of Aeronautics and Astronautics (AIAA).
  • Ma, W., Ruys, A., Mason, R., Zreiqat, H., Cheung, W., Wong, S., Martin, P., Bendavid, A., Keast, V. (2005). Effect of composition of diamond-like carbon films on surface properties and biocompatibility. The 12th International Conference on Biomedical Engineering - ICBMEC 2005, CD-ROM: IFMBE.
  • Chavara, D., Ruys, A. (2005). Fabrication of metal-ceramic functionally graded materials for use as heat shield tiles. AIAA-2006-1490, : American Institute of Aeronautics and Astronautics (AIAA).
  • Soh, E., Ruys, A., Parakala, P. (2005). Foamed alumina bioceramics for use as tissue scaffolds. The 12th International Conference on Biomedical Engineering - ICBMEC 2005, CD-ROM: IFMBE.
  • Wei, M., Ruys, A., Swain, M., Milthorpe, B., Sorrell, C. (2005). Hydroxyapatite-coated metals: Interfacial reactions during sintering. Journal of Materials Science: Materials in Medicine, 16(2), 101-106.
  • Wei, M., Ruys, A., Milthorpe, B., Sorrell, C. (2005). Precipitation of hydroxyapatite nanoparticles: Effects of precipitation method on electrophoretic deposition. Journal of Materials Science: Materials in Medicine, 16(4), 319-324.
  • Magdon Ismail, F., Ruys, A., Rohanizadeh, R., Martin, P., Bendavid, A. (2005). The effect of surface chemistry and topography on MG63 osteoblast cells to biomaterials. 2A3-10, : IFMBE.
  • West, M., Ruys, A., Bosi, S. (2005). The effect of the ultraviolet radiation environment of LEO upon polycarbonate materials. 43rd AIAA Aerospace Sciences Meeting & Exhibit, USA: American Institute of Aeronautics and Astronautics (AIAA).
  • West, M., Ruys, A., Bosi, S. (2005). The interaction of the ultraviolet radiation environment of space upon polycarbonate materials. AIAC - 11th Australian International Aerospace Congress, Melbourne, Australia: Institution of Engineers Australia.

2004

  • Kolos, E., Ruys, A., Rohanizadeh, R., Muir, M., Roger, G. (2004). Cell Attachment On Novel Biomimetic Calcium Phosphate Materials. 7th World Biomaterials Congress, CD: Association Historique Internationale de l'Ocan Indien.
  • Kolos, E., Ruys, A., Rohanizadeh, R., Muir, M., Roger, G. (2004). Ha Fibre Compact Bone Filler Manufactured From Novel Ha Fibres Synthesized From A Simulated Body Fluid. 17th Annual Meeting of the International Society for Ceramics in Medicine (ISCM), Online: Science Press.
  • Kolos, E., Ruys, A., Rohanizadeh, R., Muir, M., Roger, G. (2004). Hydroxyapatite Fibres Synthesized From A Simulated Body Fluid: Surface Morphology And Cell Attachment Characteristics. Australasian Ceramic Society. Journal, 40(2), 28-32.
  • Kolos, E., Ruys, A., Rohanizadeh, R., Muir, M., Roger, G. (2004). Novel Calcium Phosphate Fibres From A Biomimetic Process: Manufacture And Cell Attachment. Key Engineering Materials, 254, 343-346.

2003

  • Kolos, E., Ruys, A., Roger, G. (2003). A Novel Biomimetic Approach for the Manufacture of Hydroxyapatite Fibres. Key Engineering Materials, 240-242, 47-50.
  • Wei, T., Ruys, A., Milthorpe, B. (2003). Hydroxyapatite-Zirconia Functionally Graded Bioceramics Prepared by Hot Isostatic Pressing. Key Engineering Materials, 240-242, 591-594.

2002

  • Garcia, C., Davis, G., Ruys, A. (2002). Development of an asynchronous-elliptical FES cycling system for paraplegics. Third College of Health Sciences Research Conference 2002 : from cell to society 3, Sydney: University of Sydney.
  • Ruys, A., Lee, T., Russell, J. (2002). Processing of homogeneous nanocomposites. Materials Integration, , 51-57.

2001

  • Boughton, P., Ferris, D., Ruys, A. (2001). A ceramic-polymer functionally graded material: a material with potential as a spinal disk prosthesis. ACUN-3 International Composites Conference: Technology Convergence in Composites Applications, Sydney: UNSW Australian Defence Force Academy.
  • Boughton, P., Ferris, D., Ruys, A. (2001). A ceramic-polymer functionally graded material: A novel disk prosthesis. 25th International Conference on Advanced Ceramics and Composites, Cocoa Beach, Florida: American Ceramic Society Inc.
  • Ruys, A., Wei, M., Milthorpe, B., Sorrell, C., Evans,, J. (2001). Electrophoretic deposition of hydroxyapatite coatings on metal substrates: A nanoparticulate dual-coating approach. Journal of Sol-Gel Science and Technology, 21, 39-48.
  • Ruys, A., Popov, E., Sun, D., Russell, J., Murray, C. (2001). Functionally graded electrical/thermal ceramic systems. Journal of the European Ceramic Society, 21, 2025-2029.
  • Ruys, A., Miao,, X., Milthorpe, B. (2001). Hydroxyapatite-316L fibre composites prepared by vibration assisted slip casting. Journal of Materials Science, 36, 3323-3332.
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