Professor Fariba Dehghani
School of Chemical and Biomolecular Engineering
Heading a multidisciplinary research group, Professor Fariba Dehghani leads a prominent team of researchers in the field of bioengineering. This team encompasses a wide spectrum of expertise, including postgraduates, honour students, post-doctoral fellows, and research associates. Their collective efforts are centred around pioneering bioengineering methodologies to tackle global challenges in regenerative medicine, health, and nutrition. This endeavour is fortified by collaborations with experts in various fields, such as data science, molecular dynamics, chemistry, physics, biology, clinical practice, and nutrition.
My research endeavours revolve around pioneering new materials, implantable devices, and compounds with the potential to treat and prevent a range of health conditions, including cardiovascular disease, viral infections, cancer, osteoporosis, and various other ailments. My primary focus lies in the innovation of biodegradable and elastic polymers, bioglasses, and hybrid materials that possess distinctive attributes for applications in medical devices and tissue regeneration. Additionally, I am dedicated to creating materials tailored for minimally invasive surgical procedures, aiming to overcome current challenges associated with injectable formulations, such as degradability, injectability, and mechanical strength. Successfully addressing these hurdles could substantially revolutionize the development of materials capable of addressing a multitude of health concerns, including heart failure for patients who suffer congenital heart diseases, burn, sports injuries and bone deficiencies.
My current investigations delve into the utilization of these groundbreaking biomaterial categories for both drug delivery and medical implants. Another facet of my research involves exploring the potential of naturally sourced compounds for the creation of nutritious food products or therapeutic applications capable of mitigating risks associated with diseases like cancer, cardiovascular disorders, and osteoporosis. I have also partnered with computational modelling experts to delve into virtual high throughput screening and in vitro experimentation, seeking out Senolytics—a classification of drugs known to counteract cellular senescence, a phenomenon linked to numerous chronic and age-related illnesses.
The following outlines a snapshot of my ongoing research objectives:
- Create bioinspired designs for heart valves by computational modelling and improving surface material properties to enhance their biocompatibility
- Devise inventive techniques for modifying surfaces to heighten the biocompatibility of medical instruments, particularly cardiovascular implants
- Engineer miniaturized biosensors for disease diagnosis and the monitoring of food safety and quality
- Formulate intelligent hydrogels tailored for precise drug delivery
- Craft hydrogels responsive to stimuli, allowing for non-invasive procedures and drug administration
- Identify potent compounds and their configurations for combatting viral infections, such as herpes simplex virus infection
- Undertake the biosynthesis of nutritional compounds, including fats
- Develop processes for extracting proteins from natural resources, with an eye towards future food innovation
- Innovate techniques for texturizing proteins to shape the landscape of nutritional food advancements.
CHNG5605- Bio-Products: Laboratory to Marketplace
CHNG5602-Biophysics and Biosensors
CHNG5022- Capstone Project B Extended
CHNG5222- Dissertation A
CHNG5223- Dissertation B
HDR Supervision:
Hsien-yin Kao Gene therapy for neurofibromatosis types 1 and 2
Andreas Hope Improving properties of plant-based protein for production of functional foods
Ziqi Li Improving functional properties of Australian Pulse concentrates
Cheng Wang Enhancing the mechanical properties of a biopolymer for biodmedical applications
Timothy Schofield Engineering a targeted delivery system
Wenxuan Zhang Improving toughness of elastic material for soft robotic and polymeric heart valve fabrication
Aylar Eslami Sustainable material for medical device fabrication
Available Scholarships:
Are you a highly motivated and ambitious researcher eager to make a real impact? Join our dynamic and multidisciplinary research team at the forefront of cutting-edge innovation! We are looking for outstanding PhD candidates to contribute to groundbreaking projects addressing major global challenges in healthcare, advanced materials, and biotechnology.
In our team, you will:
- Work on transformative research with real-world applications
- Collaborate with leading industry partners to translate discoveries into impactful solutions
- Be part of an entrepreneurial and innovative environment, surrounded by experts with a strong track record of research translation and commercialization
- Gain access to world-class facilities and work alongside an inspiring network of researchers across engineering, science, and medicine
If you are passionate about pushing the boundaries of knowledge and turning research into real-world solutions, we want to hear from you.
- Leadership Award women in STEM 2024
- University of Sydney Vice Chancellor Award for the Outstanding Research Engagement and Innovation in 2020
- University of Sydney Vice Chancellor Award for the Best Supervision in 2019
- UNSW Alumni Award of Excellence in Engineering in 2019
- Award of Excellence from Australia and New Zealand Federation of Chemical Engineers in 2017
- Selected as one of the top Engineers for innovation in 2016 by Engineers Australia
Project title | Research student |
---|---|
Improving the properties of a sustainable polymer for medical applications | Aylar ESLAMI SAED |
Improving textural and sensory properties of plant-based meat analogues | Andreas HOPF |
Gene Therapy for Neurofibromatosis types 1 and 2 | Hsien KAO |
Functional properties of Australian pulse concentrates and their enhancement for applications in protein-rich products | Ziqi LI |
Development of Biodegradable Nanofibrous Sensors for Biomedical Applications | Milad RAZBIN |
Engineering a Targeted Delivery System | Timothy SCHOFIELD |
Study the interface of polymer protein for a stable immobilization | Longfei YIN |
Publications
Book Chapters
- Wu, J., Blackshaw, K., Cho, J., Koolaji, N., Yun, J., Schindeler, A., Valtchev, P., Dehghani, F. (2021). Recovery of high-value compounds from food by-products. In Not known (Eds.), Food Engineering Innovations Across the Food Supply Chain, (pp. 61-88). TBC. [More Information]
- Dehghani, F., Fathi, A. (2017). Challenges for Cartilage Regeneration. In Qing Li, Yiu-Wing Mai (Eds.), Biomaterials for Implants and Scaffolds, (pp. 389-466). Berlin: Springer. [More Information]
- Dehghani, F., Fathi, A. (2016). Hydrogel Architecture. In Utkan Demirci, Ali Khademhosseini (Eds.), GELS HANDBOOK Fundamentals, Properties and Applications Volume 1: Fundamentals of Hydrogels, (pp. 81-129). Singapore: World Scientific Publishing Co. Pte. Ltd. [More Information]
Journals
- Rath, R., Herrington, J., Adeel, M., Guder, F., Dehghani, F., Farajikhah, S. (2024). Ammonia detection: A pathway towards potential point-of-care diagnostics. Biosensors and Bioelectronics, 251, 116100. [More Information]
- Rath, R., Naficy, S., Giaretta, J., Oveissi, F., Yun, J., Dehghani, F., Farajikhah, S. (2024). Chemiresistive Sensor for Enhanced CO2 Gas Monitoring. ACS Sensors, 9(4), 1735-1742. [More Information]
- Crago, M., Tan, R., Hung, J., Wise, S., Akhavan, B., Bilek, M., Dehghani, F., Talebian, S., Naficy, S. (2024). Durable plasma-mediated zwitterionic grafting on polymeric surfaces for implantable medical devices. Communications Materials, 5(1). [More Information]
Conferences
- Giaretta, J., Duan, H., Oveissi, F., Farajikhah, S., Dehghani, F., Naficy, S. (2021). Flexible enzymatic sensors for detection of hydrogen peroxide. 20th IEEE Sensors, SENSORS 2021, Piscataway: Institute of Electrical and Electronics Engineers (IEEE). [More Information]
- Bahramian, B., Ma, Y., Dehghani, F. (2015). Development of an antimicrobial and biodegradable polymer for food packaging applications. Annual Technical Conference - ANTEC, Conference Proceedings, : Springer Verlag.
Patents
- Fathi, A., Weiss, A., Dehghani, F., Mithieux, S. (2021). Application of Thermoresponsive Bioactive Injectable Hydrogel for Bone Regeneration. Patent No. 2016314146, 2016314146, 2016314146, 6851377, EP3344304, EP3344304, EP3344304. , .
- Fathi, A., Weiss, A., Dehghani, F., Wei, H., Mithieux, S. (2017). Design of a New Crosslinker for Biopolymer Hydrogel Fabrication. Patent No. 2794701, 2794701, 2794701, 9546235. , , , Czech Republic, Denmark, Finland, France, Germany, Norway, Spain, Sweden, Switzerland, Turkey, United Kingdom, Czech Republic, Denmark, Finland, France, Germany, Norway, Spain, Sweden, Switzerland, Turkey, United Kingdom, Czech Republic, Denmark, Finland, France, Germany, Norway, Spain, Sweden, Switzerland, Turkey, United Kingdom.
- Dehghani, F., Zhong, X. (2015). A Solvent Free Process for Synthesis of Catalysts in Manufacturing Biodegradable Polymers. Patent No. 9062155.
2024
- Rath, R., Herrington, J., Adeel, M., Guder, F., Dehghani, F., Farajikhah, S. (2024). Ammonia detection: A pathway towards potential point-of-care diagnostics. Biosensors and Bioelectronics, 251, 116100. [More Information]
- Rath, R., Naficy, S., Giaretta, J., Oveissi, F., Yun, J., Dehghani, F., Farajikhah, S. (2024). Chemiresistive Sensor for Enhanced CO2 Gas Monitoring. ACS Sensors, 9(4), 1735-1742. [More Information]
- Crago, M., Tan, R., Hung, J., Wise, S., Akhavan, B., Bilek, M., Dehghani, F., Talebian, S., Naficy, S. (2024). Durable plasma-mediated zwitterionic grafting on polymeric surfaces for implantable medical devices. Communications Materials, 5(1). [More Information]
2023
- Shahrbabaki, Z., Farajikhah, S., Ghasemian, M., Oveissi, F., Rath, R., Yun, J., Dehghani, F., Naficy, S. (2023). A Flexible and Polymer-Based Chemiresistive CO2 Gas Sensor at Room Temperature. Advanced Materials Technologies, 8(10), 2201510. [More Information]
- Rath, R., Oveissi, F., Shahrbabaki, Z., Yun, J., Naficy, S., Dehghani, F., Farajikhah, S. (2023). A paper-based sensor capable of differentiating ammonia and carbon dioxide gas. Materials Today Communications, 35. [More Information]
- Talebian, S., Mendes, B., Conniot, J., Farajikhah, S., Dehghani, F., Li, Z., Bitoque, D., Silva, G., Naficy, S., Conde, J., et al (2023). Biopolymeric Coatings for Local Release of Therapeutics from Biomedical Implants. Advanced Science. [More Information]
2022
- Cheng, H., Oveissi, F., Daly, S., Shahrbabaki, Z., Naficy, S., Dehghani, F. (2022). A green and biodegradable plasticizer from copolymers of poly(β-hydroxybutyrate-co-ε-caprolactone). Journal of Applied Polymer Science, 139(22). [More Information]
- Giaretta, J., Duan, H., Farajikhah, S., Oveissi, F., Dehghani, F., Naficy, S. (2022). A highly flexible, physically stable, and selective hydrogel-based hydrogen peroxide sensor. Sensors and Actuators B: Chemical, 371. [More Information]
- Talebian, S., schofield, T., Valtchev, P., Schindeler, A., Kavanagh, J., Adil, Q., Dehghani, F. (2022). Biopolymer-Based Multilayer Microparticles for Probiotic Delivery to Colon. Advanced Healthcare Materials, 11(11). [More Information]
2021
- Fathi, A., Weiss, A., Dehghani, F., Mithieux, S. (2021). Application of Thermoresponsive Bioactive Injectable Hydrogel for Bone Regeneration. Patent No. 2016314146, 2016314146, 2016314146, 6851377, EP3344304, EP3344304, EP3344304. , .
- Fois, C., Schindeler, A., Valtchev, P., Dehghani, F. (2021). Dynamic flow and shear stress as key parameters for intestinal cells morphology and polarization in an organ-on-a-chip model. Biomedical Microdevices, 23(4), 55. [More Information]
- Molina Ortiz, J., McClure, D., Shanahan, E., Dehghani, F., Holmes, A., Read, M. (2021). Enabling rational gut microbiome manipulations by understanding gut ecology through experimentally-evidenced in silico models. Gut Microbes, 13(1), 1965698. [More Information]
2020
- Koolaji, N., Shammugasamy, B., Schindeler, A., Dong, Q., Dehghani, F., Valtchev, P. (2020). Citrus Peel Flavonoids as Potential Cancer Prevention Agents. Current Developments in Nutrition, 4(5), 1-20. [More Information]
- Naficy, S., Dehghani, F., Chew, Y., Hawthorne, W., Le, T. (2020). Engineering a Porous Hydrogel-Based Device for Cell Transplantation. ACS Applied Bio Materials, 3(4), 1986-1994. [More Information]
- Ebrahimi, P., Youssef, D., Salve, G., Ayer, J., Dehghani, F., Fletcher, D., Winlaw, D. (2020). Evaluation of personalized right ventricle to pulmonary artery conduits using in silico design and computational analysis of flow. JTCVS Open, 1(C), 33-48. [More Information]
2019
- Hassan, M., Dave, K., Chandrawati, R., Dehghani, F., Gomes, V. (2019). 3D printing of biopolymer nanocomposites for tissue engineering: Nanomaterials, processing and structure-function relation. European Polymer Journal, 121, 1-15. [More Information]
- Arab, M., Bahramian, B., Schindeler, A., Fathi, A., Valtchev, P., McConchie, R., Dehghani, F. (2019). A benign process for the recovery of solanesol from tomato leaf waste. Heliyon, 5(4), 1-17. [More Information]
- Cheng, T., Leblanc, E., Kalinina, A., Cantrill, L., Valtchev, P., Dehghani, F., Little, D., Schindeler, A. (2019). A Bioactive Coating Enhances Bone Allografts in Rat Models of Bone Formation and Critical Defect Repair. Journal of Orthopaedic Research, 37(11), 2278-2286. [More Information]
2018
- Daly, S., Fathi, A., Bahramian, B., Manavi Tehrani, I., McClure, D., Valtchev, P., Schindeler, A., Dehghani, F., Kavanagh, J. (2018). A green process for the purification of biodegradable poly(B-hydroxybutyrate). The Journal of Supercritical Fluids, 135, 84-90. [More Information]
- Torabian, G., Bahramian, B., Zambon, A., Spilimbergo, S., Adil, Q., Schindeler, A., Valtchev, P., Dehghani, F. (2018). A hybrid process for increasing the shelf life of elderberry juice. The Journal of Supercritical Fluids, 140, 406-414. [More Information]
- Sangian, D., Naficy, S., Dehghani, F., Yamauchi, Y. (2018). A Review on Layered Mineral Nanosheets Intercalated with Hydrophobic/Hydrophilic Polymers and Their Applications. Macromolecular Chemistry and Physics, 219(13), 1-14. [More Information]
2017
- Fathi, A., Weiss, A., Dehghani, F., Wei, H., Mithieux, S. (2017). Design of a New Crosslinker for Biopolymer Hydrogel Fabrication. Patent No. 2794701, 2794701, 2794701, 9546235. , , , Czech Republic, Denmark, Finland, France, Germany, Norway, Spain, Sweden, Switzerland, Turkey, United Kingdom, Czech Republic, Denmark, Finland, France, Germany, Norway, Spain, Sweden, Switzerland, Turkey, United Kingdom, Czech Republic, Denmark, Finland, France, Germany, Norway, Spain, Sweden, Switzerland, Turkey, United Kingdom.
- Dehghani, F., Fathi, A. (2017). Challenges for Cartilage Regeneration. In Qing Li, Yiu-Wing Mai (Eds.), Biomaterials for Implants and Scaffolds, (pp. 389-466). Berlin: Springer. [More Information]
- Manavi Tehrani, I., Fathi, A., Wang, Y., Maitz, P., Mirmohseni, F., Cheng, T., Peacock, L., Little, D., Schindeler, A., Dehghani, F. (2017). Fabrication of a Biodegradable Implant with Tunable Characteristics for Bone Implant Applications. Biomacromolecules, 18(6), 1736-1746. [More Information]
2016
- Bahramian, B., Ma, Y., Rohanizadeh, R., Chrzanowski, W., Dehghani, F. (2016). A new solution for removing metal-based catalyst residues from a biodegradable polymer. Green Chemistry, 18(13), 3740-3748. [More Information]
- Negahi Shirazi, A., Fathi, A., Suarez, F., Wang, Y., Maitz, P., Dehghani, F. (2016). A Novel Strategy for Softening Gelatin-Bioactive-Glass Hybrids. ACS Applied Materials and Interfaces, 8(3), 1676-1686. [More Information]
- Bahramian, B., Fathi, A., Dehghani, F. (2016). A renewable and compostable polymer for reducing consumption of non-degradable plastics. Polymer Degradation and Stability, 133, 174-181. [More Information]
2015
- Paini, M., Daly, S., Aliakbarian, B., Fathi, A., Arab-Tehrany, E., Perego, P., Dehghani, F., Valtchev, P. (2015). An efficient liposome based method for antioxidants encapsulation. Colloids And Surfaces B: Biointerfaces, 136, 1067-1072. [More Information]
- Negahi Shirazi, A., Chrzanowski, W., Khademhosseini, A., Dehghani, F. (2015). Anterior cruciate ligament: Structure, injuries and regenerative treatments. In Luiz E. Bertassoni, Paulo G. Coelho (Eds.), Engineering Mineralized and Load Bearing Tissues, (pp. 161-186). Cham: Springer. [More Information]
- Ravarian, R., Murphy, C., Schindeler, A., Rawal, A., Hook, J., Dehghani, F. (2015). Bioactive poly(methyl methacrylate) for bone fixation. RSC Advances, 5(75), 60681-60690. [More Information]
2014
- Lee, S., Zhong, X., Ravarian, R., Valtchev, P., Dehghani, F. (2014). An Approach to Improve the Efficiency of Polymerization and Enhance Biological Activity of Poly(lactide-co-ethylene oxide fumarate) Hydrogels. Journal of Polymer Science, Part A: Polymer Chemistry, 52(9), 1291-1299. [More Information]
- Berenjian, A., Mahanama, R., Talbot, A., Regtop, H., Kavanagh, J., Dehghani, F. (2014). Designing of an Intensification Process for Biosynthesis and Recovery of Menaquinone-7. Applied Biochemistry and Biotechnology, 172(3), 1347-1357. [More Information]
- Wong, J., Kwok, P., Noakes, T., Fathi, A., Dehghani, F., Chan, H. (2014). Effect of crystallinity on electrostatic charging in dry powder inhaler formulations. Pharmaceutical Research, 31(7), 1656-1664. [More Information]
2013
- Cheng, T., Valtchev, P., Murphy, C., Cantrill, L., Dehghani, F., Little, D., Schindeler, A. (2013). A sugar-based phase-transitioning delivery system for bone tissue-engineering. European Cells and Materials, 26, 208-221. [More Information]
- Berenjian, A., Chan, N., Mahanama, R., Talbot, A., Regtop, H., Kavanagh, J., Dehghani, F. (2013). Effect of Biofilm Formation by Bacillus subtilis natto on Menaquinone-7 Biosynthesis. Molecular Biotechnology, 54(2), 371-378. [More Information]
- Vrana, N., Lavalle, P., Dokmeci, M., Dehghani, F., Ghaemmaghami, A., Khademhosseini, A. (2013). Engineering Functional Epithelium for Regenerative Medicine and In Vitro Organ Models: A Review. Tissue Engineering. Part B. Reviews, 19(6), 529-543. [More Information]
2012
- Berenjian, A., Mahanama, R., Talbot, A., Regtop, H., Kavanagh, J., Dehghani, F. (2012). Advances in menaquinone-7 production by bacillus subtilis natto: Fed-batch glycerol addition. American Journal of Biochemistry and Biotechnology, 8(2), 105-110. [More Information]
- Chrzanowski, W., Yeow, W., Rohanizadeh, R., Dehghani, F. (2012). Bone bonding ability-how to measure it? RSC Advances, 2(24), 9214-9223. [More Information]
- Ostrovidov, S., Annabi, N., Seidi, A., Ramalingam, M., Dehghani, F., Kaji, H., Khademhosseini, A. (2012). Controlled Release of Drugs from Gradient Hydrogels for High-Throughput Analysis of Cell-Drug Interactions. Analytical Chemistry, 84(3), 1302-1309. [More Information]
2011
- Wei, H., Ravarian, R., Dehn, S., Perrier, S., Dehghani, F. (2011). Construction of temperature responsive hybrid crosslinked self-assemblies based on PEG-b-P(MMA-co-MPMA)-b-PNIPAAm triblock copolymer: ATRP synthesis and thermoinduced association behavior. Journal of Polymer Science, Part A: Polymer Chemistry, 49(8), 1809-1820. [More Information]
- Berenjian, A., Mahanama, R., Talbot, A., Biffin, R., Regtop, H., Valtchev, P., Kavanagh, J., Dehghani, F. (2011). Efficient media for high menaquinone-7 production: Response surface methodology approach. New Biotechnology, 28(6), 665-672. [More Information]
- Dehghani, F., Annabi, N. (2011). Engineering Porous Scaffolds Using Gas-Based Techniques. Current Opinion in Biotechnology, 22(5), 661-666. [More Information]
2010
- Syed Muhammad, S., Langrish, T., Tang, P., Adi, H., Chan, H., Kazarian, S., Dehghani, F. (2010). A novel method for the production of crystalline micronised particles. International Journal of Pharmaceutics, 388(1-2), 114-122. [More Information]
- Annabi, N., Nichol, J., Zhong, X., Ji, C., Koshy, S., Khademhosseini, A., Dehghani, F. (2010). Controlling the Porosity and Microarchitecture of Hydrogels for Tissue Engineering. Tissue Engineering. Part B. Reviews, 16(4), 371-383. [More Information]
- Annabi, N., Mithieux, S., Weiss, A., Dehghani, F. (2010). Cross-linked open-pore elastic hydrogels based on tropoelastin, elastin and high pressure CO(2). Biomaterials, 31(7), 1655-1665. [More Information]
2009
- Dehghani, F., Annabi, N., Titus, M., Valtchev, P., Tumilar, A. (2009). Sterilization of Ginseng Using a High Pressure CO 2 at Moderate Temperatures. Biotechnology and Bioengineering, 102(2), 569-576. [More Information]
- Annabi, N., Mithieux, S., Boughton, E., Ruys, A., Weiss, A., Dehghani, F. (2009). Synthesis of highly porous crosslinked elastin hydrogels and their interaction with fibroblasts in vitro. Biomaterials, 30(27), 4550-4557. [More Information]
- Dehghani, F., Meure, L., Knott, R., Foster, N. (2009). The depressurisation of an expanded solution into aqueous media for the bulk production of liposomes. Langmuir, 25(1), 326-337. [More Information]
2008
- Meure, L., Foster, N., Dehghani, F. (2008). Conventional and dense gas techniques for the production of liposomes: a review. AAPS PharmSciTech, 9(3), 798-809. [More Information]
- Dehghani, F., Annabi, N., Valtchev, P., Mithieux, S., Weiss, A., Kazarian, S., Tay, F. (2008). Effect of dense gas CO2 on the coacervation of elastin. Biomacromolecules, 9(4), 1100-1105. [More Information]
- Barrett, A., Dehghani, F., Foster, N. (2008). Increasing the dissolution rate of itraconazole processed by gas antisolvent techniques using polyethylene glycol as carrier. Pharmaceutical Research, 25(6), 1274-1289. [More Information]
2007
- Tandya, A., Mammucari, R., Dehghani, F., Foster, N. (2007). Dense gas processing of polymeric controlled release formulations. International Journal of Pharmaceutics, 328, 1-11. [More Information]
- Sih, R., Dehghani, F., Foster, N. (2007). Viscosity measurements on gas expanded liquid systems - Methanol and carbon dioxide. The Journal of Supercritical Fluids, 41(1), 148-157. [More Information]
2006
- Mammucari, R., Dehghani, F., Foster, N. (2006). Dense Gas Processing of Micron-Sized Drug Formulations Incorporating Hydroxypropylated and Methylated Beta-Cyclodextrin. Pharmaceutical Research, 23(2), 429-437. [More Information]
- Combes, G., Coen, E., Dehghani, F., Foster, N. (2006). Kinetic Study of the Hydrogenation of 2-(6-Methoxy-2-naphthyl)propenoic Acid to (S)-Naproxen with Ruthenium BINAP Catalyst in Methanol. Industrial and Engineering Chemistry Research, 45(4), 1281-1290. [More Information]
- Tandya, A., Dehghani, F., Foster, N. (2006). Micronization of cyclosporine using dense gas techniques. The Journal of Supercritical Fluids, 37(3), 272-278. [More Information]
2005
- Combes, G., Coen, E., Dehghani, F., Foster, N. (2005). Dense CO2 expanded methanol solvent system for synthesis of naproxen via enantioselective hydrogenation. The Journal of Supercritical Fluids, 36(2), 127-136. [More Information]
- Combes, G., Dehghani, F., Mammucari, R., Foster, N. (2005). Hydrogenation reactions in dense gas systems. In Lee, S. and LaPierre, C. W (Eds.), Encyclopedia of Chemical Processing, (pp. 1337-1348). United States: Marcel Dekker.
- Mammucari, R., Dehghani, F., Foster, N. (2005). Processing pharmaceuticals using dense gas technologies. In Lee, S. and LaPierre, C. W (Eds.), Encyclopedia of Chemical Processing, (pp. 2451-2459). United States: Marcel Dekker.
2004
- Meure, L., Warwick, B., Dehghani, F., Regtop, H., Foster, N. (2004). Increasing copper indomethacin solubility by co-precipitation with polyvinylpyrrolidone using the aerosol solvent extraction system. Industrial and Engineering Chemistry Research, 43(4), 1103-1112.
- Bezanehtak, K., Dehghani, F., Foster, N. (2004). Vapour-liquid equilibrium for the carbon dioxide+hydrogen+methanol ternary system. Journal of Chemical and Engineering Data, 49(3), 430-434. [More Information]
2003
- Foster, N., Dehghani, F., Charoenchaitrakool, K., Warwick, B. (2003). Application of dense gas techniques for the production of fine particles. AAPS PharmSciTech, 5(2, Article 11), 1-7.
- Dehghani, F., Foster, N. (2003). Dense gas anti-solvent processes for pharmaceutical formulation. Current Opinion in Solid State and Materials Science, 7(4-5), 363-369. [More Information]
- Spilimbergo, S., Dehghani, F., Bertucco, A., Foster, N. (2003). Inactivation of bacteria and spores by pulsed electric field and high pressure CO2 at low temperature. Biotechnology and Bioengineering, 82(1), 118-125. [More Information]
2002
- Stanton, L., Dehghani, F., Foster, N. (2002). Improving drug delivery using polymers and supercritical fluid technology. Australian Journal of Chemistry, 55(6-7), 443-447. [More Information]
- Sze Tu, L., Dehghani, F., Foster, N. (2002). Micronisation and microencapsulation of pharmaceuticals using a carbon dioxide antisolvent. Powder Technology, 126(2), 134-149.
- Warwick, B., Dehghani, F., Foster, N., Biffin, J., Regtop, H. (2002). Micronisation of copper-indomethacin using gas anti-solvent processes. Industrial and Engineering Chemistry Research, 41(8), 1993-2004.
Selected Grants
2025
- Elastic Biopolymer for Designing Surgical Sutures, Dehghani F, Bilek M, Talebian S, Naficy S, Farajikhah S, Ling W, Australian Research Council (ARC)/Linkage Projects (LP)
2024
- Portable biosensor for rapid detection of viral contamination in food, Dehghani F, Farajikhah S, Naficy S, Talebian S, Australian Research Council (ARC)/Linkage Projects (LP)
- Automated Robotic System for Seamless Manufacturing of Polymeric Heart Valve Replacements with EnhancedLongevity and Possibility for Personalisation, Naficy S, Dehghani F, Talebian S, Lee A, Department of Education and Training (Federal)/Australias Economic Accelerator Seed Program
Bioengineering Laboratory Research Team:
- A/Professor Sina Naficy (Team director for polymeric heart valve)
- Dr Peter Valtchev (Senior research fellow, Team leader for future protein & drug discovery)
- Dr Syamak Farajikhah (Research fellow, Team leader for biosensor design)
- Dr Sepehr Talebian (Research fellow, Team leader for smart drug delivery system)
- Dr Jiadai Wu (Research fellow)
- Dr Valeria Messina (Research fellow)
- Dr Aeryne Lee (Research fellow)
- Dr Jacopo Giaretta (Research fellow)
- Dr Xinying Liu (Research Associate)
- Dr Hoang Yen Vo
Bioengineering Laboratory Facility
Our research team hosts or has access to world-class facilities for the synthesis and characterisation of biomaterials, sensor design, and recovery of active compounds for natural resources as well as full PC2 (biological) labs for cell culture, bacteria and similar. More advanced facilities are also available through platforms such as Engineering Analytical facility, USyd Advanced Mircoscopy Facility and theUSyd Nano research Institute.
The followings are list of some of these facilities
Processing
- 3D-printers: 3D Bioplotter® (Envision TEC, Manufacturing Series), 4-axis robotic printer (Nordson), inkjet printer (Dimatix FujiFilm)
- Twin-screw extruder micro-compounder (Xplore 15),
- fluidised bed dryer (Mini Glat),
- Atlas fully automated stirred reactor with controlled temperature,
- Freeze dryer,
- Rotary evaporator
- Bioreactors with a controller system,
- plasma chamber
- advanced micronisation and microencapsulation equipment
- CDC Biofilm Reactor® (BIOSURFACE TECHNOLOGIES CORPORATION)
- Cell culturing facility (e.g. incubators, laminar flow cabinets (class 1 and 2), autoclave, UV spectrometer, centrifuge, cell counter, etc)
- Potentiostat/Galvanostat/ZRA (CHI660E, ZIVE SP1)
- EDAQ (Dual Picostat, E-corder)
- Gas Mixing setup
- DropSens portable Potentiostat
Analytical
- Heart valve pulse duplicator,
- flow cytometry,
- fluorescence microscopy and optical microscopy,
- Mechanical testing (biaxial (TA-Bose) and Uniaxial (Instron Biophysics®),
- HPLC-mass spectrometry,
- HPLC with UV, RI and ELSD detectors
- Electrophoresis and western blot
- Micro-plate reader,
- Permeability testing,
- Solid State zeta potential (SurPASS 3), an analytical instrument that enables measuring zeta potential of materials with different geometries and in situ reporting of environmental conditions (e.g. pH, temperature, material conductivity),
- Water activity testing
Bioengineering Laboratory Alumni
- Ronil Rat (PhD, USyd graduate)
- Zhongyan Li (Mphil, Usyd graduate)
- Juan Molina Ortiz (PhD, USyd graduate)
- Jacopo Giaretta (PhD, USyd graduate)
- Zahra Karbalaei (PhD, USyd graduate)
- Xinying Liu (PhD, USyd graduate)
- Aeryne Lee (PhD, USyd graduate)
- Diana Bogueva (Centre manager, Postdoctoral, USyd)
- Katherine Blackshaw (PhD, USyd graduate)
- Chiara Fois (PhD, USyd graduate)
- Long Nguyen (PhD, USyd graduate)
- Farshad Oveissi (PhD, USyd graduate)
- Nooshin Koolaji (Postdoctoral fellow, USyd)
- Balakrishnan Shammugasamy (PhD, USyd graduate)
- Yanwei Ma (PhD, USyd graduate)
- Sean Daly (PhD, USyd graduate)
- Farid Mirmohseni (PhD, USyd graduate)
- Sahar Biglari (PhD, USyd graduate)
- Jiadai Wu (Daisy) (PhD, USyd graduate)
- Reza M Behi (PhD, USyd graduate)
- Marjan Arab (PhD, USyd graduate)
- Thomas Tarento (PhD, USyd graduate)
- Golnoosh Torabian (PhD, USyd graduate)
- Iman ManaviTehrani (PhD, USyd graduate)
- Bahareh Bahramian (PhD, USyd graduate)
- Ali Fathi ((PhD, USyd graduate)
- Negar Talaie Zanjani (PhD, USyd graduate)
- Ali Negahi Shirazi (PhD, USyd graduate)
- Bahar Aliakbarian (Visiting Fellow, Genoa U)
- Tegan Cheng (PhD, USyd graduate)
- Roya Ravarian (PhD, USyd graduate)
- Hua Wei (Postdoctoral Fellow from Wuhan University)
- Gavin Marshal (PhD, USyd graduate)
- Aydin Berenjian (PhD, USyd graduate)
- Rajah Mahanama (PhD, USyd graduate)
- Mohd Fareed Mohd Sairi (PhD, USyd graduate)
- Sherry Lee (PhD, USyd graduate)
- Peter Valtchev (PhD, USyd graduate)
- Syed AF Syed Muhammad (PhD, USyd graduate)
- Chengdong Ji (PhD, USyd graduate)
- Rachel (Xia) Zhong (PhD, USyd graduate)
- Nasim Annabi (PhD, USyd graduate)
- Jeff Eliss (PhD, Visiting fellow, Ohio State U)
- Nan Xie (Mphil, USyd Graduate)
- Rodrick Shi (PhD, UNSW graduate)
- Aaron Ng (PhD, UNSW graduate)
- Aldrich Tandya (PhD, UNSW graduate)
- Angela Barret (PhD, UNSW graduate)
- Louise Meure (PhD, UNSW graduate)
- Raffaella Mammucari (PhD, UNSW graduate)
- Keivan Bezenahtak (PhD, UNSW graduate)
- Kiang Manop Charoenchaitrakool (PhD, UNSW graduate)
- Linda Ze Tu (PhD, UNSW graduate)
- Gary Combes (PhD, UNSW graduate)
- Russel Thiering (PhD, UNSW graduate)
- Barry Warwick (PhD, UNSW graduate)
- Rana Bustami (PhD, USyd graduate)