Professor Hala Zreiqat

Bsc (Hons) Jordan PhD UNSW
NHMRC Senior Research Fellow
Head: Biomaterials & Tissue Engineering Research Unit
Founder & Chair of ADATE
Member of Bosch Institute
Visiting Professor at American University of Beirut (AUB)
Professor AMME

J07 - Mechanical Engineering Building
The University of Sydney

Telephone +61 2 9351 2392
Fax +61 2 9351 7060

Website ADATE - Alliance for Design and Application in Tissue Engineering

Bosch Institute

Biomaterials and Tissue Engineering Research Unit

Curriculum vitae Curriculum vitae

Biographical details

Hala Zreiqat is Professor of Biomedical Engineering, a 2016-2017 Radcliff-Harvard Fellow, a National Health and Medical Research Council Senior Research Fellow, and is Head of the Biomaterials and Tissue Engineering Research Unit in the Faculty of Engineering at the University of Sydney. Her group consists of multidisciplinary team of researchers including engineers, cell and molecular biologists and clinicians. Her lab works on the development of novel engineered materials and 3D printed platforms for regenerative medicine, particularly in the fields of orthopaedics, dental and maxillofacial applications. In addition, her group is interested in the development of novel nanospheres for growth factors, drug and cell delivery as well as novel injectable materials. She has over 100 peer-reviewed publications. Her pioneering development of innovative biomaterials for tissue regeneration has led to one awarded (US) and 6 provisional patents, 5 as a lead inventor, and several collaborations with inter/national industry partners. She is regularly invited to give keynote and plenary presentations at major international and national conferences. She has organized / chaired a number of major international conferences/ symposia / workshops. She is the immediate past president of the Australian and New Zealand Orthopaedic research Society (2010-2012). She is the founder and chair of the Alliance for Design and Application in Tissue Engineering. Amongst her awards are: Leopold Dintenfass Memorial Award, for Excellence in Research (2012); University of Sydney Engineering Deans Research Award (2009).

Research interests

Millions of people worldwide suffer bone loss due to injury, infection, disease or abnormal skeletal development, and treatment frequently requires regeneration of new bone. Since each patient has only a limited amount of bone available for grafting, the demand for synthetic bone substitutes is high. Those currently available are far from optimal, but Professor Hala Zreiqat has developed a unique ceramic material that acts as a scaffold on which the body can regenerate new bone, then gradually degrades as it is replaced by natural bone.

"The bone substitute my team and I have developed resembles natural bone in terms of architecture, strength and porosity. So it is strong enough to withstand the loads that will be applied to it, and also contains pores that allow blood and nutrients to penetrate it. In this way it is designed to encourage normal bone growth, and to eventually be replaced by natural bone in the body.

"The fact that it actually 'kick starts' the process of bone regeneration makes it far superior to other available materials. Our tests also show that it will not be rejected by the body. In addition, we can make as many implants as we want from this material, so availability will not be a problem.

"This material has the potential to positively affect the quality of life of millions of people globally, so we are hoping to see it in use clinically within the next 10 years.

Teaching and supervision

AMME4971 - Tissue Engineering

AMME5971 - Applied Tissue Engineering

Current research students

Project title Research student
Development of biomaterials for musculoskeletal regeneration Leon JIANG
Development and characterization of injectable doped calcium silicate composite materials Young NO
Clinical and Laboratory Research in Osseointegration Seamus THOMSON
Using Novel Methods to coat Orthopaedic Implants with a Ceramic Material Christina VIRAY
Development of an elastomeric patch for cardiac repair: the effect of scaffold architecture and growth factor supplementation on bioactivity and attachment Steph YEE

Associations

  • President, Australian and New Zealand Orthopaedic Research Society (ANZORS) (2010-2012)
  • Secretary, Australian and New Zealand Orthopaedic Research Society (ANZORS) (2007-2009)
  • Member, Editorial Board, International Journal of Biomaterials Research and Engineering
  • Member, Editorial Board, Recent Patents on Biomedical Engineering
  • Associate Editor, Journal of Biomimetics, Biomaterials, and Tissue Engineering
  • Editorial Board, Journal of Medical Engineering

Awards and honours

Australian

  • 2016-2107 Radcliff Harvard Fellow
  • NHMRC Senior Research Fellowship AUD 622,655 (2016-2020)
  • John and Eileen Haddon Memorial Plaque from the Rebecca L Cooper Medical Research Foundation (2015)
  • Australia-Harvard Fellowship: AUD 10,000 (2013)
  • Leopold Dintenfass Memorial Award, for Excellence in Research (2012)
  • NHMRC Senior Research Fellowship: AUD 570,640 (2011-2015)
  • University of Sydney Engineering Deans Research Award (2009)
  • Australian Academy of Science Award for research undertaken at Laboratoire de Physiopathologie et Pharmacologie Articulaires, Faculté de Médicine, Université Henri Poincaré, France: AUD 10,500 (2009)
  • R Douglas Wright Biomedical Career Development Award (NHMRC): AUD 426,250 (2006-2010) Australian Academy of Science Award for research undertaken at Institute of Pathology, Johannes Gutenberg University, Mainz, Germany: AUD 11,000 (2004)
  • Australian Postgraduate Research Award (PhD scholarship): AUD 28,000 p.a. (1995-1997)

International

  • Advisor World Orthopaedic Alliance (WOA)- (October 2012-present)
  • German Academic Exchange Service (DAAD) award for research undertaken at Saarland University, Germany: AUD 10,000 (2011)
  • Invited Guest Professorship, Laboratoire de biomatériaux et polymères de spécialité, Institut Galilée, Université Paris 13: AUD 8,000 (2011)
  • Invited Guest Professorship, Laboratoire de biomatériaux et polymères de spécialité, Institut Galilée, Université Paris 13: AUD 8,000 (2007)
  • Invited Guest Professorship, Laboratoire de biomatériaux et polymères de spécialité, Institut Galilée, Université Paris 13: AUD 8,000 (2006)

National Collaboration

  • Dr James Chong (Millennium Institute) PhD, FRACP, MBBS, Senior Lecturer Medicine, Westmead Clinical School, The Westmead Institute for Medical Research
  • Associate Professor Geraldine O'Neil (Westmead Hospital): Paediatrics & Child Health, Children's Hospital, Westmead
  • Professor Chris Little: Director Raymond Purves Bone and Joint Research Labs Surgery, Northern Clinical School, Kolling Institute of Medical Research
  • Dr Tara Speranza: Senior Lecturer, Physiology, School of Medical Sciences
  • Associate Professor Axel Spahr, Dr. Med. Dent. Habil., MRACDS(Perio) Head - Department of Periodontics, Sydney Dental Hospital, Head - Discipline of Periodontics, University of Sydney
  • Dr Payal Mukherjee, MBBS, FRACS (ORLHNS), MS (Usyd) Clinical Senior Lecturer Surgery, Central Clinical School, Sydney Adventist Hospital Clinical School
  • Dr Roland Steck Sc Techn (ETH Zurich), Deputy Director, Medical Engineering Research Facility (MERF), Institute of Health and Biomedical Innovation (IHBI), Queensland University of Technology
  • Associate Professor Andrew Minett: Co-Director of the Laboratory for Sustainable Technology
  • Associate Professor Cynthia Whitchurch, ithree institute, the University of Technology, Sydney

In the media

    Visiting international academics

    • Dr Martin Vielreicher, Friedrich-Alexander-University Erlangen-Nuremberg, Germany (October 2015)
    • Professor Oliver Friedrich, Friedrich-Alexander-University Erlangen-Nuremberg, Germany, (September 2015)
    • Professor Sarah Heilshorn, Stanford University, University of Sydney's International Research Collaboration Award (January 2016)
    • Dr Yirong Chen, Orthopaedic and Trauma Surgeon, Nanfang Hospital, Southern Medical University, Guangzhou, China (January 2015-January 2016)
    • Assistant Professor Tolou Shokuhfar, Michigan Technological University, USA (April-May 2014)
    • Associate Professor Xiaobing Zhao, Changzhou University, China (2012-2013)
    • Professor Vicki Rosen, Harvard University - sponsored by an Australia-Harvard Fellowship (2012, 2013)
    • Professor Jeremy Mao, Columbia University, USA - sponsored by a University of Sydney International Visiting Fellowship (2008, 2009)

    Honorary appointments

    • Honorary Professor - Shanghai JiaoTong University,Faculty of Medicine, China (2013-2018)
    • Honorary Professor - Faculty of Medicince, University of Shanghai
    • Visiting Professor - American University of Beirut, Lebanon (2013)
    • Visiting Academic - School of Biomedical Engineering, Drexel University, USA (2010-continued)

    International links

    China

    (Jiao Tong University) Professor Xinquan Jiang, Oral Bioengineering Lab, Shanghai Research Institute of Stomatology.

    Germany

    (University of Erlangen-Nuremberg) Professor Oliver Friedrich, The Institute of Medical Biotechnology

    New Zealand

    (University of Otago, Christchurch) Associate Professor Tim Woodfield

    United States

    (Columbia University) Gordana Vunjak-Novakovic, Mikati Foundation Professor of Biomedical Engineering and Medical Sciences

    United States

    (Harvard University) Professor Professor Vicki Rosen, Department Head and Professor of Developmental Biology

    United States

    (Stanford University) Professor Sarah Heilshorn, Department of Materials Science & Engineering

    United States

    (Tufts University) Professor David Kaplan

    Selected grants

    2016

    • Novel 3D printed scaffolds for intervertebral fusion; Zreiqat H; Rebecca Cooper Foundation/Research Grant.
    • Collaborative Design of Materials for Bone Regeneration and Development of Biomedical Entrepreneurs Training Program; Heilshorn S, Zreiqat H; DVC Research/International Research Collaboration Award (IRCA).
    • Real time bio-impedance measurement of biological samples: Electrical Cell-substrate Impedance Spectroscopy ECIS Zθ equipped with Ibidi Pump System; Traini D, Young P, Zreiqat H, Grau G, Ammit A; National Health and Medical Research Council (NHMRC)/Equipment Grants.
    • Tissue Engineering approach to Musculoskeletal regeneration; Zreiqat H; National Health and Medical Research Council (NHMRC)/Career Awards: Research Fellowships.
    • 3D Printed Scaffolds for Bone Regeneration; Zreiqat H; DVC Research/Bridging Support Grant.

    2015

    • Using 3D printing technology to regenerate human bone; Zreiqat H; Rebecca L Cooper Medical Research Foundation/Equipment Grant.
    • Using 3D printing technology to develop architecturally-controlled synthetic bone substitutes; Zreiqat H, Li Q, Lee J; Australian Research Council (ARC)/Linkage Projects (LP).
    • The Cellular-Scaffold Interface unravelled: Advanced Multiphoton-Imaging to optimize Bone Tissue Engineering using novel mechanically strong, tough and bioactive 3 D printed Ceramics Biomaterialsscaffolds; Zreiqat H, Roohaniesfahani S, Friedrich O; Group of Eight/Germany Joint Research Co-operation Scheme.
    • Harnessing Mesenchymal Stem cell therapeutics for Bone Regeneration by Tumour Necrosis Factor-alpha; Lu Z, Zreiqat H; Perpetual Trustees Charitable Trusts/Research Support.
    • The SurPASS Electrokinetic Surface Potential Analyser for Solid Samples; Dunstan C, Jabbarzadeh-Khoei A, Neto C, Zreiqat H, Murray M; DVC Research/Equipment Grant.

    2014

    • Architecturally-controlled synthetic bone substitutes for bone regeneration under load; Roohaniesfahani S, Zreiqat H, Steck R, Han L; AO Foundation/Start-up Grants.
    • CLARIOstar Multifunctional Microplate Reader for Shared Used at the Open Access, Multi-User Molecular Biology Core Facility; Huang M, Scolyer R, Fraser S, Sahni S, Speranza T, Owens T, Barrs V, Ju Y, Kovacevic Z, Lu Z, Camp A, Slobedman B, Morris B, Oliver B, Dos Remedios C, Kalinowski D, Fu D, Lai D, Lovicu F, Allbutt H, Triccas J, Burgess J, Kril J, Dixon K, Rendina L, Byrne M, King N, Groundwater P, Williamson P, Ho J, Dong Q, Bao B, Assinder S, McLennan S, Richardson D, Ammit A, Sharland A, Hardikar A, Hong A, Hambly B, Lee C, Murphy C, Goldsbury C, Johnstone D, Lane D, Hibbs D, Joshua D, Huq F, Halliday G, Sutherland G, Zreiqat H, Lok H, Lyons G, Jansson P, Black J, Zhu L, Sunde M, Day M, Naylor M, Buckland M, Murray M, Shafie N, Lay P, Poronnik P, Codd R, Mason R, Ryan R, Christopherson R, de Graaf S; National Health and Medical Research Council (NHMRC)/Equipment Grants.
    • Engineering strategies for bone regeneration through microstructural design; Zreiqat H, Dunstan C; Rebecca L Cooper Medical Research Foundation/Equipment Grant.

    2013

    • 2013 Australia-Harvard Fellowship; Zreiqat H; Harvard Club of Australia Foundation/Australia - Harvard Fellowship.
    • QX100 Droplet Digital PCR system for Shared Used at the Open Access, Multi-User Molecular Biology Core Facility; Richardson D, Kril J, Murphy C, Vandenberg R, Rendina L, Dos Remedios C, Ju Y, Kovacevic Z, Lyons G, Sutherland G, Lay P, Ammit A, Lai D, Morris B, Day M, Dong Q, Bao B, Huang M, Camp A, Boyer M, Whittington R, Byrne M, Hanrahan J, Fu D, Jansson P, Lane D, Bagley E, Hibbs D, Zhang D, Fraser S, Scolyer R, Black J, Halliday G, Christie M, Zreiqat H, Murray M, Slobedman B, Naylor M, Burgess J, Triccas J, Mason R, Chadban S, Combes V, Lovicu F, McLennan S, Kalinowski D, Sharland A, Johnstone D, Groundwater P, Dixon K, Zhou F, Lovejoy D, Lu Z, Zhu L, Goldsbury C, Witting P, Buckland M, Assinder S, Purdie (Williams) A, Codd R, Owens T, Hambly B; National Health and Medical Research Council (NHMRC)/Equipment Grants.
    • Microstructural Design Strategies for Repairing Traumatic Skeletal Injuries; Zreiqat H, Dunstan C; Rebecca L Cooper Medical Research Foundation/Equipment Grant.
    • A basis for building bone: Novel biomaterials for new bone growth; Zreiqat H; DVC Research/Bridging Support Grant.

    2012

    • Australia-Harvard Fellowship 2012; Zreiqat H; Harvard Club of Australia Foundation/Australia - Harvard Fellowship.
    • GeneAtlas Personal Microarray System; Richardson D, Scolyer R, Stocker R, Weninger W, Black J, Allen D, Murray M, Mason R, Twigg S, King N, Horvath L, Lovicu F, Lee C, Halliday G, Lovejoy D, Joshua D, Sharland A, Roufogalis B, Hambly B, Morris B, Bao B, Bishop A, Hibbs D, Lane D, Zhou F, Hanrahan J, Dixon K, Rendina L, Byrne M, Naylor M, Cole N, Jansson P, Dong Q, Codd R, Payne R, Assinder S, Chadban S, Fraser S, McLennan S, Suryo Rahmanto A, Lai D, Yu Y, Ju Y, Buckland M, Kovacevic Z, Saletta F, Zreiqat H, Kalinowski D, Groundwater P, Simes R, Zhang D, Boyer M, Murphy C; National Health and Medical Research Council (NHMRC)/Equipment Grants.

    2011

    • The small animal bioimager; Halliday G, Hambley T, Zreiqat H, Richardson D, Holst J, Rasko J, Byrne S, Dong Q, Hong A, Lyons G; National Health and Medical Research Council (NHMRC)/Equipment Grants.
    • The Instron testing material instrument (Model 5943); Dehghani F, Weiss A, Bilek M, Zreiqat H, Dunstan C, Chrzanowski W, Rohanizadeh R; National Health and Medical Research Council (NHMRC)/Equipment Grants.
    • Senior Research Fellowship A; Zreiqat H; National Health and Medical Research Council (NHMRC)/Career Awards: Research Fellowships.
    • Novel engineered nano-composite scaffolds for bone regeneration; Zreiqat H; Rebecca L Cooper Medical Research Foundation/Equipment Grant.

    2010

    • Novel coatings for orthopaedic application; Zreiqat H, Sonnabend D, Dunstan C; Australian Orthopaedic Association Research Foundation Ltd/Research Support.
    • Novel scaffolds for augmenting large bone defects; Zreiqat H; Rebecca L Cooper Medical Research Foundation/Equipment Grant.
    • Harnessing the physiological effects of strontium and zinc to produce novel biomaterials for orthopaedic applications; Zreiqat H, Dunstan C; National Health and Medical Research Council (NHMRC)/Project Grants.
    • Biomaterials for orthopaedic applications; Zreiqat H; DVC Research/Bridging Support Grant.
    • Tissue Engineering and Regenerative Medicine: The Next 20 years; Zreiqat H; DVC International/IPDF Grant.

    2009

    • Scaffolds for bone tissue regeneration and use in orthopaedic applications; Fick J, Pivonka P, Weston R, Brehm O, Zreiqat H, Wu C, Johnson K; Australian Research Council (ARC)/Linkage Projects (LP).
    • Developing Novel Scaffolds for Osteochondral Defects and Orthopaedic Prosthetic Coatings for Bone Tissue Regeneration and Implant Ossointegration; Zreiqat H; Rebecca L Cooper Medical Research Foundation/Equipment Grant.
    • Novel coatings for orthopaedic implants; Grau G, Little D, Zreiqat H, Dunstan C; National Health and Medical Research Council (NHMRC)/Project Grants.

    2008

    • Novel Scaffolds for repairing bone defects; Zreiqat H, Little D, Dunstan C; Australian Orthopaedic Association Research Foundation Ltd/Research Support.
    • Developing better treatment and novel prosthetic implants for joint replacement damaged due to arthritis; Zreiqat H; Rebecca L Cooper Medical Research Foundation/Research Support.

    2007

    • Rotor-Gene 6000, 5-Plex HRM with desktop computer & Gene-Disc 100 Stater Kit; Halliday G, Yue D, Sharland A, Bishop A, Stocker R, Bao B, McLennan S, Matsumoto I, Hambly B, Rose B, Harbour C, Ho J, Lee C, Twigg S, Soon L, Richardson D, King N, Zreiqat H; National Health and Medical Research Council (NHMRC)/Equipment Grants.
    • Micro-engineered biomaterials for improved orthopedic devices and scaffolds; Zreiqat H; University of Sydney/Bridging Support.
    • Effect of incorporating strontium into the surface of titanium alloy on bone cell behaviour; Zreiqat H; Australian Institute of Nuclear Science and Engineering (AINSE)/Research Grants.

    2006

    • Molecular Mechanisms Controlling The Maintenance And Differentiation Of Skeletal Tissue/Device Interface For Biomedical Engineering Applications; Zreiqat H; National Health and Medical Research Council (NHMRC)/Career Development Fellowships.
    • Histological testing of spinal implants � St. George Hospital; Zreiqat H, Diwan A; BLO University of New South Wales (Through Ortopaedic research Centre)/BLO Project.
    • Mechanisms of bone formation at the device / tissue interface; Zreiqat H, Haynes D; National Health and Medical Research Council (NHMRC)/Project Grants.
    • Histological services on retrieved femoral heads; Zreiqat H, Gillies M; Worley Parsons Services Pty Ltd/BLO Project.

    2005

    • Improving orthopaedic/dental devices by surface chemical modification; Zreiqat H, Swain M; Australian Research Council (ARC)/Discovery Projects (DP).
    • Mechanism of action of Zoledronnic acid in inflammatory arthritis; Zreiqat H, Binder W; Royal Australasian College of Physicians/Barbara Cameron ARA Fellowship.

    Selected publications

    Download citations: PDF RTF Endnote

    Edited Books

    • Zreiqat, H., Dunstan, C., Rosen, V. (2015). A Tissue Regneration Approach to Bone and Cartilage Repair. Cham: Springer.

    Book Chapters

    • Frohbergh, M., Newman, P., Simonaro, C., Zreiqat, H. (2015). Bone Tissue Engineering: Nanomedicine Approaches. In Robert A. Meyers (Eds.), Reviews in Cell Biology and Molecular Medicine, (pp. 153-178). Weinheim: Wiley - V C H Verlag GmbH & Co. KGaA. [More Information]
    • Lu, Z., Li, J., Zreiqat, H. (2015). Bone-Biomimetic Biomaterial and Cell Fate Determination. In Hala Zreiqat, Colin R. Dunstan, Vicki Rosen (Eds.), A Tissue Regneration Approach to Bone and Cartilage Repair, (pp. 119-146). Cham: Springer.
    • Lu, Z., Roohaniesfahani, S., Zreiqat, H. (2014). Mimicking Bone Microenvironment for Directing Adipose Tissue-Derived Mesenchymal Stem Cells into Osteogenic Differentiation. In Gordana Vunjak-Novakovic, Kursad Turksen (Eds.), Biomimetics and Stem Cells: Methods and Protocols, (pp. 161-171). New York: Springer Science+Business Media.
    • Roohaniesfahani, S., Zreiqat, H. (2012). Ceramic Scaffolds, Current Issues and Future Trends. In M Ramalingam, Z Haidar, S Ramakrishna, H Kobayashi, Y Haikel (Eds.), Integrated Biomaterials in Tissue Engineering, (pp. 25-46). Salem, MA: Scrivener Publishing.
    • Ma, W., Ruys, A., Zreiqat, H. (2009). Diamond-like carbon (DLC) as a biocompatible coating in orthopaedic and cardiac medicine. In L Di Silvio (Eds.), Cellular Response to Biomaterials, (pp. 391-426). Cambridge: Woodhead Publishing Limited.

    Journals

    • Roohaniesfahani, S., No, Y., Lu, Z., Ng, P., Chen, Y., Shi, J., Pavlos, N., Zreiqat, H. (2016). A bioceramic with enhanced osteogenic properties to regulate the function of osteoblastic and osteocalastic cells for bone tissue regeneration. Biomedical Materials, 11(3), 1-12. [More Information]
    • Roohaniesfahani, S., Newman, P., Zreiqat, H. (2016). Design and Fabrication of 3D printed Scaffolds with a Mechanical Strength Comparable to Cortical Bone to Repair Large Bone Defects. Scientific Reports, 6, 1-8. [More Information]
    • Rana, D., Zreiqat, H., Benkirane-Jessel, N., Ramakrishna, S., Ramalingam, M. (2016). Development of decellularized scaffolds for stem cell-driven tissue engineering [Forthcoming]. Journal of Tissue Engineering and Regenerative Medicine, 2015. [More Information]
    • Li, J., Roohaniesfahani, S., Dunstan, C., Quach, T., Steck, R., Saifzadeh, S., Pivonka, P., Zreiqat, H. (2016). Efficacy of novel synthetic bone substitutes in the reconstruction of large segmental bone defects in sheep tibiae. Biomedical Materials, 11(1), 1-12. [More Information]
    • Entezari, A., Roohaniesfahani, S., Zhang, Z., Zreiqat, H., Dunstan, C., Li, Q. (2016). Fracture behaviors of ceramic tissue scaffolds for load bearing applications. Scientific Reports, 6, 1-10. [More Information]
    • Graney, P., Roohaniesfahani, S., Zreiqat, H., Spiller, K. (2016). In vitro response of macrophages to ceramic scaffolds used for bone regeneration. Journal of the Royal Society Interface, 13(120), 1-12. [More Information]
    • Sehgal, R., Roohaniesfahani, S., Zreiqat, H., Banerjee, R. (2016). Nanostructured gellan and xanthan hydrogel depot integrated within a baghdadite scaffold augments bone regeneration [Forthcoming]. Journal of Tissue Engineering and Regenerative Medicine, 2015 (Article in Press). [More Information]
    • Li, J., Roohaniesfahani, S., Kim, K., Kaplan, D., Zreiqat, H. (2016). Silk coating on a bioactive ceramic scaffold for bone regeneration: Effective enhancement of mechanical and in vitro osteogenic properties towards load-bearing applications [Forthcoming]. Journal of Tissue Engineering and Regenerative Medicine, In press, 1-13. [More Information]
    • Li, J., Kim, K., Roohani-Esfahani, S., Guo, J., Kaplan, D., Zreiqat, H. (2015). A biphasic scaffold based on silk and bioactive ceramic with stratified properties for osteochondral tissue regeneration. Journal of Materials Chemistry B, 3(26), 5361-5376. [More Information]
    • Wang, G., Moya, S., Lu, Z., Gregurec, D., Zreiqat, H. (2015). Enhancing orthopedic implant bioactivity: Refining the Nanotopography. Nanomedicine, 10(8), 1327-1341. [More Information]
    • No, Y., Roohaniesfahani, S., Lu, Z., Schaer, T., Zreiqat, H. (2015). Injectable radiopaque and bioactive polycaprolactone-ceramic composites for orthopedic augmentation. Journal of Biomedical Materials Research. Part B: Applied Biomaterials, 103(7), 1465-1477. [More Information]
    • Kariem, H., Pastrama, M., Roohaniesfahani, S., Pivonka, P., Zreiqat, H., Hellmich, C. (2015). Micro-poro-elasticity of baghdadite-based bone tissue engineering scaffolds: A unifying approach based on ultrasonics, nanoindentation, and homogenization theory. Materials Science and Engineering C, 46(2015), 553-564. [More Information]
    • Newman, P., Lu, Z., Roohaniesfahani, S., Church, T., Biro, M., Davies, B., King, A., MacKenzie, K., Minett, A., Zreiqat, H. (2015). Porous and strong three-dimensional carbon nanotube coated ceramic scaffolds for tissue engineering. Journal of Materials Chemistry B, 3(42), 8337-8347. [More Information]
    • Lu, Z., Roohaniesfahani, S., Li, J., Zreiqat, H. (2015). Synergistic effect of nanomaterials and BMP-2 signalling in inducing osteogenic differentiation of adipose tissue-derived mesenchymal stem cells. Nanomedicine: Nanotechnology, Biology, and Medicine, 11(1), 219-228. [More Information]
    • Chen, Y., Roohaniesfahani, S., Lu, Z., Zreiqat, H., Dunstan, C. (2015). Zirconium Ions Up-Regulate the BMP/SMAD Signaling pathway and Promote the Proliferation and Differentiation of Human Osteoblasts. PloS One, 10(1), 1-17. [More Information]
    • Lu, Z., Wang, G., Roohaniesfahani, S., Dunstan, C., Zreiqat, H. (2014). Baghdadite Ceramics Modulate the Cross Talk Between Human Adipose Stem Cells and Osteoblasts for Bone Regeneration. Tissue Engineering. Part A, 20(5-6), 992-1002. [More Information]
    • Lu, Z., Wang, G., Zreiqat, H. (2014). Engineering Bone Niche Signals to Control Stem Cell Fate for Bone Tissue Regeneration. Archives of Stem Cell Research, 1(1), 1-2.
    • Roohaniesfahani, S., Wong, K., Lu, Z., Chen, Y., Li, J., Gronthos, S., Menicanin, D., Shi, J., Dunstan, C., Zreiqat, H. (2014). Fabrication of a novel triphasic and bioactive ceramic and evaluation of its in vitro and in vivo cytocompatibility and osteogenesis. Journal of Materials Chemistry B, 2(13), 1866-1878. [More Information]
    • Davies, B., King, A., Newman, P., Minett, A., Dunstan, C., Zreiqat, H. (2014). Hypothesis: Bones Toughness Arises from the Suppression of Elastic Waves. Scientific Reports, 4(7538), 1-6. [More Information]
    • No, Y., Roohaniesfahani, S., Zreiqat, H. (2014). Nanomaterials: the next step in injectable bone cements. Nanomedicine, 9(11), 1745-1764. [More Information]
    • Zhao, X., Wang, G., Zheng, H., Lu, Z., Cheng, X., Zreiqat, H. (2014). Refining naotopographical features on bone implant surfaces by altering surface chemical compositions. RSC Advances, 4(97), 54226-54234. [More Information]
    • Li, J., Kaplan, D., Zreiqat, H. (2014). Scaffold-based regeneration of skeletal tissues to meet clinical challenges. Journal of Materials Chemistry B, 2(42), 7272-7306. [More Information]
    • Newman, P., Roohaniesfahani, S., Zreiqat, H., Minett, A. (2014). See the extracellular forest for the nanotrees. Materials Today, 17(1), 43-44. [More Information]
    • Lu, Z., Wang, G., Dunstan, C., Chen, Y., Lu, W., Davies, B., Zreiqat, H. (2013). Activation and Promotion of Adipose Stem Cells by Tumour Necrosis Factor-Alpha Preconditioning for Bone Regeneration. Journal of Cellular Physiology, 228(8), 1737-1744. [More Information]
    • Newman, P., Minett, A., Ellis-Behnke, R., Zreiqat, H. (2013). Carbon nanotubes: Their potential and pitfalls for bone tissue regeneration and engineering. Nanomedicine: Nanotechnology, Biology, and Medicine, 9(8), 1139-1158. [More Information]
    • Zhao, X., Wang, G., Zheng, H., Lu, Z., Zhong, X., Cheng, X., Zreiqat, H. (2013). Delicate refinement of surface nanotopography by adjusting TiO2 coating chemical composition for enhanced interfacial biocompatibility. ACS Applied Materials and Interfaces, 5(16), 8203-8209. [More Information]
    • Roohaniesfahani, S., Chen, Y., Shi, J., Zreiqat, H. (2013). Fabrication and characterization of a new, strong and bioactive ceramic scaffold for bone regeneration. Materials Letters, 107, 378-381. [More Information]
    • Li, J., Gil, E., Hayden, R., Li, C., Roohaniesfahani, S., Kaplan, D., Zreiqat, H. (2013). Multiple Silk Coatings on Biphasic Calcium Phosphate Scaffolds: Effect on Physical and Mechanical Properties and In Vitro Osteogenic Response of Human Mesenchymal Stem Cells. Biomacromolecules, 14(7), 2179-2188. [More Information]
    • Wang, G., Lu, Z., Zhao, X., Kondyurin, A., Zreiqat, H. (2013). Ordered HAp nanoarchitecture formed on HAp-TCP bioceramics by "nanocarving" and mineralization deposition and its potential use for guiding cell behaviors. Journal of Materials Chemistry B, 1(19), 2455-2462. [More Information]
    • El Sayed, K., Marzahn, U., John, T., Hoyer, M., Zreiqat, H., Witthuhn, A., Kohl, B., Haisch, A., Schulze-Tanzil, G. (2013). PGA-associated heterotopic chondrocyte cocultures: implications of nasoseptal and auricular chondrocytes in articular cartilage repair. Journal of Tissue Engineering and Regenerative Medicine, 7(1), 61-72. [More Information]
    • Zhang, W., Wang, G., Liu, Y., Zhao, X., Zou, D., Zhu, C., Jin, Y., Huang, Q., Sun, J., Liu, X., Xinquan, J., Zreiqat, H. (2013). The synergistic effect of hierarchical micro/nano-topography and bioactive ions for enhanced osseointegration. Biomaterials, 34(13), 3184-3195. [More Information]
    • Roohaniesfahani, S., Dunstan, C., Li, J., Lu, Z., Davies, B., Pearce, S., Field, J., Williams, R., Zreiqat, H. (2013). Unique microstructural design of ceramic scaffolds for bone regeneration under load. Acta Biomaterialia, 9(6), 7014-7024. [More Information]
    • Wang, G., Lu, Z., Xie, K., Lu, W., Roohaniesfahani, S., Kondyurin, A., Zreiqat, H. (2012). A facile method to in situ formation of hydroxyapatite single crystal architecture for enhanced osteoblast adhesion. Journal of Materials Chemistry, 22(36), 19081-19087. [More Information]
    • Lu, Z., Roohaniesfahani, S., Wang, G., Zreiqat, H. (2012). Bone biomimetic microenvironment induces osteogenic differentiation of adipose tissue-derived mesenchymal stem cells. Nanomedicine: Nanotechnology, Biology, and Medicine, 8(4), 507-515. [More Information]
    • Roohaniesfahani, S., Lu, Z., Li, J., Ellis-Behnke, R., Kaplan, D., Zreiqat, H. (2012). Effect of self-assembled nanofibrous silk/polycaprolactone layer on the osteoconductivity and mechanical properties of biphasic calcium phosphate scaffolds. Acta Biomaterialia, 8(1), 302-312. [More Information]
    • Waterhouse, A., Wise, S., Yin, Y., Wu, B., James, B., Zreiqat, H., McKenzie, D., Bao, B., Weiss, A., Ng, M., Bilek, M. (2012). In vivo biocompatibility of a plasma-activated, coronary stent coating. Biomaterials, 33(32), 7984-7992. [More Information]
    • Roohaniesfahani, S., Nouri-Khorasani, S., Lu, Z., Fathi, M., Razavi, M., Appleyard, R., Zreiqat, H. (2012). Modification of Porous Calcium Phosphate Surfaces with Different Geometries of Bioactive Glass Nanoparticles. Materials Science and Engineering C, 32(4), 830-839. [More Information]
    • Wang, G., Lu, Z., Dwarte, D., Zreiqat, H. (2012). Porous scaffolds with tailored reactivity modulate in-vitro osteoblast responses. Materials Science and Engineering C, 32(7), 1818-1826. [More Information]
    • Roohaniesfahani, S., Dunstan, C., Davies, B., Pearce, S., Williams, R., Zreiqat, H. (2012). Repairing a critical-sized bone defect with highly porous modified and unmodified baghdadite scaffolds. Acta Biomaterialia, 8(11), 4162-4172. [More Information]
    • Lu, Z., Wang, G., Dunstan, C., Zreiqat, H. (2012). Short-Term Exposure to Tumor Necrosis Factor-Alpha Enables Human Osteoblasts to Direct Adipose Tissue-Derived Mesenchymal Stem Cells into Osteogenic Differentiation. Stem Cells and Development, 21(13), 2420-2429. [More Information]
    • Zhong, X., Lu, Z., Valtchev, P., Wei, H., Zreiqat, H., Dehghani, F. (2012). Surface modification of poly(propylene carbonate) by aminolysis and layer-by-layer assembly for enhanced cytocompatibility. Colloids And Surfaces B: Biointerfaces, 93(1), 75-84. [More Information]
    • Roohaniesfahani, S., Nouri-Khorasani, S., Lu, Z., Appleyard, R., Zreiqat, H. (2011). Effects of Bioactive Glass Nanoparticles on the Mechanical and Biological Behavior of Composite Coated Scaffolds. Acta Biomaterialia, 7(3), 1307-1318. [More Information]
    • Wang, G., Liu, X., Zreiqat, H., Ding, C. (2011). Enhanced effects of nano-scale topography on the bioactivity and osteoblast behaviors of micron rough ZrO2 coatings. Colloids And Surfaces B: Biointerfaces, 86(2), 267-274. [More Information]
    • Wang, G., Lu, Z., Liu, X., Zhou, X., Ding, C., Zreiqat, H. (2011). Nanostructured glass-ceramic coatings for orthopaedic applications. Journal of the Royal Society Interface, 8(61), 1192-1203. [More Information]
    • Roohaniesfahani, S., Lu, Z., Zreiqat, H. (2011). Novel, simple and reproducible method for preparation of composite hierarchal porous structure scaffolds. Materials Letters, 65(17-18), 2578-2581. [More Information]
    • Lu, Z., Roohaniesfahani, S., Kwok, P., Zreiqat, H. (2011). Osteoblasts on Rod Shaped Hydroxyapatite Nanoparticles Incorporated PCL Film Provide an Optimal Osteogenic Niche for Stem Cell Differentiation. Tissue Engineering. Part A, 17(11/12), 1651-1661. [More Information]
    • Lu, Z., Zreiqat, H. (2010). Beta-tricalcium phosphate exerts osteoconductivity through α2β1 integrin and down-stream MAPK/ERK signaling pathway. Biochemical and Biophysical Research Communications, 394(2), 323-329. [More Information]
    • Wu, C., Chang, J., Zreiqat, H. (2010). Engineered Ca-Si Based Ceramics for Skeletal Tissue Reconstruction. Materials Science Foundations (monograph series), 62, 122-149. [More Information]
    • Wang, G., Zreiqat, H. (2010). Functional Coatings or Films for Hard-Tissue Applications. Materials, 3(7), 3994-4050. [More Information]
    • Wu, C., Zreiqat, H. (2010). Porous bioactive diopside (CaMgSi2O6) ceramic microspheres for drug delivery. Acta Biomaterialia, 6(3), 820-829. [More Information]
    • Wu, C., Ramaswamy, Y., Zreiqat, H. (2010). Porous diopside (CaMgSi2O6) scaffold: A promising bioactive material for bone tissue engineering. Acta Biomaterialia, 6(6), 2237-2245. [More Information]
    • Zreiqat, H., Yang, C., James, B., Duflou, J., Lowe, H. (2010). Probable endothelisation of bare metal stent struts extending from the left main coronary into the aorta. Journal of Thrombosis and Thrombolysis, 30(4), 500-501. [More Information]
    • Zreiqat, H., Belluoccio, D., Smith, M., Wilson, R., Rowley, L., Jones, K., Ramaswamy, Y., Vogl, T., Roth, J., Bateman, J., Little, C. (2010). S100A8 and S100A9 in experimental osteoarthritis. Arthritis Research & Therapy, 12(1), 1-13. [More Information]
    • Zreiqat, H., Ramaswamy, Y., Wu, C., Paschalidis, A., Lu, Z., James, B., Birke, O., McDonald, M., Little, D., Dunstan, C. (2010). The incorporation of strontium and zinc into a calcium-silicon ceramic for bone tissue engineering. Biomaterials, 31(12), 3175-3184. [More Information]
    • Roohaniesfahani, S., Nouri-Khorasani, S., Lu, Z., Appleyard, R., Zreiqat, H. (2010). The influence hydroxyapatite nanoparticle shape and size on the properties of biphasic calcium phosphate scaffolds coated with hydroxyapatite-PCL composites. Biomaterials, 31(21), 5498-5509. [More Information]
    • Lu, Z., Zreiqat, H. (2010). The Osteoconductivity of Biomaterials Is Regulated by Bone Morphogenetic Protein 2 Autocrine Loop Involving α2β1 Integrin and Mitogen-Activated Protein Kinase/Extracellular Related Kinase Signaling Pathways. Tissue Engineering. Part A, 16(10), 3075-3084. [More Information]
    • Wang, C., Karlis, G., Anderson, G., Dunstan, C., Carbone, A., Berger, G., Ploska, U., Zreiqat, H. (2009). Bone growth is enhanced by novel bioceramic coatings on Ti alloy implants. Journal of Biomedical Materials Research. Part A, 90A(2), 419-428. [More Information]
    • Schulze-Tanzil, G., Zreiqat, H., Sabat, R., Kohl, B., Halder, A., Muller, R., John, T. (2009). Interleukin-10 and articular cartilage: Experimental therapeutical approaches in cartilage disorders. Current Gene Therapy: the international journal for in-depth reviews on gene therapy, 9(4), 631-315. [More Information]
    • Ramaswamy, Y., Wu, C., Zreiqat, H. (2009). Orthopedic coating materials: Considerations and applications. Expert Review of Medical Devices, 6(4), 423-430. [More Information]
    • Wu, C., Ramaswamy, Y., Liu, X., Wang, G., Zreiqat, H. (2009). Plasma-sprayed CaTiSiO5 ceramic coating on Ti-6AI-4V with excellent bonding strength, stability and cellular bioactivity. Journal of the Royal Society Interface, 6(1), 159-168. [More Information]
    • Ramaswamy, Y., Wu, C., Dunstan, C., Hewson, B., Eindorf, T., Anderson, G., Zreiqat, H. (2009). Sphene ceramics for orthopedic coating applications: An in vitro and in vivo study. Acta Biomaterialia, 5(8), 3192-3204. [More Information]
    • Wu, C., Ramaswamy, Y., Zhu, Y., Zheng, R., Appleyard, R., Howard, A., Zreiqat, H. (2009). The effect of mesoporous bioactive glass on the physiochemical, biological and drug-release properties of poly(DL-lactide-co-glycolide) films. Biomaterials, 30(12), 2199-2208. [More Information]
    • Zreiqat, H., James, B., Brieger, D., Kritharides, L., Lowe, H. (2008). Acute coronary stent thrombosis: Toward insights into possible mechanism using novel imaging methods. Thrombosis and Haemostasis, 99(5), 976-977. [More Information]
    • Ramaswamy, Y., Wu, C., Zhou, H., Zreiqat, H. (2008). Biological response of human bone cells to zinc-modified Ca-Si-based ceramics. Acta Biomaterialia, 4(5), 1487-1497. [More Information]
    • McMahon, A., Zreiqat, H., Lowe, H. (2008). Carotid artery stenting in the Zucker rat: a novel, potentially 'diabetes-specific' model of in-stent restenosis. Diabetes and Vascular Disease Research, 5(2), 145-146. [More Information]
    • Helary, G., Poussard, L., Zreiqat, H., Migonney, V. (2008). Functionalization of biomaterials for joint implant application. Bio-Medical Materials and Engineering, 18, 237-239. [More Information]
    • Wu, C., Ramaswamy, Y., Boughton, P., Zreiqat, H. (2008). Improvement of mechanical and biological properties of porous CaSiO3 scaffolds by poly(D,L-lactic acid) modification. Acta Biomaterialia, 4(2), 343-353. [More Information]
    • Wu, C., Ramaswamy, Y., Gail, D., Yang, W., Xiao, K., Zhang, L., Yin, Y., Zreiqat, H. (2008). Novel sphene coatings on Ti-6Al-4V for orthopaedic implants using sol-gel method. Acta Biomaterialia, 4, 569-576. [More Information]
    • Zhu, Y., Wu, C., Ramaswamy, Y., Kockrick, E., Simon, P., Kaskel, S., Zreiqat, H. (2008). Preparation, characterization and in vitro bioactivity of mesoporous bioactive glasses (MBGs) scaffolds for bone tissue engineering. Microporous and Mesoporous Materials, 112, 494-503.
    • Wu, C., Ramaswamy, Y., Chang, J., Woods, J., Chen, Y., Zreiqat, H. (2008). The Effect of Zn Contents on Phase Composition, Chemical Stability and Cellular Bioactivity in Zn-Ca-Si System Ceramics. Journal of Biomedical Materials Research. Part B: Applied Biomaterials, 87(2), 346-353. [More Information]
    • Ramaswamy, Y., Wu, C., Van Hummel, A., Combes, V., Grau, G., Zreiqat, H. (2008). The responses of osteoblasts, osteoclasts and endothelial cells to zirconium modified calcium-silicate-based ceramic. Biomaterials, 29(33), 4392-4402. [More Information]
    • Oberholzer, A., John, T., Kohl, B., Gust, T., Muller, R., La Face, D., Hutchins, B., Zreiqat, H., Ertel, W., Schulze-Tanzil, G. (2007). Adenoviral transduction is more efficient in alginate-derived chondrocytes than in monolayer chondrocytes. Cell and Tissue Research, 328(2), 383-390. [More Information]
    • Ma, W., Ruys, A., Mason, R., Martin, P., Bendavid, A., Liu, Z., Ionescu, M., Zreiqat, H. (2007). DLC coatings: Effects of physical and chemical properties on biological response. Biomaterials, 28(9), 1620-1628. [More Information]
    • Wu, C., Ramaswamy, Y., Soeparto, A., Zreiqat, H. (2007). Incorporation of titanium into calcium silicate improved their chemical stability and biological properties. Journal of Biomedical Materials Research. Part A, 86(2 (Online article 29 Oct 2007)), 402-410. [More Information]
    • John, T., Muller, R., Oberholzer, A., Zreiqat, H., Kohl, B., Ertel, W., Hostmann, A., Tschoeke, S., Schulze-Tanzil, G. (2007). Interleukin-10 modulates pro-apoptotic effects of TNF-alpha in human articular chondrocytes in vitro. Cytokine, 40(3), 226-234. [More Information]
    • Wu, C., Zreiqat, H. (2007). Preparation and Characteristics of Strontium Containing Bioactive CaSiO3 Ceramics. Key Engineering Materials, 330-332(I), 499-502.
    • Zreiqat, H., Howlett, C., Gronthos, S., Hume, D., Geczy, C. (2007). S100A8/S100A9 and their association with cartilage and bone. Journal of Molecular Histology, 38(5), 381-391. [More Information]
    • Wu, C., Ramaswamy, Y., Kwik, D., Zreiqat, H. (2007). The effect of strontium incorporation into CaSiO3 ceramics on their physical and biological properties. Biomaterials, 28(21), 3171-3181. [More Information]
    • Knabe, C., Kraska, B., Koch, C., Gross, U., Zreiqat, H., Stiller, M. (2006). A method for immunohistochemical detection of osteogenic markers in undecalcified bone sections. Biotechnic and Histochemistry, 81(1), 31-39.
    • Ma, W., Ruys, A., Mason, R., Martin, P., Bendavid, A., Liu, Z., Ionescu, M., Zreiqat, H. (2006). DLC coatings: Effects of physical and chemical properties on biological response. Biomaterials, 28(9), 1620-1628. [More Information]
    • Ramaswamy, W., Ben-Nissan, B., Roest, R., Haynes, D., Zreiqat, H. (2006). Human osteoclasts behaviour on sol-gel derived carbonate hydroxyapatite coatings on anodized titanium alloy substrates. Key Engineering Materials, 309-311, 709-712.
    • Ramaswamy, Y., Haynes, D., Berger, G., Gildenhaar, R., Lucas, H., Holding, C., Zreiqat, H. (2005). Bioceramics composition modulate resorption of human osteoclasts. Journal of Materials Science: Materials in Medicine, 16, 1199-1205. [More Information]
    • Zreiqat, H., Roest, R., Valenzuela, S., Milev, A., Ben-Nissan, B. (2005). Human Bone Derived Cell (HBDC) behaviour of sol-gel derived carbonate hydroxyapatite coatings on titanium alloy substrates. Key Engineering Materials, 284-286, 541-544.
    • McCormick, M., Rahimi, F., Bobryshev,, Y., Gaus, K., Zreiqat, H., Cai, H., Lord,, R., Geczy, C. (2005). S100A8 and S100A9 in Human Arterial Wall: implications for atherogenesis. Journal of Biological Chemistry, 280(50), 41521-41529.
    • Knabe, C., Stiller, M., Berger, G., Reif, D., Gildenhaar, R., Hewlett, C., Zreiqat, H. (2005). The effect of bioactive glass ceramics on the expression of bone-related genes and proteins in vitro. Clinical Oral Implants Research, 16(1), 119-127.
    • Zreiqat, H., Valenzuela, S., Ben-Nissan, B., Roest, R., Knabe, C., Radlanski, R., Renz, H., Evans, P. (2005). The effect of surface chemistry modification of titanium alloy on signalling pathways in human osteoblasts. Biomaterials, 26(36), 7579-7586. [More Information]
    • Knabe, C., Berger, G., Gildenhaar, R., Meyer, J., Hewlett, C., Markovic, B., Zreiqat, H. (2004). Effect of rapidly resorbable calcium phosphates and a calcium phosphate bone cement on the expression of bone-related genes and proteins in vitro. Journal of Biomedical Materials Research. Part A, 69A(1), 145-154.
    • Crotti, T., Smith, M., Findlay, D., Zreiqat, H., Ahern, M., Weedon, H., Hatzinikolous, G., Capone, M., Holding, C., Haynes, D. (2004). Factors regulating osteoclast formation in human tissues adjacent to peri-implant bone loss: expression of receptor activator NFκB, RANK ligand and osteoprotegerin. Biomaterials, 25(4), 565-573.
    • Wang, C., Duan, Y., Markovic, B., Barbara, J., Hewlett, C., Zhang, X., Zreiqat, H. (2004). Phenotypic expression of bone-related genes in osteoblasts grown on calcium phosphate ceramics with different phase compositions. Biomaterials, 25(13), 2507-2514. [More Information]
    • Wang, C., Duan, Y., Markovic, B., Barbara, J., Hewlett, C., Zhang, X., Zreiqat, H. (2004). Proliferation and bone-related gene expression of osteoblasts grown on hydroxyapatite ceramics sintered at different temperature. Biomaterials, 25(15), 2949-2956. [More Information]
    • Wang, C., Duan, Y., Markovic, B., Barbara, J., Hewlett, C., Zhang, X., Zreiqat, H. (2004). Quantitative Analysis of Osteoprotegerin and RANKL Expression in Osteoblast Grown on Different Calcium Phosphate Ceramics. Key Engineering Materials, 254-256, 713-716.
    • Haynes, D., Crotti, T., Zreiqat, H. (2004). Regulation of osteoclast activity in peri-implant tissues. Biomaterials, 25(20), 4877-4885. [More Information]
    • Knabe, C., Hewlett, C., Klar, F., Zreiqat, H. (2004). The effect of different titanium and hydroxyapatite-coated dental implant surfaces on phenotypic expression of human bone-derived cells. Journal of Biomedical Materials Research. Part A, 71A(1), 98-107. [More Information]
    • Zreiqat, H., Berger, G., Gildenhaar, R., Knabe, C. (2004). The Functional Expression of Human Bone-Derived Cells Grown on Rapidly Resorbable Calcium Phosphate Ceramics. Key Engineering Materials, 254-256, 1059-1062.
    • Knabe, C., Berger, G., Gildenhaar, R., Hewlett, C., Markovic, B., Zreiqat, H. (2004). The functional expression of human bone-derived cells grown on rapidly resorbable calcium phosphate ceramics. Biomaterials, 25, 335-344.
    • Knabe, C., Berger, G., Gildenhaar, R., Klar, F., Zreiqat, H. (2004). The modulation of osteogenesis in vitro by calcium titanium phosphate coatings. Biomaterials, 25(20), 4911-4919. [More Information]
    • Zreiqat, H., Ahu Akin, F., Hewlett, C., Markovic, B., Haynes, D., Lateef, S., Hanley, L. (2003). Differentiation of human bone-derived cells grown on GRGDSP-peptide bound titanium surfaces. Journal of Biomedical Materials Research. Part A, 64A(1), 105-113.
    • Zreiqat, H., Kumar, R., Markovic, B., Zicat, B., Hewlett, C. (2003). Macrophages at the skeletal tissue-device interface of loosened prosthetic devices express bone-related genes and their products. Journal of Biomedical Materials Research. Part A, 65A(1), 109-117.
    • Zreiqat, H., Crotti, T., Hewlett, C., Capone, M., Markovic, B., Haynes, D. (2003). Prosthetic particles modify the expression of bone-related proteins by human osteoblastic cells in vitro. Biomaterials, 24, 337-346.
    • Zreiqat, H., Hewlett, C., Zannettino, A., Evans, P., Knabe, C., Schulze-Tanzil, G., Shakibaei, G. (2003). Surface modification of bioceramics affect osteoblastic cells response. Key Engineering Materials, 240-242, 707-710.
    • Knabe, C., Hewlett, C., Markovic, B., Gildenhaar, R., Berger, G., Zreiqat, H. (2003). The functional expression of osteoblasts grown on rapidly resorbable calcium phosphates. Key Engineering Materials, 240-242(-), 679-682.
    • Zreiqat, H., Hewlett, C., Zannettino, A., Evans, P., Schulze-Tanzil, G., Knabe, C., Shakibaei, G. (2002). Mechanisms of magnesium-stimulated adhesion of osteoblastic cells to commonly used orthopaedic implants. Journal of Biomedical Materials Research. Part B: Applied Biomaterials, 62, 175-184.

    Conferences

    • Roohaniesfahani, S., Wong, K., Lu, Z., Li, J., Zreiqat, H. (2012). Introducing Magnesium Silicate Based Scaffolds. International Forum of Biomedical Materials: Nanobiomaterials for Tissue Regeneration, China: Zhejiang University.
    • Roohaniesfahani, S., Wong, K., Lu, Z., Li, J., Zreiqat, H. (2012). Magnesium Silicate Scaffolds: a New Candidate Biomaterial for Bone Regeneration (ID:3072). 9th World Biomaterials Congress, China: World Biomaterials Congress.
    • Roohaniesfahani, S., Lu, Z., Li, J., Appleyard, R., Zreiqat, H. (2010). Enhancing Mechanical and Biological Behavior of Strontium-Doped Hardystonite Scaffolds with Nanocomposite Coating. TERMIS 2010, Orlando, Florida, United States of America.
    • Wang, G., Lu, Z., Liu, X., Zhou, X., Ding, C., Zreiqat, H. (2010). Nanostructured Biomedical Coatings for Orthopaedic Applications. 3rd Sydney University Tissue Engineering Network Symposium SuTEN 2010, Australia: University of Sydney.
    • Wang, G., Lu, Z., Liu, X., Zhou, X., Ding, C., Zreiqat, H. (2010). Nanostructured glass-ceramic coatings for orthopaedic applications. 15th Annual Scientific Meeting of the Australian and New Zealand Orthopaedic Research Society ANZORS 2010, Australia: Australian and New Zealand Orthopaedic Research Society.
    • Li, J., Roohaniesfahani, S., Lu, Z., Wang, G., Kaplan, D., Zreiqat, H. (2010). Novel Silk-Modified Strontium-Hardystonite Composite Scaffolds for Skeletal Regeneration. TERMIS - North America 2010 Conference on Tissue Engineering & Regenerative Medicine International Society, USA: Tissue Engineering & Regenerative Medicine International Society.
    • Li, J., Roohaniesfahani, S., Lu, Z., Wang, G., Kaplan, D., Zreiqat, H. (2010). Silk-Modified Strontium-Hardystonite Scaffolds for Bone Tissue Engineering. 3rd Sydney University Tissue Engineering Network Symposium SuTEN 2010, Australia: University of Sydney.
    • Ma, W., Ruys, A., Zreiqat, H., Mason, R., Ringer, S., Liu, Z., Keast, V., Martin, P., Bendavid, A. (2006). The Biocompatibility of Diamond-Like Carbon Nano Films. International Conference on Nanoscience and Nanotechnology 2006, Brisbane, Australia: (IEEE) Institute of Electrical and Electronics Engineers.

    Patents

    • Zreiqat, H., Wu, C., Ramaswamy, Y. (2009). Preparation and application of novel Baghdadite (Ca3ZrSi2O9) Scaffolds and coatings for skeletal tissue regeneration. Patent No. WO/2009/052583. Worldwide.

    Magazine / Newspaper Articles

    • Lu, W., McKenzie, D., Dunstan, C., Zreiqat, H., Bilek, M. (2012). Plasma Immersion Ion Implantation Treatment of Poly-ether Ether Ketone for the Immobilization of Biomolecules on Surfaces (ID: 836). International Forum of Biomedical Materials: Nanobiomaterials for Tissue Regeneration.

    2016

    • Roohaniesfahani, S., No, Y., Lu, Z., Ng, P., Chen, Y., Shi, J., Pavlos, N., Zreiqat, H. (2016). A bioceramic with enhanced osteogenic properties to regulate the function of osteoblastic and osteocalastic cells for bone tissue regeneration. Biomedical Materials, 11(3), 1-12. [More Information]
    • Roohaniesfahani, S., Newman, P., Zreiqat, H. (2016). Design and Fabrication of 3D printed Scaffolds with a Mechanical Strength Comparable to Cortical Bone to Repair Large Bone Defects. Scientific Reports, 6, 1-8. [More Information]
    • Rana, D., Zreiqat, H., Benkirane-Jessel, N., Ramakrishna, S., Ramalingam, M. (2016). Development of decellularized scaffolds for stem cell-driven tissue engineering [Forthcoming]. Journal of Tissue Engineering and Regenerative Medicine, 2015. [More Information]
    • Li, J., Roohaniesfahani, S., Dunstan, C., Quach, T., Steck, R., Saifzadeh, S., Pivonka, P., Zreiqat, H. (2016). Efficacy of novel synthetic bone substitutes in the reconstruction of large segmental bone defects in sheep tibiae. Biomedical Materials, 11(1), 1-12. [More Information]
    • Entezari, A., Roohaniesfahani, S., Zhang, Z., Zreiqat, H., Dunstan, C., Li, Q. (2016). Fracture behaviors of ceramic tissue scaffolds for load bearing applications. Scientific Reports, 6, 1-10. [More Information]
    • Graney, P., Roohaniesfahani, S., Zreiqat, H., Spiller, K. (2016). In vitro response of macrophages to ceramic scaffolds used for bone regeneration. Journal of the Royal Society Interface, 13(120), 1-12. [More Information]
    • Sehgal, R., Roohaniesfahani, S., Zreiqat, H., Banerjee, R. (2016). Nanostructured gellan and xanthan hydrogel depot integrated within a baghdadite scaffold augments bone regeneration [Forthcoming]. Journal of Tissue Engineering and Regenerative Medicine, 2015 (Article in Press). [More Information]
    • Li, J., Roohaniesfahani, S., Kim, K., Kaplan, D., Zreiqat, H. (2016). Silk coating on a bioactive ceramic scaffold for bone regeneration: Effective enhancement of mechanical and in vitro osteogenic properties towards load-bearing applications [Forthcoming]. Journal of Tissue Engineering and Regenerative Medicine, In press, 1-13. [More Information]

    2015

    • Li, J., Kim, K., Roohani-Esfahani, S., Guo, J., Kaplan, D., Zreiqat, H. (2015). A biphasic scaffold based on silk and bioactive ceramic with stratified properties for osteochondral tissue regeneration. Journal of Materials Chemistry B, 3(26), 5361-5376. [More Information]
    • Zreiqat, H., Dunstan, C., Rosen, V. (2015). A Tissue Regneration Approach to Bone and Cartilage Repair. Cham: Springer.
    • Frohbergh, M., Newman, P., Simonaro, C., Zreiqat, H. (2015). Bone Tissue Engineering: Nanomedicine Approaches. In Robert A. Meyers (Eds.), Reviews in Cell Biology and Molecular Medicine, (pp. 153-178). Weinheim: Wiley - V C H Verlag GmbH & Co. KGaA. [More Information]
    • Lu, Z., Li, J., Zreiqat, H. (2015). Bone-Biomimetic Biomaterial and Cell Fate Determination. In Hala Zreiqat, Colin R. Dunstan, Vicki Rosen (Eds.), A Tissue Regneration Approach to Bone and Cartilage Repair, (pp. 119-146). Cham: Springer.
    • Wang, G., Moya, S., Lu, Z., Gregurec, D., Zreiqat, H. (2015). Enhancing orthopedic implant bioactivity: Refining the Nanotopography. Nanomedicine, 10(8), 1327-1341. [More Information]
    • No, Y., Roohaniesfahani, S., Lu, Z., Schaer, T., Zreiqat, H. (2015). Injectable radiopaque and bioactive polycaprolactone-ceramic composites for orthopedic augmentation. Journal of Biomedical Materials Research. Part B: Applied Biomaterials, 103(7), 1465-1477. [More Information]
    • Kariem, H., Pastrama, M., Roohaniesfahani, S., Pivonka, P., Zreiqat, H., Hellmich, C. (2015). Micro-poro-elasticity of baghdadite-based bone tissue engineering scaffolds: A unifying approach based on ultrasonics, nanoindentation, and homogenization theory. Materials Science and Engineering C, 46(2015), 553-564. [More Information]
    • Newman, P., Lu, Z., Roohaniesfahani, S., Church, T., Biro, M., Davies, B., King, A., MacKenzie, K., Minett, A., Zreiqat, H. (2015). Porous and strong three-dimensional carbon nanotube coated ceramic scaffolds for tissue engineering. Journal of Materials Chemistry B, 3(42), 8337-8347. [More Information]
    • Lu, Z., Roohaniesfahani, S., Li, J., Zreiqat, H. (2015). Synergistic effect of nanomaterials and BMP-2 signalling in inducing osteogenic differentiation of adipose tissue-derived mesenchymal stem cells. Nanomedicine: Nanotechnology, Biology, and Medicine, 11(1), 219-228. [More Information]
    • Chen, Y., Roohaniesfahani, S., Lu, Z., Zreiqat, H., Dunstan, C. (2015). Zirconium Ions Up-Regulate the BMP/SMAD Signaling pathway and Promote the Proliferation and Differentiation of Human Osteoblasts. PloS One, 10(1), 1-17. [More Information]

    2014

    • Lu, Z., Wang, G., Roohaniesfahani, S., Dunstan, C., Zreiqat, H. (2014). Baghdadite Ceramics Modulate the Cross Talk Between Human Adipose Stem Cells and Osteoblasts for Bone Regeneration. Tissue Engineering. Part A, 20(5-6), 992-1002. [More Information]
    • Lu, Z., Wang, G., Zreiqat, H. (2014). Engineering Bone Niche Signals to Control Stem Cell Fate for Bone Tissue Regeneration. Archives of Stem Cell Research, 1(1), 1-2.
    • Roohaniesfahani, S., Wong, K., Lu, Z., Chen, Y., Li, J., Gronthos, S., Menicanin, D., Shi, J., Dunstan, C., Zreiqat, H. (2014). Fabrication of a novel triphasic and bioactive ceramic and evaluation of its in vitro and in vivo cytocompatibility and osteogenesis. Journal of Materials Chemistry B, 2(13), 1866-1878. [More Information]
    • Davies, B., King, A., Newman, P., Minett, A., Dunstan, C., Zreiqat, H. (2014). Hypothesis: Bones Toughness Arises from the Suppression of Elastic Waves. Scientific Reports, 4(7538), 1-6. [More Information]
    • Lu, Z., Roohaniesfahani, S., Zreiqat, H. (2014). Mimicking Bone Microenvironment for Directing Adipose Tissue-Derived Mesenchymal Stem Cells into Osteogenic Differentiation. In Gordana Vunjak-Novakovic, Kursad Turksen (Eds.), Biomimetics and Stem Cells: Methods and Protocols, (pp. 161-171). New York: Springer Science+Business Media.
    • No, Y., Roohaniesfahani, S., Zreiqat, H. (2014). Nanomaterials: the next step in injectable bone cements. Nanomedicine, 9(11), 1745-1764. [More Information]
    • Zhao, X., Wang, G., Zheng, H., Lu, Z., Cheng, X., Zreiqat, H. (2014). Refining naotopographical features on bone implant surfaces by altering surface chemical compositions. RSC Advances, 4(97), 54226-54234. [More Information]
    • Li, J., Kaplan, D., Zreiqat, H. (2014). Scaffold-based regeneration of skeletal tissues to meet clinical challenges. Journal of Materials Chemistry B, 2(42), 7272-7306. [More Information]
    • Newman, P., Roohaniesfahani, S., Zreiqat, H., Minett, A. (2014). See the extracellular forest for the nanotrees. Materials Today, 17(1), 43-44. [More Information]

    2013

    • Lu, Z., Wang, G., Dunstan, C., Chen, Y., Lu, W., Davies, B., Zreiqat, H. (2013). Activation and Promotion of Adipose Stem Cells by Tumour Necrosis Factor-Alpha Preconditioning for Bone Regeneration. Journal of Cellular Physiology, 228(8), 1737-1744. [More Information]
    • Newman, P., Minett, A., Ellis-Behnke, R., Zreiqat, H. (2013). Carbon nanotubes: Their potential and pitfalls for bone tissue regeneration and engineering. Nanomedicine: Nanotechnology, Biology, and Medicine, 9(8), 1139-1158. [More Information]
    • Zhao, X., Wang, G., Zheng, H., Lu, Z., Zhong, X., Cheng, X., Zreiqat, H. (2013). Delicate refinement of surface nanotopography by adjusting TiO2 coating chemical composition for enhanced interfacial biocompatibility. ACS Applied Materials and Interfaces, 5(16), 8203-8209. [More Information]
    • Roohaniesfahani, S., Chen, Y., Shi, J., Zreiqat, H. (2013). Fabrication and characterization of a new, strong and bioactive ceramic scaffold for bone regeneration. Materials Letters, 107, 378-381. [More Information]
    • Li, J., Gil, E., Hayden, R., Li, C., Roohaniesfahani, S., Kaplan, D., Zreiqat, H. (2013). Multiple Silk Coatings on Biphasic Calcium Phosphate Scaffolds: Effect on Physical and Mechanical Properties and In Vitro Osteogenic Response of Human Mesenchymal Stem Cells. Biomacromolecules, 14(7), 2179-2188. [More Information]
    • Wang, G., Lu, Z., Zhao, X., Kondyurin, A., Zreiqat, H. (2013). Ordered HAp nanoarchitecture formed on HAp-TCP bioceramics by "nanocarving" and mineralization deposition and its potential use for guiding cell behaviors. Journal of Materials Chemistry B, 1(19), 2455-2462. [More Information]
    • El Sayed, K., Marzahn, U., John, T., Hoyer, M., Zreiqat, H., Witthuhn, A., Kohl, B., Haisch, A., Schulze-Tanzil, G. (2013). PGA-associated heterotopic chondrocyte cocultures: implications of nasoseptal and auricular chondrocytes in articular cartilage repair. Journal of Tissue Engineering and Regenerative Medicine, 7(1), 61-72. [More Information]
    • Zhang, W., Wang, G., Liu, Y., Zhao, X., Zou, D., Zhu, C., Jin, Y., Huang, Q., Sun, J., Liu, X., Xinquan, J., Zreiqat, H. (2013). The synergistic effect of hierarchical micro/nano-topography and bioactive ions for enhanced osseointegration. Biomaterials, 34(13), 3184-3195. [More Information]
    • Roohaniesfahani, S., Dunstan, C., Li, J., Lu, Z., Davies, B., Pearce, S., Field, J., Williams, R., Zreiqat, H. (2013). Unique microstructural design of ceramic scaffolds for bone regeneration under load. Acta Biomaterialia, 9(6), 7014-7024. [More Information]

    2012

    • Wang, G., Lu, Z., Xie, K., Lu, W., Roohaniesfahani, S., Kondyurin, A., Zreiqat, H. (2012). A facile method to in situ formation of hydroxyapatite single crystal architecture for enhanced osteoblast adhesion. Journal of Materials Chemistry, 22(36), 19081-19087. [More Information]
    • Lu, Z., Roohaniesfahani, S., Wang, G., Zreiqat, H. (2012). Bone biomimetic microenvironment induces osteogenic differentiation of adipose tissue-derived mesenchymal stem cells. Nanomedicine: Nanotechnology, Biology, and Medicine, 8(4), 507-515. [More Information]
    • Roohaniesfahani, S., Zreiqat, H. (2012). Ceramic Scaffolds, Current Issues and Future Trends. In M Ramalingam, Z Haidar, S Ramakrishna, H Kobayashi, Y Haikel (Eds.), Integrated Biomaterials in Tissue Engineering, (pp. 25-46). Salem, MA: Scrivener Publishing.
    • Roohaniesfahani, S., Lu, Z., Li, J., Ellis-Behnke, R., Kaplan, D., Zreiqat, H. (2012). Effect of self-assembled nanofibrous silk/polycaprolactone layer on the osteoconductivity and mechanical properties of biphasic calcium phosphate scaffolds. Acta Biomaterialia, 8(1), 302-312. [More Information]
    • Waterhouse, A., Wise, S., Yin, Y., Wu, B., James, B., Zreiqat, H., McKenzie, D., Bao, B., Weiss, A., Ng, M., Bilek, M. (2012). In vivo biocompatibility of a plasma-activated, coronary stent coating. Biomaterials, 33(32), 7984-7992. [More Information]
    • Roohaniesfahani, S., Wong, K., Lu, Z., Li, J., Zreiqat, H. (2012). Introducing Magnesium Silicate Based Scaffolds. International Forum of Biomedical Materials: Nanobiomaterials for Tissue Regeneration, China: Zhejiang University.
    • Roohaniesfahani, S., Wong, K., Lu, Z., Li, J., Zreiqat, H. (2012). Magnesium Silicate Scaffolds: a New Candidate Biomaterial for Bone Regeneration (ID:3072). 9th World Biomaterials Congress, China: World Biomaterials Congress.
    • Roohaniesfahani, S., Nouri-Khorasani, S., Lu, Z., Fathi, M., Razavi, M., Appleyard, R., Zreiqat, H. (2012). Modification of Porous Calcium Phosphate Surfaces with Different Geometries of Bioactive Glass Nanoparticles. Materials Science and Engineering C, 32(4), 830-839. [More Information]
    • Lu, W., McKenzie, D., Dunstan, C., Zreiqat, H., Bilek, M. (2012). Plasma Immersion Ion Implantation Treatment of Poly-ether Ether Ketone for the Immobilization of Biomolecules on Surfaces (ID: 836). International Forum of Biomedical Materials: Nanobiomaterials for Tissue Regeneration.
    • Wang, G., Lu, Z., Dwarte, D., Zreiqat, H. (2012). Porous scaffolds with tailored reactivity modulate in-vitro osteoblast responses. Materials Science and Engineering C, 32(7), 1818-1826. [More Information]
    • Roohaniesfahani, S., Dunstan, C., Davies, B., Pearce, S., Williams, R., Zreiqat, H. (2012). Repairing a critical-sized bone defect with highly porous modified and unmodified baghdadite scaffolds. Acta Biomaterialia, 8(11), 4162-4172. [More Information]
    • Lu, Z., Wang, G., Dunstan, C., Zreiqat, H. (2012). Short-Term Exposure to Tumor Necrosis Factor-Alpha Enables Human Osteoblasts to Direct Adipose Tissue-Derived Mesenchymal Stem Cells into Osteogenic Differentiation. Stem Cells and Development, 21(13), 2420-2429. [More Information]
    • Zhong, X., Lu, Z., Valtchev, P., Wei, H., Zreiqat, H., Dehghani, F. (2012). Surface modification of poly(propylene carbonate) by aminolysis and layer-by-layer assembly for enhanced cytocompatibility. Colloids And Surfaces B: Biointerfaces, 93(1), 75-84. [More Information]

    2011

    • Roohaniesfahani, S., Nouri-Khorasani, S., Lu, Z., Appleyard, R., Zreiqat, H. (2011). Effects of Bioactive Glass Nanoparticles on the Mechanical and Biological Behavior of Composite Coated Scaffolds. Acta Biomaterialia, 7(3), 1307-1318. [More Information]
    • Wang, G., Liu, X., Zreiqat, H., Ding, C. (2011). Enhanced effects of nano-scale topography on the bioactivity and osteoblast behaviors of micron rough ZrO2 coatings. Colloids And Surfaces B: Biointerfaces, 86(2), 267-274. [More Information]
    • Wang, G., Lu, Z., Liu, X., Zhou, X., Ding, C., Zreiqat, H. (2011). Nanostructured glass-ceramic coatings for orthopaedic applications. Journal of the Royal Society Interface, 8(61), 1192-1203. [More Information]
    • Roohaniesfahani, S., Lu, Z., Zreiqat, H. (2011). Novel, simple and reproducible method for preparation of composite hierarchal porous structure scaffolds. Materials Letters, 65(17-18), 2578-2581. [More Information]
    • Lu, Z., Roohaniesfahani, S., Kwok, P., Zreiqat, H. (2011). Osteoblasts on Rod Shaped Hydroxyapatite Nanoparticles Incorporated PCL Film Provide an Optimal Osteogenic Niche for Stem Cell Differentiation. Tissue Engineering. Part A, 17(11/12), 1651-1661. [More Information]

    2010

    • Lu, Z., Zreiqat, H. (2010). Beta-tricalcium phosphate exerts osteoconductivity through α2β1 integrin and down-stream MAPK/ERK signaling pathway. Biochemical and Biophysical Research Communications, 394(2), 323-329. [More Information]
    • Wu, C., Chang, J., Zreiqat, H. (2010). Engineered Ca-Si Based Ceramics for Skeletal Tissue Reconstruction. Materials Science Foundations (monograph series), 62, 122-149. [More Information]
    • Roohaniesfahani, S., Lu, Z., Li, J., Appleyard, R., Zreiqat, H. (2010). Enhancing Mechanical and Biological Behavior of Strontium-Doped Hardystonite Scaffolds with Nanocomposite Coating. TERMIS 2010, Orlando, Florida, United States of America.
    • Wang, G., Zreiqat, H. (2010). Functional Coatings or Films for Hard-Tissue Applications. Materials, 3(7), 3994-4050. [More Information]
    • Wang, G., Lu, Z., Liu, X., Zhou, X., Ding, C., Zreiqat, H. (2010). Nanostructured Biomedical Coatings for Orthopaedic Applications. 3rd Sydney University Tissue Engineering Network Symposium SuTEN 2010, Australia: University of Sydney.
    • Wang, G., Lu, Z., Liu, X., Zhou, X., Ding, C., Zreiqat, H. (2010). Nanostructured glass-ceramic coatings for orthopaedic applications. 15th Annual Scientific Meeting of the Australian and New Zealand Orthopaedic Research Society ANZORS 2010, Australia: Australian and New Zealand Orthopaedic Research Society.
    • Li, J., Roohaniesfahani, S., Lu, Z., Wang, G., Kaplan, D., Zreiqat, H. (2010). Novel Silk-Modified Strontium-Hardystonite Composite Scaffolds for Skeletal Regeneration. TERMIS - North America 2010 Conference on Tissue Engineering & Regenerative Medicine International Society, USA: Tissue Engineering & Regenerative Medicine International Society.
    • Wu, C., Zreiqat, H. (2010). Porous bioactive diopside (CaMgSi2O6) ceramic microspheres for drug delivery. Acta Biomaterialia, 6(3), 820-829. [More Information]
    • Wu, C., Ramaswamy, Y., Zreiqat, H. (2010). Porous diopside (CaMgSi2O6) scaffold: A promising bioactive material for bone tissue engineering. Acta Biomaterialia, 6(6), 2237-2245. [More Information]
    • Zreiqat, H., Yang, C., James, B., Duflou, J., Lowe, H. (2010). Probable endothelisation of bare metal stent struts extending from the left main coronary into the aorta. Journal of Thrombosis and Thrombolysis, 30(4), 500-501. [More Information]
    • Zreiqat, H., Belluoccio, D., Smith, M., Wilson, R., Rowley, L., Jones, K., Ramaswamy, Y., Vogl, T., Roth, J., Bateman, J., Little, C. (2010). S100A8 and S100A9 in experimental osteoarthritis. Arthritis Research & Therapy, 12(1), 1-13. [More Information]
    • Li, J., Roohaniesfahani, S., Lu, Z., Wang, G., Kaplan, D., Zreiqat, H. (2010). Silk-Modified Strontium-Hardystonite Scaffolds for Bone Tissue Engineering. 3rd Sydney University Tissue Engineering Network Symposium SuTEN 2010, Australia: University of Sydney.
    • Zreiqat, H., Ramaswamy, Y., Wu, C., Paschalidis, A., Lu, Z., James, B., Birke, O., McDonald, M., Little, D., Dunstan, C. (2010). The incorporation of strontium and zinc into a calcium-silicon ceramic for bone tissue engineering. Biomaterials, 31(12), 3175-3184. [More Information]
    • Roohaniesfahani, S., Nouri-Khorasani, S., Lu, Z., Appleyard, R., Zreiqat, H. (2010). The influence hydroxyapatite nanoparticle shape and size on the properties of biphasic calcium phosphate scaffolds coated with hydroxyapatite-PCL composites. Biomaterials, 31(21), 5498-5509. [More Information]
    • Lu, Z., Zreiqat, H. (2010). The Osteoconductivity of Biomaterials Is Regulated by Bone Morphogenetic Protein 2 Autocrine Loop Involving α2β1 Integrin and Mitogen-Activated Protein Kinase/Extracellular Related Kinase Signaling Pathways. Tissue Engineering. Part A, 16(10), 3075-3084. [More Information]

    2009

    • Wang, C., Karlis, G., Anderson, G., Dunstan, C., Carbone, A., Berger, G., Ploska, U., Zreiqat, H. (2009). Bone growth is enhanced by novel bioceramic coatings on Ti alloy implants. Journal of Biomedical Materials Research. Part A, 90A(2), 419-428. [More Information]
    • Ma, W., Ruys, A., Zreiqat, H. (2009). Diamond-like carbon (DLC) as a biocompatible coating in orthopaedic and cardiac medicine. In L Di Silvio (Eds.), Cellular Response to Biomaterials, (pp. 391-426). Cambridge: Woodhead Publishing Limited.
    • Schulze-Tanzil, G., Zreiqat, H., Sabat, R., Kohl, B., Halder, A., Muller, R., John, T. (2009). Interleukin-10 and articular cartilage: Experimental therapeutical approaches in cartilage disorders. Current Gene Therapy: the international journal for in-depth reviews on gene therapy, 9(4), 631-315. [More Information]
    • Ramaswamy, Y., Wu, C., Zreiqat, H. (2009). Orthopedic coating materials: Considerations and applications. Expert Review of Medical Devices, 6(4), 423-430. [More Information]
    • Wu, C., Ramaswamy, Y., Liu, X., Wang, G., Zreiqat, H. (2009). Plasma-sprayed CaTiSiO5 ceramic coating on Ti-6AI-4V with excellent bonding strength, stability and cellular bioactivity. Journal of the Royal Society Interface, 6(1), 159-168. [More Information]
    • Zreiqat, H., Wu, C., Ramaswamy, Y. (2009). Preparation and application of novel Baghdadite (Ca3ZrSi2O9) Scaffolds and coatings for skeletal tissue regeneration. Patent No. WO/2009/052583. Worldwide.
    • Ramaswamy, Y., Wu, C., Dunstan, C., Hewson, B., Eindorf, T., Anderson, G., Zreiqat, H. (2009). Sphene ceramics for orthopedic coating applications: An in vitro and in vivo study. Acta Biomaterialia, 5(8), 3192-3204. [More Information]
    • Wu, C., Ramaswamy, Y., Zhu, Y., Zheng, R., Appleyard, R., Howard, A., Zreiqat, H. (2009). The effect of mesoporous bioactive glass on the physiochemical, biological and drug-release properties of poly(DL-lactide-co-glycolide) films. Biomaterials, 30(12), 2199-2208. [More Information]

    2008

    • Zreiqat, H., James, B., Brieger, D., Kritharides, L., Lowe, H. (2008). Acute coronary stent thrombosis: Toward insights into possible mechanism using novel imaging methods. Thrombosis and Haemostasis, 99(5), 976-977. [More Information]
    • Ramaswamy, Y., Wu, C., Zhou, H., Zreiqat, H. (2008). Biological response of human bone cells to zinc-modified Ca-Si-based ceramics. Acta Biomaterialia, 4(5), 1487-1497. [More Information]
    • McMahon, A., Zreiqat, H., Lowe, H. (2008). Carotid artery stenting in the Zucker rat: a novel, potentially 'diabetes-specific' model of in-stent restenosis. Diabetes and Vascular Disease Research, 5(2), 145-146. [More Information]
    • Helary, G., Poussard, L., Zreiqat, H., Migonney, V. (2008). Functionalization of biomaterials for joint implant application. Bio-Medical Materials and Engineering, 18, 237-239. [More Information]
    • Wu, C., Ramaswamy, Y., Boughton, P., Zreiqat, H. (2008). Improvement of mechanical and biological properties of porous CaSiO3 scaffolds by poly(D,L-lactic acid) modification. Acta Biomaterialia, 4(2), 343-353. [More Information]
    • Wu, C., Ramaswamy, Y., Gail, D., Yang, W., Xiao, K., Zhang, L., Yin, Y., Zreiqat, H. (2008). Novel sphene coatings on Ti-6Al-4V for orthopaedic implants using sol-gel method. Acta Biomaterialia, 4, 569-576. [More Information]
    • Zhu, Y., Wu, C., Ramaswamy, Y., Kockrick, E., Simon, P., Kaskel, S., Zreiqat, H. (2008). Preparation, characterization and in vitro bioactivity of mesoporous bioactive glasses (MBGs) scaffolds for bone tissue engineering. Microporous and Mesoporous Materials, 112, 494-503.
    • Wu, C., Ramaswamy, Y., Chang, J., Woods, J., Chen, Y., Zreiqat, H. (2008). The Effect of Zn Contents on Phase Composition, Chemical Stability and Cellular Bioactivity in Zn-Ca-Si System Ceramics. Journal of Biomedical Materials Research. Part B: Applied Biomaterials, 87(2), 346-353. [More Information]
    • Ramaswamy, Y., Wu, C., Van Hummel, A., Combes, V., Grau, G., Zreiqat, H. (2008). The responses of osteoblasts, osteoclasts and endothelial cells to zirconium modified calcium-silicate-based ceramic. Biomaterials, 29(33), 4392-4402. [More Information]

    2007

    • Oberholzer, A., John, T., Kohl, B., Gust, T., Muller, R., La Face, D., Hutchins, B., Zreiqat, H., Ertel, W., Schulze-Tanzil, G. (2007). Adenoviral transduction is more efficient in alginate-derived chondrocytes than in monolayer chondrocytes. Cell and Tissue Research, 328(2), 383-390. [More Information]
    • Ma, W., Ruys, A., Mason, R., Martin, P., Bendavid, A., Liu, Z., Ionescu, M., Zreiqat, H. (2007). DLC coatings: Effects of physical and chemical properties on biological response. Biomaterials, 28(9), 1620-1628. [More Information]
    • Wu, C., Ramaswamy, Y., Soeparto, A., Zreiqat, H. (2007). Incorporation of titanium into calcium silicate improved their chemical stability and biological properties. Journal of Biomedical Materials Research. Part A, 86(2 (Online article 29 Oct 2007)), 402-410. [More Information]
    • John, T., Muller, R., Oberholzer, A., Zreiqat, H., Kohl, B., Ertel, W., Hostmann, A., Tschoeke, S., Schulze-Tanzil, G. (2007). Interleukin-10 modulates pro-apoptotic effects of TNF-alpha in human articular chondrocytes in vitro. Cytokine, 40(3), 226-234. [More Information]
    • Wu, C., Zreiqat, H. (2007). Preparation and Characteristics of Strontium Containing Bioactive CaSiO3 Ceramics. Key Engineering Materials, 330-332(I), 499-502.
    • Zreiqat, H., Howlett, C., Gronthos, S., Hume, D., Geczy, C. (2007). S100A8/S100A9 and their association with cartilage and bone. Journal of Molecular Histology, 38(5), 381-391. [More Information]
    • Wu, C., Ramaswamy, Y., Kwik, D., Zreiqat, H. (2007). The effect of strontium incorporation into CaSiO3 ceramics on their physical and biological properties. Biomaterials, 28(21), 3171-3181. [More Information]

    2006

    • Knabe, C., Kraska, B., Koch, C., Gross, U., Zreiqat, H., Stiller, M. (2006). A method for immunohistochemical detection of osteogenic markers in undecalcified bone sections. Biotechnic and Histochemistry, 81(1), 31-39.
    • Ma, W., Ruys, A., Mason, R., Martin, P., Bendavid, A., Liu, Z., Ionescu, M., Zreiqat, H. (2006). DLC coatings: Effects of physical and chemical properties on biological response. Biomaterials, 28(9), 1620-1628. [More Information]
    • Ramaswamy, W., Ben-Nissan, B., Roest, R., Haynes, D., Zreiqat, H. (2006). Human osteoclasts behaviour on sol-gel derived carbonate hydroxyapatite coatings on anodized titanium alloy substrates. Key Engineering Materials, 309-311, 709-712.
    • Ma, W., Ruys, A., Zreiqat, H., Mason, R., Ringer, S., Liu, Z., Keast, V., Martin, P., Bendavid, A. (2006). The Biocompatibility of Diamond-Like Carbon Nano Films. International Conference on Nanoscience and Nanotechnology 2006, Brisbane, Australia: (IEEE) Institute of Electrical and Electronics Engineers.

    2005

    • Ramaswamy, Y., Haynes, D., Berger, G., Gildenhaar, R., Lucas, H., Holding, C., Zreiqat, H. (2005). Bioceramics composition modulate resorption of human osteoclasts. Journal of Materials Science: Materials in Medicine, 16, 1199-1205. [More Information]
    • Zreiqat, H., Roest, R., Valenzuela, S., Milev, A., Ben-Nissan, B. (2005). Human Bone Derived Cell (HBDC) behaviour of sol-gel derived carbonate hydroxyapatite coatings on titanium alloy substrates. Key Engineering Materials, 284-286, 541-544.
    • McCormick, M., Rahimi, F., Bobryshev,, Y., Gaus, K., Zreiqat, H., Cai, H., Lord,, R., Geczy, C. (2005). S100A8 and S100A9 in Human Arterial Wall: implications for atherogenesis. Journal of Biological Chemistry, 280(50), 41521-41529.
    • Knabe, C., Stiller, M., Berger, G., Reif, D., Gildenhaar, R., Hewlett, C., Zreiqat, H. (2005). The effect of bioactive glass ceramics on the expression of bone-related genes and proteins in vitro. Clinical Oral Implants Research, 16(1), 119-127.
    • Zreiqat, H., Valenzuela, S., Ben-Nissan, B., Roest, R., Knabe, C., Radlanski, R., Renz, H., Evans, P. (2005). The effect of surface chemistry modification of titanium alloy on signalling pathways in human osteoblasts. Biomaterials, 26(36), 7579-7586. [More Information]

    2004

    • Knabe, C., Berger, G., Gildenhaar, R., Meyer, J., Hewlett, C., Markovic, B., Zreiqat, H. (2004). Effect of rapidly resorbable calcium phosphates and a calcium phosphate bone cement on the expression of bone-related genes and proteins in vitro. Journal of Biomedical Materials Research. Part A, 69A(1), 145-154.
    • Crotti, T., Smith, M., Findlay, D., Zreiqat, H., Ahern, M., Weedon, H., Hatzinikolous, G., Capone, M., Holding, C., Haynes, D. (2004). Factors regulating osteoclast formation in human tissues adjacent to peri-implant bone loss: expression of receptor activator NFκB, RANK ligand and osteoprotegerin. Biomaterials, 25(4), 565-573.
    • Wang, C., Duan, Y., Markovic, B., Barbara, J., Hewlett, C., Zhang, X., Zreiqat, H. (2004). Phenotypic expression of bone-related genes in osteoblasts grown on calcium phosphate ceramics with different phase compositions. Biomaterials, 25(13), 2507-2514. [More Information]
    • Wang, C., Duan, Y., Markovic, B., Barbara, J., Hewlett, C., Zhang, X., Zreiqat, H. (2004). Proliferation and bone-related gene expression of osteoblasts grown on hydroxyapatite ceramics sintered at different temperature. Biomaterials, 25(15), 2949-2956. [More Information]
    • Wang, C., Duan, Y., Markovic, B., Barbara, J., Hewlett, C., Zhang, X., Zreiqat, H. (2004). Quantitative Analysis of Osteoprotegerin and RANKL Expression in Osteoblast Grown on Different Calcium Phosphate Ceramics. Key Engineering Materials, 254-256, 713-716.
    • Haynes, D., Crotti, T., Zreiqat, H. (2004). Regulation of osteoclast activity in peri-implant tissues. Biomaterials, 25(20), 4877-4885. [More Information]
    • Knabe, C., Hewlett, C., Klar, F., Zreiqat, H. (2004). The effect of different titanium and hydroxyapatite-coated dental implant surfaces on phenotypic expression of human bone-derived cells. Journal of Biomedical Materials Research. Part A, 71A(1), 98-107. [More Information]
    • Zreiqat, H., Berger, G., Gildenhaar, R., Knabe, C. (2004). The Functional Expression of Human Bone-Derived Cells Grown on Rapidly Resorbable Calcium Phosphate Ceramics. Key Engineering Materials, 254-256, 1059-1062.
    • Knabe, C., Berger, G., Gildenhaar, R., Hewlett, C., Markovic, B., Zreiqat, H. (2004). The functional expression of human bone-derived cells grown on rapidly resorbable calcium phosphate ceramics. Biomaterials, 25, 335-344.
    • Knabe, C., Berger, G., Gildenhaar, R., Klar, F., Zreiqat, H. (2004). The modulation of osteogenesis in vitro by calcium titanium phosphate coatings. Biomaterials, 25(20), 4911-4919. [More Information]

    2003

    • Zreiqat, H., Ahu Akin, F., Hewlett, C., Markovic, B., Haynes, D., Lateef, S., Hanley, L. (2003). Differentiation of human bone-derived cells grown on GRGDSP-peptide bound titanium surfaces. Journal of Biomedical Materials Research. Part A, 64A(1), 105-113.
    • Zreiqat, H., Kumar, R., Markovic, B., Zicat, B., Hewlett, C. (2003). Macrophages at the skeletal tissue-device interface of loosened prosthetic devices express bone-related genes and their products. Journal of Biomedical Materials Research. Part A, 65A(1), 109-117.
    • Zreiqat, H., Crotti, T., Hewlett, C., Capone, M., Markovic, B., Haynes, D. (2003). Prosthetic particles modify the expression of bone-related proteins by human osteoblastic cells in vitro. Biomaterials, 24, 337-346.
    • Zreiqat, H., Hewlett, C., Zannettino, A., Evans, P., Knabe, C., Schulze-Tanzil, G., Shakibaei, G. (2003). Surface modification of bioceramics affect osteoblastic cells response. Key Engineering Materials, 240-242, 707-710.
    • Knabe, C., Hewlett, C., Markovic, B., Gildenhaar, R., Berger, G., Zreiqat, H. (2003). The functional expression of osteoblasts grown on rapidly resorbable calcium phosphates. Key Engineering Materials, 240-242(-), 679-682.

    2002

    • Zreiqat, H., Hewlett, C., Zannettino, A., Evans, P., Schulze-Tanzil, G., Knabe, C., Shakibaei, G. (2002). Mechanisms of magnesium-stimulated adhesion of osteoblastic cells to commonly used orthopaedic implants. Journal of Biomedical Materials Research. Part B: Applied Biomaterials, 62, 175-184.

    For support on your academic profile contact .