Table 1: Medicinal Chemistry

Table 1 lists units of study available to students in the Bachelor of Science and combined degrees. The units are available to students enrolled in other degrees in accordance with their degree resolutions.

Unit of study Credit points A: Assumed knowledge P: Prerequisites C: Corequisites N: Prohibition Session

Medicinal Chemistry

For a major in Medicinal Chemistry, the minimum requirement is 24 credit points comprising:
(i) PCOL3011/3911 and PCOL3012/3912; and
(ii) 12 credit points from senior Chemistry units of study.
Note that there are intermediate prerequisites for the core senior units of study. Junior and intermediate units of study should be selected to permit progression to the required senior units of study.
PCOL3011
Toxicology
6    P PCOL2011 and PCOL2012. For BMedSc: 18 credit points of BMED including BMED2401 or (BMED2801 and BMED2802)
N PCOL3911
Semester 1
PCOL3911
Toxicology (Advanced)
6    P Distinction average in PCOL2011 and PCOL2012. For BMedSc: Distinction average in 18 credit points of BMED units including BMED2401 or (BMED2801 and BMED2802).
N PCOL3011
Semester 1
PCOL3012
Drug Design and Development
6    P PCOL2011 and PCOL2012. For BMedSc: 18 credit points of BMED including BMED2401 or (BMED2801 and BMED2802).
N PCOL3912
Semester 1
PCOL3912
Drug Design and Development (Adv)
6    P Distinction average in PCOL2011 and PCOL2012. For BMedSc: Distinction average in 18 credit points of BMED units including BMED2401 or (BMED2801 and BMED2802).
N PCOL3012
Semester 1

Medicinal Chemistry

For a major in Medicinal Chemistry, the minimum requirement is 24 credit points comprising:
(i) PCOL3011/3911 and PCOL3012/3912; and
(ii) 12 credit points from senior Chemistry units of study.
Note that there are intermediate prerequisites for the core senior units of study. Junior and intermediate units of study should be selected to permit progression to the required senior units of study.
PCOL3011 Toxicology

Credit points: 6 Teacher/Coordinator: Dr Slade Matthews Session: Semester 1 Classes: Two 1 hour lectures and one 3 hour tutorial/practical per week. Prerequisites: PCOL2011 and PCOL2012. For BMedSc: 18 credit points of BMED including BMED2401 or (BMED2801 and BMED2802) Prohibitions: PCOL3911 Assessment: One 2 hour exam, tutorial presentations, assignments (100%) Associated degrees: B Med Sc, B Sc, UG Study Abroad Program.
This unit of study is designed to introduce students with a basic understanding of pharmacology to the discipline of toxicology. It considers the toxicology associated with therapeutic drugs (adverse drug reactions) and the associated issue of drug interactions. The pharmacogenetic basis of adverse reactions is also considered. The unit also considers aspects of environmental toxicology, particularly toxic reactions to environmental agents such as asbestos and pesticides, and its effects on different target organs (lung, liver, CNS). As a final consequence of exposure to toxins, the biology and causes of cancer are discussed. As part of the unit students are introduced to basic ideas about the collection and analysis of data from human and animal populations, both in the structured situation of clinical trials, forensic problems and in analysis of retrospective data.
Textbooks
Klaasen, Curtis D. Casarett and Doull's Toxicology: The Basic Science of Poisons. 7 ed. McGraw Hill. 2008.
PCOL3911 Toxicology (Advanced)

Credit points: 6 Teacher/Coordinator: Dr Slade Matthews Session: Semester 1 Classes: Two 1 hour lectures and one 3 hour tutorial/practical per week. Prerequisites: Distinction average in PCOL2011 and PCOL2012. For BMedSc: Distinction average in 18 credit points of BMED units including BMED2401 or (BMED2801 and BMED2802). Prohibitions: PCOL3011 Assessment: One 2 hour exam, tutorial presentations, assignments (100%) Associated degrees: B Med Sc, B Sc, UG Study Abroad Program.
This unit will consist of the lecture and practical components of PCOL3011. Students will be set special advanced assignments related to the material covered in core areas. These may also involve advanced practical work or detailed investigation of a theoretical problem.
Textbooks
Klaasen, Curtis D. Casarett and Doull's Toxicology: The Basic Science of Poisons. 7 ed. McGraw Hill. 2008.
PCOL3012 Drug Design and Development

Credit points: 6 Teacher/Coordinator: Dr Lenka Munoz Session: Semester 1 Classes: Two 1 hour lectures and one 3 hour tutorial/practical per week. Prerequisites: PCOL2011 and PCOL2012. For BMedSc: 18 credit points of BMED including BMED2401 or (BMED2801 and BMED2802). Prohibitions: PCOL3912 Assessment: One 2 hour exam, in class quizzes, assignments (100%) Associated degrees: B Med Sc, B Sc, UG Study Abroad Program.
This unit of study is designed to introduce students with a basic understanding of pharmacology to the field of medicinal chemistry associated with drug design and development. The course covers the fundamental aspects of drug discovery and development with reference to the essentials of chemistry and illustrates drug development with examples that include neuraminidase inhibitors and ACE inhibitors. The role of computers in drug design is emphasised by classwork and assignments on molecular modelling and structure-activity relationships. The course also extends to a section on the design of diverse pharmacological agents which include compounds for imaging by positron emission tomography (PET), and kinase inhibitors.
Textbooks
Patrick, Graham L. An Introduction to Medicinal Chemistry. 6th edition. Oxford University Press. 2013.
PCOL3912 Drug Design and Development (Adv)

Credit points: 6 Teacher/Coordinator: Dr Lenka Munoz Session: Semester 1 Classes: Two 1 hour lectures and one 3 hour tutorial/practical per week. Prerequisites: Distinction average in PCOL2011 and PCOL2012. For BMedSc: Distinction average in 18 credit points of BMED units including BMED2401 or (BMED2801 and BMED2802). Prohibitions: PCOL3012 Assessment: One 2 hour exam, in class quizzes, assignments (100%) Associated degrees: B Med Sc, B Sc, UG Study Abroad Program.
This unit will consist of the lecture and practical components of PCOL3012. Students will be set special advanced assignments related to the material covered in core areas. These may also involve advanced practical work or detailed investigation of a theoretical problem.
Textbooks
Patrick, Graham L. An Introduction to Medicinal Chemistry. 6th edition. Oxford University Press. 2013.