People_

Dr Cristian Leyton Moscoso

BMed USACH, GradDip Neuro PUC, PhD UNSW.

NHMRC/ARC Dementia Development Research Fellow
Senior Lecturer
Rural Clinical School (Northern Rivers)
Faculty of Medicine and Health

Phone

+610286276055

Email

cristian.leyton@sydney.edu.au

Details

Member of the Brain and Mind Centre

Member of the Charles Perkins Centre

Biographical details

In 2013, Dr Cristian Leyton completed his PhD at the University of New South Wales, Australia. In 2014, he was funded by the University of Sydney postdoctoral fellowship and appointed at the Faculty of Health Sciences. In 2016, he was awarded a Dementia Research Development Fellowship, a scheme co-funded by the Australian National Health and Medical Research Council and Australia Research Council. As a part of the international component, he conducted postdoctoral training at the Massachusetts General Hospital and Harvard Medical School, Boston, USA, between 2016 and 2017.

Research interests

Neurocognition of language
Dementia
Alzheimer's disease
Frontotemporal Dementias
Logopenic aphasia
Primary Progressive Aphasia
Neuroimaging
Biomarkers

Current projects

Disentangling language deficits in Alzheimer's disease

Associations

International Society for Frontotemporal Dementia
ARC Centre of Excellence in Cognition and its Disorders. Sydney, Australia.
American Academy of Neurology

Themes

Communication Sciences and Disorders

Publications

By Type

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Book Chapters

Leyton, C., Hodges, J. (2015). Differential diagnosis of primary progressive aphasia variants using the international criteria. In Lyndsey Nickels and Karen Croot (Eds.), Clinical Perspectives on Primary Progressive Aphasia (Brain, Behaviour and Cognition), (pp. 25-37). New York: Psychology Press.
Piguet, O., Leyton, C., Hodges, J. (2014). Frontotemporal dementias and related dementia syndromes. In Gideon Kaplan (Eds.), Geriatric Medicine: An Introduction, (pp. 108-124). Melbourne: IP Communications.

Journals

Landin-Romero, R., Kumfor, F., YS Lee, A., Leyton, C., Piguet, O. (2024). Clinical and cortical trajectories in non-fluent primary progressive aphasia and Alzheimer's disease: A role for emotion processing. Brain Research, 1829, 148777. [More Information]
Nguyen, T., Castro, N., Vitevitch, M., Harding, A., Teng, R., Arciuli, J., Leyton, C., Piguet, O., Ballard, K. (2022). Do age and language impairment affect speed of recognition for words with high and low closeness centrality within the phonological network? International Journal of Speech-Language Pathology. [More Information]
Kumfor, F., Liang, C., Hazelton, J., Leyton, C., Kaizik, C., Devenney, E., Connaughton, E., Langdon, R., Mioshi, E., Kwok, J., Dobson-Stone, C., Halliday, G., Piguet, O., Hodges, J., Landin-Romero, R. (2022). Examining the presence and nature of delusions in Alzheimer's disease and frontotemporal dementia syndromes. International Journal of Geriatric Psychiatry, 37(3), 1-12. [More Information]
Jansen, W., Janssen, O., Tijms, B., Vos, S., Ossenkoppele, R., Visser, P., Aarsland, D., Alcolea, D., Altomare, D., Von Arnim, C., Hodges, J., Leyton, C., et al (2022). Prevalence Estimates of Amyloid Abnormality Across the Alzheimer Disease Clinical Spectrum. JAMA Neurology, 79(3), 228-243. [More Information]
Foxe, D., Hu, A., Cheung, S., Ahmed, R., Cordato, N., Devenney, E., Hwang, Y., Halliday, G., Mueller, N., Leyton, C., Hodges, J., Burrell, J., Irish, M., Piguet, O. (2022). Utility of the Addenbrooke's Cognitive Examination III online calculator to differentiate the primary progressive aphasia variants. Brain Communications, 4(4), 1-15. [More Information]
Landin-Romero, R., Liang, C., Monroe, P., Higashiyama, Y., Leyton, C., Hodges, J., Piguet, O., Ballard, K. (2021). Brain changes underlying progression of speech motor programming impairment. Brain Communications, 3(3). [More Information]
Goldberg, Z., El-Omar, H., Foxe, D., Leyton, C., Ahmed, R., Piguet, O., Irish, M. (2021). Cognitive and neural mechanisms of social communication dysfunction in primary progressive aphasia. Brain Sciences, 11(12), 1600. [More Information]
Amadoru, S., Dore, V., McLean, C., Hinton, F., Shepherd, C., Halliday, G., Leyton, C., Yates, P., Hodges, J., Masters, C., et al (2020). Comparison of amyloid PET measured in Centiloid units with neuropathological findings in Alzheimer's disease. Alzheimer's Research and Therapy, 12(1), 22. [More Information]
Burrell, J., Foxe, D., Leyton, C., Piguet, O., Hodges, J. (2020). What to make of equivocal amyloid imaging results. Neurocase, 26(3), 137-146. [More Information]
Leyton, C., Landin-Romero, R., Liang, C., Burrell, J., Kumfor, F., Hodges, J., Piguet, O. (2019). Correlates of anomia in non-semantic variants of primary progressive aphasia converge over time. Cortex, 120, 201-211. [More Information]
Jafari, S., Modarresszadeh, A., Khatoonabadi, A., Hodges, J., Nakhostin Ansari, N., Leyton, C., Noroozian, M. (2018). Development, cross-cultural adaptation, and psychometric characteristics of the Persian progressive aphasia language scale in patients with primary progressive aphasia: A pilot study. Basic and Clinical Neuroscience, 9(1), 35-42. [More Information]
Leyton, C., Hillis, A. (2017). Affective prosody in frontotemporal dementia: the importance of “pitching it right”. Neurology, 89(7), 644-645. [More Information]
Tan, R., Kril, J., Yang, Y., Tom, N., Hodges, J., Villemagne, V., Rowe, C., Leyton, C., Kwok, J., Ittner, L., Halliday, G. (2017). Assessment of amyloid (beta) in pathologically confirmed frontotemporal dementia syndromes. Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, 9, 10-20. [More Information]
Midorikawa, A., Kumfor, F., Leyton, C., Foxe, D., Landin-Romero, R., Hodges, J., Piguet, O. (2017). Characterisation of "Positive" Behaviours in Primary Progressive Aphasias. Dementia and Geriatric Cognitive Disorders, 44(3-4), 119-128. [More Information]
Leyton, C., Hodges, J., Piguet, O., Ballard, K. (2017). Common and divergent neural correlates of anomia in amnestic and logopenic presentations of Alzheimer's disease. Cortex, 86, 45-54. [More Information]
Landin-Romero, R., Kumfor, F., Leyton, C., Irish, M., Hodges, J., Piguet, O. (2017). Disease-specific patterns of cortical and subcortical degeneration in a longitudinal study of Alzheimer's disease and behavioural-variant frontotemporal dementia. NeuroImage, 151, 72-80. [More Information]
Van Langenhove, T., Piquet, O., Burrell, J., Leyton, C., Foxe, D., Abela, M., Bartley, L., Kim, W., Jary, E., Huang, Y., Hodges, J., et al (2017). Predicting development of amyotrophic lateral sclerosis in frontotemporal dementia. Journal of Alzheimer's Disease, 58(1), 163-170. [More Information]
Midorikawa, A., Leyton, C., Foxe, D., Landin-Romero, R., Hodges, J., Piguet, O. (2016). All is Not Lost: Positive Behaviors in Alzheimer's Disease and Behavioral-Variant Frontotemporal Dementia with Disease Severity. Journal of Alzheimer's Disease, 54(2), 549-558. [More Information]
Van Langenhove, T., Leyton, C., Piguet, O., Hodges, J. (2016). Comparing Longitudinal Behavior Changes in the Primary Progressive Aphasias. Journal of Alzheimer's Disease, 53(3), 1033-1042. [More Information]
Tu, S., Leyton, C., Hodges, J., Piguet, O., Hornberger, M. (2016). Divergent Longitudinal Propagation of White Matter Degradation in Logopenic and Semantic Variants of Primary Progressive Aphasia. Journal of Alzheimer's Disease, 49(3), 853-861. [More Information]
Leyton, C., Cassidy, B., Villemagne, V., Jones, G., Kwok, J., Rowe, C., Ballard, K., Piquet, O., Hodges, J. (2016). Divergent Network Patterns of Amyloid-b Deposition in Logopenic and Amnestic Alzheimer's Disease Presentations. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 1(1), 24-31. [More Information]
Lillo, P., Leyton, C. (2016). How the diagnosis of frontotemporal dementia has resurged. Revista Medica Clinica Las Condes, 27(3), 309-318. [More Information]
O'Connor, C., Clemson, L., Hornberger, M., Leyton, C., Hodges, J., Piguet, O., Mioshi, E. (2016). Longitudinal change in everyday function and behavioral symptoms in frontotemporal dementia. Neurology: Clinical Practice, 6(5), 419-428. [More Information]
Schubert, S., Leyton, C., Hodges, J., Piguet, O. (2016). Longitudinal Memory Profiles in Behavioral-Variant Frontotemporal Dementia and Alzheimer's Disease. Journal of Alzheimer's Disease, 51(3), 775-782. [More Information]
Ramanan, S., Flanagan, E., Leyton, C., Villemagne, V., Rowe, C., Hodges, J., Hornberger, M. (2016). Non-Verbal Episodic Memory Deficits in Primary Progressive Aphasias are Highly Predictive of Underlying Amyloid Pathology. Journal of Alzheimer's Disease, 51(2), 367-373. [More Information]
Leyton, C., Ballard, K. (2016). Primary progressive aphasia: conceptual evolution and challenges. Neuroscience and Neuroeconomics, 5, 9-18. [More Information]
Hsieh, S., Leyton, C., Caga, J., Flanagan, E., Kaizik, C., O'Connor, C., Kiernan, M., Hodges, J., Piguet, O., Mioshi, E. (2016). The Evolution of Caregiver Burden in Frontotemporal Dementia with and without Amyotrophic Lateral Sclerosis. Journal of Alzheimer's Disease, 49(3), 875-885. [More Information]
Foxe, D., Leyton, C., Hodges, J., Burrell, J., Irish, M., Piguet, O. (2016). The neural correlates of auditory and visuospatial span in logopenic progressive aphasia and Alzheimer's disease. Cortex, 83, 39-50. [More Information]
Taswell, C., Villemagne, V., Yates, P., Shimada, H., Leyton, C., Ballard, K., Piguet, O., Burrell, J., Hodges, J., Rowe, C. (2015). 18F-FDG PET Improves Diagnosis in Patients with Focal-Onset Dementias. Journal of Nuclear Medicine, 56(10), 1547-1553. [More Information]
Leyton, C., Hodges, J., McLean, C., Kril, J., Piguet, O., Ballard, K. (2015). Is the logopenic-variant of primary progressive aphasia a unitary disorder? Cortex, 67, 122-133. [More Information]
Piguet, O., Leyton, C., Gleeson, L., Hoon, C., Hodges, J. (2015). Memory and Emotion Processing Performance Contributes to the Diagnosis of Non-Semantic Primary Progressive Aphasia Syndromes. Journal of Alzheimer's Disease, 44(2), 541-547. [More Information]
Ossenkoppele, R., Jansen, W., Rabinovici, G., Knol, D., van der Flier, W., van Berckel, B., Scheltens, P., Visser, P., Leyton, C. (2015). Prevalence of Amyloid PET Positivity in Dementia Syndromes: A Meta-analysis. JAMA, 313(19), 1939-1949. [More Information]
Kumfor, F., Sapey-Triomphe, L., Leyton, C., Burrell, J., Hodges, J., Piguet, O. (2014). Degradation of emotion processing ability in corticobasal syndrome and Alzheimer's disease. Brain, 137, 3061-3072. [More Information]
Leyton, C., Hodges, J. (2014). Differential diagnosis of primary progressive aphasia variants using the international criteria. Aphasiology, 28(8-9), 1-13. [More Information]
Ballard, K., Savage, S., Leyton, C., Vogel, A., Hornberger, M., Hodges, J. (2014). Logopenic and nonfluent variants of primary progressive aphasia are differentiated by acoustic measures of speech production. PloS One, 9(2), 1-14. [More Information]
Chare, L., Hodges, J., Leyton, C., McGinley, C., Tan, R., Kril, J., Halliday, G. (2014). New criteria for frontotemporal dementia syndromes: clinical and pathological diagnostic implications. Journal of Neurology, Neurosurgery and Psychiatry, 85(8), 866-871. [More Information]
Leyton, C., Ballard, K., Piguet, O., Hodges, J. (2014). Phonologic errors as a clinical marker of the logopenic variant of PPA. Neurology, 82(18), 1620-1627. [More Information]
Kumfor, F., Irish, M., Leyton, C., Miller, L., Lah, S., Devenney, E., Hodges, J., Piguet, O. (2014). Tracking the progression of social cognition in neurodegenerative disorders. Journal of Neurology, Neurosurgery and Psychiatry, 85(10), 1076-1083. [More Information]
Leyton, C., Savage, S., Irish, M., Schubert, S., Piguet, O., Ballard, K., Hodges, J. (2014). Verbal Repetition in Primary Progressive Aphasia and Alzheimer's Disease. Journal of Alzheimer's Disease, 41(2), 575-585. [More Information]
Leyton, C., Hsieh, S., Mioshi, E., Hodges, J. (2013). Cognitive decline in logopenic aphasia: More then losing words. Neurology, 80(10), 897-903. [More Information]
Leyton, C., Hodges, J. (2013). Towards a clearer definition of logopenic progressive aphasia. Current Neurology and Neuroscience Reports, 13(11), 396. [More Information]
Croot, K., Ballard, K., Leyton, C., Hodges, J. (2012). Apraxia of Speech and Phonological Errors in the Diagnosis of Nonfluent/Agrammatic and Logopenic Variants of Primary Progressive Aphasia. Journal of Speech, Language, and Hearing Research, 55(5), S1562-S1572. [More Information]
Hsieh, S., Hodges, J., Leyton, C., Mioshi, E. (2012). Longitudinal Changes in Primary Progressive Aphasias: Differences in Cognitive and Dementia Staging Measures. Dementia and Geriatric Cognitive Disorders, 34(1), 135-141. [More Information]
Leyton, C., Piguet, O., Savage, S., Burrell, J., Hodges, J. (2012). The Neural Basis of Logopenic Progressive Aphasia. Journal of Alzheimer's Disease, 32(4), 1051-1059. [More Information]
Jimenez-Cohl, P., Grekin, C., Leyton, C., Vargas, C., Villaseca, R. (2012). Thermal threshold: research study on small fiber dysfunction in distal diabetic polyneuropathy. Journal of Diabetes Science and Technology, 6(1), 177-183. [More Information]
Leyton, C., Villemagne, V., Savage, S., Pike, K., Ballard, K., Piguet, O., Burrell, J., Rowe, C., Hodges, J. (2011). Subtypes of progressive aphasia: Application of the international consensus criteria and validation using b-amyloid imaging. Brain, 134(10), 3030-3043. [More Information]
Leyton, C., Hornberger, M., Mioshi, E., Hodges, J. (2010). Application of Addenbrooke's Cognitive Examination to Diagnosis and Monitoring of Progressive Primary Aphasia. Dementia and Geriatric Cognitive Disorders, 29(6), 504-509. [More Information]
Leyton, C., Hodges, J. (2010). Frontotemporal dementias: recent advances and current controversies. Annals of Indian Academy of Neurology, 13(2), S74-S80. [More Information]

show 45 more

Conferences

GonzÃ¡lez Victoriano, R., Hornauer-Hughes, A., Leyton, C., Neumann Serra, S., Vera GonzÃ¡leza, R. (2015). Clinical characterisation of primary progressive aphasia cases using western aphasia battery (WAB-R). World Congress of Neurology, United Kingdom: Journal of the Neurological Sciences. [More Information]
Piguet, O., Schubert, S., Leyton, C., Hodges, J. (2015). Contrasting longitudinal changes in cognition in alzheimerâ€™s disease and behavioural-variant frontotemporal dementia. World Congress of Neurology, United Kingdom: Journal of the Neurological Sciences. [More Information]
Leyton, C., Cassidy, B., Jones, G., Villemagne, V., Ballard, K., Piguet, O., Hodges, J. (2015). Divergent complex network patterns of amyloid-b deposition between language and typical alzheimer's presentations. World Congress of Neurology, United Kingdom: Journal of the Neurological Sciences. [More Information]
Leyton, C., Cassidy, B., Villemagne, V., Jones, G., Kwok, J., Rowe, C., Ballard, K. (2015). Divergent network patterns of Amyloid-B deposition in language and amnestic AD presentations. Inter-University Neuroscience & Mental Health Conference, Sydney: N/A.
Leyton, C., Cassidy, B., Villemagne, V., Jones, G., Rowe, C., Ballard, K., Piguet, O., Hodges, J. (2015). Divergent network patterns of Amyloid-B deposition in language and typical Alzheimer's disease presentations. Asia & Pacific FTD & MND Meeting, Sydney: N/A.
Leyton, C., Piguet, O., Lam, B., Hodges, J., Ballard, K. (2014). Dissecting naming impairments in the logopenic variant of primary progressive aphasia. The 9th International Conference on Frontotemporal Dementias, United Kingdom.
Taswell, C., Villemagne, C., Yates, P., Shimada, H., Leyton, C., Ballard, K., Piguet, O., Burrell, J., Hodges, J., Rowe, C. (2014). FDG-PET improves diagnosis in patients presenting with focal onset variant of Alzheimerâ€™s disease. Society of Nuclear Medicine and Molecular Imaging Annual Meeting.
Leyton, C., Ballard, K., Piguet, O., Hodges, J. (2013). A specific clinical marker of logopenic aphasia. 41st Annual Tow Research Meeting, Sydney, Australia.
Ballard, K., Leyton, C., Vogel, A., Savage, S., Hodges, J. (2013). Logopenic & nonfluent primary progressive aphasia are reliably differentiated by acoustic measures of speech production. 2013 ASHA Convention, Chicago, USA.
Leyton, C., Ballard, K., Piguet, O., Hodges, J. (2013). Phonological errors as a specific clinical marker of logopenic aphasia. CCD Annual Workshop. Macquarie University.
Foxe, D., Irish, M., Leyton, C., Hodges, J., Piguet, O. (2013). Platform paper: The neural correlates of verbal and visuospatial span in logopenic progressive aphasia and Alzheimerâ€™s disease. Annual College of Clinical Neuropsychology Conference.
Kumfor, F., Irish, M., Leyton, C., Devenney, E., Hodges, J., Piguet, O. (2013). Social functioning decline distinguishes behavioural-variant frontotemporal dementia and Alzheimerâ€™s disease. 8th Annual Brain Sciences University of New South Wales (UNSW) Symposium: "The Interactive Brain: Translational Neuroscience".
Kumfor, F., Irish, M., Leyton, C., Devenney, E., Hodges, J., Piguet, O. (2013). Tracking the progression of emotional disturbance in neurodegenerative disorders. 19th Annual Australian Psychological Society (APS) College of Clinical Neuropsychologists Conference.
Leyton, C., Piguet, O., Savage, S., Burrell, J., Hodges, J. (2012). Neural correlates of impaired naming and repetition in Logopenic Progressive Aphasia. 8th International Conference on Frontotemporal Dementia, Manchester, UK.
Leyton, C., Savage, S., Piguet, O., Ballard, K., Pike, K., Villemagne, V., Jones, G., Rowe, C., Lillo, P., Hodges, J. (2010). Applicability and Predictability of the New PPA Consensus Criteria. 7th International Conference on Frontotemporal Dementia (FTD 2010), Indianapolis, USA: Springer Science+Business Media.
Leyton, C., Savage, S., Piguet, O., Ballard, K., Pike, K., Villemagne, V., Jones, G., Rowe, C., Burrell, J., Hodges, J. (2010). May Primary Progressive Aphasia be an atypical presentation of Alzheimerâ€™s disease? Brain Science UNSW Symposium. The Developing Brain â€“from Womb to Tomb.
Pike, K., Villemagne, V., Piguet, O., Ballard, K., Leyton, C., Jones, G., Rowe, C., Hodges, J. (2010). When is progressive aphasia due to Alzheimerâ€™s disease? A PiB-PET study. International Conference on Alzheimerâ€™s Disease.
Lillo, P., Savage, S., Hsieh, S., Mioshi, E., Leyton, C., Hodges, J. (2009). Behavioural changes and cognitive impairment in motor neurone disease. 19th World Congress of Neurology.

show 15 more

By Year

Expand all

2024

Landin-Romero, R., Kumfor, F., YS Lee, A., Leyton, C., Piguet, O. (2024). Clinical and cortical trajectories in non-fluent primary progressive aphasia and Alzheimer's disease: A role for emotion processing. Brain Research, 1829, 148777. [More Information]

2022

Nguyen, T., Castro, N., Vitevitch, M., Harding, A., Teng, R., Arciuli, J., Leyton, C., Piguet, O., Ballard, K. (2022). Do age and language impairment affect speed of recognition for words with high and low closeness centrality within the phonological network? International Journal of Speech-Language Pathology. [More Information]
Kumfor, F., Liang, C., Hazelton, J., Leyton, C., Kaizik, C., Devenney, E., Connaughton, E., Langdon, R., Mioshi, E., Kwok, J., Dobson-Stone, C., Halliday, G., Piguet, O., Hodges, J., Landin-Romero, R. (2022). Examining the presence and nature of delusions in Alzheimer's disease and frontotemporal dementia syndromes. International Journal of Geriatric Psychiatry, 37(3), 1-12. [More Information]
Jansen, W., Janssen, O., Tijms, B., Vos, S., Ossenkoppele, R., Visser, P., Aarsland, D., Alcolea, D., Altomare, D., Von Arnim, C., Hodges, J., Leyton, C., et al (2022). Prevalence Estimates of Amyloid Abnormality Across the Alzheimer Disease Clinical Spectrum. JAMA Neurology, 79(3), 228-243. [More Information]
Foxe, D., Hu, A., Cheung, S., Ahmed, R., Cordato, N., Devenney, E., Hwang, Y., Halliday, G., Mueller, N., Leyton, C., Hodges, J., Burrell, J., Irish, M., Piguet, O. (2022). Utility of the Addenbrooke's Cognitive Examination III online calculator to differentiate the primary progressive aphasia variants. Brain Communications, 4(4), 1-15. [More Information]

show 1 more

2021

Landin-Romero, R., Liang, C., Monroe, P., Higashiyama, Y., Leyton, C., Hodges, J., Piguet, O., Ballard, K. (2021). Brain changes underlying progression of speech motor programming impairment. Brain Communications, 3(3). [More Information]
Goldberg, Z., El-Omar, H., Foxe, D., Leyton, C., Ahmed, R., Piguet, O., Irish, M. (2021). Cognitive and neural mechanisms of social communication dysfunction in primary progressive aphasia. Brain Sciences, 11(12), 1600. [More Information]

2020

Amadoru, S., Dore, V., McLean, C., Hinton, F., Shepherd, C., Halliday, G., Leyton, C., Yates, P., Hodges, J., Masters, C., et al (2020). Comparison of amyloid PET measured in Centiloid units with neuropathological findings in Alzheimer's disease. Alzheimer's Research and Therapy, 12(1), 22. [More Information]
Burrell, J., Foxe, D., Leyton, C., Piguet, O., Hodges, J. (2020). What to make of equivocal amyloid imaging results. Neurocase, 26(3), 137-146. [More Information]

2019

Leyton, C., Landin-Romero, R., Liang, C., Burrell, J., Kumfor, F., Hodges, J., Piguet, O. (2019). Correlates of anomia in non-semantic variants of primary progressive aphasia converge over time. Cortex, 120, 201-211. [More Information]

2018

Jafari, S., Modarresszadeh, A., Khatoonabadi, A., Hodges, J., Nakhostin Ansari, N., Leyton, C., Noroozian, M. (2018). Development, cross-cultural adaptation, and psychometric characteristics of the Persian progressive aphasia language scale in patients with primary progressive aphasia: A pilot study. Basic and Clinical Neuroscience, 9(1), 35-42. [More Information]

2017

Leyton, C., Hillis, A. (2017). Affective prosody in frontotemporal dementia: the importance of “pitching it right”. Neurology, 89(7), 644-645. [More Information]
Tan, R., Kril, J., Yang, Y., Tom, N., Hodges, J., Villemagne, V., Rowe, C., Leyton, C., Kwok, J., Ittner, L., Halliday, G. (2017). Assessment of amyloid (beta) in pathologically confirmed frontotemporal dementia syndromes. Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, 9, 10-20. [More Information]
Midorikawa, A., Kumfor, F., Leyton, C., Foxe, D., Landin-Romero, R., Hodges, J., Piguet, O. (2017). Characterisation of "Positive" Behaviours in Primary Progressive Aphasias. Dementia and Geriatric Cognitive Disorders, 44(3-4), 119-128. [More Information]
Leyton, C., Hodges, J., Piguet, O., Ballard, K. (2017). Common and divergent neural correlates of anomia in amnestic and logopenic presentations of Alzheimer's disease. Cortex, 86, 45-54. [More Information]
Landin-Romero, R., Kumfor, F., Leyton, C., Irish, M., Hodges, J., Piguet, O. (2017). Disease-specific patterns of cortical and subcortical degeneration in a longitudinal study of Alzheimer's disease and behavioural-variant frontotemporal dementia. NeuroImage, 151, 72-80. [More Information]
Van Langenhove, T., Piquet, O., Burrell, J., Leyton, C., Foxe, D., Abela, M., Bartley, L., Kim, W., Jary, E., Huang, Y., Hodges, J., et al (2017). Predicting development of amyotrophic lateral sclerosis in frontotemporal dementia. Journal of Alzheimer's Disease, 58(1), 163-170. [More Information]

show 3 more

2016

Midorikawa, A., Leyton, C., Foxe, D., Landin-Romero, R., Hodges, J., Piguet, O. (2016). All is Not Lost: Positive Behaviors in Alzheimer's Disease and Behavioral-Variant Frontotemporal Dementia with Disease Severity. Journal of Alzheimer's Disease, 54(2), 549-558. [More Information]
Van Langenhove, T., Leyton, C., Piguet, O., Hodges, J. (2016). Comparing Longitudinal Behavior Changes in the Primary Progressive Aphasias. Journal of Alzheimer's Disease, 53(3), 1033-1042. [More Information]
Tu, S., Leyton, C., Hodges, J., Piguet, O., Hornberger, M. (2016). Divergent Longitudinal Propagation of White Matter Degradation in Logopenic and Semantic Variants of Primary Progressive Aphasia. Journal of Alzheimer's Disease, 49(3), 853-861. [More Information]
Leyton, C., Cassidy, B., Villemagne, V., Jones, G., Kwok, J., Rowe, C., Ballard, K., Piquet, O., Hodges, J. (2016). Divergent Network Patterns of Amyloid-b Deposition in Logopenic and Amnestic Alzheimer's Disease Presentations. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 1(1), 24-31. [More Information]
Lillo, P., Leyton, C. (2016). How the diagnosis of frontotemporal dementia has resurged. Revista Medica Clinica Las Condes, 27(3), 309-318. [More Information]
O'Connor, C., Clemson, L., Hornberger, M., Leyton, C., Hodges, J., Piguet, O., Mioshi, E. (2016). Longitudinal change in everyday function and behavioral symptoms in frontotemporal dementia. Neurology: Clinical Practice, 6(5), 419-428. [More Information]
Schubert, S., Leyton, C., Hodges, J., Piguet, O. (2016). Longitudinal Memory Profiles in Behavioral-Variant Frontotemporal Dementia and Alzheimer's Disease. Journal of Alzheimer's Disease, 51(3), 775-782. [More Information]
Ramanan, S., Flanagan, E., Leyton, C., Villemagne, V., Rowe, C., Hodges, J., Hornberger, M. (2016). Non-Verbal Episodic Memory Deficits in Primary Progressive Aphasias are Highly Predictive of Underlying Amyloid Pathology. Journal of Alzheimer's Disease, 51(2), 367-373. [More Information]
Leyton, C., Ballard, K. (2016). Primary progressive aphasia: conceptual evolution and challenges. Neuroscience and Neuroeconomics, 5, 9-18. [More Information]
Hsieh, S., Leyton, C., Caga, J., Flanagan, E., Kaizik, C., O'Connor, C., Kiernan, M., Hodges, J., Piguet, O., Mioshi, E. (2016). The Evolution of Caregiver Burden in Frontotemporal Dementia with and without Amyotrophic Lateral Sclerosis. Journal of Alzheimer's Disease, 49(3), 875-885. [More Information]
Foxe, D., Leyton, C., Hodges, J., Burrell, J., Irish, M., Piguet, O. (2016). The neural correlates of auditory and visuospatial span in logopenic progressive aphasia and Alzheimer's disease. Cortex, 83, 39-50. [More Information]

show 8 more

2015

Taswell, C., Villemagne, V., Yates, P., Shimada, H., Leyton, C., Ballard, K., Piguet, O., Burrell, J., Hodges, J., Rowe, C. (2015). 18F-FDG PET Improves Diagnosis in Patients with Focal-Onset Dementias. Journal of Nuclear Medicine, 56(10), 1547-1553. [More Information]
GonzÃ¡lez Victoriano, R., Hornauer-Hughes, A., Leyton, C., Neumann Serra, S., Vera GonzÃ¡leza, R. (2015). Clinical characterisation of primary progressive aphasia cases using western aphasia battery (WAB-R). World Congress of Neurology, United Kingdom: Journal of the Neurological Sciences. [More Information]
Piguet, O., Schubert, S., Leyton, C., Hodges, J. (2015). Contrasting longitudinal changes in cognition in alzheimerâ€™s disease and behavioural-variant frontotemporal dementia. World Congress of Neurology, United Kingdom: Journal of the Neurological Sciences. [More Information]
Leyton, C., Hodges, J. (2015). Differential diagnosis of primary progressive aphasia variants using the international criteria. In Lyndsey Nickels and Karen Croot (Eds.), Clinical Perspectives on Primary Progressive Aphasia (Brain, Behaviour and Cognition), (pp. 25-37). New York: Psychology Press.
Leyton, C., Cassidy, B., Jones, G., Villemagne, V., Ballard, K., Piguet, O., Hodges, J. (2015). Divergent complex network patterns of amyloid-b deposition between language and typical alzheimer's presentations. World Congress of Neurology, United Kingdom: Journal of the Neurological Sciences. [More Information]
Leyton, C., Cassidy, B., Villemagne, V., Jones, G., Kwok, J., Rowe, C., Ballard, K. (2015). Divergent network patterns of Amyloid-B deposition in language and amnestic AD presentations. Inter-University Neuroscience & Mental Health Conference, Sydney: N/A.
Leyton, C., Cassidy, B., Villemagne, V., Jones, G., Rowe, C., Ballard, K., Piguet, O., Hodges, J. (2015). Divergent network patterns of Amyloid-B deposition in language and typical Alzheimer's disease presentations. Asia & Pacific FTD & MND Meeting, Sydney: N/A.
Leyton, C., Hodges, J., McLean, C., Kril, J., Piguet, O., Ballard, K. (2015). Is the logopenic-variant of primary progressive aphasia a unitary disorder? Cortex, 67, 122-133. [More Information]
Piguet, O., Leyton, C., Gleeson, L., Hoon, C., Hodges, J. (2015). Memory and Emotion Processing Performance Contributes to the Diagnosis of Non-Semantic Primary Progressive Aphasia Syndromes. Journal of Alzheimer's Disease, 44(2), 541-547. [More Information]
Ossenkoppele, R., Jansen, W., Rabinovici, G., Knol, D., van der Flier, W., van Berckel, B., Scheltens, P., Visser, P., Leyton, C. (2015). Prevalence of Amyloid PET Positivity in Dementia Syndromes: A Meta-analysis. JAMA, 313(19), 1939-1949. [More Information]

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2014

Kumfor, F., Sapey-Triomphe, L., Leyton, C., Burrell, J., Hodges, J., Piguet, O. (2014). Degradation of emotion processing ability in corticobasal syndrome and Alzheimer's disease. Brain, 137, 3061-3072. [More Information]
Leyton, C., Hodges, J. (2014). Differential diagnosis of primary progressive aphasia variants using the international criteria. Aphasiology, 28(8-9), 1-13. [More Information]
Leyton, C., Piguet, O., Lam, B., Hodges, J., Ballard, K. (2014). Dissecting naming impairments in the logopenic variant of primary progressive aphasia. The 9th International Conference on Frontotemporal Dementias, United Kingdom.
Taswell, C., Villemagne, C., Yates, P., Shimada, H., Leyton, C., Ballard, K., Piguet, O., Burrell, J., Hodges, J., Rowe, C. (2014). FDG-PET improves diagnosis in patients presenting with focal onset variant of Alzheimerâ€™s disease. Society of Nuclear Medicine and Molecular Imaging Annual Meeting.
Piguet, O., Leyton, C., Hodges, J. (2014). Frontotemporal dementias and related dementia syndromes. In Gideon Kaplan (Eds.), Geriatric Medicine: An Introduction, (pp. 108-124). Melbourne: IP Communications.
Ballard, K., Savage, S., Leyton, C., Vogel, A., Hornberger, M., Hodges, J. (2014). Logopenic and nonfluent variants of primary progressive aphasia are differentiated by acoustic measures of speech production. PloS One, 9(2), 1-14. [More Information]
Chare, L., Hodges, J., Leyton, C., McGinley, C., Tan, R., Kril, J., Halliday, G. (2014). New criteria for frontotemporal dementia syndromes: clinical and pathological diagnostic implications. Journal of Neurology, Neurosurgery and Psychiatry, 85(8), 866-871. [More Information]
Leyton, C., Ballard, K., Piguet, O., Hodges, J. (2014). Phonologic errors as a clinical marker of the logopenic variant of PPA. Neurology, 82(18), 1620-1627. [More Information]
Kumfor, F., Irish, M., Leyton, C., Miller, L., Lah, S., Devenney, E., Hodges, J., Piguet, O. (2014). Tracking the progression of social cognition in neurodegenerative disorders. Journal of Neurology, Neurosurgery and Psychiatry, 85(10), 1076-1083. [More Information]
Leyton, C., Savage, S., Irish, M., Schubert, S., Piguet, O., Ballard, K., Hodges, J. (2014). Verbal Repetition in Primary Progressive Aphasia and Alzheimer's Disease. Journal of Alzheimer's Disease, 41(2), 575-585. [More Information]

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2013

Leyton, C., Ballard, K., Piguet, O., Hodges, J. (2013). A specific clinical marker of logopenic aphasia. 41st Annual Tow Research Meeting, Sydney, Australia.
Leyton, C., Hsieh, S., Mioshi, E., Hodges, J. (2013). Cognitive decline in logopenic aphasia: More then losing words. Neurology, 80(10), 897-903. [More Information]
Ballard, K., Leyton, C., Vogel, A., Savage, S., Hodges, J. (2013). Logopenic & nonfluent primary progressive aphasia are reliably differentiated by acoustic measures of speech production. 2013 ASHA Convention, Chicago, USA.
Leyton, C., Ballard, K., Piguet, O., Hodges, J. (2013). Phonological errors as a specific clinical marker of logopenic aphasia. CCD Annual Workshop. Macquarie University.
Foxe, D., Irish, M., Leyton, C., Hodges, J., Piguet, O. (2013). Platform paper: The neural correlates of verbal and visuospatial span in logopenic progressive aphasia and Alzheimerâ€™s disease. Annual College of Clinical Neuropsychology Conference.
Kumfor, F., Irish, M., Leyton, C., Devenney, E., Hodges, J., Piguet, O. (2013). Social functioning decline distinguishes behavioural-variant frontotemporal dementia and Alzheimerâ€™s disease. 8th Annual Brain Sciences University of New South Wales (UNSW) Symposium: "The Interactive Brain: Translational Neuroscience".
Leyton, C., Hodges, J. (2013). Towards a clearer definition of logopenic progressive aphasia. Current Neurology and Neuroscience Reports, 13(11), 396. [More Information]
Kumfor, F., Irish, M., Leyton, C., Devenney, E., Hodges, J., Piguet, O. (2013). Tracking the progression of emotional disturbance in neurodegenerative disorders. 19th Annual Australian Psychological Society (APS) College of Clinical Neuropsychologists Conference.

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2012

Croot, K., Ballard, K., Leyton, C., Hodges, J. (2012). Apraxia of Speech and Phonological Errors in the Diagnosis of Nonfluent/Agrammatic and Logopenic Variants of Primary Progressive Aphasia. Journal of Speech, Language, and Hearing Research, 55(5), S1562-S1572. [More Information]
Hsieh, S., Hodges, J., Leyton, C., Mioshi, E. (2012). Longitudinal Changes in Primary Progressive Aphasias: Differences in Cognitive and Dementia Staging Measures. Dementia and Geriatric Cognitive Disorders, 34(1), 135-141. [More Information]
Leyton, C., Piguet, O., Savage, S., Burrell, J., Hodges, J. (2012). Neural correlates of impaired naming and repetition in Logopenic Progressive Aphasia. 8th International Conference on Frontotemporal Dementia, Manchester, UK.
Leyton, C., Piguet, O., Savage, S., Burrell, J., Hodges, J. (2012). The Neural Basis of Logopenic Progressive Aphasia. Journal of Alzheimer's Disease, 32(4), 1051-1059. [More Information]
Jimenez-Cohl, P., Grekin, C., Leyton, C., Vargas, C., Villaseca, R. (2012). Thermal threshold: research study on small fiber dysfunction in distal diabetic polyneuropathy. Journal of Diabetes Science and Technology, 6(1), 177-183. [More Information]

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2011

Leyton, C., Villemagne, V., Savage, S., Pike, K., Ballard, K., Piguet, O., Burrell, J., Rowe, C., Hodges, J. (2011). Subtypes of progressive aphasia: Application of the international consensus criteria and validation using b-amyloid imaging. Brain, 134(10), 3030-3043. [More Information]

2010

Leyton, C., Savage, S., Piguet, O., Ballard, K., Pike, K., Villemagne, V., Jones, G., Rowe, C., Lillo, P., Hodges, J. (2010). Applicability and Predictability of the New PPA Consensus Criteria. 7th International Conference on Frontotemporal Dementia (FTD 2010), Indianapolis, USA: Springer Science+Business Media.
Leyton, C., Hornberger, M., Mioshi, E., Hodges, J. (2010). Application of Addenbrooke's Cognitive Examination to Diagnosis and Monitoring of Progressive Primary Aphasia. Dementia and Geriatric Cognitive Disorders, 29(6), 504-509. [More Information]
Leyton, C., Hodges, J. (2010). Frontotemporal dementias: recent advances and current controversies. Annals of Indian Academy of Neurology, 13(2), S74-S80. [More Information]
Leyton, C., Savage, S., Piguet, O., Ballard, K., Pike, K., Villemagne, V., Jones, G., Rowe, C., Burrell, J., Hodges, J. (2010). May Primary Progressive Aphasia be an atypical presentation of Alzheimerâ€™s disease? Brain Science UNSW Symposium. The Developing Brain â€“from Womb to Tomb.
Pike, K., Villemagne, V., Piguet, O., Ballard, K., Leyton, C., Jones, G., Rowe, C., Hodges, J. (2010). When is progressive aphasia due to Alzheimerâ€™s disease? A PiB-PET study. International Conference on Alzheimerâ€™s Disease.

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2009

Lillo, P., Savage, S., Hsieh, S., Mioshi, E., Leyton, C., Hodges, J. (2009). Behavioural changes and cognitive impairment in motor neurone disease. 19th World Congress of Neurology.

Selected Grants

2016

Disentangling aphasic syndromes in Alzheimers disease, Leyton C, National Health and Medical Research Council (NHMRC)/NHMRC-ARC Dementia Research Development Fellowships

2013

Differentiation and treatment for nonfluent variants of Primary Progressive Aphasia, Leyton C, Ballard K, DVC Research/Postdoctoral Research Fellowship Scheme