Miss Sonia Cheng

Map

Thesis work

Thesis title: An examination of physical activity and sedentary behaviour in chronic obstructive pulmonary disease

Supervisors: Sarah DENNIS , Zoe MCKEOUGH , Jennifer ALISON , Emmanuel STAMATAKIS

Thesis abstract:

Reducing sedentary time and increasing participation in light intensity physical activity may be a more realistic strategy for reducing cardiometabolic risk in people with chronic obstructive pulmonary disease (COPD) than only aiming to increase levels of moderate-vigorous intensity physical activity. Such an approach may also increase the confidence and willingness of people with COPD to engage in more intense activity, and may serve as an intermediate goal to increase uptake of pulmonary rehabilitation.

The first paper of this thesis examined the associations between total and type-specific physical activity with mortality in COPD. Our population-based cohort study demonstrated that participants who adhered to current physical activity recommendations had a lower risk of all-cause and cardiovascular disease mortality, but low levels of physical activity may still confer some mortality benefit in COPD. Dose-response associations with mortality risk were observed for walking and sport/exercise, but not domestic physical activity.

The second paper of this thesis examines the characteristics of physical activity and sedentary behaviour in Australian adults with COPD using a gold standard activity monitor (activPAL3 micro) and the Sedentary Behaviour Questionnaire. Previous studies in COPD have focused on quantifying physical activity rather than sedentary behaviour, and utilised 12-hour monitor wear protocols that likely underestimate total sedentary time. Physical activity and sedentary behaviour data will be collected at baseline from 70 participants with COPD enrolled in the randomised controlled trial (below), using a 24-hour wear protocol. This paper will also examine associations between sedentary behaviour and clinically relevant measures such as physical activity, lung function, functional exercise capacity, and health-related quality of life; and the validity, accuracy and precision of the Sedentary Behaviour Questionnaire for measuring total sedentary time in people with COPD. At present, baseline data has been collected for 67 of the 70 participants.

The third paper of this thesis aims to investigate the effectiveness and feasibility of a short-term behaviour change intervention to reduce sedentary time in COPD. The primary outcome measures are total sedentary time, sedentary time expressed as a percentage of total waking wear time, and usual bout duration (a measure of the pattern of accumulation of sedentary time); and feasibility of the intervention assessed by uptake and retention of participants, participant compliance, and adverse events. The secondary outcome measures are functional exercise capacity, health-related quality of life, psychosocial measures, and uptake and completion of pulmonary rehabilitation. At present, 63 of the 70 participants have completed the six-week intervention period.

Semi-structured interviews will also be conducted with a sample of participants who received the behaviour-change intervention to qualitatively explore participants’ experiences of the different components of the interventions, and barriers to reducing sedentary behaviour. The ‘Capability, Opportunity, Motivation and Behaviour’ model of behaviour change will be used as a theoretical frame to analyse the interview transcripts. Data will be collected until saturation is reached.

Selected grants

2017

  • The effectiveness and feasibility of a behaviour-change intervention to reduce sedentary time in people with Chronic Obstructive Pulmonary Disease (COPD): A pilot randomised controlled trial.; McKeough Z, Cheng S, Alison J, Stamatakis E, Dennis S; Physiotherapy Research Foundation/Seeding Grant.

Selected publications

Download citations: PDF RTF Endnote

Journals

  • Mijatovic, J., Capling, A., Cheng, S., Stamatakis, E., Louie, J., Cheung, N., Markovic, T., Ross, G., Senior, A., Brand-Miller, J., Flood, V. (2018). Associations of diet and physical activity with risk for gestational diabetes mellitus: A Systematic review and meta-analysis. Nutrients, 10(6). [More Information]
  • Cheng, S., McKeough, Z., Alison, J., Dennis, S., Hamer, M., Stamatakis, E. (2018). Associations of total and type-specific physical activity with mortality in chronic obstructive pulmonary disease: a population-based cohort study. BMC Public Health, 18(1). [More Information]
  • McKeough, Z., Cheng, S., Alison, J., Jenkins, C., Hamer, M., Stamatakis, E. (2018). Low leisure-based sitting time and being physically active were associated with reduced odds of death and diabetes in people with chronic obstructive pulmonary disease: a cohort study. Journal of Physiotherapy, 64(2), 114-120. [More Information]
  • Cheng, S., Alison, J., Dennis, S., Stamatakis, E., Spencer, L., McNamara, R., Sims, S., McKeough, Z. (2017). A behaviour change intervention to reduce sedentary time in people with chronic obstructive pulmonary disease: Protocol for a randomised controlled trial. Journal of Physiotherapy, 63(3), 182-182. [More Information]
  • Alison, J., Cheng, S., McKeough, Z. (2017). Pulmonary rehabilitation using minimal equipment for people with chronic obstructive pulmonary disease (COPD). Cochrane Database of Systematic Reviews, 2017 (12), 1-11. [More Information]

2018

  • Mijatovic, J., Capling, A., Cheng, S., Stamatakis, E., Louie, J., Cheung, N., Markovic, T., Ross, G., Senior, A., Brand-Miller, J., Flood, V. (2018). Associations of diet and physical activity with risk for gestational diabetes mellitus: A Systematic review and meta-analysis. Nutrients, 10(6). [More Information]
  • Cheng, S., McKeough, Z., Alison, J., Dennis, S., Hamer, M., Stamatakis, E. (2018). Associations of total and type-specific physical activity with mortality in chronic obstructive pulmonary disease: a population-based cohort study. BMC Public Health, 18(1). [More Information]
  • McKeough, Z., Cheng, S., Alison, J., Jenkins, C., Hamer, M., Stamatakis, E. (2018). Low leisure-based sitting time and being physically active were associated with reduced odds of death and diabetes in people with chronic obstructive pulmonary disease: a cohort study. Journal of Physiotherapy, 64(2), 114-120. [More Information]

2017

  • Cheng, S., Alison, J., Dennis, S., Stamatakis, E., Spencer, L., McNamara, R., Sims, S., McKeough, Z. (2017). A behaviour change intervention to reduce sedentary time in people with chronic obstructive pulmonary disease: Protocol for a randomised controlled trial. Journal of Physiotherapy, 63(3), 182-182. [More Information]
  • Alison, J., Cheng, S., McKeough, Z. (2017). Pulmonary rehabilitation using minimal equipment for people with chronic obstructive pulmonary disease (COPD). Cochrane Database of Systematic Reviews, 2017 (12), 1-11. [More Information]

For support on your academic profile contact .