%0 Journal Article
%~ IRMA
%A Boutin, Herve
%A Prenant, Christian
%A Maroy, Renaud
%A Galea, James
%A Greenhalgh, Andrew D.
%A Smigova, Alison
%A Cawthorne, Christopher
%A Julyan, Peter
%A Wilkinson, Shane
%A Banister, Samuel
%A Kassiou, Michael
%A et al, 
%T [(18)F]DPA-714: Direct comparison with [(11)C]PK11195 in a model of cerebral ischemia in rats
%B PLoS One
%D 2013
%@ 
%C United States
%I 
%V 8
%I Public Library of Science
%P e56441-1-e56441-9
%E 


%0 Journal Article
%~ IRMA
%A Wilkinson, Shane
%A Price, Jason
%A Kassiou, Michael
%T Improved accessibility to the desoxy analogues of delta(9)-tetrahydrocannabinol and cannabidiol
%B Tetrahedron Letters
%D 2013
%@ 
%C UK
%I 
%V 
%I Pergamon Elsevier
%P 
%E 


%0 Journal Article
%~ IRMA
%A Schollhorn-Peyronneau, Marie-Anne
%A Saba, W
%A Goutal, Sebastien
%A Damont, Annelaure
%A Dolle, Frederic
%A Kassiou, Michael
%A Bottlaender, Michael
%A Valette, Heric
%T Metabolism and quantification of [(18)F]DPA-714, a new TSPO positron emission tomography radioligand
%B Drug Metabolism and Disposition
%D 2013
%@ 
%C United States
%I 
%V 41
%I American Society for Pharmacology and Experimental Therapeutics
%P 122-131
%E 


%0 Journal Article
%~ IRMA
%A Kavanagh, Madeline
%A Doddareddy, Munikumar
%A Kassiou, Michael
%T The development of CNS-active LRRK2 inhibitors using property-directed optimisation
%B Bioorganic & Medicinal Chemistry Letters
%D 2013
%@ 
%C United Kingdom
%I 
%V 23
%I Pergamon Press
%P 3690-3696
%E 


%0 Journal Article
%~ IRMA
%A Banister, Samuel
%A Manoli, Miral
%A Kassiou, Michael
%T The development of radiotracers for imaging sigma receptors in the central nervous system (CNS) using positron emission tomography (PET)
%B Journal of Labelled Compounds and Radiopharmaceuticals
%D 2013
%@ 
%C United Kingdom
%I 
%V 56
%I John Wiley & Sons
%P 215-224
%E 


%0 Journal Article
%~ IRMA
%A Austin, Christopher
%A Kahlert, Jan
%A Kassiou, Michael
%A Rendina, Louis
%T The translocator protein (TSPO): A novel target for cancer chemotherapy
%B The International Journal of Biochemistry and Cell Biology
%D 2013
%@ 
%C United Kingdom
%I 
%V 45
%I Pergamon
%P 1212-1216
%E 


%0 Journal Article
%~ IRMA
%A Banister, Samuel
%A Rendina, Louis
%A Kassiou, Michael
%T 7-Azabicyclo[2.2.1]heptane as a scaffold for the development of selective
sigma-2 (r2) receptor ligands
%B Bioorganic and Medicinal Chemistry Letters: the tetrahedron journal for research at the interface of chemistry and biology
%D 2012
%@ 
%C United Kingdom
%I 
%V 22
%I Pergamon
%P 4059-4063
%E 


%0 Journal Article
%~ IRMA
%A Banister, Samuel
%A Rendina, Louis
%A Kassiou, Michael
%T 7-azabicyclo[2.2.1]heptane as a scaffold for the development of selective sigma-2 (sigma-2) receptor ligands
%B Bioorganic and Medicinal Chemistry Letters: the tetrahedron journal for research at the interface of chemistry and biology
%D 2012
%@ 
%C United Kingdom
%I 
%V 22
%I Pergamon
%P 4059-4063
%E 


%0 Journal Article
%~ IRMA
%A Banister, Samuel
%A Wilkinson, Shane
%A Hanani, Raphy
%A Reynolds, Aaron
%A Hibbs, David
%A Kassiou, Michael
%T A practical, multigram synthesis of the 2-(2-(4-alkoxyphenyl)-5,7-dimethylpy-razolo[1,5-a]pyrimidin-3-yl)acetamide (DPA) class of high affinity translocator protein (TSPO) ligands
%B Tetrahedron Letters
%D 2012
%@ 
%C UK
%I 
%V 53
%I Pergamon Elsevier
%P 3780-3783
%E 


%0 Journal Article
%~ IRMA
%A Banister, Samuel
%A Manoli, Miral
%A Doddareddy, Munikumar
%A Hibbs, David
%A Kassiou, Michael
%T A σ1 receptor pharmacophore derived from a series of N-substituted 4-azahexacyclo[5.4.1.0(2,6).0(3,10).0(5,9).0(8,11)]dodecan-3-ols (AHDS)
%B Bioorganic & Medicinal Chemistry Letters
%D 2012
%@ 
%C United Kingdom
%I 
%V 22
%I Pergamon Press
%P 6053-6058
%E 


%0 Journal Article
%~ IRMA
%A Beinat, Corinne
%A Banister, Samuel
%A Prehn, Saundra
%A Doddareddy, Munikumar
%A Hibbs, David
%A Sako, Michael
%A Collins (Chebib), Mary
%A Tran, Thao
%A Al-Muhtasib, Nour
%A Xiao, Yingxian
%A Kassiou, Michael
%T Consequences of linker length alteration of the alpha7 nicotinic acetylcholine receptor (nAChR) agonist, SEN12333
%B Bioorganic and Medicinal Chemistry Letters: the tetrahedron journal for research at the interface of chemistry and biology
%D 2012
%@ 
%C United Kingdom
%I 
%V 22
%I Pergamon
%P 2380-2384
%E 


%0 Journal Article
%~ IRMA
%A Leaver, Katherine
%A Reynolds, Aaron
%A Bodard, Sylvie
%A Guilloteau, Denis
%A Chalon, Sylvie
%A Kassiou, Michael
%T Effects of Translocator Protein (18 kDa) Ligands on Microglial Activation and Neuronal Death in the Quinolinic-Acid-Injected Rat Striatum
%B ACS Chemical Neuroscience
%D 2012
%@ 
%C United States
%I 
%V 3
%I American Chemical Society
%P 114-119
%E 


%0 Journal Article
%~ IRMA
%A Scarf, Alana
%A Luus, Christopher
%A Da Pozzo, Eleonora
%A Selleri, Silvia
%A Guarino, C.
%A Martini, Claudia
%A Ittner, Lars
%A Kassiou, Michael
%T Evidence for complex binding profiles and species differences at the translocator protein (TSPO) (18 kDa)
%B Current Molecular Medicine
%D 2012
%@ 
%C Netherlands
%I 
%V 12
%I Bentham Science Publishers Ltd.
%P 488-493
%E 


%0 Journal Article
%~ IRMA
%A Moussa, Iman
%A Banister, Samuel
%A Manoli, Miral
%A Doddareddy, Munikumar
%A Cui, Jinquan
%A Mach, Robert H.
%A Kassiou, Michael
%T Exploration of ring size in a series of cyclic vicinal diamines with sigma(1) receptor-affinity
%B Bioorganic & Medicinal Chemistry Letters
%D 2012
%@ 
%C United Kingdom
%I 
%V 22
%I Pergamon Press
%P 5493-5497
%E 


%0 Journal Article
%~ IRMA
%A Gilmore, Andrew
%A Heblinski, Marika
%A Reynolds, Aaron
%A Kassiou, Michael
%A Connor, Mark
%T Inhibition of human recombinant T-type calcium channels by N-arachidonoyl 5-HT
%B British Journal of Pharmacology
%D 2012
%@ 
%C United Kingdom
%I 
%V 167
%I John Wiley & Sons
%P 1076-1088
%E 


%0 Journal Article
%~ IRMA
%A Arlicot, Nicholas
%A Vercouillie, Johnny
%A Ribeiro, M.J.
%A Tauber, C.
%A Venel, Yann
%A Baulieu, J.L.
%A Maia, Serge
%A Corcia, P.
%A Stabin, Michael
%A Reynolds, Aaron
%A Kassiou, Michael
%A et al, 
%T Initial evaluation in healthy humans of [18F]DPA-714, a potential PET biomarker for neuroinflammation
%B Nuclear Medicine and Biology
%D 2012
%@ 
%C United States
%I 
%V 39
%I Elsevier
%P 570-578
%E 


%0 Journal Article
%~ IRMA
%A Scarf, Alana
%A Aumann, Kylee
%A Kassiou, Michael
%T Is there any correlation between binding and functional effects at the translocator protein (TSPO) (18 kDa)?
%B Current Molecular Medicine
%D 2012
%@ 
%C Netherlands
%I 
%V 12
%I Bentham Science Publishers Ltd.
%P 387-397
%E 


%0 Journal Article
%~ IRMA
%A Corcia, Philippe
%A Tauber, Clovis
%A Vercoullie, Johnny
%A Arlicot, Nicholas
%A Prunier, Caroline
%A Praline, Julien
%A Nicolas, Guillaume
%A Venel, Yann
%A Hommet, Caroline
%A Baulieu, J.L.
%A Kassiou, Michael
%A et al, 
%T Molecular imaging of microglial activation in amyotrophic lateral sclerosis
%B PLoS One
%D 2012
%@ 
%C United States
%I 
%V 7
%I Public Library of Science
%P 1-7
%E 


%0 Journal Article
%~ IRMA
%A Endres, Christopher
%A Coughlin, Jennifer M.
%A Gage, Kenneth L.
%A Watkins, Crystal
%A Kassiou, Michael
%A Pomper, Martin G
%T Radiation dosimetry and biodistribution of the TSPO ligand (11)C-DPA-713 in humans
%B The Journal of Nuclear Medicine
%D 2012
%@ 
%C United States
%I 
%V 53
%I Society of Nuclear Medicine
%P 330-335
%E 


%0 Journal Article
%~ IRMA
%A Gosling, Joshua I.
%A Baker, Stephen P.
%A Haynes, John M.
%A Kassiou, Michael
%A Pouton, Colin W.
%A Warfe, Lyndon
%A White, Paul J.
%A Scammells, Peter J.
%T Synthesis and Biological Evaluation of Adenosines with
Heterobicyclic and Polycyclic N6-Substituents as Adenosine A1 Receptor Agonists
%B ChemMedChem: chemistry enabling drug discovery
%D 2012
%@ 
%C Germany
%I 
%V 7
%I Wiley - V C H Verlag GmbH & Co. KGaA
%P 1191-1201
%E 


%0 Conference Proceedings
%~ IRMA
%A Fulham, Michael
%A Kassiou, Michael
%A Greguric, Ivan
%A Thomson, Sally
%A Eberl, Stefan
%A Tiam, Pham
%A Mattner, Filomena
%A Henderson, David
%A Fulton, Roger
%A Katsifis, Andrew
%A et al, 
%T Synthesis and in vivo evaluation of arylalkyl 4-benzyl piperidines as radioligands for sigma receptors
%B 16th International Symposium on Radiopharmaceutical Chemistry
%D 2012
%@ 
%C United Kingdom
%I 
%V 
%I Wiley
%P 
%E 


%0 Journal Article
%~ IRMA
%A Hicks, Callum
%A Jorgensen, William
%A Brown, C
%A Fardell, Joanna
%A Koehbach, J.
%A Gruber, C.W.
%A Kassiou, Michael
%A Hunt, Glenn
%A McGregor, Iain
%T The Nonpeptide Oxytocin Receptor Agonist WAY 267,464: Receptor-Binding Profile, Prosocial Effects and Distribution of c-Fos Expression in Adolescent Rats
%B Journal of Neuroendocrinology
%D 2012
%@ 
%C United Kingdom
%I 
%V 24
%I Wiley-Blackwell Publishing
%P 1012-1029
%E 


%0 Journal Article
%~ IRMA
%A Banister, Samuel
%A Kassiou, Michael
%T The Therapeutic Potential of Sigma (sigma) Receptors for the Treatment of Central Nervous System Diseases: Evaluation of the Evidence
%B Current Pharmaceutical Design
%D 2012
%@ 
%C Netherlands
%I 
%V 18
%I Bentham Science Publishers Ltd.
%P 884-901
%E 


%0 Journal Article
%~ IRMA
%A Dolle, Frederic
%A Kuhnast, B
%A Damont, Annelaure
%A van Camp, N
%A Kassiou, Michael
%A Tavitian, Bertrand
%A Boisgard, R
%T [18F]DPA-716 as a candidate for imaging the TSPO 18 kDa with PET: Radiosynthesis and comparative evaluation ([11C]DPA-713/[18F]DPA-714) in a rat model of neuroinflammation
%B Journal of Labelled Compounds and Radiopharmaceuticals
%D 2011
%@ 
%C United Kingdom
%I 
%V 54
%I John Wiley & Sons
%P S275-S275
%E 


%0 Journal Article
%~ IRMA
%A Vercouillie, Johnny
%A Ribeiro, M.J.
%A Tauber, C.
%A Venel, Y.
%A Baulieu, J.L.
%A Maia, S.
%A Reynolds, Aaron
%A Kassiou, Michael
%A Guilloteau, Denis
%A Corcia, P.
%T Biodistribution of the TSPO radioligand (18)F-DPA-714 in healthy volunteers
%B Journal of Labelled Compounds and Radiopharmaceuticals
%D 2011
%@ 
%C United Kingdom
%I 
%V 54
%I John Wiley & Sons
%P S255-S255
%E 


%0 Journal Article
%~ IRMA
%A Issa, Fatiah
%A Kassiou, Michael
%A Rendina, Louis
%T Boron in drug discovery: Carboranes as unique pharmacophores in biologically active compounds
%B Chemical Reviews
%D 2011
%@ 
%C United States
%I 
%V 111
%I American Chemical Society
%P 5701-5722
%E 


%0 Journal Article
%~ IRMA
%A Drake, Caroline
%A Boutin, Herve
%A Jones, Matthew S.
%A Denes, Adam
%A McColl, Barry W.
%A Selvarajah, Johann R.
%A Hulme, Sharon
%A Georgiou, Rachel F.
%A Hinz, Rainer
%A Gerhard, Alexander
%A Kassiou, Michael
%A et al, 
%T Brain inflammation is induced by co-morbidities and risk factors for stroke
%B Brain, Behavior, and Immunity
%D 2011
%@ 
%C United States
%I 
%V 25
%I Academic Press Elsevier
%P 1113-1122
%E 


%0 Journal Article
%~ IRMA
%A Dolle, Frederic
%A Le Helleix, Stephane
%A Schollhorn-Peyronneau, Marie-Anne
%A Saba, W
%A Banister, Samuel
%A Tournier, Nicholas
%A Valette, Heric
%A Kassiou, Michael
%T Carbon-11-labelling of a novel, trishomocubane-derived, high affinity and selectivity DAT ligand
%B Journal of Labelled Compounds and Radiopharmaceuticals
%D 2011
%@ 
%C United Kingdom
%I 
%V 54
%I John Wiley & Sons
%P S276-S276
%E 


%0 Journal Article
%~ IRMA
%A Moussa, Iman
%A Banister, Samuel
%A Akladios, Fady
%A Chua, Sook
%A Kassiou, Michael
%T Effects of linker elongation in a series of N-(2-benzofuranylmethyl)-N'-(methoxyphenylalkyl)piperazine sigma(1) receptor ligands
%B Bioorganic and Medicinal Chemistry Letters: the tetrahedron journal for research at the interface of chemistry and biology
%D 2011
%@ 
%C United Kingdom
%I 
%V 21
%I Pergamon
%P 5707-5710
%E 


%0 Journal Article
%~ IRMA
%A Banister, Samuel
%A Moussa, Iman
%A Jorgensen, William
%A Chua, Sook
%A Kassiou, Michael
%T Molecular hybridization of 4-azahexacyclo[5.4.1.0(2,6).0(3,10).0(5,9).0(8,11)]dodecane-3-ol with sigma (σ) receptor ligands modulates off-target activity and subtype selectivity
%B Bioorganic and Medicinal Chemistry Letters: the tetrahedron journal for research at the interface of chemistry and biology
%D 2011
%@ 
%C United Kingdom
%I 
%V 21
%I Pergamon
%P 3622-3626
%E 


%0 Journal Article
%~ IRMA
%A Banister, Samuel
%A Yoo, David
%A Chua, Sook
%A Cui, Jinquan
%A Mach, Robert H.
%A Kassiou, Michael
%T N-arylalkyl-2-azaadamantanes as cage-expanded polycarbocyclic sigma (sigma) receptor ligands
%B Bioorganic and Medicinal Chemistry Letters: the tetrahedron journal for research at the interface of chemistry and biology
%D 2011
%@ 
%C United Kingdom
%I 
%V 21
%I Pergamon
%P 5289-5292
%E 


%0 Journal Article
%~ IRMA
%A Ribeiro, M.J.
%A Vercouillie, Johnny
%A Tauber, C.
%A Venel, Y.
%A Baulieu, J.L.
%A Maia, S.
%A Reynolds, Aaron
%A Kassiou, Michael
%A Guilloteau, Denis
%A Corcia, P.
%T P-167 The potential interest of the PET radioligand (18)F-DPA-714 in neuroinflammation
%B Journal of Labelled Compounds and Radiopharmaceuticals
%D 2011
%@ 
%C United Kingdom
%I 
%V 54
%I John Wiley & Sons
%P S256-S256
%E 


%0 Journal Article
%~ IRMA
%A Martin, Abraham
%A Boisgard, R
%A Kassiou, Michael
%A Dolle, Frederic
%A Tavitian, Bertrand
%T Reduced PBR/TSPO Expression After Minocycline Treatment in a Rat Model of Focal Cerebral Ischemia:  A PET Study Using [(18)F]DPA-714
%B Molecular Imaging and Biology
%D 2011
%@ 
%C United States
%I 
%V 13
%I Springer
%P 10-15
%E 


%0 Journal Article
%~ IRMA
%A Boucher, Aurelie
%A Arnold, Jonathon
%A Hunt, Glenn
%A Spiro, Adena
%A Spencer, Jarrah
%A Brown, C
%A McGregor, Iain
%A Bennett, Maxwell
%A Kassiou, Michael
%T Resilience and Reduced C-FOS Expression in P2X7 Receptor Knockout Mice Exposed to Repeated Forced Swim Test
%B Neuroscience
%D 2011
%@ 
%C United Kingdom
%I 
%V 189
%I Pergamon
%P 170-177
%E 


%0 Journal Article
%~ IRMA
%A Crossley, Ellen
%A Issa, Fatiah
%A Scarf, Alana
%A Kassiou, Michael
%A Rendina, Louis
%T Synthesis and cellular uptake of boron-rich pyrazolopyrimidines: exploitation of the translocator protein for the efficient delivery of boron into human glioma cells
%B Chemical Communications
%D 2011
%@ 
%C Cambridge, UK
%I 
%V 47
%I Royal Society of Chemistry
%P 12179-12181
%E 


%0 Journal Article
%~ IRMA
%A Moussa, Iman
%A Banister, Samuel
%A Giboureau, Nicolas
%A Meikle, Steven
%A Kassiou, Michael
%T Synthesis and in vivo evaluation of [18F]N-(2-benzofuranylmethyl)-N'-[4-(2-fluoroethoxy)benzyl]piperazine, a novel σ1 receptor PET imaging agent
%B Bioorganic and Medicinal Chemistry Letters: the tetrahedron journal for research at the interface of chemistry and biology
%D 2011
%@ 
%C United Kingdom
%I 
%V 21
%I Pergamon
%P 6820-6823
%E 


%0 Journal Article
%~ IRMA
%A Damont, Annelaure
%A Boisgard, R
%A Kuhnast, Bertrand
%A Lemee, Frederic
%A Raggiri, Guillaume
%A Scarf, Alana
%A Da Pozzo, Eleonora
%A Selleri, Silvia
%A Martini, Claudia
%A Tavitian, Bertrand
%A Kassiou, Michael
%A et al, 
%T Synthesis of 6-[(18)F]fluoro-PBR28, a novel radiotracer for imaging the TSPO 18 kDa with PET
%B Bioorganic and Medicinal Chemistry Letters: the tetrahedron journal for research at the interface of chemistry and biology
%D 2011
%@ 
%C United Kingdom
%I 
%V 21
%I Pergamon
%P 4819-4822
%E 


%0 Journal Article
%~ IRMA
%A Scarf, Alana
%A Kassiou, Michael
%T The translocator protein
%B The Journal of Nuclear Medicine
%D 2011
%@ 
%C United States
%I 
%V 52
%I Society of Nuclear Medicine
%P 677-680
%E 


%0 Journal Article
%~ IRMA
%A Banister, Samuel
%A Moussa, Iman
%A Beinat, Corinne
%A Reynolds, Aaron
%A Schiavini, Paolo
%A Jorgensen, William
%A Kassiou, Michael
%T Trishomocubane as a Scaffold for the Development of Selective Dopamine Transporter (DAT) Ligands
%B Bioorganic and Medicinal Chemistry Letters: the tetrahedron journal for research at the interface of chemistry and biology
%D 2011
%@ 
%C United Kingdom
%I 
%V 21
%I Pergamon
%P 38-41
%E 


%0 Journal Article
%~ IRMA
%A Banister, Samuel
%A Clegg, Jack
%A Hanani, Raphy
%A Kassiou, Michael
%T 11-{[2-(3-fluorophenyl)ethyl](methyl)-amino}pentacyclo[5.4.0.0(2,6).0(3,10).0(5,9)]-undecan-8-one
%B Acta Crystallographica. Section E: Structure Reports Online
%D 2010
%@ 
%C Denmark
%I 
%V 66
%I Wiley-Blackwell Publishing
%P o2693-o2693
%E 


%0 Patents Applied Measures
%~ IRMA
%A Kassiou, Michael
%A James, Michelle
%T 2-Arylpyrazolo[L,5-a]Pyrimidin-3-yl Acetamide Deriv As Ligands For Translocator Protein (18Kda) (SA)
%B 
%D 2010
%@ 2008/10473
%C South Africa
%I 
%V 
%I Patent: 2-Arylpyrazolo[L,5-a]Pyrimidin-3-yl Acetamide Deriv As Ligands For Translocator Protein
%P 
%E 


%0 Journal Article
%~ IRMA
%A Naidoo (Naidoo-Variawa), Sheruna
%A Lehnert, Wencke
%A Kassiou, Michael
%A Banati, Richard
%A Meikle, Steven
%T Attenuation correction for the large non-human primate brain imaging using microPET
%B Physics in Medicine and Biology
%D 2010
%@ 
%C United Kingdom
%I 
%V 55
%I Institute of Physics Publishing
%P 2351-2363
%E 


%0 Journal Article
%~ IRMA
%A Morrison, Daniel
%A Issa, Fatiah
%A Bhadbhade, Mohan
%A Groebler, Ludwig
%A Witting, Paul
%A Kassiou, Michael
%A Rutledge, Peter
%A Rendina, Louis
%T Boronated phosphonium salts containing arylboronic acid, closo-carborane, or nido-carborane: synthesis, X-ray diffraction, in vitro cytotoxicity, and cellular uptake
%B Journal of Biological Inorganic Chemistry
%D 2010
%@ 
%C USA
%I 
%V 15
%I Springer
%P 1305-1318
%E 


%0 Journal Article
%~ IRMA
%A Moussa, Iman
%A Banister, Samuel
%A Beinat, Corinne
%A Giboureau, Nicolas
%A Reynolds, Aaron
%A Kassiou, Michael
%T Design, synthesis, and structure-affinity relationships of regioisomeric N-benzyl alkyl ether piperazine derivatives as sigma-1 receptor ligands
%B Journal of Medicinal Chemistry
%D 2010
%@ 
%C United States
%I 
%V 53
%I American Chemical Society
%P 6228-6239
%E 


%0 Journal Article
%~ IRMA
%A Giboureau, Nicolas
%A Aumann, Kylee
%A Beinat, Corinne
%A Kassiou, Michael
%T Development of vesicular acetylcholine transporter ligands: Molecular probes for Alzheimer's disease
%B Current Bioactive Compounds
%D 2010
%@ 
%C The Netherlands
%I 
%V 6
%I Bentham Science Publishers Ltd.
%P 129-155
%E 


%0 Journal Article
%~ IRMA
%A Abraham, Martin
%A Boisgard, R
%A Theze, Benoit
%A Van Camp, Nadja
%A Kuhnast, Bertrand
%A Damont, Annelaure
%A Kassiou, Michael
%A Dolle, Frederic
%A Tavitian, Bertrand
%T Evaluation of the PBR/TSPO radioloigand [18F]DPA-714 in a rat model of focal cerebral ischemia
%B Journal of Cerebral Blood Flow and Metabolism
%D 2010
%@ 
%C United States
%I 
%V 30
%I Nature Publishing Group
%P 230-241
%E 


%0 Journal Article
%~ IRMA
%A Banister, Samuel
%A Roeda, Dirk
%A Dolle, Frederic
%A Kassiou, Michael
%T Fluorine-18 chemistry for PET: A concise introduction
%B Current Radiopharmaceuticals
%D 2010
%@ 
%C The Netherlands
%I 
%V 3
%I Bentham Science Publishers Ltd.
%P 68-80
%E 


%0 Journal Article
%~ IRMA
%A Beinat, Corinne
%A Banister, Samuel
%A Moussa, Iman
%A Reynolds, Aaron
%A McErlean, Christopher
%A Kassiou, Michael
%T Insights into structure-activity relationships and CNS therapeutic applications of NR2B selective antagonists
%B Current Medicinal Chemistry
%D 2010
%@ 
%C Netherlands
%I 
%V 17
%I Bentham Science Publishers Ltd.
%P 4166-4190
%E 


%0 Conference Proceedings
%~ IRMA
%A Fulton, Roger
%A Meikle, Steven
%A Kyme, Andre
%A Zhou, Weidong (Victor)
%A Popovic, Kata
%A Kassiou, Michael
%A Akhtar, Mahmood
%T Motion-corrected microPET brain imaging of conscious rats
%B 2009 World Molecular Imaging Conference
%D 2010
%@ 
%C USB drive/online
%I 
%V 
%I Online
%P 
%E 


%0 Journal Article
%~ IRMA
%A Banister, Samuel
%A Moussa, Iman
%A Jordan, Meredith
%A Coster, Mark J
%A Kassiou, Michael
%T Oxo-bridged isomers of aza-trishomocubane sigma (o) receptor ligands: Synthesis, in vitro binding, and molecular modeling
%B Bioorganic and Medicinal Chemistry Letters: the tetrahedron journal for research at the interface of chemistry and biology
%D 2010
%@ 
%C United Kingdom
%I 
%V 20
%I Pergamon
%P 145-148
%E 


%0 Journal Article
%~ IRMA
%A Gunosewoyo, Hendra
%A Kassiou, Michael
%T P2X purinergic receptor ligands: Recently patented compounds
%B Expert Opinion on Therapeutic Patents
%D 2010
%@ 
%C London, United Kingdom
%I 
%V 20
%I Informa Healthcare
%P 625-646
%E 


%0 Journal Article
%~ IRMA
%A Giboureau, Nicolas
%A Mat Som, Ian
%A Boucher, Aurelie
%A Guilloteau, Denis D.
%A Kassiou, Michael
%T PET Radioligands for the Vesicular Acetylcholine Transporter (VAChT)
%B Current Topics in Medicinal Chemistry
%D 2010
%@ 
%C Netherlands
%I 
%V 10
%I Bentham Science Publishers Ltd.
%P 1569-1583
%E 


%0 Journal Article
%~ IRMA
%A Reynolds, Aaron
%A Hanani, Raphy
%A Hibbs, David
%A Damont, Annelaure
%A Da Pozzo, Eleonora
%A Selleri, Silvia
%A Dolle, Frederic
%A Martini, Claudia
%A Kassiou, Michael
%T Pyrazolo[1,5-a]pyrimidine acetamides: 4-Phenyl alkyl ether derivatives as potent ligands for the 18 kDa translocator protein (TSPO)
%B Bioorganic and Medicinal Chemistry Letters: the tetrahedron journal for research at the interface of chemistry and biology
%D 2010
%@ 
%C United Kingdom
%I 
%V 20
%I Pergamon
%P 5799-5802
%E 


%0 Journal Article
%~ IRMA
%A Luus, Christopher
%A Hanani, Raphy
%A Reynolds, Aaron
%A Kassiou, Michael
%T The development of PET radioligands for imaging the translocator protein (18 kDa): What have we learned?
%B Journal of Labelled Compounds and Radiopharmaceuticals
%D 2010
%@ 
%C United Kingdom
%I 
%V 53
%I John Wiley & Sons
%P 501-510
%E 


%0 Journal Article
%~ IRMA
%A Valette, Heric
%A Xiao, Yingxian
%A Schollhorn-Peyronneau, Marie-Anne
%A Damont, Annelaure
%A Kosikowski, Alan
%A Wei, Zhi-Liang
%A Kassiou, Michael
%A Kellar, Kenneth J
%A Dolle, Frederic
%A Bottlaender, Michael
%T 18F-ZW-104: A New Radioligand for Imaging Neuronal Nicotinic Acetylcholine Receptors-In Vitro Binding Properties and PET Studies in Baboons
%B The Journal of Nuclear Medicine
%D 2009
%@ 
%C United States
%I 
%V 50
%I Society of Nuclear Medicine
%P 1349-1355
%E 


%0 Journal Article
%~ IRMA
%A Doorduin, J
%A Klein, HC
%A Dierckx, RA
%A James, Michelle
%A Kassiou, Michael
%A De Vries, Erik
%T [11C]-DPA-713 and [18F]-DPA-714 as new PET tracers for TSPO: A comparison with [11C]-(R)-PK11195 in a rat model of herpes encephalitis
%B Molecular Imaging and Biology
%D 2009
%@ 
%C United States
%I 
%V 11
%I Springer
%P 386-398
%E 


%0 Journal Article
%~ IRMA
%A Damont, Annelaure
%A van Camp, N
%A Kuhnast, B
%A Hinnen, Francoise
%A Boisgard, R
%A Chauveau, Fabien
%A Boutin, Herve
%A Probst, K
%A Clark, J
%A Katsifis, Andrew
%A Kassiou, Michael
%T [18F]DPA-714, [18F]PBR111 and [18F]FEDAA1106 as potent PBR pet-imaging candidates:  Radiosynthesis and comparative studies
%B Journal of Labelled Compounds and Radiopharmaceuticals
%D 2009
%@ 
%C United Kingdom
%I 
%V 52
%I John Wiley & Sons
%P S122-S122
%E 


%0 Conference Proceedings
%~ IRMA
%A Banister, Samuel
%A Coster, Mark J
%A Kassiou, Michael
%T A versatile polycyclic scaffold for the discovery of selective sigma (sigma) receptor ligands (POSTER/TALK)
%B 7th AFMC International Medicinal Chemistry Symposium
%D 2009
%@ 
%C N/A
%I 
%V 0
%I N/A
%P 0-0
%E 


%0 Journal Article
%~ IRMA
%A Truong, Linda
%A Allbutt, Haydn
%A Coster, Mark
%A Kassiou, Michael
%A Henderson, Jasmine
%T Behavioural effects of a selective NMDA NR1A/2B receptor antagonist in rats with unilateral 6-OHDA+ parafascicular lesions
%B Brain Research Bulletin
%D 2009
%@ 
%C United States
%I 
%V 78
%I Elsevier
%P 91-96
%E 


%0 Journal Article
%~ IRMA
%A Kassiou, Michael
%A Banati, Richard
%A Holsinger, Ramsworth (Damian)
%A Meikle, Steven
%T Challenges in molecular imaging of Parkinson's disease: A brief overview
%B Brain Research Bulletin
%D 2009
%@ 
%C United States
%I 
%V 78
%I Elsevier
%P 105-108
%E 


%0 Journal Article
%~ IRMA
%A Chauveau, Fabien
%A Van Camp, Nadja
%A Dolle, Frederic
%A Kuhnast, B
%A Hinnen, Francoise
%A Damont, Annelaure
%A Boutin, Herve
%A James, Michelle
%A Kassiou, Michael
%A Tavitian, Bertrand
%T Comparative evaluation of the translocator protein radioligands (11)C-DPA-713, (18)F-DPA-714, and (11)C-PK11195 in a rat model of acute neuroinflammation
%B The Journal of Nuclear Medicine
%D 2009
%@ 
%C United States
%I 
%V 50
%I Society of Nuclear Medicine
%P 468-476
%E 


%0 Conference Proceedings
%~ IRMA
%A Kassiou, Michael
%T Discovery of new therapeutic immunomodulator drugs as a pathway for treating brain disease (POSTER/TALK)
%B Plant Nutraceuticals and Bioactive Molecules:  A Growth Opportunity for the Pharmaceutical Industry in Australia and India
%D 2009
%@ 
%C N/A
%I 
%V 0
%I N/A
%P 0-0
%E 


%0 Journal Article
%~ IRMA
%A Warraich, Sadaf
%A Allbutt, Haydn
%A Billing, Robyn
%A Radford, Jane
%A Coster, Mark
%A Kassiou, Michael
%A Henderson, Jasmine
%T Evaluation of behavioural effects of a selective NMDA NR1A/2B receptor antagonist in the unilateral 6-OHDA lesion rat model
%B Brain Research Bulletin
%D 2009
%@ 
%C United States
%I 
%V 78
%I Elsevier
%P 85-90
%E 


%0 Journal Article
%~ IRMA
%A Edington, Amelia
%A McKinzie, Audra
%A Reynolds, Aaron
%A Kassiou, Michael
%A Ryan, Renae
%A Vandenberg, Robert
%T Extracellular loops 2 and 4 of GLYT2 are required for N-arachidonylglycine inhibition of glycine transport
%B Journal of Biological Chemistry
%D 2009
%@ 
%C United States
%I 
%V 284
%I American Society for Biochemistry and Molecular Biology, Inc.
%P 36424-36430
%E 


%0 Conference Proceedings
%~ IRMA
%A Kassiou, Michael
%T Imaging immune response in the CNS - Applications for therapeutic development (POSTER/TALK)
%B 7th AFMC International Medicinal Chemistry Symposium
%D 2009
%@ 
%C N/A
%I 
%V 
%I N/A
%P 
%E 


%0 Journal Article
%~ IRMA
%A Endres, Christopher
%A Pomper, M.
%A James, Michelle
%A Uzuner, Ovsev
%A Hammoud, Dima
%A Watkins, Crystal
%A Reynolds, Aaron
%A Hilton, John
%A Dannals, Robert F.
%A Kassiou, Michael
%T Initial evaluation of 11C-DPA-713, a novel TSPO PET ligand, in humans
%B The Journal of Nuclear Medicine
%D 2009
%@ 
%C United States
%I 
%V 50
%I Society of Nuclear Medicine
%P 1276-1282
%E 


%0 Journal Article
%~ IRMA
%A Leaver, Katherine
%A Allbutt, Haydn
%A Creber, Nathan
%A Kassiou, Michael
%A Henderson, Jasmine
%T Oral pre-treatment with epigallocatechin gallate in 6-OHDA lesioned rats produces subtle symptomatic relief but not neuroprotection
%B Brain Research Bulletin
%D 2009
%@ 
%C United States
%I 
%V 80
%I Elsevier
%P 397-402
%E 


%0 Patents Applied Measures
%~ IRMA
%A Kassiou, Michael
%A James, Michelle
%A Luus, Christopher
%T Preparation of imidazo[1,2-b]pyridazin-3-ylethanamide and 2-substituted phenylacetamide derivatives as translocator protein ligands
%B 
%D 2009
%@ WO2009079683 (A1)
%C 
%I 
%V 
%I 
%P 
%E 


%0 Journal Article
%~ IRMA
%A Gunosewoyo, Hendra
%A Coster, Mark J
%A Bennett, Maxwell
%A Kassiou, Michael
%T Purinergic P2X(7) receptor antagonists:Chemistry and fundamentals of biological screening
%B Bioorganic and Medicinal Chemistry: the tetrahedron journal for research at the interface of chemistry and biology
%D 2009
%@ 
%C United Kingdom
%I 
%V 17
%I Pergamon Elsevier
%P 4861-4865
%E 


%0 Journal Article
%~ IRMA
%A Dolle, Frederic
%A Luus, Christopher
%A Reynolds, Aaron
%A Kassiou, Michael
%T Radiolabelled molecules for imaging the translocator protein (18 kDa) using positron emission tomography
%B Current Medicinal Chemistry
%D 2009
%@ 
%C Netherlands
%I 
%V 16
%I Bentham Science Publishers Ltd.
%P 2899-2923
%E 


%0 Journal Article
%~ IRMA
%A Reynolds, Aaron
%A Kassiou, Michael
%T Recent advances in the Mitsunobu reaction: Modifications and applications to biologically active molecules
%B Current Organic Chemistry
%D 2009
%@ 
%C Hilversum, Netherlands
%I 
%V 13
%I Bentham Science Publishers Ltd.
%P 1610-1632
%E 


%0 Conference Proceedings
%~ IRMA
%A Moussa, Iman
%A Coster, Mark J
%A Kassiou, Michael
%T Synthesis and pharmacological evaluation of novel sigma receptor ligands (POSTER/TALK)
%B 7th AFMC International Medicinal Chemistry Symposium
%D 2009
%@ 
%C N/A
%I 
%V 0
%I N/A
%P 0-0
%E 


%0 Journal Article
%~ IRMA
%A Scarf, Alana
%A Ittner, Lars
%A Kassiou, Michael
%T The translocator protein (18 kDa): Central nervous system disease and drug design
%B Journal of Medicinal Chemistry
%D 2009
%@ 
%C United States
%I 
%V 52
%I American Chemical Society
%P 581-592
%E 


%0 Journal Article
%~ IRMA
%A Ioppolo, Joseph
%A Kassiou, Michael
%A Rendina, Louis
%T Water-soluble phosphonium salts containing 1,12-dicarba-closo-dodecaborane(12)
%B Tetrahedron Letters
%D 2009
%@ 
%C UK
%I 
%V 50
%I Pergamon Elsevier
%P 6457-6461
%E 


%0 Journal Article
%~ IRMA
%A Dolle, Frederic
%A Damont, Annelaure
%A Valette, Heric
%A Hinnen, Francoise
%A Kuhnast, B
%A Saba, W
%A Schollhorn-Peyronneau, Marie-Anne
%A Kozikowski, Alan P
%A Bottlaender, Michel
%A Kassiou, Michael
%T ZW-102 and ZW-104, two novel fluorine-18 labelled radioligands for imaging nicotinic acetylcholine receptors with PET
%B Journal of Labelled Compounds and Radiopharmaceuticals
%D 2009
%@ 
%C United Kingdom
%I 
%V 52
%I John Wiley & Sons
%P S364-S364
%E 


%0 Journal Article
%~ IRMA
%A van Dijk, Addy
%A Johnston, Christopher
%A Allbutt, Haydn
%A Kassiou, Michael
%A Henderson, Jasmine
%T Behavioural effects of trishomocubanes in rats with unilateral 6-hydroxydopamine lesions
%B Behavioural Brain Research
%D 2008
%@ 
%C Netherlands
%I 
%V 190
%I Elsevier
%P 14-21
%E 


%0 Journal Article
%~ IRMA
%A Gunosewoyo, Hendra
%A Liu, Guo
%A Bennett, Maxwell
%A Coster, Mark J
%A Kassiou, Michael
%T Cubyl amides: Novel P2X(7) receptor antagonists
%B Bioorganic and Medicinal Chemistry Letters: the tetrahedron journal for research at the interface of chemistry and biology
%D 2008
%@ 
%C United Kingdom
%I 
%V 18
%I Pergamon
%P 3720-3723
%E 


%0 Journal Article
%~ IRMA
%A Besret, Laurent
%A Dolle, Frederic
%A Herard, Anne-Sophie
%A Guillermier, Martine
%A Demphel, Stephane
%A Hinnen, Francoise
%A Coulon, Christine
%A Ottaviani, Michelle
%A Bottlaender, Michel
%A Hantraye, Philippe
%A Kassiou, Michael
%T Dopamine D1 Receptor Imaging in the Rodent and Primate Brain Using the Isoquinoline (+)-[(11)C]A-69024 and Positron Emission Tomography
%B Journal of Pharmaceutical Sciences
%D 2008
%@ 
%C United States
%I 
%V 97
%I John Wiley & Sons
%P 2811-2819
%E 


%0 Journal Article
%~ IRMA
%A James, Michelle
%A Fulton, Roger R.
%A Vercoullie, Johnny
%A Henderson, David J.
%A Garreau, Lucette
%A Chalon, Sylvie
%A Dolle, Frederic
%A Selleri, Silvia
%A Guilloteau, Denis
%A Kassiou, Michael
%T DPA-714, a New Translocator Protein-Specific Ligand: Synthesis, Radiofluorination, and Pharmacologic Characterization
%B The Journal of Nuclear Medicine
%D 2008
%@ 
%C United States
%I 
%V 49
%I Society of Nuclear Medicine
%P 814-822
%E 


%0 Journal Article
%~ IRMA
%A Leaver, Katherine
%A Allbutt, Haydn
%A Creber, N
%A Kassiou, Michael
%A Henderson, Jasmine
%T Neuroprotective effects of a selective N-methyl-D-aspartate NR2B receptor antagonist in the 6-hydroxydopamine rat model of Parkinson's disease
%B Clinical and Experimental Pharmacology and Physiology
%D 2008
%@ 
%C Australia
%I 
%V 35
%I Wiley-Blackwell Publishing
%P 1388-1394
%E 


%0 Journal Article
%~ IRMA
%A Henderson, Jasmine
%A Lanciego, Jose
%A Smith, Yoland
%A Gundlach, Andrew
%A Kassiou, Michael
%T Proceedings of the 2007 International Brain Research Organisation Satellite Meeting "Movement Disorders: Focus on the Thalamus and Basal Ganglia" held in Sydney, Australia, 10-11 July, 2007
%B Brain Research Bulletin
%D 2008
%@ 
%C United States
%I 
%V 78
%I Elsevier
%P 53-54
%E 


%0 Conference Proceedings
%~ IRMA
%A Fulton, Roger
%A Kyme, Andre
%A Zhou, Victor
%A Leaver, Katherine
%A Kassiou, Michael
%A Lehnert, Wencke
%A Meikle, Steven
%T Progress towards microPET imaging of small, awake laboratory animals
%B 2008 World Molecular Imaging Congress
%D 2008
%@ 
%C Europe
%I 
%V 
%I World Molecular Imaging Congress
%P 
%E 


%0 Book Chapter
%~ IRMA
%A Guenther, Katharina
%A Hambley, Trevor
%A Kassiou, Michael
%T Radiolabelled probes for imaging multidrug resistance using single photon emission tomography (SPECT) and positron emission tomography (PET)
%B Multidrug Resistance:  Biological and Pharmaceutical Advances in Antitumour Treatment
%D 2008
%@ 
%C India
%I 
%V 1
%I Research Signpost
%P 291-320
%E Nicola Antonio Colabufo


%0 Journal Article
%~ IRMA
%A Damont, Annelaure
%A Hinnen, Francoise
%A Kuhnast, B
%A Schollhorn-Peyronneau, Marie-Anne
%A James, Michelle
%A Luus, Christopher
%A Tavitian, Bertrand
%A Kassiou, Michael
%A Dolle, Frederic
%T Radiosynthesis of [(18)F]DPA-714, a selective radioligand for imaging the translocator protein (18 kDa) PET
%B Journal of Labelled Compounds and Radiopharmaceuticals
%D 2008
%@ 
%C United Kingdom
%I 
%V 51
%I John Wiley & Sons
%P 286-292
%E 


%0 Journal Article
%~ IRMA
%A Dolle, Frederic
%A Langle, Sandrine
%A Roger, Gaelle
%A Fulton, Roger R.
%A Lagnel, Beatrice
%A Henderson, David J.
%A Hinnen, Francoise
%A Paine, Taliesha
%A Coster, Mark J
%A Valette, Heric
%A Kassiou, Michael
%A et al, 
%T Synthesis and In-Vivo Evaluation of [(11)C]p-PVP-MEMA as a PET Radioligand for Imaging Nicotinic Receptors
%B Australian Journal of Chemistry: an international journal for chemical science
%D 2008
%@ 
%C Australia
%I 
%V 61
%I CSIRO Publishing
%P 438-445
%E 


%0 Conference Proceedings
%~ IRMA
%A Doorduin, J
%A Klein, HC
%A James, Michelle
%A Kassiou, Michael
%A Dierckx, RA
%A Vries, EFJ
%T (18F)DPA-714 as a novel PET tracer for PBR: A comparison with (11C)PK11195 in a rat model of HSV encephalitis
%B 17th International Symposium on Radiopharmaceutical Sciences
%D 2007
%@ 
%C  
%I 
%V 
%I John Wiley & Sons
%P 
%E 


%0 Journal Article
%~ IRMA
%A Banister, Samuel
%A Clegg, Jack
%A Coster, Mark
%A Jolliffe, Katrina
%A Kassiou, Michael
%T (1R,2S,3R,6S,7R,8S)-Tricyclo[6.2.1.02,7]-undeca-4,9-diene-3,6-diol
%B Acta Crystallographica. Section E: Structure Reports Online
%D 2007
%@ 
%C Denmark
%I 
%V E63
%I Wiley-Blackwell Publishing
%P o92-o93
%E 


%0 Journal Article
%~ IRMA
%A Emond, Patrick
%A Mavel, Sylvie
%A Zea-Ponce, Y
%A Kassiou, Michael
%A Garreau, Lucette
%A Bodard, Sylvie
%A Drossard, Marie-Laure
%A Chalon, Sylvie
%A Guilloteau, Denis
%T (E)-[125I]-5-AOIBV: a SPECT radioligand for the vesicular acetylcholine transporter
%B Nuclear Medicine and Biology
%D 2007
%@ 
%C United States
%I 
%V 34
%I Elsevier
%P 967-971
%E 


%0 Journal Article
%~ IRMA
%A Boutin, Herve
%A Chauveau, Fabien
%A Thominiaux, Cyrille
%A Gregoire, Marie-Claude
%A James, Michelle L
%A Trebossen, Regine
%A Hantraye, Philippe
%A Dolle, Frederic
%A Tavitian, Bertrand
%A Kassiou, Michael
%T 11C-DPA-713:  A novel peripheral benzodiazepine receptor PET ligand for in vivo imaging of neuroinflammation
%B The Journal of Nuclear Medicine
%D 2007
%@ 
%C United States
%I 
%V 48
%I Society of Nuclear Medicine
%P 573-581
%E 


%0 Journal Article
%~ IRMA
%A Kozikowski, Alan P
%A Chellappan, Sheela K
%A Henderson, David
%A Fulton, Roger
%A Giboureau, Nicolas
%A Xiao, Yingxian
%A Wei, Zhi-Liang
%A Guilloteau, Denis
%A Emond, Patrick
%A Dolle, Frederic
%A Kassiou, Michael
%A et al, 
%T Acetylenic pyridines for use in PET imaging of nicotinic receptors
%B ChemMedChem: chemistry enabling drug discovery
%D 2007
%@ 
%C Germany
%I 
%V 2
%I Wiley - V C H Verlag GmbH & Co. KGaA
%P 54-57
%E 


%0 Journal Article
%~ IRMA
%A Quinlivan, Mitchell
%A Chalon, Sylvie
%A Vergote, Jackie
%A Henderson, Jasmine
%A Katsifis, AG
%A Kassiou, Michael
%A Guilloteau, Denis
%T Decreased vesicular acetylcholine transporter and alpha-4beta-2 nicotinic receptor density in the rat brain following 192 IgG-saporin immunolesioning
%B Neuroscience Letters
%D 2007
%@ 
%C Ireland
%I 
%V 415
%I Elsevier
%P 97-101
%E 


%0 Conference Proceedings
%~ IRMA
%A James, Michelle
%A Fulton, Roger R.
%A Vercouille, J
%A Henderson, David J.
%A Garreau, Lucette
%A Eberl, Stefan
%A Chalon, Sylvie
%A Selleri, Silvia
%A Dolle, Frederic
%A Guilloteau, Denis
%A Kassiou, Michael
%T DPA-714 A new translocator protein (18kDa) ligand: Synthesis, radiofluorination and pharmacological characterisation
%B 17th International Symposium on Radiopharmaceutical Sciences
%D 2007
%@ 
%C  
%I 
%V 50
%I John Wiley & Sons
%P 
%E 


%0 Conference Proceedings
%~ IRMA
%A Mavel, Sylvie
%A Zea-Ponce, Y
%A Garreau, Lucette
%A Chalon, Sylvie
%A Kassiou, Michael
%A Guilloteau, Denis
%A Emond, Patrick
%T E-((R,R) and (S,S))-5-(125I)-AOIBV: Potential SPECT tracers in vivo studies of the vesicular AcetylCholine Transporter (VACht)
%B 17th International Symposium on Radiopharmaceutical Sciences
%D 2007
%@ 
%C  
%I 
%V 
%I John Wiley & Sons
%P 
%E 


%0 Journal Article
%~ IRMA
%A Giboureau, Nicolas
%A Emond, Patrick
%A Fulton, Roger R.
%A Henderson, David J.
%A Chalon, Sylvie
%A Garreau, Lucette
%A Roselt, Peter
%A Eberl, Stefan
%A Mavel, Sylvie
%A Bodard, Sylvie
%A Fulham, Michael
%A Kassiou, Michael
%A et al, 
%T Ex vivo and in vivo evaluation of (2R,3R)-5-[18F]-fluoroethoxy- and fluoropropoxy-benzovesamicol, as PET radioligands for the vesicular acetylcholine transporter
%B Synapse (New York)
%D 2007
%@ 
%C United States
%I 
%V 61
%I John Wiley & Sons
%P 962-670
%E 


%0 Journal Article
%~ IRMA
%A Naidoo (Naidoo-Variawa), Sheruna
%A Hey Cunningham, Alison
%A Lehnert, Wencke
%A Kench, Peter
%A Kassiou, Michael
%A Banati, Richard
%A Meikle, Steven
%T High-resolution imaging of the large non-human primate brain using microPET: a feasibility study
%B Physics in Medicine and Biology
%D 2007
%@ 
%C United Kingdom
%I 
%V 52
%I Institute of Physics Publishing
%P 6627-6638
%E 


%0 Journal Article
%~ IRMA
%A Collier, Thomas Lee
%A Waterhouse, Rikki N
%A Kassiou, Michael
%T Imaging sigma receptors:  Applications in drug development
%B Current Pharmaceutical Design
%D 2007
%@ 
%C Netherlands
%I 
%V 13
%I Bentham Science Publishers Ltd.
%P 51-72
%E 


%0 Journal Article
%~ IRMA
%A Kassiou, Michael
%T Molecular imaging in drug development (Editorial)
%B Current Pharmaceutical Design
%D 2007
%@ 
%C Netherlands
%I 
%V 13
%I Bentham Science Publishers Ltd.
%P 1-1
%E 


%0 Journal Article
%~ IRMA
%A Gunosewoyo, Hendra
%A Coster, Mark
%A Kassiou, Michael
%T Molecular probes for P2X7 receptor studies
%B Current Medicinal Chemistry
%D 2007
%@ 
%C Netherlands
%I 
%V 14
%I Bentham Science Publishers Ltd.
%P 1505-1523
%E 


%0 Journal Article
%~ IRMA
%A Cagnin, Annachiara
%A Kassiou, Michael
%A Meikle, Steven
%A Banati, Richard
%T Positron emission tomography imaging of neuroinflammation
%B Neurotherapeutics
%D 2007
%@ 
%C United States
%I 
%V 4
%I American Society for Experimental Neurotherapeutics
%P 443-452
%E 


%0 Conference Proceedings
%~ IRMA
%A Kassiou, Michael
%A Chellappan, Sheela K
%A Henderson, David
%A Fulton, Roger
%A Giboureau, Nicolas
%A Xiao, Yingxian
%A Wei, Zhi-Liang
%A Guilloteau, Denis
%A Emond, Patrick
%A Dolle, Frederic
%A et al, 
%T Radiosynthesis and preliminary evaluation of ZW-90 and ZW-110, two novel acetylenic pyridines for imaging nicotonic receptors
%B 17th International Symposium on Radiopharmaceutical Sciences
%D 2007
%@ 
%C  
%I 
%V 
%I John Wiley & Sons
%P 
%E 


%0 Conference Proceedings
%~ IRMA
%A Giboureau, Nicolas
%A Chalon, Sylvie
%A Garreau, Lucette
%A Kassiou, Michael
%A Emond, Patrick
%A Guilloteau, Denis
%T Rat distribution of (18F)-Fuoropropoxy- and (18F)-Fluoroethoxybenzovesamicol, as PET radioligands for the vesicular acetylcholine transporter (VACht)
%B 17th International Symposium on Radiopharmaceutical Sciences
%D 2007
%@ 
%C  
%I 
%V 
%I John Wiley & Sons
%P 
%E 


%0 Conference Proceedings
%~ IRMA
%A Creelman, Anna
%A Thominiaux, Cyrille
%A Chauveau, Fabien
%A Fulton, Roger R.
%A Kuhnast, B
%A Henderson, David J.
%A Boutin, Herve
%A Selleri, Silvia
%A McGregor, Iain
%A Hantraye, Philippe
%A Kassiou, Michael
%A et al, 
%T Synthesis and evaluation of the translocator protein (18kDa) (TSPO) ligand (11C)DPA0715 in rat and non-human primate
%B 17th International Symposium on Radiopharmaceutical Sciences
%D 2007
%@ 
%C  
%I 
%V 
%I John Wiley & Sons
%P 
%E 


%0 Conference Proceedings
%~ IRMA
%A Langley, S
%A Roger, Gaelle
%A Fulton, Roger R.
%A Lagnel, Beatrice
%A Henderson, David J.
%A Hinnen, F
%A Bottlaender, Michel
%A Dolle, Frederic
%A Kassiou, Michael
%T Synthesis and in vivo evaluation of (11c)P-PVP-MEMA as a PET radioligand for Imaging nicotonic receptors
%B 17th International Symposium on Radiopharmaceutical Sciences
%D 2007
%@ 
%C  
%I 
%V 
%I John Wiley & Sons
%P 
%E 


%0 Journal Article
%~ IRMA
%A Liu, Xiang
%A Banister, Samuel
%A Christie, MacDonald
%A Banati, Richard
%A Meikle, Steven
%A Coster, Mark
%A Kassiou, Michael
%T Trishomocubanes:  Novel sigma ligands modulate cocaine-induced behavioural effects
%B European Journal of Pharmacology
%D 2007
%@ 
%C Amsterdam
%I 
%V 555
%I Elsevier Science
%P 37-42
%E 


%0 Journal Article
%~ IRMA
%A Truong, Linda
%A Allbutt, Haydn
%A Kassiou, Michael
%A Henderson, Jasmine
%T Developing a preclinical model of Parkinson's disease: a study of behaviour in rats with graded 6-OHDA lesions
%B Behavioural Brain Research
%D 2006
%@ 
%C Netherlands
%I 
%V 169
%I Elsevier
%P 1-9
%E 


%0 Journal Article
%~ IRMA
%A James, Michelle
%A Selleri, Silvia
%A Kassiou, Michael
%T Development of ligands for the peripheral benzodiazepine receptor
%B Current Medicinal Chemistry
%D 2006
%@ 
%C Netherlands
%I 
%V 13
%I Bentham Science Publishers Ltd.
%P 1991-2001
%E 


%0 Journal Article
%~ IRMA
%A Thominiaux, Cyrille
%A Dolle, Frederic
%A James, Michelle
%A Bramoulle, Yann
%A Boutin, Herve
%A Besret, Laurent
%A Gregoire, M. C.
%A Valette, Heric
%A Bottlaender, Michel
%A Tavitian, Bertrand
%A Kassiou, Michael
%A et al, 
%T Improved synthesis of the peripheral benzodiazepine receptor ligand C-11 DPA-713 using C-11 methyl triflate
%B Applied Radiation and Isotopes
%D 2006
%@ 
%C United Kingdom
%I 
%V 64
%I Pergamon
%P 570-573
%E 


%0 Journal Article
%~ IRMA
%A Cagnin, Annachiara
%A Kassiou, Michael
%A Meikle, Steven
%A Banati, Richard
%T In vivo evidence for microglial activation in neurodegenerative dementia
%B Acta Neurologica Scandinavica
%D 2006
%@ 
%C Denmark
%I 
%V 114
%I Wiley-Blackwell Publishing
%P 107-114
%E 


%0 Journal Article
%~ IRMA
%A Thominiaux, Cyrille
%A de Bruin, Beatrice
%A Bramoulle, Yann
%A Hinnen, Francoise
%A Demphel, Stephane
%A Valette, Heric
%A Bottlaender, Michel
%A Besret, Laurent
%A Kassiou, Michael
%A Dolle, Frederic
%T Radiosynthesis of (E)-N-(2- C-11 methoxybenzyl)-3-phenyl-acrylamidine, a novel subnanomolar NR2B subtype-selective NMDA receptor antagonist
%B Applied Radiation and Isotopes
%D 2006
%@ 
%C United Kingdom
%I 
%V 64
%I Pergamon
%P 348-354
%E 


%0 Journal Article
%~ IRMA
%A Assaad, Thaer
%A Mavel, Sylvie
%A Parsons, Stanley M.
%A Kruse, Shane E.
%A Galineau, Laurent
%A Allouchi, Hassan
%A Kassiou, Michael
%A Chalon, Sylvie
%A Guilloteau, Denis
%A Emond, Patrick
%T Synthesis and in vitro evaluation of N-substituted aza-trozamicol analogs as vesicular acetylcholine transporter ligands
%B Bioorganic and Medicinal Chemistry Letters: the tetrahedron journal for research at the interface of chemistry and biology
%D 2006
%@ 
%C United Kingdom
%I 
%V 16
%I Pergamon
%P 2654-2657
%E 


%0 Journal Article
%~ IRMA
%A Vercouillie, Johnny
%A Mavel, Sylvie
%A Galineau, Laurent
%A Ragusa, Tiziana
%A Innis, Robert
%A Chalon, Sylvie
%A Kassiou, Michael
%A Dolle, Frederic
%A Besnard, Jean-Claude
%A Guilloteau, D
%A et al, 
%T Synthesis and in vitro evaluation of novel derivatives of diphenylsulfide as serotonin transporter ligands
%B Bioorganic and Medicinal Chemistry Letters: the tetrahedron journal for research at the interface of chemistry and biology
%D 2006
%@ 
%C United Kingdom
%I 
%V 16
%I Pergamon
%P 1297-1300
%E 


%0 Journal Article
%~ IRMA
%A Issa, Fatiah
%A Kassiou, Michael
%A Chan, Hak-Kim (Kim)
%A McLeod, Malcolm
%T Synthesis and radiolabelling of ipratropium and tiotropium for use as PET ligands in the study of inhaled drug deposition
%B Australian Journal of Chemistry: an international journal for chemical science
%D 2006
%@ 
%C Australia
%I 
%V 59
%I CSIRO Publishing
%P 53-58
%E 


%0 Journal Article
%~ IRMA
%A Liu, Xiang
%A Banister, Samuel
%A Christie, MacDonald
%A Banati, Richard
%A Meikle, Steven
%A Coster, Mark
%A Kassiou, Michael
%T Trishomocubanes: Novel Sigma ligands modulate cocaine-induced behavioural effects
%B European Journal of Pharmacology
%D 2006
%@ 
%C Amsterdam
%I 
%V 555
%I Elsevier Science
%P 37-42
%E 


%0 Journal Article
%~ IRMA
%A Kassiou, Michael
%T Capabilities of PET and SPECT in pre-clinical and clinical research
%B Current Pharmaceutical Design
%D 2005
%@ 
%C Netherlands
%I 
%V 11
%I Bentham Science Publishers Ltd.
%P 3201-3201
%E 


%0 Journal Article
%~ IRMA
%A Liu, Xiang
%A Mattner, Filomena
%A Katsifis, Andrew
%A Christie, MacDonald
%A Kassiou, Michael
%T Influence of Trishomocubanes on Sigma Receptor Binding of N-(1-Benzylpiperidin- 4-yl)-4-[123I]iodobenzamide In Vivo in the Rat Brain
%B Medicinal Chemistry
%D 2005
%@ 
%C Netherlands
%I 
%V 1
%I Bentham Science Publishers Ltd.
%P 31-38
%E 


%0 Journal Article
%~ IRMA
%A Kassiou, Michael
%A Meikle, Steven
%A Banati, Richard
%T Ligands for peripheral benzodiazepine binding sites in glial cells
%B Brain Research Reviews
%D 2005
%@ 
%C Netherlands
%I 
%V 48
%I Elsevier
%P 207-210
%E 


%0 Conference Proceedings
%~ IRMA
%A Kassiou, Michael
%A Bruin, B.
%A Demphel, S.
%A Besret, L.
%A Hinnen, F
%A Dolle, Frederic
%A Bramoulle, Y.
%A Thominiaux, C.
%A Bottlaender, M.
%T Radiosynthesis of (E)-N-(2-[11C]methoxybenzyl)-3-phenyl-acrylamidine, a novel subnanomolar NR2B subtype-selective NMDA receptor ligand
%B 16th International Symposium on Radiopharmaceutical Chemistry
%D 2005
%@ 
%C United Kingdom
%I 
%V 48
%I Wiley
%P s179-s179
%E 


%0 Journal Article
%~ IRMA
%A Mohamed, Armin
%A Eberl, Stefan
%A Fulham, Michael
%A Kassiou, Michael
%A Zaman, Aysha
%A Henderson, David J.
%A Beveridge, Scott
%A Constable, Christopher J.
%A Lo, Sing Kai
%T Sequential 123I-iododexetimide scans in temporal lobe epilepsy: comparison with neuroimaging scans (MR imaging and F-18-FDG PET imaging)
%B European Journal of Nuclear Medicine and Molecular Imaging
%D 2005
%@ 
%C Germany
%I 
%V 32
%I Springer
%P 180-185
%E 


%0 Journal Article
%~ IRMA
%A Meikle, Steven
%A Kench, Peter
%A Kassiou, Michael
%A Banati, Richard
%T Small animal SPECT and its place in the matrix of molecular imaging technologies
%B Physics in Medicine and Biology
%D 2005
%@ 
%C United Kingdom
%I 
%V 50
%I Institute of Physics Publishing
%P R45-R61
%E 


%0 Journal Article
%~ IRMA
%A Zea-Ponce, Yolanda
%A Mavel, Sylvie
%A Assaad, Thaer
%A Kruse, Shane E.
%A Parsons, Stanley M.
%A Emond, Patrick
%A Chalon, Sylvie
%A Giboureau, Nicolas
%A Kassiou, Michael
%A Guilloteau, D
%T Synthesis and in vitro evaluation of new benzovesamicol analogues as potential imaging probes for the vesicular acetylcholine transporter
%B Bioorganic and Medicinal Chemistry: the tetrahedron journal for research at the interface of chemistry and biology
%D 2005
%@ 
%C United Kingdom
%I 
%V 13
%I Pergamon Elsevier
%P 745-753
%E 


%0 Journal Article
%~ IRMA
%A Kassiou, Michael
%A Dannals, Robert F.
%A Liu, Xiang
%A Wong, Dean F.
%A Ravert, Hayden T.
%A Scheffel, Ursula A.
%T Synthesis and in vivo evaluation of a new PET radioligand for studying sigma-2 receptors
%B Bioorganic and Medicinal Chemistry: the tetrahedron journal for research at the interface of chemistry and biology
%D 2005
%@ 
%C United Kingdom
%I 
%V 13
%I Pergamon Elsevier
%P 3623-3626
%E 


%0 Conference Proceedings
%~ IRMA
%A Fulham, Michael
%A Kassiou, Michael
%A Dolle, Frederic
%A Thomson, Sally
%A Henderson, David
%A James, Michelle
%A Eberl, Stefan
%A Fulton, Roger R.
%A Allan, Robin
%T Synthesis and In Vivo Evaluation of a Novel Peripheral Benzodiazepine Receptor PET Radioligand
%B 16th International Symposium on Radiopharmaceutical Chemistry
%D 2005
%@ 
%C United Kingdom
%I 
%V 
%I Wiley
%P s3-s3
%E 


%0 Journal Article
%~ IRMA
%A James, Michelle
%A Fulton, Roger
%A Henderson, David
%A Eberl, Stefan
%A Meikle, Steven
%A Thomson, Sally
%A Allan, Robin
%A Dolle, Frederic
%A Fulham, Michael
%A Kassiou, Michael
%T Synthesis and in vivo evaluation of a novel peripheral benzodiazepine receptor PET radioligand
%B Bioorganic and Medicinal Chemistry: the tetrahedron journal for research at the interface of chemistry and biology
%D 2005
%@ 
%C United Kingdom
%I 
%V 13
%I Pergamon Elsevier
%P 6188-6194
%E 


%0 Journal Article
%~ IRMA
%A Henderson, David
%A Eberl, Stefan
%A Thomson, Scott
%A Smith, Adrian
%A Allan, Robin
%A Fulham, Michael
%A Loiacono, Richard
%A Kassiou, Michael
%T 3-Pyridyl Ethers As Spect Radioligands For Imaging Nicotinic Acetylcholine Receptors
%B Applied Radiation and Isotopes
%D 2004
%@ 
%C United Kingdom
%I 
%V 60
%I Pergamon
%P 669-676
%E 


%0 Journal Article
%~ IRMA
%A Katsifis, Andrew G.
%A Kassiou, Michael
%T Development Of Radioligands For In Vivo Imaging Of Gaba(A)-Benzodiazepine Receptors
%B Mini - Reviews in Medicinal Chemistry
%D 2004
%@ 
%C Netherlands
%I 
%V 4
%I Bentham Science Publishers Ltd.
%P 909-921
%E 


%0 Journal Article
%~ IRMA
%A Dolle, Frederic
%A Valette, Heric
%A Demphel, Stephane
%A Coulon, Christine
%A Ottaviani, Michelle
%A Bottlaender, Michel
%A Kassiou, Michael
%T Radiosynthesis And In Vivo Evaluation Of [11C]Ro-547312: A Novel Nr1/2B Subtype Selective Nmda Receptor Radioligand
%B Journal of Labelled Compounds and Radiopharmaceuticals
%D 2004
%@ 
%C United Kingdom
%I 
%V 47
%I John Wiley & Sons
%P 911-920
%E 


%0 Journal Article
%~ IRMA
%A Roger, Gaelle
%A Dolle, Frederic
%A de Bruin, Beatrice
%A Liu, Xiang
%A Besret, Laurent
%A Bramoulle, Yann
%A Coulon, Christine
%A Ottaviani, Michelle
%A Bottlaender, Michel
%A Valette, Heric
%A Kassiou, Michael
%T Radiosynthesis And Pharmacological Evaluation Of [11C]Emd-95885: A High Affinity Ligand For Nr2B-Containing Nmda Receptors
%B Bioorganic and Medicinal Chemistry: the tetrahedron journal for research at the interface of chemistry and biology
%D 2004
%@ 
%C United Kingdom
%I 
%V 12
%I Pergamon Elsevier
%P 3229-3237
%E 


%0 Journal Article
%~ IRMA
%A Roselt, Peter
%A Meikle, Steven
%A Kassiou, Michael
%T The Role Of Positron Emission Tomography In The Discovery And Development Of New Drugs; As Studied In Laboratory Animals
%B European Journal of Drug Metabolism and Pharmacokinetics
%D 2004
%@ 
%C Switzerland
%I 
%V 29
%I Editions Medecine et Hygiene
%P 1-6
%E 


%0 Journal Article
%~ IRMA
%A Kassiou, Michael
%A Katsifis, AG
%T PET radiochemistry in drug development and evaluation
%B Chemistry in Australia
%D 2003
%@ 
%C Melbourne, Australia
%I 
%V 70
%I Royal Australian Chemical Institute
%P 10-12
%E 


%0 Journal Article
%~ IRMA
%A Katsifis, AG
%A Mardon, Karine
%A Mattner, F
%A Loc'h, Christian
%A McPhee, M
%A Dikic, Branko
%A Kassiou, Michael
%A Ridley, Damon
%T Pharmacological evaluation of (S)-8-[123I]iodobretazenil: a radioligand for in vivo studies of central benzodiazepine receptors
%B Nuclear Medicine and Biology
%D 2003
%@ 
%C United States
%I 
%V 30
%I Elsevier
%P 191-198
%E 


%0 Conference Proceedings
%~ IRMA
%A Feng, Dagan
%A Kassiou, Michael
%A Fulham, Michael
%A Wong, Koon-Pong
%A Elberl, S
%T Quantification of 5-[123I]iodo-A-85380 in nonhuman primates using spect: parameter identifiability and stabilitty
%B Modelling and Control in Biomedical Systems 2003 (Including Biological Systems)
%D 2003
%@ 
%C UK
%I 
%V 1
%I Pergamon
%P 185-190
%E 


%0 Journal Article
%~ IRMA
%A Quinlivan, Mitchell
%A Mattner, Filomena
%A Papazian, Vahan
%A Zhou, Jia
%A Katsifis, Andrew
%A Emond, Patrick
%A Chalon, Sylvie S.
%A Kozikowski, Alan
%A Guilloteau, Denis D.
%A Kassiou, Michael
%T Synthesis and evaluation of iodine-123 labelled tricyclic tropanes as radioligands for the serotonin transporter
%B Nuclear Medicine and Biology
%D 2003
%@ 
%C United States
%I 
%V 30
%I Elsevier
%P 741-746
%E 


%0 Journal Article
%~ IRMA
%A Roger, Gaelle
%A Lagnel, Beatrice
%A Besret, Laurent
%A Bramoulle, Yann
%A Coulon, Christine
%A Ottaviani, Michelle
%A Kassiou, Michael
%A Bottlaender, Michel
%A Valette, Heric
%A Dolle, Frederic
%T Synthesis, radiosynthesis and In Vivo evaluation of 5-[3-(4-Benzylpiperidin-1-yl) prop-1-ynyl]-1, 3-dihydrobenzoimidazol-2-[11C] one, as a potent NR 1A/2B subtype selective NMDA PET radiotracer
%B Bioorganic and Medicinal Chemistry: the tetrahedron journal for research at the interface of chemistry and biology
%D 2003
%@ 
%C United Kingdom
%I 
%V 11
%I Pergamon Elsevier
%P 5401-5408
%E 


%0 Journal Article
%~ IRMA
%A Kassiou, Michael
%A Loc'h, Christian
%A Bottlaender, Michel
%A Mardon, Karine
%A Ottaviani, Michelle
%A Coulon, Christine
%A Katsifis, AG
%A Maziere, Bernard
%T (+)-[76Br]A-69024: a non-benzazepine radioligand for studies of dopamine D1 receptors using PET
%B Nuclear Medicine and Biology
%D 2002
%@ 
%C United States
%I 
%V 29
%I Elsevier
%P 295-302
%E 


%0 Journal Article
%~ IRMA
%A Kassiou, Michael
%A Bottlaender, Michel
%A Loc'h, Christian
%A Dolle, Frederic
%A Musachio, John L.
%A Coulon, Christine
%A Ottaviani, Michelle
%A Dannals, Robert F.
%A Maziere, Bernard
%T Pharmacological evaluation of a Br-76 analog of epibatidine: a potent ligand for studying brain nicotinic acetylcholine receptors
%B Synapse (New York)
%D 2002
%@ 
%C United States
%I 
%V 45
%I John Wiley & Sons
%P 95-104
%E 


%0 Journal Article
%~ IRMA
%A Kassiou, Michael
%A Loc'h, Christian
%A Dolle, Frederic
%A Musachio, John L.
%A Dolci, L.
%A Crouzel, C.
%A Dannals, Robert F.
%A Maziere, Bernard
%T Preparation of a bromine-76 labelled analogue of epibatidine: a potent ligand for nicotinic acetylcholine receptor studies
%B Applied Radiation and Isotopes
%D 2002
%@ 
%C United Kingdom
%I 
%V 57
%I Pergamon
%P 713-717
%E 


%0 Journal Article
%~ IRMA
%A Kassiou, Michael
%A Eberl, Stefan
%A Meikle, S
%A Birrell, Alex M
%A Constable, Christopher J.
%A Fulham, M
%A Wong, D
%A Musachio, John L.
%T In vivo imaging of nicotinic receptor upregulation following chronic (-)-nicotine treatment in baboon using SPECT
%B Nuclear Medicine and Biology
%D 2001
%@ 
%C United States
%I 
%V 28
%I Elsevier
%P 165-175
%E 


%0 Journal Article
%~ IRMA
%A Kassiou, Michael
%A Mardon, Karine
%A Mattner,, F
%A Katsifis, AG
%A Dikic, B
%T Pharmacological evaluation of (+)-2-[123I]A-69024: A radioligand for in vivo studies of dopamine D1 receptors
%B Life Sciences
%D 2001
%@ 
%C USA
%I 
%V 69
%I Elsevier
%P 669-675
%E 


%0 Journal Article
%~ IRMA
%A Liu, Xiang
%A Christie, MacDonald
%A Kassiou, Michael
%A Nuwayhid, S
%A Werling, L
%T Trishomocubanes: Novel sigma-ligands modulate amphetamine-stimulated [3H]dopamine release
%B European Journal of Pharmacology
%D 2001
%@ 
%C Amsterdam
%I 
%V 422
%I Elsevier Science
%P 39-45
%E 


%0 Journal Article
%~ IRMA
%A Liu, Xiang
%A Kassiou, Michael
%A Christie, MacDonald
%A Hambley, Trevor
%T Trishomocubanes: requirements for sigma receptor binding and subtype selectivity
%B Australian Journal of Chemistry: an international journal for chemical science
%D 2001
%@ 
%C Australia
%I 
%V 54
%I CSIRO Publishing
%P 31-36
%E