Professor Dale Bailey
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Qualifications: PhD BAppSc(Hons) MAppSc FIPEM FACPSEM CSci (UK) ARCP (Lond) Positions held:
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Biography
Dale's interests are in the development of quantitative techniques using imaging of in vivo radionuclide tracers and development of multi-modality imaging methodology. He has extensive experience in both single photon tomography (SPECT) and positron emission tomography (PET). He was instrumental in developing simultaneous emission/transmission scanning on the gamma camera using the scanning radionuclide line source approach, which has now been implemented by nearly all manufacturers. In 2004 he led a team in developing Australia's first integrated SPECT and diagnostic X-ray CT scanner for combined imaging of anatomy and physiological function. It has also been used extensively by researchers in respiratory physiology, stem cell transplantation and radiotherapy. Dale has had numerous clinical collaborations most notably in functional neuro-imaging, cardiology and in respiratory medicine. He has been actively involved in developing techniques to measure cerebral activation in PET, assessing aerosol distribution in vivo using 3D methods, measuring changes in mucus clearance rates after therapeutic interventions, and in mapping airways ventilation patterns.
Selected Publications
- Spinks TJ, Jones T, Bailey DL, Townsend DW, Grootoonk S, Bloomfield PM, Gilardi M-C, Sipe B, Reed J: Physical performance of a positron tomograph for brain imaging with retractable septa. Phys Med Biol 1992;37:1637-1655.
- Morrish PK, Rakshi JS, Bailey DL, Sawle GV, Brooks DJ: Measuring the rate of progression and estimating the preclinical period of Parkinson's disease with [18F]dopa PET. J Neurol Neurosurg Psychiatry 1998;64:314-319.
- Bailey DL, Hutton BF, Walker PJ: Improved SPECT using simultaneous emission and transmission tomography. J Nucl Med 1987;28:844-851.
- Tan P, Bailey DL, Meikle SR, Eberl S, Fulton RR, Hutton BF: A scanning line source for simultaneous emission and transmission measurements in SPECT. J Nucl Med 1993;34:1752-1760.
- Townsend DW, Geissbühler A, Defrise M, Hoffman EJ, Spinks TJ, Bailey DL, Gilardi M-C, Jones T: Fully Three-Dimensional Reconstruction for a PET Camera with Retractable Septa. IEEE Trans Med Imag 1991;10:505-512.
- Meikle SR, Hutton BF, Bailey DL: A transmission dependent method for scatter correction in SPECT. J Nucl Med 1994;35:360-367.
- Spinks TJ, Jones T, Bloomfield PM, Bailey DL, Miller MP, Hogg D, Jones WF, Vaigneur K, Reed J, Young J, Newport D, Moyers C, Casey ME, Nutt R: Physical characteristics of the ECAT EXACT3D positron tomograph. Phys Med BIol 2000;45:2601-2618.
- Rakshi JS, Uema T, Ito K, Bailey DL, Morrish PK, Ashburner J, Dagher A, Jenkins IH, Friston KJ, Brooks DJ: Frontal, midbrain and striatal dopaminergic function in early and advanced Parkinson's disease: A 3D 18F-dopa PET study. Brain 1999;122:1637-1650.
Selected Grants
- 2004 "New Imaging Instrumentation and Algorithms for the Simultaneous Measurement of Multiple Radio-labelled Probes in vivo" Australian Research Council Discovery Grant (DP0666239) (with A/Professor Steve Meikle and Professor Richard Banati), $526,753 over 3 years
- 2004 "Lung function tests to predict radiation lung injury and guide the design of radiotherapy for radical treatment of lung cancer" NSW Cancer Institute Research Foundation Grant (with A/Professor Jenny Cox) $27,090
- 2008 "The Development of Temporally Resolved Imaging of the Lung" - NSAHS Research Grants Program (2008-33) (with Dr Greg King) $40,000
- 2008 "Upgrading of SPECT/CT scanner to multi-detector CT capability" - NSAHS Cancer Key Area Grant (with Clin. Associate Professor Paul Roach), $50,000
- 2008 "Determination of the clinical correlates of lymphoedema: A pilot study". National Breast Cancer Fund. $118,424 (with Sharon Kilbreath (Discipline of Physiotherapy, University of Sydney), LC Ward, KM Refshauge et al.)