Professor Steven Meikle
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Qualifications: B.App.Sc.(hons), Ph.D.. Positions held:
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Biography
Steven Meikle is Professor of Medical Imaging Physics and Head of the Imaging Physics Laboratory at the Brain and Mind Research Institute, which is a node of the NCRIS-funded National Imaging Facility. He received his Bachelor of Applied Physics degree (Hons 1, University Medal) from the University of Technology, Sydney in 1988 and his Ph.D. degree from the Graduate School of Biomedical Engineering, University of New South Wales in 1995. He was a medical physicist at Royal Prince Alfred Hospital in Sydney (1987-2004), a visiting research associate at the Division of Nuclear Medicine and Biophysics, UCLA School of Medicine in Los Angeles (1991-2) and a post doctoral research scientist at the MRC Cyclotron Unit, Hammersmith Hospital in London (1995-6) before joining the University of Sydney in 2004. Steven is a Fellow of the Australian Institute of Physics, a Senior Member of the IEEE and a Visiting Professorial Fellow at the Centre for Medical Radiation Physics at the University of Wollongong. He serves on the International Advisory Board of the journal Physics in Medicine and Biology, the ANSTO Life Sciences Advisory Committee and is Co-Director of the Ramaciotti Imaging Centre at the Brain and Mind Research Institute.
Teaching and Service Responsibilities
Professor Meikle teaches medical imaging physics in the Graduate Entry Masters (MRS) degrees and led the development of the Master of Molecular Imaging degree, for which he is Course Director. He has previously served as Head of the Discipline of Medical Radiation Sciences.
Research Opportunities
Selected Publications
- Chan, C., Fulton, R., Feng, D. D. & Meikle, S. 2009. Regularized image reconstruction with an anatomically adaptive prior for positron emission tomography. Phys Med Biol, 54, 7379-7400.
- Kyme, A. Z., Zhou, V. W., Meikle, S. R., Baldock, C. & Fulton, R. R. 2011. Optimised motion tracking for positron emission tomography studies of brain function in awake rats. PLoS ONE, 6, e21727. doi:10.1371/journal.pone.0021727.
- Lehnert, W., Gregoire, M.-C., Reilhac, A. & Meikle, S. R. 2011. Analytical positron range modelling in heterogeneous media for PET Monte Carlo Simulation. Phys Med Biol, 56, 3313–3335.
- Lin, J. & Meikle, S. R. 2011. SPECT using asymmetric pinholes with truncated projections. Phys Med Biol, 56, 4103-4118.
- Meikle, S. R., Bailey, D. L., Hooper, P. K., Eberl, S., Hutton, B. F., Jones, W. F., Fulton, R. R. & Fulham, M. J. 1995. Simultaneous emission and transmission measurements for attenuation correction in whole body PET. J Nucl Med, 36, 1680-1688.
- Meikle, S. R., Beekman, F. J. & Rose, S. E. 2006. Complementary molecular imaging technologies: High resolution SPECT, PET and MRI. Drug Discov Today: Technol, 3, 187-194.
- Meikle, S. R., Dahlbom, M. & Cherry, S. R. 1993. Attenuation correction using count-limited transmission data in positron emission tomography. J Nucl Med, 34, 143-150.
- Meikle, S. R., Kench, P., Kassiou, M. & Banati, R. B. 2005. Small animal SPECT and its place in the matrix of molecular imaging technologies. Phys Med Biol, 50, R45-R61.
Selected Grants
- Meikle SR, Reinhard M, Weisenberger AG. Novel imaging technologies for continuous measurement of tracer kinetics in awake animals, Australian Research Council (Discovery Projects) 2011-13 ($350,000)
- Meikle SR, Fulton RR, Banati RB. Simultaneous Measurement of Brain Function and Behaviour in Fully Conscious Laboratory Animals. Australian Research Council (Discovery Projects) 2009-2011 ($330,000).
- Meikle SR, Bailey DL, Banati RB. New Imaging Instrumentation and Algorithms for the Simultaneous Measurement of Multiple Radio-labelled Probes in vivo. Australian Research Council (Discovery Projects) 2006-2008 ($526,753).
- Fulton RR, Meikle SR, Banati RB. Enabling Technologies for Motion Corrected Positron Emission Tomography (PET) of Unanaesthetized Laboratory Animals. Australian Research Council (Discovery Projects) 2006-2008 ($408,000).
- Weisenberger A, Paulus M, Pomper M, Meikle S. A novel apparatus to perform in vivo anatomical and functional imaging of radioisotope labeled molecules in non-anaesthetized, non-restrained small animals. U.S. Dept of Energy (Advanced Technology Development Program Grant) 2001-2008 (USD $4.75 million).