2011 SEIB Colloquium

Our annual SEIB colloquium was held on the 23rd and 24th of November, at the New Law School Building on Camperdown campus. The colloquium was opened by the Dean of the Sydney Medical School, Professor Bruce Robinson. The forum provided a platform to update colleagues on achievements within SEIB, allowing them to share research findings and interests, facilitate cross-disciplinary exposure and exchange of ideas, and focus on specific thematic areas that represent areas of strength that could be developed into future funding applications. Brief post-graduate student presentations and posters added impetus to discussion of the multidisciplinary nature of our work. Three main themes were explored:

1) Microbial ecology and antimicrobial resistance
2) Social networks, outbreaks & communications and
3) Food security and safety.

Leading speakers from different faculties presented their research results and personal experience, followed by interactive panel discussions to identify critical outstanding questions, areas of mutual interest and possibilities for future project proposals.

An outstanding keynote lecture on “Malaria – targeting parasite and host kinomes”, with an emphasis on kinases as potential drug targets, was delivered by Professor Christian Doerig, newly appointed head of the Department of Microbiology at Monash University, Melbourne.

The annual Beveridge lecture at the School of Veterinary Science was given by Dr David Jordan from the NSW Department of Primary Industries, on the topic of antimicrobial use in prophylaxis, pre-emptive and targeted therapy in livestock and companion animals, with an emphasis on methicillin resistant Staphyloccus aureus (MRSA) infections. In a stimulating address, he highlighted the need to move beyond the current narrow regulatory focus on residue levels within animal products, which is an incomplete marker of potential harm, to a broader appreciation of antibiotic-associated disturbances of microbial ecology, selection of potential pathogens and transmission between animals and humans.

Colleagues from the Social Sciences also delivered key presentations. Dr. Alana Mann from the Department of Media and Communications and A/Professor Ian Kerridge from the Centre for Values, Ethics and the Law (VELIM) led a viewpoint discussion on how the media, especially the print media, frame emerging infectious diseases. Dr. Olaf Werder explored the social ecological model as a framework when communicating about infectious diseases.

SEIB has been active during 2011 in the Asia-Pacific region. Initiatives include an NHMRC-funded tuberculosis field trial, Public Health laboratory capacity building and training in clinical skills in Vietnam; nascent collaborations with the Pasteur institute in Cambodia, capacity building in health in Timor L’Este and research collaborations in social, veterinary and health sciences in Indonesia.


Presentations

Day 1 - Wednesday, 23 November 2011

Microbial Ecology and Antimicrobial Resistance
Social Networks, Outbreaks, Communications - Influenza as model?
Student Presentations
  • Molecular targets of miltesfoine and genes involved in miltefosine resistance in yeast - presented by Chayanika Biswas || (view presentation)
  • Matrix-Assisted Laser Desorption Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF MS) for Identification of Cryptococcus neoformans and C. gattii Molecular Types - presented by Carolina Firacative || (view presentation)
  • Influenza, Wind, Humidity and Air Temperature – a survival analysis of equine influenza spread - presented by Simon Firestone || (view presentation)
  • Effective change agents: how a sense of community mediates the success of social marketing programs in Australia and Indonesia - presented by Nick Goodwin || (view presentation)
  • Evolution of the Pandemic H1N1 and Highly Pathogenic H5N1 Influenza Viruses through Proteotyping with High Resolution Mass Spectrometry - presented by Ji-Won Ha || (view presentation)
  • An exotic mosquito exploits cryptic urban habitats in southern Australia: Implications for water conservation strategies and mosquito-borne disease risk - presented by Nur Kassim || (view presentation)
  • Inhaled liposomal ciprofloxacin nanoparticles control the release of the antibiotic at Bronchial Epithelia - presented by Hui Xin Ong || (view presentation)
  • An outbreak of Methicillin-Resistant Staphylococcus aureus (MRSA) rapidly identified in a Neonatal Intensive Care Unit (NICU) using routine subtyping-based surveillance - presented by Matthew O'Sullivan || (view presentation)
  • Cost of intrinsic resistance to low concentrations of antibiotics in E.coli - presented by Katherine Phan || (view presentation)
  • PARalpha agonist WY14643 improves antiviral effect of interferon against Hepatitis C - presented by Scott Read || (view presentation)
  • Cost-effectiveness of an integrated rabies prevention and control program in humans and dogs in Bhutan: data and analytical challenges within a framework approach - presented by Tenzin Tenzin || (view presentation)
  • IRF-8 KO monocytes show defective recruitment and infiltration into the West Nile Virus-infected brain - presented by Rachel Terry || (view presentation)
  • Detection of strongyloides stercoralis in stool using the loop mediated isothermal amplification (LAMP) method - presented by Matthew Watts || (view presentation)
  • Monocyte and microparticle membrane donation to endothelial cells in a model of endotoxic shock - presented by Beryl Wen || (view presentation)
  • The cost of respiratory virus infection presenting with Influenza-like illness - Kevin Yin || (view presentation)
Do the Media drive the political agenda?
Special plenary session
  • Malaria: Plasmodium Functional Kinomies - presented by Professor Christian Doerig, Monash University || (view presentation)

Day 2 - Thursday, 24 November 2011

Food Security and Safety
Out of the box - New Collaborative Opportunities

Abstracts

The following abstracts were presented:

  • Molecular targets of Miltefosine and genes involved in Miltesfosine resistance in yeast (view abstract)
  • A survey measuring quality of life impact on parents of a child's Influenza-like-illness (view abstract)
  • Clinical utility of Posaconazole therapeutic drug monitoring (view abstract)
  • Voriconazole therapeutic drug monitoring: a multi-centre analysis (view abstract)
  • Matrix-Assisted Laser Desorption Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF MS) for identification of Cryptococcus neoformans and C. gattii molecular types (view abstract)
  • Influenza, wind, humidity and air temperature – a survival analysis of Equine Influenza spread (view abstract)
  • Finding effective change agents: how a sense of community mediates the success of social marketing programs in Australia and Indonesia (view abstract)
  • Investigation of Paediatric Astrovirus Infection: comparison of an ELISA test and nested RT-PCR assay (view abstract)
  • Evolution of the pandemic H1N1 and highly pathogenic H5N1 Influenza viruses through proteotyping with high resolution mass spectrometry (view abstract)
  • Investigating the role of mucosal dendritic cells in the response to non-lytic vaginal viral infection in a murine model (view abstract)
  • An exotic mosquito exploits cryptic urban habitats in southern Australia: implications for water conservation strategies and mosquito-borne disease risk (view abstract)
  • An unblinded randomized study of Influenza A (H1N1) 2009 resistance under standard and double dose Oseltamivir treatment: better outcome for the patient or the virus? (view abstract)
  • Endotoxin and pro-inflammatory cytokines differentially effect endothelial vesiculation: specific time sequence, cell recruitment and cytoskeletal modifications (view abstract)
  • Quantitation of hemagglutinin using a proteomics gel-based approach to aid vaccine development (view abstract)
  • Proteotyping of ParaInfluenza Virus using mass spectrometry (view abstract)
  • Costs of deep sequencing of Hepatitis C Virus to detect drug resistance mutations (view abstract)
  • An outbreak of Methicillin-Resistant Staphylococcus Aureus (MRSA) rapidly identified in a Neonatal Intensive Care Unit (NICU) using routine subtyping-based surveillance (view abstract)
  • Costs of intrinsic resistance to low concentrations of antibiotics in E. coli (view abstract)
  • PPARĪ± agonist WY14643 improves the antiviral effect of Interferon against Hepatitis C Virus (view abstract)
  • New South Wales horse managers’ perceptions of the 2007 Equine Influenza outbreak management (view abstract)
  • HCV-induced IFN- mediates increased endocannabinoid CB1 receptor expression in a cell culture model (view abstract)
  • Diagnosis of Strongyloides stercoralis in different communities in Dhaka, Bangladesh (view abstract)
  • Anti-viral inhibitor binding to Influenza Neuraminidase by mass spectrometry (view abstract)
  • Cost-effectiveness of an integrated Rabies prevention and control program in humans and dogs in Bhutan: data and analytical challenges within a framework approach (view abstract)
  • IRF-8 KO monocytes show defective recruitment and infiltration into the West Nile virus-infected brain (view abstract)
  • Detection of Strongyloides Stercoralis in stool using the Loop Mediated Isothermal Amplification (LAMP) method (view abstract)
  • Monocyte and microparticle membrane donation to endothelial cells in a model of Endotoxic Shock (view abstract)
  • Influenza infection during pregnancy: a review of incidence and outcomes (view abstract)
  • The cost of respiratory virus infection presenting with Influenza-like illness in Australian children: a prospective cohort study
    (view abstract)