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Overview of research program

Research conducted by this unit focuses on mucosal immunity, at both a molecular and cellular level. More specifically, this unit investigates the involvement of a number of genes (traditionally associated with the control of the immune response) in experimental models of idiopathic inflammatory bowel disease and atherosclerosis, with a view to gaining new insights into the mechanisms which underlie these disorders.

Major funding sources

  • Industry funding

Selected publications

  • Xu, Y., Hunt, N., Bao, S. The effect of restraint stress on experimental colitis is IFN-gamma independent. Journal of neuroimmunology. 2008; 200:53-61. Abstract
  • Zhang, X., Bao, S., Lai, D., Rapkins, R., Gillies, M. Intravitreal Triamcinolone Acetonide Inhibits Breakdown of the Blood-Retinal Barrier through Differential Regulation of VEGF-A and its Receptors in Early Diabetic Rat Retinas. Diabetes. 2008; 57:1026-33. Abstract
  • Puranik, R., Bao, S., Nobecourt, E., Nicholls, S., Dusting, G., Barter, P., Celermajer, D., Rye, K. Low dose apolipoprotein A-I rescues carotid arteries from inflammation in vivo. Atherosclerosis. 2008; 196:240-7. Abstract
  • Patel, S., Celermajer, D., Bao, S. Atherosclerosis-Underlying inflammatory mechanisms and clinical implications. The international journal of biochemistry & cell biology. 2008; 40:576-80. Abstract
  • Pearson, R., Fleetwood, J., Eaton, S., Crossley, M., Bao, S. Kruppel-like transcription factors: A functional family. The international journal of biochemistry & cell biology. 2008; 40:1996-2001. Abstract
  • Tavakoli, N., Hambly, B., Sullivan, D., Bao, S. Forkhead box protein 3: Essential immune regulatory role. The international journal of biochemistry & cell biology. 2008; 40:2369-73.