Research Grants

2014 National Health and Medical Research Council (NHMRC) Grants

The Sydney Children's Hospitals Network (SCHN) researchers who have been awarded a 2014 National Health and Medical Research Council (NHMRC) Grant.

Project Grants - Chief Investigator A (CIA) from SCHN

Chief Investigators: Prof Ian Alexander, Prof Adrian Thrasher
Project Title: Reconstitution of B-cell ontogeny in Btk-deficient patient-derived CD34+ cells in a humanised mouse model: The foundations for an Australian XLA gene therapy trial
Total Awarded: $656,226

Chief Investigators: Prof Ian Alexander, Prof Andras Nagy, A/Prof Kevin Carpenter
Project Title: Development of a novel hybrid rAAV/transposon gene delivery system for life-long correction of metabolic liver disease in infants and children
Total Awarded: $489,169

Chief Investigators: Prof Adam Jaffe, Dr Thomas Snelling, Prof Gwendolyn Gilbert, A/Prof Stephen Lambert, Dr Melanie Wong
Project Title: Evaluation of the effectiveness of the 13-valent pneumococcal conjugate vaccine on pneumococcal serotypes causing pneumonia in children
Total Awarded: $1,091,024

Chief Investigators: Dr David Ziegler, Prof Philip Hogg, A/Prof Andrew Kung
Project Title: Targeting mitochondrial metabolism in Diffuse Intrinsic Pontine Gliomas as a novel therapeutic strategy
Total Awarded: $587,562

Chief Investigators: Dr Charles Verge, Dr Shihab Hameed, Prof Claire Wainwright, Prof Jennifer Couper
Project Title: Cystic Fibrosis - Insulin Deficiency, Early Action (CF-IDEA)
Total Awarded: $180,758

Project Grants - CIA from external organisations

Chief Investigators: Dr Paul Baldock, Prof David Little, Dr Aaron Schindeler, Prof Peter Croucher
Project Title: Sclerostin and Dickkopf-1 in regulation of bone mass
Total Awarded: $617,562

Chief Investigators: A/Prof Yves d'Udekem d'Acoz, A/Prof David Winlaw, Prof Paul Monagle, Dr Nadine Kasparian, A/Prof Michael Cheung, A/Prof Robert Weintraub, Prof Igor Konstantinov, Dr Julian Ayer, Dr Mark Mackay
Project Title: Improving functional outcomes after Fontan surgery by a cross-sectional study of the outcomes following variation in practice in Australia and New Zealand: focus on anticoagulation and cardiac shunting by the fenestration
Total Awarded: $743,660

Chief Investigators: Dr Steven Tong, Prof Stephen Locarnini, Dr Joshua Davis, A/Prof Gail Garvey, A/Prof John Condon, Dr Margaret Littlejohn, Dr Nicholas Wood, Dr Nadia Warner, Dr Renae Walsh
Project Title: A novel Hepatitis B virus genotype in Indigenous Australians: impact on vaccine efficacy and clinical outcomes
Total Awarded: $1,065,763

Chief Investigators: Prof Kathryn North, Prof David Bishop, Dr Stewart Head, Dr Kate Quinlan
Project Title: The effects of actinin-3 on muscle metabolism, human health and disease
Total Awarded: $621,894

Chief Investigators: Dr Helen Liley, A/Prof Rod Hunt, A/Prof Susan Jacobs, Prof Nadia Badawi, A/Prof Iona Novak, A/Prof Lisa Askie, A/Prof Malcolm Battin, Dr Rachel O'Connell
Project Title: Preventing Adverse Outcomes of Neonatal Hypoxic Ischaemic Encephalopathy with Erythropoietin: A Randomised Controlled Multicentre Australian Trial
Total Awarded: $2,010,583

Chief Investigators: Prof Rebecca Ivers, Prof Andrew Holland, Prof Roy Kimble, Prof Kathleen Clapham, Doctor Serigne Lo, Dr John Daniels Redfern, Ms Delia Hendrie
Project Title: Understanding burn injuries in Aboriginal and Torres Strait Islander children: treatment, access to services and outcomes.
Total Awarded: $872,801

Chief Investigators: Dr Rosemary Sutton, Dr Luciano Dalla-Pozza, A/Prof Tamas Revesz
Project Title: Improving risk evaluation and outcomes in paediatric acute lymphoblastic leukaemia
Total Awarded: $771,596

Chief Investigators: Dr Guillaume Lessene, Dr Nadia Kershaw, Prof Maria Kavallaris
Project Title: Chemical and structural biology validation of Lamin B1 as a new anti-cancer target
Total Awarded: $617,562

Partnership Grant

Chief Investigators: Prof Jeffrey Braithwaite, Prof Adam Jaffe, Prof Les White, Prof Chris Cowell, Prof Mark Harris
Project Title: The appropriateness of healthcare delivered to Australian children: CareTrack Kids
Total Awarded: $1,263,318

Practitioner Fellowships

Chief Investigator: A/Prof Russell Dale
Total Awarded: $387,432

Research Fellowships

Chief Investigator: Prof Maria Kavallaris
Total Awarded: $601,420

Chief Investigator: Prof Richard Lock
Total Awarded: $601,420

Career Development Fellowships

Chief Investigator: Dr Nicolas Wood
Total Awarded: $283,419

Chief Investigator: Dr Claire Wakefield
Total Awarded: $404,884