Adjunct Associate Professor Edna Hardeman

Adjunct Associate Professor
Medicine, Children's Medical Research Institute

T: 02 8865 2913
F: 02 687 2120

Research interests

Associate Professor Edna Hardeman is an internationally recognised expert in muscle biology and disease and more recently researches the neurodevelopmental disorder Williams Syndrome.


2014 | 2013 | 2011 | 2009 | 2008


  • Curthoys, N., Freittag, H., Connor, A., Desouza, M., Brettle, M., Poljak, A., Hall, A., Hardeman, E., Schevzov, G., Gunning, P., Fath, T. (2014), Tropomyosins induce neuritogenesis and determine neurite branching patterns in B35 neuroblastoma cells. Molecular and Cellular Neurosciences. 58, 11-21. [Abstract]
  • Head, S., Houweling, P., Chan, S., Chen, G., Hardeman, E. (2014), Properties of regenerated mouse extensor digitorum longus muscle following notexin injury. Experimental Physiology. 99(4), 664-674. [Abstract]


  • Stehn, J., Haass, N., Bonello, T., Desouza, M., Kottyan, G., Treutlein, H., Zeng, J., Nascimento, P., Sequeira, V., Butler, T., Allanson, M., Fath, T., Hill, T., McCluskey, A., Schevzov, G., Palmer, S., Hardeman, E., Winlaw, D., Reeve, V., Dixon, I., Weninger, W., Cripe, T., Gunning, P. (2013), A Novel Class of Anticancer Compounds Targets the Actin Cytoskeleton in Tumor Cells. Cancer Research. 73(16), 5169-5182. [Abstract]
  • Lindqvist, J., Cheng, A., Renaud, G., Hardeman, E., Ochala, J. (2013), Distinct Underlying Mechanisms of Limb and Respiratory Muscle Fiber Weaknesses in Nemaline Myopathy. Journal of Neuropathology and Experimental Neurology. 72(6), 472-481. [Abstract]
  • Lee, A., Anderson, J., Joya, J., Head, S., Pather, N., Kee, A., Gunning, P., Hardeman, E. (2013), Aged skeletal muscle retains the ability to fully regenerate functional architecture. Bioarchitecture. 3(2), 25-37. [Abstract]


  • Nguyen, M., Joya, J., Kee, A., Domazetovska, A., Yang, N., Hook, J., Lemckert, F., Kettle, E., Valova, V., Robinson, P., North, K., Gunning, P., Mitchell, C., Hardeman, E. (2011), Hypertrophy and dietary tyrosine ameliorate the phenotypes of a mouse model of severe nemaline myopathy. Brain. 134(Pt 12), 3516-3529. [Abstract]


  • Vlahovich, N., Kee, A., Van der Poel, C., Kettle, E., Hernandez-Deviez, D., Lucas, C., Lynch, G., Parton, R., Gunning, P., Hardeman, E. (2009), Cytoskeletal Tropomyosin Tm5NM1 Is Required for Normal Excitation-contraction Coupling in Skeletal Muscle. Molecular biology of the cell. 20(1), 400-9. [Abstract]


  • Chang, A., Hook, J., Lemckert, F., McDonald, M., Nguyen, M., Hardeman, E., Little, D., Gunning, P., Reddel, R. (2008), The murine stanniocalcin 2 gene is a negative regulator of postnatal growth. Endocrinology. 149(5), 2403-2410. [Abstract]
  • MacArthur, D., Seto, J., Chan, S., Quinlan, K., Raftery, J., Turner, N., Nicholson, M., Kee, A., Hardeman, E., Gunning, P., Cooney, G., Head, S., Yang, N., North, K. (2008), An Actn3 knockout mouse provides mechanistic insights into the association between alpha-actinin-3 deficiency and human athletic performance. Human Molecular Genetics. 17(8), 1076-1086. [Abstract]
  • Schevzov, G., Fath, T., Vrhovski, B., Vlahovich, N., Rajan, S., Hook, J., Joya, J., Lemckert, F., Puttur, F., Lin, J., Hardeman, E., Wieczorek, D., O'Neill, G., Gunning, P. (2008), Divergent regulation of the sarcomere and the cytoskeleton. The Journal of biological chemistry. 283(1), 275-83. [Abstract]
  • Kee, A., Hardeman, E. (2008), Tropomyosins in skeletal muscle diseases. Advances in experimental medicine and biology. 644, 143-157. [Abstract]
  • Nguyen, M., Hardeman, E. (2008), Mouse Models for Thin Filament Disease. In: The Sarcomere and Skeletal Muscle Disease. (pp.66-77).United States: Springer.
  • Vlahovich, N., Schevzov, G., Nair-Shaliker, V., Ilkovski, B., Artap, S., Joya, J., Kee, A., North, K., Gunning, P., Hardeman, E. (2008), Tropomyosin 4 defines novel filaments in skeletal muscle associated with muscle remodelling/regeneration in normal and diseased muscle. Cell motility and the cytoskeleton. 65(0), 73-85. [Abstract]
  • Gunning, P., O'Neill, G., Hardeman, E. (2008), Tropomyosin-based regulation of the actin cytoskeleton in time and space. Physiological Reviews. 88(1), 1-35. [Abstract]