Clinical neurophysiology group

Lab head: Dr John Burne
Location: Cumberland campus

This group aims to apply neurophysiology and biomechanical methods to clinical problems in management of patients with movement disorders such as parkinsonism

Lab members: Dr Con Yiannikas, Neurology Department, Concord Hospital and private neurology practice. Dr Dennis Cordato, Neurology Department, Liverpool Hospital.

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Muscle rigidity and tremor in neurological disease esp.Parkinson's disease, peripheral neuropathy and rheumatoid arthritis

Primary supervisor: John Burne

We are studying the adaptive role of muscle stretch reflexes in normal movements and movement disorders. In particular we are looking at the contribution of the abnormal reflex response to the rigidity and tremor of Parkinson's disease, neuropathy , spasticity following stroke and rheumatoid arthritis. Muscle reflexes strongly influence the biomechanics of the limb and thus performance in different tasks.  Parallel measures of limb biomechanics (joint stiffness, force and velocity relationships) and reflex activity (extracted from surface EMG) are used to make clinically relevant measures of neurological disability and drug response in patients. The honours project will be defined from this broad field after student consultation.

Discipline: Biomedical Sciences
Keywords: Movement disorders, Neurophysiology, Neuromuscular diseases